Conservation of cofitness between PP_0850 and PP_4891 in Pseudomonas putida KT2440

83 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_0850 Dual-specificity RNA methyltransferase RlmN 1.0 PP_4891 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex 0.32 9
Pseudomonas fluorescens FW300-N2C3 0.88 AO356_06605 23S rRNA (adenine(2503)-C2)-methyltransferase 0.86 AO356_08640 membrane protease HflC low > 104
Pseudomonas fluorescens FW300-N2E2 0.88 Pf6N2E2_3181 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) 0.86 Pf6N2E2_3611 HflC protein
Pseudomonas sp. RS175 0.88 PFR28_00294 Dual-specificity RNA methyltransferase RlmN 0.82 PFR28_05124 Modulator of FtsH protease HflC low > 88
Pseudomonas fluorescens FW300-N2E3 0.87 AO353_15875 23S rRNA (adenine(2503)-C2)-methyltransferase 0.87 AO353_13160 membrane protease HflC low > 101
Pseudomonas fluorescens GW456-L13 0.87 PfGW456L13_4865 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) 0.86 PfGW456L13_151 HflC protein low > 87
Pseudomonas fluorescens SBW25 0.87 PFLU_RS24815 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.85 PFLU_RS02585 protease modulator HflC low > 109
Pseudomonas fluorescens SBW25-INTG 0.87 PFLU_RS24815 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.85 PFLU_RS02585 protease modulator HflC low > 109
Pseudomonas fluorescens FW300-N1B4 0.87 Pf1N1B4_857 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) 0.87 Pf1N1B4_1409 HflC protein
Pseudomonas simiae WCS417 0.87 PS417_23160 50S rRNA methyltransferase 0.81 PS417_02505 membane protease HflC
Pseudomonas syringae pv. syringae B728a 0.86 Psyr_1245 23S rRNA m(2)A-2503 methyltransferase 0.88 Psyr_0575 protease FtsH subunit HflC low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.86 Psyr_1245 23S rRNA m(2)A-2503 methyltransferase 0.88 Psyr_0575 protease FtsH subunit HflC low > 86
Pseudomonas sp. S08-1 0.85 OH686_17515 23S rRNA (adenine(2503)-C(2))-methyltransferase 0.77 OH686_09455 HflC protein low > 80
Pseudomonas stutzeri RCH2 0.84 Psest_1259 23S rRNA m2A2503 methyltransferase 0.76 Psest_0686 Membrane protease subunits, stomatin/prohibitin homologs
Marinobacter adhaerens HP15 0.66 HP15_1490 conserved hypothetical protein 0.55 HP15_2496 HflC low > 73
Kangiella aquimarina DSM 16071 0.57 B158DRAFT_1149 23S rRNA m2A2503 methyltransferase 0.38 B158DRAFT_1955 HflC protein low > 40
Lysobacter sp. OAE881 0.56 ABIE51_RS09415 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.38 ABIE51_RS06555 protease modulator HflC low > 62
Escherichia coli Nissle 1917 0.56 ECOLIN_RS14300 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 ECOLIN_RS24245 protease modulator HflC
Escherichia coli ECRC98 0.56 JDDGAC_25385 rlmN bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 JDDGAC_15880 hflC protease modulator HflC
Escherichia coli BL21 0.56 ECD_02409 dual specificity 23S rRNA m(2)A2503, tRNA m(2)A37 methyltransferase, SAM-dependent 0.38 ECD_04042 HflB protease modulator specific for phage lambda cII repressor low > 60
Escherichia fergusonii Becca 0.56 EFB2_01373 Dual-specificity RNA methyltransferase RlmN 0.38 EFB2_04360 Modulator of FtsH protease HflC low > 86
Escherichia coli ECRC102 0.56 NIAGMN_19480 rlmN bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 NIAGMN_10090 hflC protease modulator HflC
Escherichia coli ECRC101 0.56 OKFHMN_21710 rlmN bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 OKFHMN_12240 hflC protease modulator HflC
Escherichia coli ECOR27 0.56 NOLOHH_13360 rlmN bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 NOLOHH_04505 hflC protease modulator HflC
Escherichia coli ECRC62 0.56 BNILDI_12160 rlmN bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 BNILDI_06985 hflC protease modulator HflC
Escherichia coli ECOR38 0.56 HEPCGN_20830 rlmN bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 HEPCGN_10470 hflC protease modulator HflC low > 85
Escherichia coli BW25113 0.56 b2517 yfgB predicted enzyme (NCBI) 0.38 b4175 hflC modulator for HflB protease specific for phage lambda cII repressor (NCBI) low > 76
Escherichia coli ECRC99 0.56 KEDOAH_06510 rlmN bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 KEDOAH_15915 hflC protease modulator HflC
Escherichia coli ECRC101 0.56 MCAODC_12240 rlmN bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 MCAODC_02755 hflC protease modulator HflC
Escherichia coli HS(pFamp)R (ATCC 700891) 0.55 OHPLBJKB_01192 Dual-specificity RNA methyltransferase RlmN 0.38 OHPLBJKB_03867 Modulator of FtsH protease HflC low > 73
Enterobacter asburiae PDN3 0.55 EX28DRAFT_0126 23S rRNA (adenine(2503)-C(2))-methyltransferase 0.36 EX28DRAFT_3372 HflC protein low > 76
Enterobacter sp. TBS_079 0.55 MPMX20_03395 Dual-specificity RNA methyltransferase RlmN 0.38 MPMX20_00456 Modulator of FtsH protease HflC low > 85
Klebsiella michiganensis M5al 0.55 BWI76_RS21095 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 BWI76_RS02550 protease modulator HflC low > 92
Dickeya dadantii 3937 0.55 DDA3937_RS15480 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.37 DDA3937_RS18595 protease modulator HflC
Pectobacterium carotovorum WPP14 0.55 HER17_RS06085 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.39 HER17_RS02600 protease modulator HflC low > 75
Serratia liquefaciens MT49 0.54 IAI46_19290 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.39 IAI46_01640 protease modulator HflC low > 86
Dickeya dianthicola ME23 0.54 DZA65_RS16665 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.37 DZA65_RS19665 protease modulator HflC low > 75
Rahnella sp. WP5 0.54 EX31_RS20525 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.37 EX31_RS08805 protease modulator HflC low > 89
Cupriavidus basilensis FW507-4G11 0.54 RR42_RS13155 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.42 RR42_RS13100 membrane protein
Dickeya dianthicola 67-19 0.54 HGI48_RS15590 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.37 HGI48_RS18530 protease modulator HflC low > 71
Erwinia tracheiphila SCR3 0.54 LU632_RS17815 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.38 LU632_RS02070 hflC protease modulator HflC low > 74
Shewanella sp. ANA-3 0.54 Shewana3_1226 hypothetical protein (RefSeq) 0.46 Shewana3_0600 HflC protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.54 SO3315 conserved hypothetical protein TIGR00048 (NCBI ptt file) 0.46 SO0606 hflC hflC protein (NCBI ptt file) low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.54 GFF2414 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) 0.38 GFF828 HflC protein low > 78
Ralstonia sp. UNC404CL21Col 0.54 ABZR87_RS10900 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.39 ABZR87_RS10955 protease modulator HflC low > 80
Dechlorosoma suillum PS 0.54 Dsui_3145 23S rRNA m2A2503 methyltransferase 0.48 Dsui_3134 membrane protease subunit, stomatin/prohibitin
Ralstonia solanacearum PSI07 0.54 RPSI07_RS18115 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.41 RPSI07_RS18060 protease modulator HflC low > 81
Ralstonia solanacearum GMI1000 0.54 RS_RS06070 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.40 RS_RS06125 protease modulator HflC
Ralstonia solanacearum IBSBF1503 0.54 RALBFv3_RS15260 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.40 RALBFv3_RS15315 protease modulator HflC
Ralstonia solanacearum UW163 0.54 UW163_RS12725 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.40 UW163_RS12780 protease modulator HflC
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS00070 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.42 LRK54_RS00615 protease modulator HflC low > 59
Rhodanobacter denitrificans MT42 0.53 LRK55_RS18065 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.42 LRK55_RS00385 protease modulator HflC low > 63
Shewanella amazonensis SB2B 0.53 Sama_2368 hypothetical protein (RefSeq) 0.45 Sama_3022 hflC protein (RefSeq) low > 62
Shewanella loihica PV-4 0.53 Shew_1287 hypothetical protein (RefSeq) 0.45 Shew_0569 HflC protein (RefSeq) low > 60
Xanthomonas campestris pv. campestris strain 8004 0.53 Xcc-8004.2737.1 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) 0.41 Xcc-8004.3954.1 HflC protein low > 74
Rhodanobacter sp. FW510-T8 0.53 OKGIIK_07140 rlmN 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.46 OKGIIK_06645 hflC protease modulator HflC low > 52
Pantoea sp. MT58 0.53 IAI47_05040 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.39 IAI47_02605 protease modulator HflC low > 76
Dyella japonica UNC79MFTsu3.2 0.53 ABZR86_RS05455 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.40 ABZR86_RS08350 protease modulator HflC low > 74
Vibrio cholerae E7946 ATCC 55056 0.53 CSW01_03930 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.40 CSW01_01850 protease modulator HflC low > 62
Paraburkholderia sabiae LMG 24235 0.53 QEN71_RS05965 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.27 QEN71_RS06015 protease modulator HflC low > 153
Paraburkholderia bryophila 376MFSha3.1 0.52 H281DRAFT_00514 23S rRNA m(2)A-2503 methyltransferase 0.32 H281DRAFT_00524 protease FtsH subunit HflC
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS12590 dual-specificity RNA methyltransferase RlmN 0.28 BPHYT_RS12540 membrane protein
Paraburkholderia graminis OAS925 0.52 ABIE53_002744 23S rRNA (adenine2503-C2)-methyltransferase 0.32 ABIE53_002734 membrane protease subunit HflC low > 113
Herbaspirillum seropedicae SmR1 0.51 HSERO_RS14810 50S rRNA methyltransferase 0.42 HSERO_RS14760 membrane protein
Acidovorax sp. GW101-3H11 0.51 Ac3H11_1791 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) 0.35 Ac3H11_1802 HflC protein low > 79
Alteromonas macleodii MIT1002 0.50 MIT1002_02791 Dual-specificity RNA methyltransferase RlmN 0.48 MIT1002_03785 Modulator of FtsH protease HflC low > 70
Hydrogenophaga sp. GW460-11-11-14-LB1 0.50 GFF4866 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) 0.30 GFF4855 HflC protein low > 90
Variovorax sp. OAS795 0.49 ABID97_RS14210 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.34 ABID97_RS14265 protease modulator HflC low > 91
Variovorax sp. SCN45 0.49 GFF992 23S rRNA (adenine(2503)-C(2))-methyltransferase @ tRNA (adenine(37)-C(2))-methyltransferase (EC 2.1.1.192) 0.33 GFF1003 HflC protein low > 127
Castellaniella sp019104865 MT123 0.49 ABCV34_RS02610 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.36 ABCV34_RS02665 protease modulator HflC
Azospirillum brasilense Sp245 0.46 AZOBR_RS00800 50S rRNA methyltransferase 0.36 AZOBR_RS06525 membrane protein low > 97
Azospirillum sp. SherDot2 0.46 MPMX19_02413 Dual-specificity RNA methyltransferase RlmN 0.41 MPMX19_01250 Modulator of FtsH protease HflC
Phaeobacter inhibens DSM 17395 0.44 PGA1_c36240 ribosomal RNA large subunit methyltransferase N 0.35 PGA1_c23700 protein HflC low > 62
Agrobacterium fabrum C58 0.43 Atu2673 hypothetical protein 0.31 Atu2044 HFLC protein low > 89
Dinoroseobacter shibae DFL-12 0.43 Dshi_3311 radical SAM enzyme, Cfr family (RefSeq) 0.34 Dshi_2735 HflC protein (RefSeq) low > 64
Magnetospirillum magneticum AMB-1 0.42 AMB_RS05715 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.40 AMB_RS17655 protease modulator HflC
Rhodopseudomonas palustris CGA009 0.42 TX73_002060 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.40 TX73_018075 protease modulator HflC low > 86
Sinorhizobium meliloti 1021 0.41 SMc03831 hypothetical protein 0.29 SMc01440 hydrolase serine protease transmembrane protein low > 103
Sphingomonas koreensis DSMZ 15582 0.41 Ga0059261_1407 23S rRNA (adenine(2503)-C(2))-methyltransferase 0.23 Ga0059261_1381 Membrane protease subunits, stomatin/prohibitin homologs low > 68
Bosea sp. OAE506 0.41 ABIE41_RS04880 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.33 ABIE41_RS12855 protease modulator HflC low > 77
Rhizobium sp. OAE497 0.41 ABIE40_RS18200 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 0.26 ABIE40_RS11530 protease modulator HflC low > 107
Desulfovibrio vulgaris Miyazaki F 0.32 DvMF_1431 radical SAM enzyme, Cfr family (RefSeq) 0.38 DvMF_2675 HflC protein (RefSeq) low > 51
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU2904 radical SAM enzyme, Cfr family (TIGR) 0.37 DVU0683 hflC protein, putative (TIGR) low > 55
Echinicola vietnamensis KMM 6221, DSM 17526 0.29 Echvi_0755 23S rRNA m2A2503 methyltransferase 0.24 Echvi_2032 HflC protein low > 79

Not shown: 16 genomes with orthologs for PP_0850 only; 1 genomes with orthologs for PP_4891 only