Conservation of cofitness between PFLU_RS02430 and PFLU_RS28420 in Pseudomonas fluorescens SBW25

89 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas fluorescens SBW25 1.0 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 1.0 PFLU_RS28420 thiazole synthase 0.89 1
Pseudomonas fluorescens SBW25-INTG 1.00 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 1.00 PFLU_RS28420 thiazole synthase 0.90 2
Pseudomonas simiae WCS417 0.98 PS417_02355 thiamine biosynthesis protein ThiC 1.00 PS417_26775 thiazole synthase 0.63 1
Pseudomonas fluorescens FW300-N2E3 0.95 AO353_13010 thiamine biosynthesis protein ThiC 0.96 AO353_08215 thiazole synthase 0.64 6
Pseudomonas syringae pv. syringae B728a 0.95 Psyr_0544 hydroxymethylpyrimidine synthase 0.91 Psyr_4740 thiazole-phosphate synthase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.95 Psyr_0544 hydroxymethylpyrimidine synthase 0.91 Psyr_4740 thiazole-phosphate synthase 0.42 65
Pseudomonas fluorescens FW300-N2E2 0.95 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.95 Pf6N2E2_4590 Thiazole biosynthesis protein ThiG 0.77 1
Pseudomonas fluorescens FW300-N2C3 0.94 AO356_08810 thiamine biosynthesis protein ThiC 0.95 AO356_13375 thiazole synthase 0.42 7
Pseudomonas fluorescens FW300-N1B4 0.94 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.96 Pf1N1B4_2331 Thiazole biosynthesis protein ThiG 0.55 4
Pseudomonas sp. RS175 0.94 PFR28_05091 Phosphomethylpyrimidine synthase 0.95 PFR28_04252 Thiazole synthase 0.96 1
Pseudomonas fluorescens GW456-L13 0.94 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.99 PfGW456L13_1000 Thiazole biosynthesis protein ThiG 0.90 1
Pseudomonas putida KT2440 0.91 PP_4922 Phosphomethylpyrimidine synthase 0.91 PP_5104 thiazole synthase 0.92 1
Pseudomonas sp. S08-1 0.89 OH686_15885 phosphomethylpyrimidine synthase 0.88 OH686_14285 Thiazole synthase 0.77 50
Pseudomonas stutzeri RCH2 0.89 Psest_0477 thiamine biosynthesis protein ThiC 0.87 Psest_0267 Uncharacterized enzyme of thiazole biosynthesis 0.92 1
Marinobacter adhaerens HP15 0.80 HP15_453 thiamine biosynthesis protein thiC 0.72 HP15_3274 thiazole synthase — —
Herbaspirillum seropedicae SmR1 0.76 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.66 HSERO_RS02130 thiazole synthase 0.90 3
Dyella japonica UNC79MFTsu3.2 0.75 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.70 ABZR86_RS11645 thiazole synthase — —
Dechlorosoma suillum PS 0.75 Dsui_0422 thiamine biosynthesis protein ThiC 0.69 Dsui_1014 putative enzyme of thiazole biosynthesis — —
Paraburkholderia sabiae LMG 24235 0.75 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.35 QEN71_RS27930 thiazole synthase — —
Paraburkholderia graminis OAS925 0.75 ABIE53_002857 phosphomethylpyrimidine synthase 0.34 ABIE53_003714 thiazole synthase — —
Castellaniella sp019104865 MT123 0.75 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.67 ABCV34_RS14510 thiazole synthase — —
Burkholderia phytofirmans PsJN 0.75 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.34 BPHYT_RS17775 thiazole synthase — —
Lysobacter sp. OAE881 0.74 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.72 ABIE51_RS16545 thiazole synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.74 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.34 H281DRAFT_05639 thiazole-phosphate synthase — —
Rhodanobacter sp. FW510-T8 0.74 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.68 OKGIIK_11895 thiS thiazole synthase low > 52
Pontibacter actiniarum KMM 6156, DSM 19842 0.74 CA264_20435 phosphomethylpyrimidine synthase ThiC 0.40 CA264_20420 thiazole synthase 0.61 44
Acinetobacter radioresistens SK82 0.74 MPMX26_00180 Phosphomethylpyrimidine synthase 0.69 MPMX26_01107 Thiazole synthase low > 36
Pedobacter sp. GW460-11-11-14-LB5 0.73 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.38 CA265_RS20180 thiazole synthase low > 88
Xanthomonas campestris pv. campestris strain 8004 0.73 Xcc-8004.1066.1 hypothetical protein 0.70 Xcc-8004.1284.1 Thiazole biosynthesis protein ThiG 0.76 3
Mucilaginibacter yixingensis YX-36 DSM 26809 0.73 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.35 ABZR88_RS08825 thiazole synthase 0.93 1
Pectobacterium carotovorum WPP14 0.72 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.39 HER17_RS20400 thiazole synthase 0.92 9
Echinicola vietnamensis KMM 6221, DSM 17526 0.72 Echvi_3567 thiamine biosynthesis protein ThiC 0.39 Echvi_3564 Uncharacterized enzyme of thiazole biosynthesis low > 79
Ralstonia sp. UNC404CL21Col 0.72 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.37 ABZR87_RS04800 thiazole synthase — —
Dickeya dadantii 3937 0.72 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.38 DDA3937_RS01155 thiazole synthase 0.82 18
Ralstonia solanacearum PSI07 0.72 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.37 RPSI07_RS23435 thiazole synthase — —
Shewanella loihica PV-4 0.71 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.35 Shew_2092 thiazole biosynthesis family protein (RefSeq) low > 60
Ralstonia solanacearum IBSBF1503 0.71 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.36 RALBFv3_RS09925 thiazole synthase — —
Rahnella sp. WP5 0.71 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.38 EX31_RS16795 thiazole synthase low > 89
Ralstonia solanacearum UW163 0.71 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.36 UW163_RS03655 thiazole synthase — —
Kangiella aquimarina DSM 16071 0.71 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.37 B158DRAFT_0291 thiazole-phosphate synthase 0.95 3
Escherichia fergusonii Becca 0.71 EFB2_04617 Phosphomethylpyrimidine synthase 0.38 EFB2_04621 Thiazole synthase low > 86
Escherichia coli ECRC62 0.71 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.38 BNILDI_05985 thiG thiazole synthase low > 75
Cupriavidus basilensis FW507-4G11 0.71 RR42_RS01290 thiamine biosynthesis protein ThiC 0.36 RR42_RS01305 thiazole synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.71 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.38 OHPLBJKB_04060 Thiazole synthase low > 73
Escherichia coli BW25113 0.71 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.38 b3991 thiG thiamin biosynthesis, thiazole moiety (VIMSS) 0.94 2
Escherichia coli ECRC99 0.71 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.38 KEDOAH_14765 thiG thiazole synthase — —
Escherichia coli ECRC98 0.71 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.38 JDDGAC_17020 thiG thiazole synthase low > 86
Escherichia coli ECRC100 0.71 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.38 OKFHMN_13395 thiG thiazole synthase low > 80
Escherichia coli ECOR27 0.71 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.38 NOLOHH_05540 thiG thiazole synthase 0.91 5
Escherichia coli ECRC102 0.71 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.38 NIAGMN_11145 thiG thiazole synthase — —
Escherichia coli Nissle 1917 0.71 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.37 ECOLIN_RS23020 thiazole synthase 0.52 55
Escherichia coli ECRC101 0.71 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.38 MCAODC_03895 thiG thiazole synthase 0.90 8
Ralstonia solanacearum GMI1000 0.71 RS_RS00555 phosphomethylpyrimidine synthase 0.37 RS_RS00535 thiazole synthase — —
Enterobacter asburiae PDN3 0.71 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.36 EX28DRAFT_4532 Uncharacterized enzyme of thiazole biosynthesis low > 76
Shewanella amazonensis SB2B 0.71 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.38 Sama_1856 thiG thiazole synthase (RefSeq) low > 62
Pantoea sp. MT58 0.71 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.32 IAI47_20700 thiazole synthase 0.34 44
Escherichia coli BL21 0.71 ECD_03871 phosphomethylpyrimidine synthase 0.38 ECD_03867 thiamine biosynthesis ThiGH complex subunit low > 61
Escherichia coli ECOR38 0.71 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.38 HEPCGN_12030 thiG thiazole synthase 0.86 28
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.71 GFF4198 Thiamin biosynthesis protein ThiC 0.38 GFF4202 Thiazole biosynthesis protein ThiG low > 78
Enterobacter sp. TBS_079 0.70 MPMX20_00217 Phosphomethylpyrimidine synthase 0.36 MPMX20_00213 Thiazole synthase low > 85
Dickeya dianthicola 67-19 0.70 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.37 HGI48_RS01150 thiazole synthase 0.84 21
Serratia liquefaciens MT49 0.70 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.37 IAI46_01300 thiazole synthase low > 86
Klebsiella michiganensis M5al 0.70 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.37 BWI76_RS01535 thiazole synthase 0.71 3
Dickeya dianthicola ME23 0.70 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.38 DZA65_RS01195 thiazole synthase 0.89 4
Erwinia tracheiphila SCR3 0.70 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.36 LU632_RS00950 thiazole synthase low > 74
Vibrio cholerae E7946 ATCC 55056 0.69 CSW01_00335 phosphomethylpyrimidine synthase 0.39 CSW01_00355 thiazole synthase low > 62
Shewanella oneidensis MR-1 0.69 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.36 SO2441 thiG thiG protein (NCBI ptt file) 0.50 3
Shewanella sp. ANA-3 0.69 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.37 Shewana3_1940 thiG thiazole synthase (RefSeq) low > 73
Alteromonas macleodii MIT1002 0.68 MIT1002_00097 Phosphomethylpyrimidine synthase 0.37 MIT1002_00093 Thiazole synthase 0.99 2
Variovorax sp. SCN45 0.67 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.35 GFF1188 Thiazole synthase (EC 2.8.1.10) 0.85 4
Hydrogenophaga sp. GW460-11-11-14-LB1 0.67 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.34 GFF246 Thiazole biosynthesis protein ThiG — —
Acidovorax sp. GW101-3H11 0.66 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.32 Ac3H11_1059 Thiazole biosynthesis protein ThiG — —
Variovorax sp. OAS795 0.66 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.36 ABID97_RS15315 thiazole synthase low > 91
Azospirillum brasilense Sp245 0.65 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.41 AZOBR_RS30960 thiazole synthase — —
Phaeobacter inhibens DSM 17395 0.64 PGA1_c09110 thiamine biosynthesis protein ThiC 0.33 PGA1_c09070 thiazole biosynthesis protein ThiG 0.94 1
Caulobacter crescentus NA1000 Δfur 0.64 CCNA_02109 thiamine biosynthesis protein thiC 0.58 CCNA_01957 thiazole biosynthesis protein ThiG — —
Agrobacterium fabrum C58 0.64 Atu2569 thiamine biosynthesis protein 0.33 Atu2566 thiamin biosynthesis ThiG low > 89
Caulobacter crescentus NA1000 0.64 CCNA_02109 thiamine biosynthesis protein thiC 0.58 CCNA_01957 thiazole biosynthesis protein ThiG — —
Rhodopseudomonas palustris CGA009 0.64 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.33 TX73_018530 thiazole synthase — —
Dinoroseobacter shibae DFL-12 0.63 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.29 Dshi_0912 thiazole biosynthesis family protein (RefSeq) — —
Sinorhizobium meliloti 1021 0.63 SM_b20615 thiamine biosynthesis protein ThiC 0.29 SM_b20617 thiazole synthase — —
Bosea sp. OAE506 0.63 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.31 ABIE41_RS20185 thiazole synthase — —
Azospirillum sp. SherDot2 0.63 MPMX19_00336 Phosphomethylpyrimidine synthase 0.44 MPMX19_00262 Thiazole synthase low > 112
Brevundimonas sp. GW460-12-10-14-LB2 0.62 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.54 A4249_RS07975 thiazole synthase — —
Phocaeicola vulgatus CL09T03C04 0.57 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.37 HMPREF1058_RS03285 thiazole synthase 0.91 4
Phocaeicola dorei CL03T12C01 0.57 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.37 ABI39_RS17755 thiazole synthase 0.83 6
Bacteroides ovatus ATCC 8483 0.57 BACOVA_02358 thiamine biosynthesis protein ThiC 0.37 BACOVA_02359 thiazole biosynthesis protein ThiG 0.85 7
Bacteroides thetaiotaomicron VPI-5482 0.56 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.37 BT0651 thiamine biosynthesis protein ThiG (NCBI ptt file) 0.49 7
Bacteroides stercoris CC31F 0.56 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.35 HMPREF1181_RS14680 thiazole synthase low > 56
Mycobacterium tuberculosis H37Rv 0.52 Rv0423c Probable thiamine biosynthesis protein ThiC 0.44 Rv0417 Probable thiamin biosynthesis protein ThiG (thiazole biosynthesis protein) — —

Not shown: 4 genomes with orthologs for PFLU_RS02430 only; 5 genomes with orthologs for PFLU_RS28420 only