Conservation of cofitness between NOLOHH_05820 and NOLOHH_05730 in Escherichia coli ECOR27

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_05820 metB cystathionine gamma-synthase 1.0 NOLOHH_05730 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.94 20
Escherichia coli ECRC62 1.00 BNILDI_05715 metB cystathionine gamma-synthase 1.00 BNILDI_05795 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.95 42
Escherichia coli BW25113 1.00 b3939 metB cystathionine gamma-synthase (NCBI) 1.00 b3958 argC N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) 0.86 33
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04111 Cystathionine gamma-synthase 1.00 OHPLBJKB_04092 N-acetyl-gamma-glutamyl-phosphate reductase low > 73
Escherichia coli BL21 1.00 ECD_03825 cystathionine gamma-synthase, PLP-dependent 1.00 ECD_03843 N-acetyl-gamma-glutamylphosphate reductase, NAD(P)-binding 0.82 32
Escherichia coli ECOR38 0.99 HEPCGN_12345 metB cystathionine gamma-synthase 0.99 HEPCGN_12230 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.93 36
Escherichia fergusonii Becca 0.99 EFB2_04679 Cystathionine gamma-synthase 0.99 EFB2_04656 N-acetyl-gamma-glutamyl-phosphate reductase low > 86
Escherichia coli ECRC101 0.99 MCAODC_04175 metB cystathionine gamma-synthase 0.99 MCAODC_04085 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.91 21
Escherichia coli Nissle 1917 0.99 ECOLIN_RS22725 cystathionine gamma-synthase 0.99 ECOLIN_RS22845 N-acetyl-gamma-glutamyl-phosphate reductase 0.84 27
Escherichia coli ECRC99 0.99 KEDOAH_14485 metB cystathionine gamma-synthase 0.99 KEDOAH_14575 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Escherichia coli ECRC102 0.99 NIAGMN_11430 metB cystathionine gamma-synthase 0.99 NIAGMN_11335 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Escherichia coli ECRC98 0.99 JDDGAC_17300 metB cystathionine gamma-synthase 0.99 JDDGAC_17210 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.83 50
Escherichia coli ECRC100 0.99 OKFHMN_13675 metB cystathionine gamma-synthase 0.99 OKFHMN_13585 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.98 23
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) 0.92 GFF2344 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 78
Klebsiella michiganensis M5al 0.96 BWI76_RS00785 cystathionine gamma-synthase 0.91 BWI76_RS00845 N-acetyl-gamma-glutamyl-phosphate reductase 0.90 20
Enterobacter asburiae PDN3 0.96 EX28DRAFT_4411 cystathionine gamma-synthase (EC 2.5.1.48) 0.90 EX28DRAFT_4420 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) 0.67 49
Enterobacter sp. TBS_079 0.95 MPMX20_04531 Cystathionine gamma-synthase 0.89 MPMX20_04522 N-acetyl-gamma-glutamyl-phosphate reductase 0.91 26
Pectobacterium carotovorum WPP14 0.87 HER17_RS00910 cystathionine gamma-synthase 0.79 HER17_RS20630 N-acetyl-gamma-glutamyl-phosphate reductase low > 75
Dickeya dianthicola 67-19 0.87 HGI48_RS20425 cystathionine gamma-synthase 0.79 HGI48_RS00875 N-acetyl-gamma-glutamyl-phosphate reductase 0.77 63
Dickeya dianthicola ME23 0.87 DZA65_RS21470 cystathionine gamma-synthase 0.78 DZA65_RS00935 N-acetyl-gamma-glutamyl-phosphate reductase 0.85 28
Erwinia tracheiphila SCR3 0.87 LU632_RS19640 metB cystathionine gamma-synthase 0.78 LU632_RS19615 argC N-acetyl-gamma-glutamyl-phosphate reductase low > 74
Dickeya dadantii 3937 0.87 DDA3937_RS00950 cystathionine gamma-synthase 0.78 DDA3937_RS20350 N-acetyl-gamma-glutamyl-phosphate reductase 0.87 30
Serratia liquefaciens MT49 0.83 IAI46_24540 cystathionine gamma-synthase 0.82 IAI46_24515 N-acetyl-gamma-glutamyl-phosphate reductase low > 86
Pantoea sp. MT58 0.82 IAI47_00880 cystathionine gamma-synthase 0.78 IAI47_00905 N-acetyl-gamma-glutamyl-phosphate reductase 0.78 73
Rahnella sp. WP5 0.78 EX31_RS14215 cystathionine gamma-synthase 0.79 EX31_RS14190 N-acetyl-gamma-glutamyl-phosphate reductase 0.98 7
Kangiella aquimarina DSM 16071 0.60 B158DRAFT_2459 cystathionine gamma-synthase (EC 2.5.1.48) 0.18 B158DRAFT_1979 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 40
Shewanella loihica PV-4 0.60 Shew_0520 O-succinylhomoserine (thiol)-lyase (RefSeq) 0.44 Shew_0202 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.98 8
Shewanella amazonensis SB2B 0.60 Sama_3171 cystathionine gamma-synthase (RefSeq) 0.44 Sama_0256 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.96 21
Shewanella sp. ANA-3 0.60 Shewana3_3614 cystathionine gamma-synthase (RefSeq) 0.45 Shewana3_3905 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.88 56
Vibrio cholerae E7946 ATCC 55056 0.60 CSW01_13550 O-succinylhomoserine (thiol)-lyase 0.63 CSW01_13380 N-acetyl-gamma-glutamyl-phosphate reductase low > 62
Shewanella oneidensis MR-1 0.59 SO4056 metB cystathionine gamma-synthase (NCBI ptt file) 0.44 SO0275 argC N-acetyl-gamma-glutamyl-phosphate reductase (NCBI ptt file) 0.93 37
Lysobacter sp. OAE881 0.57 ABIE51_RS16185 O-succinylhomoserine (thiol)-lyase 0.20 ABIE51_RS13385 N-acetyl-gamma-glutamyl-phosphate reductase 0.98 8
Xanthomonas campestris pv. campestris strain 8004 0.56 Xcc-8004.1596.1 hypothetical protein 0.17 Xcc-8004.2322.1 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) 0.66 40
Rhodanobacter denitrificans MT42 0.55 LRK55_RS05085 cystathionine gamma-synthase 0.17 LRK55_RS02140 N-acetyl-gamma-glutamyl-phosphate reductase low > 63
Rhodanobacter denitrificans FW104-10B01 0.55 LRK54_RS05305 cystathionine gamma-synthase 0.17 LRK54_RS02385 N-acetyl-gamma-glutamyl-phosphate reductase 0.69 13
Dyella japonica UNC79MFTsu3.2 0.54 ABZR86_RS19030 cystathionine gamma-synthase 0.18 ABZR86_RS08700 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.92 47
Rhodanobacter sp. FW510-T8 0.53 OKGIIK_01515 metB cystathionine gamma-synthase 0.17 OKGIIK_09435 argC N-acetyl-gamma-glutamyl-phosphate reductase low > 52
Pseudomonas fluorescens FW300-N2E3 0.41 AO353_23295 cystathionine beta-lyase 0.31 AO353_07155 N-acetyl-gamma-glutamyl-phosphate reductase low > 101
Pontibacter actiniarum KMM 6156, DSM 19842 0.41 CA264_20315 cystathionine gamma-synthase 0.20 CA264_06250 N-acetyl-gamma-glutamyl-phosphate reductase low > 74
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1) 0.31 Pf1N1B4_2559 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Pseudomonas fluorescens SBW25-INTG 0.39 PFLU_RS16625 cystathionine gamma-synthase 0.32 PFLU_RS27315 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas fluorescens SBW25 0.39 PFLU_RS16625 cystathionine gamma-synthase 0.32 PFLU_RS27315 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pedobacter sp. GW460-11-11-14-LB5 0.38 CA265_RS06375 cystathionine gamma-synthase 0.21 CA265_RS18540 N-succinylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.51 58
Mucilaginibacter yixingensis YX-36 DSM 26809 0.38 ABZR88_RS06685 cystathionine gamma-synthase 0.21 ABZR88_RS15505 N-acetyl-gamma-glutamyl-phosphate reductase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_2080 Cystathionine beta-lyases/cystathionine gamma-synthases 0.20 Echvi_3847 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) low > 79
Mycobacterium tuberculosis H37Rv 0.38 Rv1079 Cystathionine gamma-synthase MetB (CGS) (O-succinylhomoserine [thiol]-lyase) 0.21 Rv1652 Probable N-acetyl-gamma-glutamyl-phoshate reductase ArgC — —
Rhodospirillum rubrum S1H 0.37 Rru_A0786 Cystathionine gamma-synthase (NCBI) 0.31 Rru_A2421 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) low > 58
Pseudomonas putida KT2440 0.36 PP_4594 putative Cystathionine gamma-synthase 0.32 PP_0432 N-acetyl-gamma-glutamyl-phosphate reductase 1 low > 96
Bifidobacterium breve UCC2003 0.34 BBR_RS13145 cystathionine gamma-synthase 0.17 BBR_RS13885 N-acetyl-gamma-glutamyl-phosphate reductase low > 34
Pseudomonas simiae WCS417 0.34 PS417_11735 methionine gamma-lyase 0.31 PS417_25660 N-acetyl-gamma-glutamyl-phosphate reductase — —
Castellaniella sp019104865 MT123 0.33 ABCV34_RS15785 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.30 ABCV34_RS10590 N-acetyl-gamma-glutamyl-phosphate reductase — —
Phaeobacter inhibens DSM 17395 0.33 PGA1_c16600 methionine gamma-lyase MdeA 0.23 PGA1_c17050 N-acetyl-gamma-glutamyl-phosphate reductase ArgC low > 62
Acinetobacter radioresistens SK82 0.32 MPMX26_01645 O-succinylhomoserine sulfhydrylase 0.29 MPMX26_01281 N-acetyl-gamma-glutamyl-phosphate reductase 0.87 27
Azospirillum sp. SherDot2 0.32 MPMX19_06514 L-methionine gamma-lyase 0.27 MPMX19_03843 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas stutzeri RCH2 0.31 Psest_2578 O-succinylhomoserine sulfhydrylase 0.29 Psest_3639 N-acetyl-gamma-glutamyl-phosphate reductase, common form — —
Pseudomonas sp. RS175 0.31 PFR28_02810 O-succinylhomoserine sulfhydrylase 0.30 PFR28_04033 N-acetyl-gamma-glutamyl-phosphate reductase low > 88
Pseudomonas syringae pv. syringae B728a ΔmexB 0.31 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.30 Psyr_4569 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas syringae pv. syringae B728a 0.31 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.30 Psyr_4569 N-acetyl-gamma-glutamyl-phosphate reductase — —
Acidovorax sp. GW101-3H11 0.31 Ac3H11_34 Methionine gamma-lyase (EC 4.4.1.11) 0.11 Ac3H11_2950 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 79
Pseudomonas fluorescens FW300-N2E2 0.31 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.31 Pf6N2E2_4836 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 103
Pseudomonas fluorescens FW300-N2C3 0.31 AO356_21470 O-succinylhomoserine sulfhydrylase 0.31 AO356_14490 N-acetyl-gamma-glutamyl-phosphate reductase low > 104
Pseudomonas fluorescens GW456-L13 0.31 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.31 PfGW456L13_1233 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) 0.82 48
Magnetospirillum magneticum AMB-1 0.30 AMB_RS21365 O-succinylhomoserine sulfhydrylase 0.30 AMB_RS09075 N-acetyl-gamma-glutamyl-phosphate reductase — —
Pseudomonas sp. S08-1 0.30 OH686_04415 O-succinylhomoserine sulfhydrylase 0.31 OH686_15195 N-acetyl-gamma-glutamyl-phosphate reductase 0.59 49
Ralstonia sp. UNC404CL21Col 0.29 ABZR87_RS13810 O-acetylhomoserine aminocarboxypropyltransferase 0.14 ABZR87_RS05600 N-acetyl-gamma-glutamyl-phosphate reductase low > 80
Marinobacter adhaerens HP15 0.29 HP15_1820 methionine gamma-lyase 0.29 HP15_352 N-acetyl-gamma-glutamyl-phosphate reductase 0.88 18
Cupriavidus basilensis FW507-4G11 0.29 RR42_RS14320 O-succinylhomoserine sulfhydrylase 0.13 RR42_RS01210 n-acetyl-gamma-glutamyl-phosphate reductase low > 128
Variovorax sp. SCN45 0.28 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.13 GFF4146 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) — —
Dinoroseobacter shibae DFL-12 0.28 Dshi_1002 Cystathionine gamma-synthase (RefSeq) 0.24 Dshi_1759 N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) — —
Ralstonia solanacearum UW163 0.28 UW163_RS15180 O-acetylhomoserine aminocarboxypropyltransferase 0.14 UW163_RS03490 N-acetyl-gamma-glutamyl-phosphate reductase — —
Ralstonia solanacearum IBSBF1503 0.28 RALBFv3_RS01870 O-acetylhomoserine aminocarboxypropyltransferase 0.14 RALBFv3_RS10090 N-acetyl-gamma-glutamyl-phosphate reductase low > 76
Variovorax sp. OAS795 0.28 ABID97_RS21630 O-succinylhomoserine sulfhydrylase 0.09 ABID97_RS02250 N-acetyl-gamma-glutamyl-phosphate reductase — —
Azospirillum brasilense Sp245 0.28 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase 0.26 AZOBR_RS07795 N-acetyl-gamma-glutamyl-phosphate reductase — —
Ralstonia solanacearum GMI1000 0.27 RS_RS07865 O-acetylhomoserine aminocarboxypropyltransferase 0.14 RS_RS00700 N-acetyl-gamma-glutamyl-phosphate reductase — —
Ralstonia solanacearum PSI07 0.27 RPSI07_RS15620 O-acetylhomoserine aminocarboxypropyltransferase 0.14 RPSI07_RS23280 N-acetyl-gamma-glutamyl-phosphate reductase low > 81
Sphingomonas koreensis DSMZ 15582 0.27 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) 0.10 Ga0059261_0351 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.90 23
Bosea sp. OAE506 0.26 ABIE41_RS03970 O-succinylhomoserine sulfhydrylase 0.18 ABIE41_RS15755 N-acetyl-gamma-glutamyl-phosphate reductase low > 77
Phocaeicola vulgatus CL09T03C04 0.24 HMPREF1058_RS17635 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 0.20 HMPREF1058_RS08840 N-acetyl-gamma-glutamyl-phosphate reductase low > 67
Phocaeicola dorei CL03T12C01 0.23 ABI39_RS13825 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 0.20 ABI39_RS02970 N-acetyl-gamma-glutamyl-phosphate reductase low > 72
Bacteroides thetaiotaomicron VPI-5482 0.23 BT2387 O-acetylhomoserine (thiol)-lyase (NCBI ptt file) 0.21 BT3759 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) low > 81
Parabacteroides merdae CL09T00C40 0.23 HMPREF1078_RS07330 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 0.20 HMPREF1078_RS10580 N-acetyl-gamma-glutamyl-phosphate reductase low > 61
Bacteroides ovatus ATCC 8483 0.23 BACOVA_03030 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 0.21 BACOVA_03589 N-acetyl-gamma-glutamyl-phosphate reductase low > 94
Synechococcus elongatus PCC 7942 0.23 Synpcc7942_0370 metY O-acetylhomoserine/O-acetylserine sulfhydrylase 0.26 Synpcc7942_1433 argC N-acetyl-gamma-glutamyl-phosphate reductase — —
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS05290 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 0.21 HMPREF1181_RS03450 N-acetyl-gamma-glutamyl-phosphate reductase low > 56
Herbaspirillum seropedicae SmR1 0.22 HSERO_RS18310 O-acetylhomoserine aminocarboxypropyltransferase 0.30 HSERO_RS19210 N-acetyl-gamma-glutamyl-phosphate reductase low > 78
Alteromonas macleodii MIT1002 0.21 MIT1002_02266 Methionine gamma-lyase 0.47 MIT1002_00471 N-acetyl-gamma-glutamyl-phosphate reductase 0.98 24

Not shown: 14 genomes with orthologs for NOLOHH_05820 only; 4 genomes with orthologs for NOLOHH_05730 only