Conservation of cofitness between HEPCGN_08095 and HEPCGN_08700 in Escherichia coli ECOR38

86 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_08095 rnhB ribonuclease HII 1.0 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.51 15
Escherichia coli ECRC102 1.00 NIAGMN_07990 rnhB ribonuclease HII 1.00 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC99 1.00 KEDOAH_18015 rnhB ribonuclease HII 1.00 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC101 1.00 MCAODC_00655 rnhB ribonuclease HII 1.00 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase low > 87
Escherichia coli ECRC100 1.00 OKFHMN_10140 rnhB ribonuclease HII 1.00 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase low > 80
Escherichia coli ECRC98 1.00 JDDGAC_13735 rnhB ribonuclease HII 1.00 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase low > 86
Escherichia fergusonii Becca 1.00 EFB2_03861 Ribonuclease HII 1.00 EFB2_03972 3-isopropylmalate dehydrogenase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS00995 ribonuclease HII 1.00 ECOLIN_RS00395 3-isopropylmalate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_03480 Ribonuclease HII 1.00 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 73
Escherichia coli ECOR27 0.99 NOLOHH_02485 rnhB ribonuclease HII 1.00 NOLOHH_03065 leuA 2-isopropylmalate synthase low > 75
Escherichia coli BW25113 0.99 b0183 rnhB ribonuclease HII (NCBI) 1.00 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) low > 76
Escherichia coli ECRC62 0.99 BNILDI_09185 rnhB ribonuclease HII 1.00 BNILDI_08545 leuA 2-isopropylmalate synthase low > 75
Escherichia coli BL21 0.98 ECD_00181 ribonuclease HII 1.00 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent low > 61
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF39 Ribonuclease HII (EC 3.1.26.4) 0.95 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 78
Enterobacter sp. TBS_079 0.92 MPMX20_00867 Ribonuclease HII 0.94 MPMX20_00768 3-isopropylmalate dehydrogenase low > 85
Enterobacter asburiae PDN3 0.91 EX28DRAFT_3771 RNase HII (EC 3.1.26.4) 0.94 EX28DRAFT_3669 3-isopropylmalate dehydrogenase low > 76
Klebsiella michiganensis M5al 0.87 BWI76_RS05285 ribonuclease HII 0.93 BWI76_RS04675 3-isopropylmalate dehydrogenase — —
Serratia liquefaciens MT49 0.83 IAI46_20190 ribonuclease HII 0.86 IAI46_03350 3-isopropylmalate dehydrogenase low > 86
Pantoea sp. MT58 0.81 IAI47_15460 ribonuclease HII 0.83 IAI47_16005 3-isopropylmalate dehydrogenase low > 76
Dickeya dadantii 3937 0.80 DDA3937_RS05185 ribonuclease HII 0.88 DDA3937_RS18120 3-isopropylmalate dehydrogenase low > 74
Pectobacterium carotovorum WPP14 0.80 HER17_RS16265 ribonuclease HII 0.88 HER17_RS03080 3-isopropylmalate dehydrogenase low > 75
Rahnella sp. WP5 0.79 EX31_RS12965 ribonuclease HII 0.88 EX31_RS03685 3-isopropylmalate dehydrogenase low > 89
Dickeya dianthicola ME23 0.79 DZA65_RS05525 ribonuclease HII 0.88 DZA65_RS19205 3-isopropylmalate dehydrogenase — —
Dickeya dianthicola 67-19 0.79 HGI48_RS05185 ribonuclease HII 0.88 HGI48_RS18060 3-isopropylmalate dehydrogenase — —
Erwinia tracheiphila SCR3 0.76 LU632_RS19895 rnhB ribonuclease HII 0.83 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase — —
Vibrio cholerae E7946 ATCC 55056 0.69 CSW01_11440 ribonuclease HII 0.77 CSW01_12600 3-isopropylmalate dehydrogenase low > 62
Pseudomonas fluorescens SBW25-INTG 0.67 PFLU_RS06345 ribonuclease HII 0.53 PFLU_RS20565 3-isopropylmalate dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.67 PFLU_RS06345 ribonuclease HII 0.53 PFLU_RS20565 3-isopropylmalate dehydrogenase low > 109
Pseudomonas fluorescens FW300-N2E3 0.67 AO353_16530 ribonuclease HII 0.53 AO353_20635 3-isopropylmalate dehydrogenase low > 101
Pseudomonas fluorescens GW456-L13 0.66 PfGW456L13_4694 Ribonuclease HII (EC 3.1.26.4) 0.52 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) — —
Pseudomonas simiae WCS417 0.66 PS417_06280 ribonuclease HII 0.53 PS417_18585 3-isopropylmalate dehydrogenase low > 88
Pseudomonas fluorescens FW300-N1B4 0.65 Pf1N1B4_3098 Ribonuclease HII (EC 3.1.26.4) 0.53 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 87
Pseudomonas fluorescens FW300-N2C3 0.65 AO356_05970 ribonuclease HII 0.52 AO356_21415 3-isopropylmalate dehydrogenase low > 104
Pseudomonas fluorescens FW300-N2E2 0.65 Pf6N2E2_3055 Ribonuclease HII (EC 3.1.26.4) 0.52 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 103
Pseudomonas putida KT2440 0.65 PP_1605 Ribonuclease HII 0.53 PP_1988 3-isopropylmalate dehydrogenase low > 96
Pseudomonas sp. RS175 0.65 PFR28_00410 Ribonuclease HII 0.52 PFR28_02821 3-isopropylmalate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.64 Psyr_1357 RNase HII 0.52 Psyr_1985 3-isopropylmalate dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a 0.64 Psyr_1357 RNase HII 0.52 Psyr_1985 3-isopropylmalate dehydrogenase low > 86
Pseudomonas stutzeri RCH2 0.63 Psest_2828 Ribonuclease HII 0.50 Psest_2589 3-isopropylmalate dehydrogenase — —
Pseudomonas sp. S08-1 0.63 OH686_06415 Ribonuclease HII 0.50 OH686_04470 3-isopropylmalate dehydrogenase — —
Shewanella sp. ANA-3 0.60 Shewana3_2801 rnhB ribonuclease HII (RefSeq) 0.70 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.53 47
Dechlorosoma suillum PS 0.60 Dsui_2680 ribonuclease HII 0.51 Dsui_3198 3-isopropylmalate dehydrogenase — —
Marinobacter adhaerens HP15 0.60 HP15_1180 ribonuclease HII 0.51 HP15_1832 3-isopropylmalate dehydrogenase low > 73
Alteromonas macleodii MIT1002 0.60 MIT1002_01017 Ribonuclease HII 0.64 MIT1002_00948 3-isopropylmalate dehydrogenase low > 70
Shewanella oneidensis MR-1 0.59 SO1643 rnhB ribonuclease HII (NCBI ptt file) 0.70 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.59 Sama_1153 rnhB ribonuclease HII (RefSeq) 0.68 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) low > 62
Kangiella aquimarina DSM 16071 0.59 B158DRAFT_1094 RNase HII (EC 3.1.26.4) 0.49 B158DRAFT_1322 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 40
Shewanella loihica PV-4 0.59 Shew_2621 ribonuclease H (RefSeq) 0.68 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.34 28
Herbaspirillum seropedicae SmR1 0.54 HSERO_RS10945 ribonuclease HII 0.47 HSERO_RS16500 3-isopropylmalate dehydrogenase low > 78
Cupriavidus basilensis FW507-4G11 0.54 RR42_RS11805 ribonuclease HII 0.47 RR42_RS14385 3-isopropylmalate dehydrogenase low > 128
Acinetobacter radioresistens SK82 0.53 MPMX26_01083 Ribonuclease HII 0.50 MPMX26_00348 3-isopropylmalate dehydrogenase low > 36
Ralstonia sp. UNC404CL21Col 0.53 ABZR87_RS11895 ribonuclease HII 0.47 ABZR87_RS14530 3-isopropylmalate dehydrogenase low > 80
Castellaniella sp019104865 MT123 0.52 ABCV34_RS04040 ribonuclease HII 0.47 ABCV34_RS04280 3-isopropylmalate dehydrogenase low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.52 GFF4901 Ribonuclease HII (EC 3.1.26.4) 0.49 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 90
Acidovorax sp. GW101-3H11 0.51 Ac3H11_432 Ribonuclease HII (EC 3.1.26.4) 0.50 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 79
Rhodanobacter sp. FW510-T8 0.50 OKGIIK_10205 rnhB ribonuclease HII 0.39 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase low > 52
Variovorax sp. SCN45 0.49 GFF379 Ribonuclease HII (EC 3.1.26.4) 0.50 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 127
Dyella japonica UNC79MFTsu3.2 0.48 ABZR86_RS21650 ribonuclease HII 0.38 ABZR86_RS15950 3-isopropylmalate dehydrogenase low > 74
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS03320 ribonuclease HII 0.39 LRK54_RS10325 3-isopropylmalate dehydrogenase low > 59
Caulobacter crescentus NA1000 0.45 CCNA_00383 ribonuclease HII 0.42 CCNA_00193 3-isopropylmalate dehydrogenase low > 66
Rhodanobacter denitrificans MT42 0.45 LRK55_RS03070 ribonuclease HII 0.39 LRK55_RS09965 3-isopropylmalate dehydrogenase low > 63
Caulobacter crescentus NA1000 Δfur 0.45 CCNA_00383 ribonuclease HII 0.42 CCNA_00193 3-isopropylmalate dehydrogenase low > 67
Xanthomonas campestris pv. campestris strain 8004 0.45 Xcc-8004.3570.1 Ribonuclease HII (EC 3.1.26.4) 0.48 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 74
Phaeobacter inhibens DSM 17395 0.43 PGA1_c33580 ribonuclease HII 0.48 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB low > 62
Sphingomonas koreensis DSMZ 15582 0.43 Ga0059261_1962 RNase HII (EC 3.1.26.4) 0.46 Ga0059261_3190 3-isopropylmalate dehydrogenase low > 68
Brevundimonas sp. GW460-12-10-14-LB2 0.42 A4249_RS09510 ribonuclease HII 0.41 A4249_RS09995 3-isopropylmalate dehydrogenase low > 48
Bacteroides thetaiotaomicron VPI-5482 0.42 BT3412 ribonuclease HII (NCBI ptt file) 0.42 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) low > 81
Pontibacter actiniarum KMM 6156, DSM 19842 0.42 CA264_00195 ribonuclease HII 0.43 CA264_09445 3-isopropylmalate dehydrogenase low > 74
Bacteroides ovatus ATCC 8483 0.41 BACOVA_01892 ribonuclease HII 0.42 BACOVA_04600 3-isopropylmalate dehydrogenase low > 94
Parabacteroides merdae CL09T00C40 0.41 HMPREF1078_RS11835 ribonuclease HII 0.41 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase low > 61
Bacteroides stercoris CC31F 0.41 HMPREF1181_RS02630 ribonuclease HII 0.41 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase low > 56
Lysobacter sp. OAE881 0.40 ABIE51_RS06875 ribonuclease HII 0.42 ABIE51_RS17585 3-isopropylmalate dehydrogenase low > 62
Phocaeicola vulgatus CL09T03C04 0.40 HMPREF1058_RS12265 ribonuclease HII 0.43 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase low > 67
Pedobacter sp. GW460-11-11-14-LB5 0.40 CA265_RS23950 ribonuclease HII 0.42 CA265_RS15850 3-isopropylmalate dehydrogenase low > 88
Agrobacterium fabrum C58 0.40 Atu0720 ribonuclease HII 0.45 Atu2791 3-isopropylmalate dehydrogenase low > 89
Phocaeicola dorei CL03T12C01 0.40 ABI39_RS04525 ribonuclease HII 0.42 ABI39_RS10215 3-isopropylmalate dehydrogenase low > 72
Magnetospirillum magneticum AMB-1 0.40 AMB_RS20190 ribonuclease HII 0.45 AMB_RS20570 3-isopropylmalate dehydrogenase — —
Azospirillum sp. SherDot2 0.39 MPMX19_05650 Ribonuclease HII 0.47 MPMX19_00607 3-isopropylmalate dehydrogenase low > 112
Rhodospirillum rubrum S1H 0.38 Rru_A3209 Ribonuclease H (NCBI) 0.42 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) — —
Sinorhizobium meliloti 1021 0.38 SMc00867 ribonuclease HII 0.43 SMc04405 3-isopropylmalate dehydrogenase — —
Desulfovibrio vulgaris Hildenborough JW710 0.37 DVU0834 rnhB ribonuclease HII (TIGR) 0.53 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) low > 55
Dinoroseobacter shibae DFL-12 0.37 Dshi_0023 Ribonuclease H (RefSeq) 0.45 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) — —
Azospirillum brasilense Sp245 0.37 AZOBR_RS20300 ribonuclease HII 0.45 AZOBR_RS14130 3-isopropylmalate dehydrogenase low > 97
Echinicola vietnamensis KMM 6221, DSM 17526 0.37 Echvi_2417 Ribonuclease HII 0.43 Echvi_2062 3-isopropylmalate dehydrogenase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.37 ABZR88_RS22230 ribonuclease HII 0.42 ABZR88_RS11605 3-isopropylmalate dehydrogenase — —
Synechococcus elongatus PCC 7942 0.35 Synpcc7942_0879 rhnB RNase HII 0.46 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase — —
Bosea sp. OAE506 0.34 ABIE41_RS22855 ribonuclease HII 0.43 ABIE41_RS11860 3-isopropylmalate dehydrogenase — —

Not shown: 2 genomes with orthologs for HEPCGN_08095 only; 12 genomes with orthologs for HEPCGN_08700 only