Conservation of cofitness between PS417_23915 and PS417_24600 in Pseudomonas simiae WCS417

89 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas simiae WCS417 1.0 PS417_23915 pantoate--beta-alanine ligase 1.0 PS417_24600 hydrogenase 0.61 3
Pseudomonas fluorescens SBW25-INTG 0.98 PFLU_RS25755 pantoate--beta-alanine ligase 0.98 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas fluorescens SBW25 0.98 PFLU_RS25755 pantoate--beta-alanine ligase 0.98 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas fluorescens FW300-N1B4 0.85 Pf1N1B4_2853 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.80 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas fluorescens FW300-N2E2 0.84 Pf6N2E2_5152 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.79 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Pseudomonas sp. RS175 0.84 PFR28_03722 Pantothenate synthetase 0.86 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Pseudomonas fluorescens GW456-L13 0.84 PfGW456L13_1520 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.89 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas fluorescens FW300-N2C3 0.84 AO356_16055 pantoate--beta-alanine ligase 0.89 AO356_15435 hydrogenase — —
Pseudomonas fluorescens FW300-N2E3 0.84 AO353_14380 pantoate--beta-alanine ligase 0.90 AO353_06350 hydrogenase low > 101
Pseudomonas putida KT2440 0.80 PP_4700 pantothenate synthetase 0.83 PP_4782 Phosphomethylpyrimidine kinase low > 96
Pseudomonas syringae pv. syringae B728a ΔmexB 0.78 Psyr_0827 pantothenate synthetase 0.84 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas syringae pv. syringae B728a 0.78 Psyr_0827 pantothenate synthetase 0.84 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas sp. S08-1 0.72 OH686_17240 pantoate--beta-alanine ligase 0.81 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD — —
Pseudomonas stutzeri RCH2 0.69 Psest_0995 pantoate--beta-alanine ligase 0.77 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Marinobacter adhaerens HP15 0.62 HP15_323 pantothenate synthetase 0.26 HP15_349 phosphomethylpyrimidine kinase — —
Escherichia fergusonii Becca 0.50 EFB2_03911 Pantothenate synthetase 0.24 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 86
Escherichia coli ECRC101 0.50 MCAODC_00920 panC pantoate--beta-alanine ligase 0.24 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli BW25113 0.50 b0133 panC pantoate--beta-alanine ligase (NCBI) 0.24 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.38 25
Escherichia coli ECRC99 0.50 KEDOAH_17750 panC pantoate--beta-alanine ligase 0.24 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.50 OHPLBJKB_03528 Pantothenate synthetase 0.24 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 73
Escherichia coli ECRC101 0.50 OKFHMN_10405 panC pantoate--beta-alanine ligase 0.24 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC102 0.50 NIAGMN_08255 panC pantoate--beta-alanine ligase 0.24 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC98 0.50 JDDGAC_14000 panC pantoate--beta-alanine ligase 0.24 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECOR38 0.50 HEPCGN_08380 panC pantoate--beta-alanine ligase 0.24 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 85
Escherichia coli ECOR27 0.50 NOLOHH_02750 panC pantoate--beta-alanine ligase 0.24 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 57
Serratia liquefaciens MT49 0.50 IAI46_21245 pantoate--beta-alanine ligase 0.23 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Escherichia coli ECRC62 0.50 BNILDI_08920 panC pantoate--beta-alanine ligase 0.24 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli BL21 0.50 ECD_00132 pantothenate synthetase 0.24 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase low > 60
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF92 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.23 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 78
Vibrio cholerae E7946 ATCC 55056 0.50 CSW01_03130 pantoate--beta-alanine ligase 0.23 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Acinetobacter radioresistens SK82 0.49 MPMX26_00546 Pantothenate synthetase 0.36 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Klebsiella michiganensis M5al 0.49 BWI76_RS04990 pantoate--beta-alanine ligase 0.23 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 92
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS00820 pantoate--beta-alanine ligase 0.22 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Pectobacterium carotovorum WPP14 0.49 HER17_RS05555 pantoate--beta-alanine ligase 0.25 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Erwinia tracheiphila SCR3 0.49 LU632_RS20105 panC pantoate--beta-alanine ligase 0.22 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Dickeya dadantii 3937 0.49 DDA3937_RS15960 pantoate--beta-alanine ligase 0.21 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.79 50
Rahnella sp. WP5 0.48 EX31_RS03285 pantoate--beta-alanine ligase 0.23 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 89
Dickeya dianthicola ME23 0.48 DZA65_RS17160 pantoate--beta-alanine ligase 0.20 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.76 41
Lysobacter sp. OAE881 0.48 ABIE51_RS08030 pantoate--beta-alanine ligase 0.20 ABIE51_RS07970 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Pantoea sp. MT58 0.48 IAI47_15660 pantoate--beta-alanine ligase 0.21 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_03890 panC pantoate--beta-alanine ligase 0.20 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 52
Dickeya dianthicola 67-19 0.47 HGI48_RS16075 pantoate--beta-alanine ligase 0.21 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.79 46
Magnetospirillum magneticum AMB-1 0.47 AMB_RS22115 pantoate--beta-alanine ligase 0.23 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Enterobacter asburiae PDN3 0.46 EX28DRAFT_3729 pantoate--beta-alanine ligase 0.23 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Rhodospirillum rubrum S1H 0.46 Rru_A3320 Cytidyltransferase-related (NCBI) 0.25 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) — —
Dechlorosoma suillum PS 0.46 Dsui_1470 pantoate--beta-alanine ligase 0.38 Dsui_0662 phosphomethylpyrimidine kinase — —
Enterobacter sp. TBS_079 0.46 MPMX20_00826 Pantothenate synthetase 0.23 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.21 55
Dinoroseobacter shibae DFL-12 0.44 Dshi_2952 pantoate--beta-alanine ligase (RefSeq) 0.17 Dshi_0915 phosphomethylpyrimidine kinase (RefSeq) — —
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS15520 pantoate--beta-alanine ligase 0.29 HSERO_RS02135 phosphomethylpyrimidine kinase — —
Ralstonia solanacearum GMI1000 0.44 RS_RS11985 pantoate--beta-alanine ligase 0.25 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Sinorhizobium meliloti 1021 0.44 SMc01880 pantoate--beta-alanine ligase 0.20 SM_b20962 phoshomethylpyrimidine kinase low > 103
Sphingomonas koreensis DSMZ 15582 0.44 Ga0059261_2453 pantoate--beta-alanine ligase 0.21 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Azospirillum brasilense Sp245 0.44 AZOBR_RS09715 pantoate--beta-alanine ligase 0.22 AZOBR_RS07045 phosphomethylpyrimidine kinase — —
Ralstonia solanacearum IBSBF1503 0.43 RALBFv3_RS04435 pantoate--beta-alanine ligase 0.25 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum UW163 0.43 UW163_RS09235 pantoate--beta-alanine ligase 0.25 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Agrobacterium fabrum C58 0.43 Atu3482 pantoate--beta-alanine ligase 0.23 Atu3290 phosphomethylpyrimidine kinase 0.80 43
Variovorax sp. SCN45 0.43 GFF2578 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.16 GFF2149 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 127
Caulobacter crescentus NA1000 0.43 CCNA_02247 pantoate-beta-alanine ligase 0.22 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Caulobacter crescentus NA1000 Δfur 0.43 CCNA_02247 pantoate-beta-alanine ligase 0.22 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase — —
Xanthomonas campestris pv. campestris strain 8004 0.43 Xcc-8004.3051.1 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.23 Xcc-8004.3091.1 hypothetical protein — —
Paraburkholderia sabiae LMG 24235 0.42 QEN71_RS25065 pantoate--beta-alanine ligase 0.20 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS00030 pantoate--beta-alanine ligase 0.24 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum PSI07 0.42 RPSI07_RS12935 pantoate--beta-alanine ligase 0.25 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS16055 pantothenate synthetase 0.19 RR42_RS01370 phosphomethylpyrimidine kinase — —
Paraburkholderia graminis OAS925 0.42 ABIE53_001260 pantoate--beta-alanine ligase 0.20 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Variovorax sp. OAS795 0.42 ABID97_RS07430 pantoate--beta-alanine ligase 0.19 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Paraburkholderia bryophila 376MFSha3.1 0.41 H281DRAFT_00150 pantothenate synthetase 0.22 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase — —
Rhizobium sp. OAE497 0.41 ABIE40_RS09460 pantoate--beta-alanine ligase 0.25 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 107
Bosea sp. OAE506 0.41 ABIE41_RS14875 pantoate--beta-alanine ligase 0.24 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.41 A4249_RS06825 pantoate--beta-alanine ligase 0.21 A4249_RS15985 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS04925 pantothenate synthetase 0.20 BPHYT_RS12250 phosphomethylpyrimidine kinase — —
Rhodopseudomonas palustris CGA009 0.41 TX73_016310 pantoate--beta-alanine ligase 0.21 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Azospirillum sp. SherDot2 0.41 MPMX19_04465 Pantothenate synthetase 0.20 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Castellaniella sp019104865 MT123 0.40 ABCV34_RS14585 pantoate--beta-alanine ligase 0.20 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Bacteroides stercoris CC31F 0.40 HMPREF1181_RS06090 pantoate--beta-alanine ligase 0.25 HMPREF1181_RS14705 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS18500 pantoate--beta-alanine ligase 0.24 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Bacteroides ovatus ATCC 8483 0.39 BACOVA_05108 pantoate--beta-alanine ligase 0.25 BACOVA_02530 phosphomethylpyrimidine kinase — —
Bacteroides thetaiotaomicron VPI-5482 0.39 BT4308 pantoate--beta-alanine ligase (NCBI ptt file) 0.26 BT0790 phosphomethylpyrimidine kinase (NCBI ptt file) — —
Desulfovibrio vulgaris Miyazaki F 0.38 DvMF_2942 panC pantoate--beta-alanine ligase (RefSeq) 0.20 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.37 PGA1_c32040 pantothenate synthetase PanC 0.14 PGA1_c09030 phosphomethylpyrimidine kinase ThiD — —
Phocaeicola vulgatus CL09T03C04 0.37 HMPREF1058_RS18260 pantoate--beta-alanine ligase 0.22 HMPREF1058_RS06820 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Parabacteroides merdae CL09T00C40 0.37 HMPREF1078_RS14680 pantoate--beta-alanine ligase 0.20 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 61
Phocaeicola dorei CL03T12C01 0.37 ABI39_RS14555 pantoate--beta-alanine ligase 0.23 ABI39_RS20615 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.36 CA264_17615 pantoate--beta-alanine ligase 0.20 CA264_20430 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Pedobacter sp. GW460-11-11-14-LB5 0.36 CA265_RS22700 pantoate--beta-alanine ligase 0.19 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Acidovorax sp. GW101-3H11 0.36 Ac3H11_3840 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.19 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Desulfovibrio vulgaris Hildenborough JW710 0.36 DVU2448 panC pantoate--beta-alanine ligase (TIGR) 0.18 DVU0931 thiD phosphomethylpyrimidine kinase (TIGR) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF1220 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.23 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.36 Echvi_1527 pantoate--beta-alanine ligase 0.23 Echvi_0215 phosphomethylpyrimidine kinase — —
Mycobacterium tuberculosis H37Rv 0.33 Rv3602c Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.17 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) — —

Not shown: 8 genomes with orthologs for PS417_23915 only; 4 genomes with orthologs for PS417_24600 only