Conservation of cofitness between GFF66 and GFF3534 in Sphingobium sp. HT1-2

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF66 Cobyric acid synthase (EC 6.3.5.10) 1.0 GFF3534 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.78 13
Sphingomonas koreensis DSMZ 15582 0.72 Ga0059261_0630 adenosylcobyric acid synthase (glutamine-hydrolysing) (EC 6.3.5.10) 0.86 Ga0059261_0926 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase low > 68
Azospirillum brasilense Sp245 0.62 AZOBR_RS09845 cobyric acid synthase 0.56 AZOBR_RS07460 anthranilate synthase
Azospirillum sp. SherDot2 0.59 MPMX19_01025 Cobyric acid synthase 0.57 MPMX19_01016 Anthranilate synthase component 2
Caulobacter crescentus NA1000 0.57 CCNA_02776 cobyric acid synthase CobQ 0.61 CCNA_01974 anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II low > 66
Caulobacter crescentus NA1000 Δfur 0.57 CCNA_02776 cobyric acid synthase CobQ 0.61 CCNA_01974 anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II low > 67
Bosea sp. OAE506 0.53 ABIE41_RS03845 cobyric acid synthase 0.55 ABIE41_RS17415 aminodeoxychorismate/anthranilate synthase component II
Rhodospirillum rubrum S1H 0.53 Rru_A3381 Cobyric acid synthase CobQ (NCBI) 0.53 Rru_A1895 Glutamine amidotransferase of anthranilate synthase (NCBI) low > 58
Xanthobacter sp. DMC5 0.52 GFF372 Cobyric acid synthase 0.55 GFF952 Anthranilate synthase component 2
Magnetospirillum magneticum AMB-1 0.51 AMB_RS01485 cobyric acid synthase 0.54 AMB_RS14405 type 1 glutamine amidotransferase
Phaeobacter inhibens DSM 17395 0.51 PGA1_c24000 cobyric acid synthase CobQ 0.58 PGA1_c16880 anthranilate synthase component II
Dinoroseobacter shibae DFL-12 0.50 Dshi_2096 cobyric acid synthase CobQ (RefSeq) 0.56 Dshi_1798 glutamine amidotransferase of anthranilate synthase (RefSeq)
Pseudomonas putida KT2440 0.45 PP_1677 Adenosyl-cobyric acid synthase 0.52 PP_0420 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex 0.33 69
Methylophilus sp. DMC18 0.45 GFF1471 Cobyric acid synthase 0.54 GFF2048 Anthranilate synthase component 2
Pseudomonas sp. BP01 0.45 JOY50_RS27965 cobyric acid synthase 0.52 JOY50_RS18230 aminodeoxychorismate/anthranilate synthase component II low > 84
Ralstonia sp. UNC404CL21Col 0.44 ABZR87_RS00040 cobyric acid synthase 0.49 ABZR87_RS02145 aminodeoxychorismate/anthranilate synthase component II low > 80
Ralstonia solanacearum GMI1000 0.44 RS_RS12000 cobyric acid synthase 0.51 RS_RS14435 type 1 glutamine amidotransferase
Paraburkholderia graminis OAS925 0.44 ABIE53_001255 adenosylcobyric acid synthase 0.49 ABIE53_003641 anthranilate synthase component 2
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_00146 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.49 H281DRAFT_05714 anthranilate synthase, component II low > 103
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS04900 cobyric acid synthase 0.49 BPHYT_RS17395 anthranilate synthase subunit II 0.36 55
Ralstonia solanacearum UW163 0.44 UW163_RS09225 cobyric acid synthase 0.50 UW163_RS07135 type 1 glutamine amidotransferase
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS04445 cobyric acid synthase 0.50 RALBFv3_RS06490 type 1 glutamine amidotransferase low > 76
Paraburkholderia sabiae LMG 24235 0.44 QEN71_RS25095 cobyric acid synthase 0.49 QEN71_RS27555 aminodeoxychorismate/anthranilate synthase component II low > 153
Ralstonia solanacearum PSI07 0.43 RPSI07_RS12925 cobyric acid synthase 0.51 RPSI07_RS10750 type 1 glutamine amidotransferase
Pseudomonas aeruginosa PA14 0.43 IKLFDK_06055 cobyric acid synthase 0.54 IKLFDK_22180 aminodeoxychorismate/anthranilate synthase component II low > 100
Pseudomonas stutzeri RCH2 0.43 Psest_3008 cobyric acid synthase CobQ 0.54 Psest_3649 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase low > 67
Pseudomonas segetis P6 0.43 MPMX49_01822 Cobyric acid synthase 0.53 MPMX49_00890 Anthranilate synthase component 2
Pseudomonas sp. SVBP6 0.43 COO64_RS07225 cobyric acid synthase 0.53 COO64_RS22420 aminodeoxychorismate/anthranilate synthase component II low > 93
Pseudomonas sp. DMC3 0.43 GFF2552 Cobyric acid synthase 0.53 GFF18 Anthranilate synthase component 2 low > 89
Pseudomonas fluorescens FW300-N2E2 0.42 Pf6N2E2_5742 Cobyric acid synthase (EC 6.3.5.10) 0.52 Pf6N2E2_4824 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) low > 103
Pseudomonas sp. S08-1 0.42 OH686_04965 cobyric acid synthase CobQ 0.53 OH686_15130 Anthranilate synthase, amidotransferase component or Para-aminobenzoate synthase, amidotransferase component
Shewanella sp. ANA-3 0.42 Shewana3_3275 cobyric acid synthase (RefSeq) 0.49 Shewana3_0606 aminodeoxychorismate synthase, glutamine amidotransferase subunit (RefSeq) low > 73
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4238 Cobyric acid synthase (EC 6.3.5.10) 0.52 PfGW456L13_1220 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) low > 87
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS16075 cobyric acid synthase 0.49 RR42_RS18300 anthranilate synthase subunit II low > 128
Pseudomonas fluorescens FW300-N2C3 0.42 AO356_19160 cobyric acid synthase 0.53 AO356_14430 anthranilate synthase 0.47 25
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_02615 cobyric acid synthase 0.53 AO353_07220 anthranilate synthase 0.40 34
Pseudomonas syringae pv. syringae B728a 0.42 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.53 Psyr_4581 anthranilate synthase, component II low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.42 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.53 Psyr_4581 anthranilate synthase, component II
Vibrio cholerae E7946 ATCC 55056 0.42 CSW01_17810 cobyric acid synthase CobQ 0.53 CSW01_13255 aminodeoxychorismate/anthranilate synthase component II low > 62
Dechlorosoma suillum PS 0.41 Dsui_0542 cobyric acid synthase CobQ 0.54 Dsui_0170 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase
Shewanella loihica PV-4 0.41 Shew_0717 cobyric acid synthase (RefSeq) 0.49 Shew_0575 glutamine amidotransferase of anthranilate synthase (RefSeq) low > 60
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3711 Cobyric acid synthase (EC 6.3.5.10) 0.52 Pf1N1B4_2547 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) low > 87
Pseudomonas simiae WCS417 0.41 PS417_20040 cobyric acid synthase 0.52 PS417_25720 anthranilate synthase component II low > 88
Pseudomonas fluorescens SBW25 0.41 PFLU_RS22005 cobyric acid synthase 0.52 PFLU_RS27375 aminodeoxychorismate/anthranilate synthase component II low > 109
Pseudomonas lactucae CFBP13502 0.41 GEMAOFIL_04205 Cobyric acid synthase 0.53 GEMAOFIL_05264 Anthranilate synthase component 2 low > 93
Lysobacter sp. OAE881 0.41 ABIE51_RS04965 cobyric acid synthase 0.52 ABIE51_RS04175 aminodeoxychorismate/anthranilate synthase component II low > 62
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS22005 cobyric acid synthase 0.52 PFLU_RS27375 aminodeoxychorismate/anthranilate synthase component II 0.39 57
Shewanella oneidensis MR-1 0.41 SO1038 cobQ cobyric acid synthase CobQ (NCBI ptt file) 0.48 SO0613 pabA para-aminobenzoate synthase glutamine amidotransferase, component II (NCBI ptt file) low > 76
Rhodanobacter sp. FW510-T8 0.41 OKGIIK_05500 cobyric acid synthase 0.54 OKGIIK_12290 pabA anthranilate/aminodeoxychorismate synthase component II low > 53
Pseudomonas sp. RS175 0.41 PFR28_03204 Cobyric acid synthase 0.53 PFR28_04045 Anthranilate synthase component 2
Herbaspirillum seropedicae SmR1 0.40 HSERO_RS13230 cobyric acid synthase 0.50 HSERO_RS19440 anthranilate synthase subunit II
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS10900 cobyric acid synthase 0.55 ABZR86_RS12075 aminodeoxychorismate/anthranilate synthase component II
Shewanella amazonensis SB2B 0.39 Sama_0765 cobyric acid synthase (RefSeq) 0.48 Sama_3015 para-aminobenzoate synthase glutamine amidotransferase, component II (RefSeq) low > 62
Mycobacterium tuberculosis H37Rv 0.38 Rv0255c Probable cobyric acid synthase CobQ1 0.49 Rv0013 Possible anthranilate synthase component II TrpG (glutamine amidotransferase)
Klebsiella michiganensis M5al 0.38 BWI76_RS23010 cobyric acid synthase CobQ 0.51 BWI76_RS26005 glutamine amidotransferase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.37 GFF3966 Cobyric acid synthase (EC 6.3.5.10) 0.52 GFF3709 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) low > 78
Klebsiella pneumoniae MKP103 0.37 KDGMDA_03575 cobyric acid synthase 0.52 KDGMDA_06835 aminodeoxychorismate synthase component 2 low > 95
Synechocystis sp000284455 PCC 6803 0.34 SGL_RS15620 cobyric acid synthase CobQ 0.50 SGL_RS13880 aminodeoxychorismate/anthranilate synthase component II
Synechococcus elongatus PCC 7942 0.34 Synpcc7942_0211 cobQ cobyric acid synthase 0.46 Synpcc7942_0400 trpG anthranilate synthase, component II
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS01395 cobyric acid synthase 0.37 HMPREF1058_RS07180 aminodeoxychorismate/anthranilate synthase component II low > 67
Desulfovibrio vulgaris Hildenborough JW710 0.33 DVU0816 cobQ cobyric acid synthase CobQ (TIGR) 0.38 DVU0466 trpG anthranilate synthase, glutamine amidotransferase component (TIGR) 0.57 52
Phocaeicola dorei CL03T12C01 0.33 ABI39_RS15660 cobyric acid synthase 0.37 ABI39_RS21055 aminodeoxychorismate/anthranilate synthase component II low > 72
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS00930 cobyric acid synthase 0.34 HMPREF1078_RS00140 aminodeoxychorismate/anthranilate synthase component II low > 61
Methanococcus maripaludis JJ 0.33 MMJJ_RS08095 cobyric acid synthase CobQ 0.40 MMJJ_RS09180 aminodeoxychorismate/anthranilate synthase component II
Methanococcus maripaludis S2 0.32 MMP_RS06255 cobyric acid synthase CobQ 0.41 MMP_RS05200 aminodeoxychorismate/anthranilate synthase component II
Fusobacterium nucleatum SB010 0.32 HUW76_05230 cobyric acid synthase 0.41 HUW76_10210 aminodeoxychorismate/anthranilate synthase component II low > 35
Hydrogenophaga sp. GW460-11-11-14-LB1 0.32 GFF3998 Cobyric acid synthase (EC 6.3.5.10) 0.47 GFF3107 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) low > 90
Variovorax sp. SCN45 0.31 GFF426 Cobyric acid synthase (EC 6.3.5.10) 0.49 GFF5894 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85)
Acidovorax sp. GW101-3H11 0.31 Ac3H11_999 Cobyric acid synthase (EC 6.3.5.10) 0.50 Ac3H11_769 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) low > 79
Desulfovibrio vulgaris Miyazaki F 0.31 DvMF_2864 cobyric acid synthase (RefSeq) 0.38 DvMF_1745 glutamine amidotransferase of anthranilate synthase (RefSeq)
Variovorax sp. OAS795 0.30 ABID97_RS17340 cobyric acid synthase 0.49 ABID97_RS05260 aminodeoxychorismate/anthranilate synthase component II low > 91

Not shown: 4 genomes with orthologs for GFF66 only; 45 genomes with orthologs for GFF3534 only