| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 1.0 | GFF4099 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 1.0 | GFF3363 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.63 | 12 |
| Acidovorax sp. GW101-3H11 | 0.92 | Ac3H11_941 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.90 | Ac3H11_1525 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Variovorax sp. OAS795 | 0.91 | ABID97_RS17550 | | fumarate hydratase | 0.88 | ABID97_RS08465 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Variovorax sp. SCN45 | 0.91 | GFF483 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.89 | GFF3890 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | low | > 127 |
| Herbaspirillum seropedicae SmR1 | 0.82 | HSERO_RS07760 | | fumarate hydratase | 0.71 | HSERO_RS16515 | | isopropylmalate isomerase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.78 | RR42_RS13905 | | fumarate hydratase | 0.75 | RR42_RS14400 | | isopropylmalate isomerase | low | > 128 |
| Ralstonia solanacearum PSI07 | 0.78 | RPSI07_RS14865 | | fumarate hydratase | 0.75 | RPSI07_RS14695 | | 3-isopropylmalate dehydratase large subunit | low | > 81 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.77 | H281DRAFT_04956 | | fumarase, class I, homodimeric | 0.74 | H281DRAFT_06075 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Burkholderia phytofirmans PsJN | 0.77 | BPHYT_RS06985 | | fumarate hydratase | 0.74 | BPHYT_RS33915 | | isopropylmalate isomerase | low | > 109 |
| Paraburkholderia graminis OAS925 | 0.77 | ABIE53_001662 | | fumarate hydratase class I | 0.74 | ABIE53_004801 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | low | > 113 |
| Ralstonia solanacearum GMI1000 | 0.77 | RS_RS09830 | | fumarate hydratase | 0.75 | RS_RS10000 | | 3-isopropylmalate dehydratase large subunit | low | > 80 |
| Ralstonia sp. UNC404CL21Col | 0.77 | ABZR87_RS14375 | | fumarate hydratase | 0.76 | ABZR87_RS14540 | | 3-isopropylmalate dehydratase large subunit | low | > 80 |
| Ralstonia solanacearum UW163 | 0.76 | UW163_RS11265 | | fumarate hydratase | 0.75 | UW163_RS11105 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.76 | RALBFv3_RS02460 | | fumarate hydratase | 0.75 | RALBFv3_RS02620 | | 3-isopropylmalate dehydratase large subunit | low | > 76 |
| Paraburkholderia sabiae LMG 24235 | 0.76 | QEN71_RS23780 | | fumarate hydratase | 0.74 | QEN71_RS17605 | | 3-isopropylmalate dehydratase large subunit | low | > 153 |
| Dyella japonica UNC79MFTsu3.2 | 0.75 | ABZR86_RS19555 | | fumarate hydratase | 0.50 | ABZR86_RS15960 | | 3-isopropylmalate dehydratase large subunit | low | > 74 |
| Lysobacter sp. OAE881 | 0.73 | ABIE51_RS12620 | | fumarate hydratase | 0.46 | ABIE51_RS17575 | | 3-isopropylmalate dehydratase large subunit | low | > 62 |
| Rhodanobacter sp. FW510-T8 | 0.73 | OKGIIK_02115 | ttdA | fumarate hydratase | 0.47 | OKGIIK_13585 | leuC | 3-isopropylmalate dehydratase large subunit | low | > 52 |
| Rhodanobacter denitrificans MT42 | 0.73 | LRK55_RS12360 | | fumarate hydratase | 0.56 | LRK55_RS07105 | | 3-isopropylmalate dehydratase large subunit | low | > 63 |
| Castellaniella sp019104865 MT123 | 0.73 | ABCV34_RS09450 | | fumarate hydratase | 0.70 | ABCV34_RS04290 | | 3-isopropylmalate dehydratase large subunit | low | > 48 |
| Rhodanobacter denitrificans FW104-10B01 | 0.73 | LRK54_RS12620 | | fumarate hydratase | 0.56 | LRK54_RS07375 | | 3-isopropylmalate dehydratase large subunit | low | > 59 |
| Dechlorosoma suillum PS | 0.72 | Dsui_2001 | | hydro-lyase, Fe-S type, tartrate/fumarate subfamily,hydro-lyase family enzyme, Fe-S type, tartrate/fumarate subfamily | 0.72 | Dsui_3201 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.72 | Xcc-8004.3506.1 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.68 | Xcc-8004.1049.1 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Pseudomonas simiae WCS417 | 0.72 | PS417_22635 | | fumarate hydratase | 0.69 | PS417_18600 | | isopropylmalate isomerase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.71 | Psyr_4031 | | fumarase | 0.69 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Pseudomonas fluorescens SBW25 | 0.71 | PFLU_RS24270 | | fumarate hydratase | 0.68 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.71 | PFLU_RS24270 | | fumarate hydratase | 0.68 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.71 | Psyr_4031 | | fumarase | 0.69 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.71 | Pf1N1B4_683 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.69 | Pf1N1B4_15 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | low | > 87 |
| Pseudomonas fluorescens GW456-L13 | 0.71 | PfGW456L13_1808 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.69 | PfGW456L13_3948 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.71 | AO353_03795 | | fumarate hydratase | 0.68 | AO353_20620 | | isopropylmalate isomerase | low | > 101 |
| Pseudomonas fluorescens FW300-N2E2 | 0.71 | Pf6N2E2_5489 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.68 | Pf6N2E2_63 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Pseudomonas sp. RS175 | 0.71 | PFR28_03458 | | Fumarate hydratase class I, aerobic | 0.69 | PFR28_02824 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas stutzeri RCH2 | 0.71 | Psest_3193 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | 0.66 | Psest_2591 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.71 | AO356_17810 | | fumarate hydratase | 0.69 | AO356_21400 | | isopropylmalate isomerase | — | — |
| Pseudomonas putida KT2440 | 0.71 | PP_0897 | | Fumarate hydratase, class I | 0.68 | PP_1985 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas sp. S08-1 | 0.70 | OH686_18780 | | Fumarate hydratase class I, aerobic | 0.66 | OH686_04480 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Acinetobacter radioresistens SK82 | 0.68 | MPMX26_00411 | | Fumarate hydratase class I, aerobic | 0.66 | MPMX26_00345 | | 3-isopropylmalate dehydratase large subunit | low | > 36 |
| Shewanella loihica PV-4 | 0.67 | Shew_1904 | | tartrate/fumarate subfamily Fe-S type hydro-lyase alpha subunit (RefSeq) | 0.58 | Shew_3470 | | isopropylmalate isomerase large subunit (RefSeq) | — | — |
| Kangiella aquimarina DSM 16071 | 0.67 | B158DRAFT_1342 | | fumarase, class I, homodimeric (EC 4.2.1.2) | 0.67 | B158DRAFT_1319 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Marinobacter adhaerens HP15 | 0.67 | HP15_1143 | | hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit | 0.68 | HP15_1834 | | protein containing 3-isopropylmalate dehydratase, large subunit region domain | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.67 | Ga0059261_3334 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | 0.57 | Ga0059261_4223 | | 3-isopropylmalate dehydratase, large subunit | low | > 68 |
| Shewanella amazonensis SB2B | 0.66 | Sama_1688 | | fumarate hydratase, class I, anaerobic, putative (RefSeq) | 0.58 | Sama_0337 | | isopropylmalate isomerase large subunit (RefSeq) | — | — |
| Shewanella oneidensis MR-1 | 0.66 | SO2222 | | fumarate hydratase, class I, anaerobic, putative (NCBI ptt file) | 0.58 | SO4234 | leuC | 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) | — | — |
| Alteromonas macleodii MIT1002 | 0.65 | MIT1002_02009 | | Fumarate hydratase class I, anaerobic | 0.56 | MIT1002_00947 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Shewanella sp. ANA-3 | 0.65 | Shewana3_2302 | | fumarase (RefSeq) | 0.58 | Shewana3_3759 | | isopropylmalate isomerase large subunit (RefSeq) | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.64 | CSW01_06585 | | fumarate hydratase | 0.58 | CSW01_12605 | | 3-isopropylmalate dehydratase large subunit | low | > 62 |
| Dinoroseobacter shibae DFL-12 | 0.55 | Dshi_1426 | | hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit (RefSeq) | 0.59 | Dshi_0085 | | 3-isopropylmalate dehydratase, large subunit (RefSeq) | low | > 64 |
| Rhodopseudomonas palustris CGA009 | 0.21 | TX73_020085 | | fumarate hydratase | 0.63 | TX73_001245 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Enterobacter asburiae PDN3 | 0.20 | EX28DRAFT_1609 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | 0.59 | EX28DRAFT_3668 | | 3-isopropylmalate dehydratase, large subunit | low | > 76 |
| Escherichia coli ECOR38 | 0.20 | HEPCGN_06020 | fumB | class I fumarate hydratase | 0.60 | HEPCGN_08705 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | low | > 85 |
| Escherichia coli ECOR27 | 0.20 | NOLOHH_18150 | fumB | class I fumarate hydratase | 0.60 | NOLOHH_03070 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | low | > 57 |
| Escherichia coli ECRC62 | 0.20 | BNILDI_16940 | fumB | class I fumarate hydratase | 0.60 | BNILDI_08540 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC101 | 0.20 | OKFHMN_12525 | fumB | class I fumarate hydratase | 0.59 | OKFHMN_10725 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli BW25113 | 0.20 | b1612 | fumA | fumarate hydratase (fumarase A), aerobic Class I (NCBI) | 0.60 | b0072 | leuC | isopropylmalate isomerase large subunit (NCBI) | low | > 76 |
| Escherichia coli Nissle 1917 | 0.20 | ECOLIN_RS09000 | | class I fumarate hydratase | 0.60 | ECOLIN_RS00390 | | 3-isopropylmalate dehydratase large subunit | low | > 52 |
| Enterobacter sp. TBS_079 | 0.20 | MPMX20_02021 | | Fumarate hydratase class I, aerobic | 0.59 | MPMX20_00767 | | 3-isopropylmalate dehydratase large subunit 1 | low | > 85 |
| Escherichia fergusonii Becca | 0.20 | EFB2_02380 | | Fumarate hydratase class I, aerobic | 0.60 | EFB2_03973 | | 3-isopropylmalate dehydratase large subunit | low | > 86 |
| Escherichia coli ECRC102 | 0.20 | NIAGMN_10370 | fumB | class I fumarate hydratase | 0.59 | NIAGMN_08575 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli BL21 | 0.20 | ECD_01581 | | fumarate hydratase (fumarase A), aerobic Class I | 0.60 | ECD_00074 | | 3-isopropylmalate dehydratase large subunit | low | > 60 |
| Magnetospirillum magneticum AMB-1 | 0.20 | AMB_RS06760 | | fumarate hydratase | 0.61 | AMB_RS20560 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Rhizobium sp. OAE497 | 0.20 | ABIE40_RS10550 | | fumarate hydratase | 0.65 | ABIE40_RS18380 | | 3-isopropylmalate dehydratase large subunit | low | > 107 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.20 | OHPLBJKB_03922 | | Fumarate hydratase class I, anaerobic | 0.59 | OHPLBJKB_03585 | | 3-isopropylmalate dehydratase large subunit | low | > 73 |
| Escherichia coli ECRC98 | 0.20 | JDDGAC_16160 | fumB | class I fumarate hydratase | 0.59 | JDDGAC_14320 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC101 | 0.20 | MCAODC_03035 | fumB | class I fumarate hydratase | 0.59 | MCAODC_01240 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC99 | 0.20 | KEDOAH_15640 | fumB | class I fumarate hydratase | 0.59 | KEDOAH_17430 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.19 | GFF1477 | | Fumarate hydratase class I, anaerobic (EC 4.2.1.2) | 0.59 | GFF166 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | low | > 78 |
| Rhodospirillum rubrum S1H | 0.19 | Rru_A2206 | | tartrate dehydrogenase (NCBI) | 0.66 | Rru_A1189 | | 3-isopropylmalate dehydratase large subunit region (NCBI) | — | — |
| Bacteroides thetaiotaomicron VPI-5482 | 0.19 | BT2256 | | fumarate hydratase class I, anaerobic (NCBI ptt file) | 0.50 | BT1860 | | 3-isopropylmalate dehydratase large subunit (NCBI ptt file) | — | — |
| Klebsiella michiganensis M5al | 0.19 | BWI76_RS08450 | | fumarate hydratase | 0.59 | BWI76_RS04670 | | 3-isopropylmalate dehydratase large subunit | low | > 92 |
| Serratia liquefaciens MT49 | 0.19 | IAI46_21370 | | fumarate hydratase | 0.59 | IAI46_03345 | | 3-isopropylmalate dehydratase large subunit | low | > 86 |
| Parabacteroides merdae CL09T00C40 | 0.19 | HMPREF1078_RS17710 | | fumarate hydratase | 0.50 | HMPREF1078_RS16660 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Rahnella sp. WP5 | 0.19 | EX31_RS01160 | | fumarate hydratase | 0.60 | EX31_RS03690 | | 3-isopropylmalate dehydratase large subunit | low | > 89 |
| Azospirillum brasilense Sp245 | 0.19 | AZOBR_RS10315 | | fumarate hydratase | 0.66 | AZOBR_RS03545 | | isopropylmalate isomerase | low | > 97 |
| Bacteroides stercoris CC31F | 0.19 | HMPREF1181_RS09470 | | fumarate hydratase | 0.50 | HMPREF1181_RS14145 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Bacteroides ovatus ATCC 8483 | 0.19 | BACOVA_03087 | | hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type | 0.50 | BACOVA_04603 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Erwinia tracheiphila SCR3 | 0.19 | LU632_RS01205 | | class I fumarate hydratase FumA | 0.56 | LU632_RS02870 | leuC | 3-isopropylmalate dehydratase large subunit | 0.70 | 32 |
| Phocaeicola vulgatus CL09T03C04 | 0.19 | HMPREF1058_RS13805 | | fumarate hydratase | 0.50 | HMPREF1058_RS14550 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Azospirillum sp. SherDot2 | 0.19 | MPMX19_03166 | | Fumarate hydratase class I, aerobic | 0.68 | MPMX19_01998 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Dickeya dadantii 3937 | 0.19 | DDA3937_RS04540 | | fumarate hydratase | 0.60 | DDA3937_RS18125 | | 3-isopropylmalate dehydratase large subunit | low | > 74 |
| Dickeya dianthicola ME23 | 0.19 | DZA65_RS04420 | | fumarate hydratase | 0.60 | DZA65_RS19210 | | 3-isopropylmalate dehydratase large subunit | low | > 75 |
| Pectobacterium carotovorum WPP14 | 0.18 | HER17_RS17120 | | fumarate hydratase | 0.59 | HER17_RS03075 | | 3-isopropylmalate dehydratase large subunit | low | > 75 |
| Dickeya dianthicola 67-19 | 0.18 | HGI48_RS04500 | | fumarate hydratase | 0.60 | HGI48_RS18065 | | 3-isopropylmalate dehydratase large subunit | low | > 71 |
| Pantoea sp. MT58 | 0.18 | IAI47_20435 | | fumarate hydratase | 0.60 | IAI47_16010 | | 3-isopropylmalate dehydratase large subunit | low | > 76 |
| Bosea sp. OAE506 | 0.18 | ABIE41_RS00110 | | fumarate hydratase | 0.63 | ABIE41_RS11660 | | 3-isopropylmalate dehydratase large subunit | — | — |
Not shown: 0 genomes with orthologs for GFF4099 only; 18 genomes with orthologs for GFF3363 only