| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 1.0 | GFF4099 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 1.0 | GFF3361 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.68 | 5 |
| Acidovorax sp. GW101-3H11 | 0.92 | Ac3H11_941 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.86 | Ac3H11_1527 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | — | — |
| Variovorax sp. OAS795 | 0.91 | ABID97_RS17550 | | fumarate hydratase | 0.91 | ABID97_RS08460 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Variovorax sp. SCN45 | 0.91 | GFF483 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.90 | GFF3889 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | low | > 127 |
| Herbaspirillum seropedicae SmR1 | 0.82 | HSERO_RS07760 | | fumarate hydratase | 0.73 | HSERO_RS16505 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.78 | RR42_RS13905 | | fumarate hydratase | 0.75 | RR42_RS14390 | | 3-isopropylmalate dehydratase | low | > 128 |
| Ralstonia solanacearum PSI07 | 0.78 | RPSI07_RS14865 | | fumarate hydratase | 0.80 | RPSI07_RS14700 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.77 | H281DRAFT_04956 | | fumarase, class I, homodimeric | 0.77 | H281DRAFT_06073 | | 3-isopropylmalate dehydratase, small subunit | — | — |
| Burkholderia phytofirmans PsJN | 0.77 | BPHYT_RS06985 | | fumarate hydratase | 0.76 | BPHYT_RS33905 | | 3-isopropylmalate dehydratase small subunit | low | > 109 |
| Paraburkholderia graminis OAS925 | 0.77 | ABIE53_001662 | | fumarate hydratase class I | 0.76 | ABIE53_004803 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit | low | > 113 |
| Ralstonia sp. UNC404CL21Col | 0.77 | ABZR87_RS14375 | | fumarate hydratase | 0.80 | ABZR87_RS14535 | | 3-isopropylmalate dehydratase small subunit | low | > 80 |
| Ralstonia solanacearum GMI1000 | 0.77 | RS_RS09830 | | fumarate hydratase | 0.80 | RS_RS09995 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.76 | RALBFv3_RS02460 | | fumarate hydratase | 0.80 | RALBFv3_RS02615 | | 3-isopropylmalate dehydratase small subunit | low | > 76 |
| Ralstonia solanacearum UW163 | 0.76 | UW163_RS11265 | | fumarate hydratase | 0.80 | UW163_RS11110 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.76 | QEN71_RS23780 | | fumarate hydratase | 0.76 | QEN71_RS17615 | | 3-isopropylmalate dehydratase small subunit | low | > 153 |
| Dyella japonica UNC79MFTsu3.2 | 0.75 | ABZR86_RS19555 | | fumarate hydratase | 0.40 | ABZR86_RS15955 | | 3-isopropylmalate dehydratase small subunit | low | > 74 |
| Rhodanobacter sp. FW510-T8 | 0.73 | OKGIIK_02115 | ttdA | fumarate hydratase | 0.38 | OKGIIK_13590 | leuD | 3-isopropylmalate dehydratase small subunit | low | > 52 |
| Rhodanobacter denitrificans MT42 | 0.73 | LRK55_RS12360 | | fumarate hydratase | 0.46 | LRK55_RS07100 | | 3-isopropylmalate dehydratase small subunit | low | > 63 |
| Lysobacter sp. OAE881 | 0.73 | ABIE51_RS12620 | | fumarate hydratase | 0.37 | ABIE51_RS17580 | | 3-isopropylmalate dehydratase small subunit | low | > 62 |
| Castellaniella sp019104865 MT123 | 0.73 | ABCV34_RS09450 | | fumarate hydratase | 0.68 | ABCV34_RS04285 | | 3-isopropylmalate dehydratase small subunit | low | > 48 |
| Rhodanobacter denitrificans FW104-10B01 | 0.73 | LRK54_RS12620 | | fumarate hydratase | 0.46 | LRK54_RS07370 | | 3-isopropylmalate dehydratase small subunit | low | > 59 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.72 | Xcc-8004.3506.1 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.67 | Xcc-8004.1050.1 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | — | — |
| Dechlorosoma suillum PS | 0.72 | Dsui_2001 | | hydro-lyase, Fe-S type, tartrate/fumarate subfamily,hydro-lyase family enzyme, Fe-S type, tartrate/fumarate subfamily | 0.67 | Dsui_3199 | | 3-isopropylmalate dehydratase, small subunit | — | — |
| Pseudomonas simiae WCS417 | 0.72 | PS417_22635 | | fumarate hydratase | 0.67 | PS417_18595 | | 3-isopropylmalate dehydratase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.71 | Psyr_4031 | | fumarase | 0.69 | Psyr_1984 | | 3-isopropylmalate dehydratase, small subunit | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.71 | PFLU_RS24270 | | fumarate hydratase | 0.68 | PFLU_RS20575 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.71 | Psyr_4031 | | fumarase | 0.69 | Psyr_1984 | | 3-isopropylmalate dehydratase, small subunit | — | — |
| Pseudomonas fluorescens SBW25 | 0.71 | PFLU_RS24270 | | fumarate hydratase | 0.68 | PFLU_RS20575 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.71 | PfGW456L13_1808 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.70 | PfGW456L13_3947 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.71 | Pf1N1B4_683 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.69 | Pf1N1B4_14 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.71 | AO353_03795 | | fumarate hydratase | 0.70 | AO353_20625 | | 3-isopropylmalate dehydratase | low | > 101 |
| Pseudomonas fluorescens FW300-N2E2 | 0.71 | Pf6N2E2_5489 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.69 | Pf6N2E2_64 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | — | — |
| Pseudomonas sp. RS175 | 0.71 | PFR28_03458 | | Fumarate hydratase class I, aerobic | 0.70 | PFR28_02823 | | 3-isopropylmalate dehydratase small subunit 1 | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.71 | AO356_17810 | | fumarate hydratase | 0.69 | AO356_21405 | | 3-isopropylmalate dehydratase | — | — |
| Pseudomonas stutzeri RCH2 | 0.71 | Psest_3193 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | 0.67 | Psest_2590 | | 3-isopropylmalate dehydratase, small subunit | — | — |
| Pseudomonas putida KT2440 | 0.71 | PP_0897 | | Fumarate hydratase, class I | 0.69 | PP_1986 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Pseudomonas sp. S08-1 | 0.70 | OH686_18780 | | Fumarate hydratase class I, aerobic | 0.68 | OH686_04475 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Acinetobacter radioresistens SK82 | 0.68 | MPMX26_00411 | | Fumarate hydratase class I, aerobic | 0.65 | MPMX26_00346 | | 3-isopropylmalate dehydratase small subunit 1 | low | > 36 |
| Shewanella loihica PV-4 | 0.67 | Shew_1904 | | tartrate/fumarate subfamily Fe-S type hydro-lyase alpha subunit (RefSeq) | 0.52 | Shew_3469 | | isopropylmalate isomerase small subunit (RefSeq) | — | — |
| Kangiella aquimarina DSM 16071 | 0.67 | B158DRAFT_1342 | | fumarase, class I, homodimeric (EC 4.2.1.2) | 0.66 | B158DRAFT_1320 | | 3-isopropylmalate dehydratase, small subunit | — | — |
| Marinobacter adhaerens HP15 | 0.67 | HP15_1143 | | hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit | 0.64 | HP15_1833 | | isopropylmalate isomerase small subunit | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.67 | Ga0059261_3334 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | 0.36 | Ga0059261_4225 | | 3-isopropylmalate dehydratase, small subunit | low | > 68 |
| Shewanella amazonensis SB2B | 0.66 | Sama_1688 | | fumarate hydratase, class I, anaerobic, putative (RefSeq) | 0.50 | Sama_0338 | leuD | isopropylmalate isomerase small subunit (RefSeq) | — | — |
| Shewanella oneidensis MR-1 | 0.66 | SO2222 | | fumarate hydratase, class I, anaerobic, putative (NCBI ptt file) | 0.51 | SO4233 | leuD | 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) | — | — |
| Alteromonas macleodii MIT1002 | 0.65 | MIT1002_02009 | | Fumarate hydratase class I, anaerobic | 0.46 | MIT1002_00946 | | 3-isopropylmalate dehydratase small subunit 1 | — | — |
| Shewanella sp. ANA-3 | 0.65 | Shewana3_2302 | | fumarase (RefSeq) | 0.51 | Shewana3_3758 | leuD | isopropylmalate isomerase small subunit (RefSeq) | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.64 | CSW01_06585 | | fumarate hydratase | 0.52 | CSW01_12610 | | 3-isopropylmalate dehydratase small subunit | low | > 62 |
| Dinoroseobacter shibae DFL-12 | 0.55 | Dshi_1426 | | hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit (RefSeq) | 0.54 | Dshi_0083 | | 3-isopropylmalate dehydratase, small subunit (RefSeq) | low | > 64 |
| Rhodopseudomonas palustris CGA009 | 0.21 | TX73_020085 | | fumarate hydratase | 0.51 | TX73_001215 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Enterobacter asburiae PDN3 | 0.20 | EX28DRAFT_1609 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | 0.53 | EX28DRAFT_3667 | | 3-isopropylmalate dehydratase, small subunit | low | > 76 |
| Escherichia coli BW25113 | 0.20 | b1612 | fumA | fumarate hydratase (fumarase A), aerobic Class I (NCBI) | 0.54 | b0071 | leuD | isopropylmalate isomerase small subunit (NCBI) | low | > 76 |
| Escherichia coli ECOR27 | 0.20 | NOLOHH_18150 | fumB | class I fumarate hydratase | 0.54 | NOLOHH_03075 | leuD | 3-isopropylmalate dehydratase small subunit | low | > 57 |
| Escherichia coli ECOR38 | 0.20 | HEPCGN_06020 | fumB | class I fumarate hydratase | 0.54 | HEPCGN_08710 | leuD | 3-isopropylmalate dehydratase small subunit | low | > 85 |
| Escherichia coli ECRC62 | 0.20 | BNILDI_16940 | fumB | class I fumarate hydratase | 0.54 | BNILDI_08535 | leuD | 3-isopropylmalate dehydratase small subunit | — | — |
| Escherichia coli ECRC101 | 0.20 | OKFHMN_12525 | fumB | class I fumarate hydratase | 0.54 | OKFHMN_10730 | leuD | 3-isopropylmalate dehydratase small subunit | — | — |
| Escherichia coli ECRC102 | 0.20 | NIAGMN_10370 | fumB | class I fumarate hydratase | 0.54 | NIAGMN_08580 | leuD | 3-isopropylmalate dehydratase small subunit | — | — |
| Enterobacter sp. TBS_079 | 0.20 | MPMX20_02021 | | Fumarate hydratase class I, aerobic | 0.54 | MPMX20_00766 | | 3-isopropylmalate dehydratase small subunit 1 | low | > 85 |
| Magnetospirillum magneticum AMB-1 | 0.20 | AMB_RS06760 | | fumarate hydratase | 0.57 | AMB_RS20565 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Escherichia coli BL21 | 0.20 | ECD_01581 | | fumarate hydratase (fumarase A), aerobic Class I | 0.54 | ECD_00073 | | 3-isopropylmalate dehydratase small subunit | low | > 60 |
| Escherichia coli Nissle 1917 | 0.20 | ECOLIN_RS09000 | | class I fumarate hydratase | 0.54 | ECOLIN_RS00385 | | 3-isopropylmalate dehydratase small subunit | low | > 52 |
| Escherichia fergusonii Becca | 0.20 | EFB2_02380 | | Fumarate hydratase class I, aerobic | 0.54 | EFB2_03974 | | 3-isopropylmalate dehydratase small subunit | low | > 86 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.20 | OHPLBJKB_03922 | | Fumarate hydratase class I, anaerobic | 0.54 | OHPLBJKB_03586 | | 3-isopropylmalate dehydratase small subunit | low | > 73 |
| Escherichia coli ECRC99 | 0.20 | KEDOAH_15640 | fumB | class I fumarate hydratase | 0.54 | KEDOAH_17425 | leuD | 3-isopropylmalate dehydratase small subunit | — | — |
| Escherichia coli ECRC101 | 0.20 | MCAODC_03035 | fumB | class I fumarate hydratase | 0.54 | MCAODC_01245 | leuD | 3-isopropylmalate dehydratase small subunit | — | — |
| Escherichia coli ECRC98 | 0.20 | JDDGAC_16160 | fumB | class I fumarate hydratase | 0.54 | JDDGAC_14325 | leuD | 3-isopropylmalate dehydratase small subunit | — | — |
| Rhizobium sp. OAE497 | 0.20 | ABIE40_RS10550 | | fumarate hydratase | 0.49 | ABIE40_RS19040 | | 3-isopropylmalate dehydratase small subunit | low | > 107 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.19 | GFF1477 | | Fumarate hydratase class I, anaerobic (EC 4.2.1.2) | 0.55 | GFF167 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | low | > 78 |
| Rhodospirillum rubrum S1H | 0.19 | Rru_A2206 | | tartrate dehydrogenase (NCBI) | 0.55 | Rru_A1190 | | 3-isopropylmalate dehydratase small subunit region (NCBI) | — | — |
| Serratia liquefaciens MT49 | 0.19 | IAI46_21370 | | fumarate hydratase | 0.56 | IAI46_03340 | | 3-isopropylmalate dehydratase small subunit | low | > 86 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.19 | BT2256 | | fumarate hydratase class I, anaerobic (NCBI ptt file) | 0.36 | BT1859 | | 3-isopropylmalate dehydratase small subunit (NCBI ptt file) | — | — |
| Klebsiella michiganensis M5al | 0.19 | BWI76_RS08450 | | fumarate hydratase | 0.54 | BWI76_RS04665 | | 3-isopropylmalate dehydratase small subunit | low | > 92 |
| Rahnella sp. WP5 | 0.19 | EX31_RS01160 | | fumarate hydratase | 0.56 | EX31_RS03695 | | 3-isopropylmalate dehydratase small subunit | low | > 89 |
| Azospirillum brasilense Sp245 | 0.19 | AZOBR_RS10315 | | fumarate hydratase | 0.50 | AZOBR_RS14135 | | isopropylmalate isomerase | low | > 97 |
| Parabacteroides merdae CL09T00C40 | 0.19 | HMPREF1078_RS17710 | | fumarate hydratase | 0.40 | HMPREF1078_RS16655 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Bacteroides stercoris CC31F | 0.19 | HMPREF1181_RS09470 | | fumarate hydratase | 0.39 | HMPREF1181_RS14140 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Bacteroides ovatus ATCC 8483 | 0.19 | BACOVA_03087 | | hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type | 0.36 | BACOVA_04602 | | 3-isopropylmalate dehydratase, small subunit | — | — |
| Erwinia tracheiphila SCR3 | 0.19 | LU632_RS01205 | | class I fumarate hydratase FumA | 0.52 | LU632_RS02865 | leuD | 3-isopropylmalate dehydratase small subunit | 0.73 | 20 |
| Phocaeicola vulgatus CL09T03C04 | 0.19 | HMPREF1058_RS13805 | | fumarate hydratase | 0.38 | HMPREF1058_RS14555 | | 3-isopropylmalate dehydratase small subunit | — | — |
| Azospirillum sp. SherDot2 | 0.19 | MPMX19_03166 | | Fumarate hydratase class I, aerobic | 0.53 | MPMX19_00606 | | 3-isopropylmalate dehydratase small subunit 1 | — | — |
| Dickeya dianthicola ME23 | 0.19 | DZA65_RS04420 | | fumarate hydratase | 0.55 | DZA65_RS19215 | | 3-isopropylmalate dehydratase small subunit | low | > 75 |
| Dickeya dadantii 3937 | 0.19 | DDA3937_RS04540 | | fumarate hydratase | 0.55 | DDA3937_RS18130 | | 3-isopropylmalate dehydratase small subunit | low | > 74 |
| Pectobacterium carotovorum WPP14 | 0.18 | HER17_RS17120 | | fumarate hydratase | 0.55 | HER17_RS03070 | | 3-isopropylmalate dehydratase small subunit | low | > 75 |
| Dickeya dianthicola 67-19 | 0.18 | HGI48_RS04500 | | fumarate hydratase | 0.55 | HGI48_RS18070 | | 3-isopropylmalate dehydratase small subunit | low | > 71 |
| Pantoea sp. MT58 | 0.18 | IAI47_20435 | | fumarate hydratase | 0.53 | IAI47_16015 | | 3-isopropylmalate dehydratase small subunit | low | > 76 |
| Bosea sp. OAE506 | 0.18 | ABIE41_RS00110 | | fumarate hydratase | 0.50 | ABIE41_RS11640 | | 3-isopropylmalate dehydratase small subunit | — | — |
Not shown: 0 genomes with orthologs for GFF4099 only; 13 genomes with orthologs for GFF3361 only