| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Sphingobium sp. HT1-2 | 1.0 | GFF1279 | | Uncharacterized protein YhiN | 1.0 | GFF3351 | | MFS family multidrug efflux protein, similarity to bicyclomycin resistance protein Bcr | 0.80 | 1 |
| Sphingomonas koreensis DSMZ 15582 | 0.71 | Ga0059261_3388 | | flavoprotein, HI0933 family | 0.38 | Ga0059261_2714 | | drug resistance transporter, Bcr/CflA subfamily | low | > 68 |
| Phaeobacter inhibens DSM 17395 | 0.53 | PGA1_c09590 | | uncharacterized protein YhiN | 0.23 | PGA1_c14930 | | putative MFS transporter | low | > 62 |
| Rhizobium sp. OAE497 | 0.52 | ABIE40_RS03215 | | NAD(P)/FAD-dependent oxidoreductase | 0.34 | ABIE40_RS10210 | | multidrug effflux MFS transporter | low | > 107 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.52 | GFF523 | | NAD(FAD)-utilizing dehydrogenases | 0.15 | GFF3754 | | MFS family multidrug transport protein, bicyclomycin resistance protein | low | > 78 |
| Sinorhizobium meliloti 1021 | 0.52 | SMc00763 | | hypothetical protein | 0.33 | SMc00536 | | transporter | low | > 103 |
| Caulobacter crescentus NA1000 Δfur | 0.52 | CCNA_01545 | | NAD(FAD)-utilizing dehydrogenase | 0.15 | CCNA_01288 | | multidrug resistance transporter, Bcr family | low | > 67 |
| Caulobacter crescentus NA1000 | 0.52 | CCNA_01545 | | NAD(FAD)-utilizing dehydrogenase | 0.15 | CCNA_01288 | | multidrug resistance transporter, Bcr family | low | > 66 |
| Rahnella sp. WP5 | 0.52 | EX31_RS05140 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | EX31_RS23035 | | multidrug effflux MFS transporter | low | > 89 |
| Magnetospirillum magneticum AMB-1 | 0.52 | AMB_RS17480 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | AMB_RS01475 | | MFS transporter | low | > 64 |
| Agrobacterium fabrum C58 | 0.51 | Atu0603 | | hypothetical protein | 0.33 | Atu1855 | | MFS permease | low | > 89 |
| Pectobacterium carotovorum WPP14 | 0.51 | HER17_RS21340 | | NAD(P)/FAD-dependent oxidoreductase | 0.15 | HER17_RS12945 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 75 |
| Dickeya dianthicola 67-19 | 0.51 | HGI48_RS21025 | | NAD(P)/FAD-dependent oxidoreductase | 0.18 | HGI48_RS09205 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 71 |
| Dickeya dianthicola ME23 | 0.51 | DZA65_RS22010 | | NAD(P)/FAD-dependent oxidoreductase | 0.18 | DZA65_RS09505 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 75 |
| Pseudomonas fluorescens FW300-N2E2 | 0.50 | Pf6N2E2_4672 | | FIG00953568: hypothetical protein | 0.13 | Pf6N2E2_3484 | | Multidrug resistance transporter, Bcr/CflA family | low | > 103 |
| Serratia liquefaciens MT49 | 0.50 | IAI46_24145 | | NAD(P)/FAD-dependent oxidoreductase | 0.16 | IAI46_17340 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 87 |
| Pantoea agglomerans CFBP13505 P0401 | 0.50 | PagCFBP13505_RS17875 | | NAD(P)/FAD-dependent oxidoreductase | 0.17 | PagCFBP13505_RS00675 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 74 |
| Pseudomonas sp. RS175 | 0.50 | PFR28_04173 | | hypothetical protein | 0.12 | PFR28_02357 | | Bicyclomycin resistance protein | low | > 88 |
| Erwinia amylovora T8 | 0.50 | OLJFJH_04505 | | aminoacetone oxidase family FAD-binding enzyme | 0.17 | OLJFJH_11715 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 58 |
| Dickeya dadantii 3937 | 0.50 | DDA3937_RS00340 | | NAD(P)/FAD-dependent oxidoreductase | 0.18 | DDA3937_RS09165 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 74 |
| Pseudomonas fluorescens FW300-N2C3 | 0.50 | AO356_13765 | | hypothetical protein | 0.13 | AO356_08050 | | MFS transporter | low | > 104 |
| Pseudomonas stutzeri RCH2 | 0.50 | Psest_0341 | | flavoprotein, HI0933 family | 0.11 | Psest_0741 | | drug resistance transporter, Bcr/CflA subfamily | low | > 67 |
| Pantoea sp. MT58 | 0.50 | IAI47_01370 | | NAD(P)/FAD-dependent oxidoreductase | 0.17 | IAI47_06590 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 76 |
| Klebsiella pneumoniae MKP103 | 0.50 | KDGMDA_07395 | | aminoacetone oxidase family FAD-binding enzyme | 0.16 | KDGMDA_26745 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 95 |
| Alteromonas macleodii MIT1002 | 0.49 | MIT1002_00118 | | N-methyltryptophan oxidase | 0.23 | MIT1002_04046 | | Sulfonamide resistance protein | low | > 70 |
| Enterobacter asburiae PDN3 | 0.49 | EX28DRAFT_4070 | | flavoprotein, HI0933 family | 0.15 | EX28DRAFT_0379 | | drug resistance transporter, Bcr/CflA subfamily | low | > 76 |
| Kangiella aquimarina DSM 16071 | 0.49 | B158DRAFT_1203 | | flavoprotein, HI0933 family | 0.12 | B158DRAFT_0826 | | drug resistance transporter, Bcr/CflA subfamily | low | > 40 |
| Lysobacter sp. OAE881 | 0.49 | ABIE51_RS09810 | | NAD(P)/FAD-dependent oxidoreductase | 0.13 | ABIE51_RS14645 | | multidrug effflux MFS transporter | low | > 62 |
| Klebsiella michiganensis M5al | 0.49 | BWI76_RS26565 | | membrane protein | 0.17 | BWI76_RS19805 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 92 |
| Marinobacter adhaerens HP15 | 0.49 | HP15_1033 | | flavoprotein, NADB Rossmann superfamily | 0.16 | HP15_3564 | | drug resistance transporter, Bcr/CflA subfamily | low | > 73 |
| Erwinia tracheiphila SCR3 | 0.49 | LU632_RS19445 | | NAD(P)/FAD-dependent oxidoreductase | 0.16 | LU632_RS17590 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 73 |
| Escherichia coli ECRC102 | 0.49 | NIAGMN_14210 | yhiN | Uncharacterized protein YhiN | 0.17 | NIAGMN_21130 | bcr | multidrug efflux MFS transporter Bcr | low | > 80 |
| Escherichia coli ECRC100 | 0.49 | OKFHMN_16445 | yhiN | Uncharacterized protein YhiN | 0.17 | OKFHMN_23365 | bcr | multidrug efflux MFS transporter Bcr | low | > 79 |
| Escherichia coli ECRC101 | 0.49 | MCAODC_06960 | yhiN | Uncharacterized protein YhiN | 0.17 | MCAODC_14415 | bcr | multidrug efflux MFS transporter Bcr | low | > 87 |
| Erwinia tracheiphila HP pepo 2.2 | 0.49 | IJEDHG_12610 | | aminoacetone oxidase family FAD-binding enzyme | 0.15 | IJEDHG_16040 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 61 |
| Pseudomonas sp. DMC3 | 0.49 | GFF143 | | putative protein | 0.13 | GFF3359 | | Bicyclomycin resistance protein | low | > 89 |
| Shewanella amazonensis SB2B | 0.49 | Sama_0064 | | hypothetical protein (RefSeq) | 0.12 | Sama_2017 | | bicyclomycin resistance protein (RefSeq) | low | > 62 |
| Escherichia coli ECRC99 | 0.49 | KEDOAH_11700 | yhiN | Uncharacterized protein YhiN | 0.17 | KEDOAH_04820 | bcr | multidrug efflux MFS transporter Bcr | — | — |
| Escherichia coli ECRC98 | 0.49 | JDDGAC_20075 | yhiN | Uncharacterized protein YhiN | 0.17 | JDDGAC_27325 | bcr | multidrug efflux MFS transporter Bcr | low | > 87 |
| Escherichia coli BL21 | 0.49 | ECD_03341 | | putative oxidoreductase | 0.17 | ECD_02112 | | bicyclomycin/cysteine/sulfonamide efflux transporter | low | > 61 |
| Enterobacter sp. TBS_079 | 0.49 | MPMX20_04392 | | hypothetical protein | 0.15 | MPMX20_03148 | | Bicyclomycin resistance protein | low | > 85 |
| Escherichia coli Nissle 1917 | 0.49 | ECOLIN_RS19955 | | NAD(P)/FAD-dependent oxidoreductase | 0.17 | ECOLIN_RS12755 | | multidrug efflux MFS transporter Bcr | low | > 55 |
| Pseudomonas fluorescens GW456-L13 | 0.49 | PfGW456L13_1077 | | FIG00953568: hypothetical protein | 0.12 | PfGW456L13_21 | | Multidrug resistance transporter, Bcr/CflA family | low | > 87 |
| Escherichia coli BW25113 | 0.49 | b3492 | yhiN | predicted oxidoreductase with FAD/NAD(P)-binding domain (NCBI) | 0.17 | b2182 | bcr | bicyclomycin/multidrug efflux system (NCBI) | low | > 76 |
| Pseudomonas fluorescens FW300-N2E3 | 0.49 | AO353_07855 | | hypothetical protein | 0.13 | AO353_17695 | | MFS transporter | low | > 101 |
| Escherichia fergusonii Becca | 0.49 | EFB2_00323 | | hypothetical protein | 0.17 | EFB2_01674 | | Bicyclomycin resistance protein | low | > 86 |
| Pseudomonas fluorescens SBW25 | 0.49 | PFLU_RS28025 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | PFLU_RS03255 | | multidrug effflux MFS transporter | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.49 | PFLU_RS28025 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | PFLU_RS03255 | | multidrug effflux MFS transporter | low | > 109 |
| Herbaspirillum seropedicae SmR1 | 0.49 | HSERO_RS04345 | | membrane protein | 0.15 | HSERO_RS23560 | | MFS transporter | low | > 78 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.49 | OHPLBJKB_00211 | | hypothetical protein | 0.17 | OHPLBJKB_01527 | | Bicyclomycin resistance protein | low | > 74 |
| Escherichia coli ECOR38 | 0.49 | HEPCGN_15360 | yhiN | Uncharacterized protein YhiN | 0.17 | HEPCGN_22630 | bcr | multidrug efflux MFS transporter Bcr | low | > 88 |
| Escherichia coli ECOR27 | 0.49 | NOLOHH_08380 | yhiN | Uncharacterized protein YhiN | 0.17 | NOLOHH_14940 | bcr | multidrug efflux MFS transporter Bcr | low | > 76 |
| Escherichia coli ECRC62 | 0.49 | BNILDI_03180 | yhiN | Uncharacterized protein YhiN | 0.17 | BNILDI_13860 | bcr | multidrug efflux MFS transporter Bcr | low | > 75 |
| Pseudomonas aeruginosa PA14 | 0.49 | IKLFDK_22630 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | IKLFDK_21300 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 98 |
| Vibrio cholerae E7946 ATCC 55056 | 0.49 | CSW01_00430 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | CSW01_08215 | | Bcr/CflA family drug resistance efflux transporter | low | > 62 |
| Pseudomonas simiae WCS417 | 0.48 | PS417_26375 | | membrane protein | 0.16 | PS417_11835 | | MFS transporter | low | > 88 |
| Pseudomonas lactucae CFBP13502 | 0.48 | GEMAOFIL_05401 | | hypothetical protein | 0.14 | GEMAOFIL_02984 | | Bicyclomycin resistance protein | low | > 96 |
| Pseudomonas aeruginosa MRSN321 | 0.48 | DY961_RS22815 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | DY961_RS28160 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 100 |
| Pseudomonas orientalis W4I3 | 0.48 | QF045_RS00760 | | NAD(P)/FAD-dependent oxidoreductase | 0.16 | QF045_RS16180 | | multidrug effflux MFS transporter | low | > 93 |
| Pseudomonas aeruginosa PUPa3 | 0.48 | DQ20_RS36525 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | DQ20_RS47480 | | Bcr/CflA family multidrug efflux MFS transporter | low | > 101 |
| Pseudomonas fluorescens FW300-N1B4 | 0.48 | Pf1N1B4_2411 | | FIG00953568: hypothetical protein | 0.11 | Pf1N1B4_1259 | | Multidrug resistance transporter, Bcr/CflA family | low | > 87 |
| Dyella japonica UNC79MFTsu3.2 | 0.48 | ABZR86_RS00415 | | NAD(P)/FAD-dependent oxidoreductase | 0.17 | ABZR86_RS00225 | | multidrug effflux MFS transporter | low | > 74 |
| Rhodanobacter denitrificans MT42 | 0.48 | LRK55_RS14395 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | LRK55_RS14135 | | multidrug effflux MFS transporter | low | > 63 |
| Pseudomonas segetis P6 | 0.48 | MPMX49_00673 | | hypothetical protein | 0.13 | MPMX49_01117 | | Bicyclomycin resistance protein | low | > 75 |
| Pseudomonas syringae pv. syringae B728a | 0.47 | Psyr_0515 | | HI0933-like protein | 0.13 | Psyr_0657 | | Drug resistance transporter Bcr/CflA subfamily | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.47 | Psyr_0515 | | HI0933-like protein | 0.13 | Psyr_0657 | | Drug resistance transporter Bcr/CflA subfamily | low | > 86 |
| Shewanella loihica PV-4 | 0.47 | Shew_3802 | | hypothetical protein (RefSeq) | 0.12 | Shew_1777 | | Bcr/CflA subfamily drug resistance transporter (RefSeq) | — | — |
| Shewanella sp. ANA-3 | 0.47 | Shewana3_0055 | | hypothetical protein (RefSeq) | 0.13 | Shewana3_2268 | | Bcr/CflA subfamily drug resistance transporter (RefSeq) | low | > 73 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.47 | A4249_RS12180 | | NAD(P)/FAD-dependent oxidoreductase | 0.42 | A4249_RS14555 | | multidrug effflux MFS transporter | low | > 48 |
| Pseudomonas sp. SVBP6 | 0.47 | COO64_RS17615 | | NAD(P)/FAD-dependent oxidoreductase | 0.12 | COO64_RS26355 | | multidrug effflux MFS transporter | low | > 93 |
| Rhodanobacter denitrificans FW104-10B01 | 0.47 | LRK54_RS14680 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | LRK54_RS14420 | | multidrug effflux MFS transporter | low | > 59 |
| Shewanella oneidensis MR-1 | 0.46 | SO0054 | | conserved hypothetical protein TIGR00275 (NCBI ptt file) | 0.12 | SO2280 | | bicyclomycin resistance protein (NCBI ptt file) | low | > 76 |
| Pseudomonas putida KT2440 | 0.46 | PP_4953 | | putative oxidoreductase with FAD/NAD(P)-binding domain | 0.14 | PP_0589 | | Bcr/CflA family multidrug resistance transporter | low | > 96 |
| Pseudomonas sp. BP01 | 0.46 | JOY50_RS09930 | | NAD(P)/FAD-dependent oxidoreductase | 0.13 | JOY50_RS23280 | | multidrug effflux MFS transporter | low | > 84 |
| Cupriavidus basilensis FW507-4G11 | 0.46 | RR42_RS14990 | | membrane protein | 0.15 | RR42_RS28940 | | Bcr/CflA family drug resistance efflux transporter | low | > 128 |
| Paraburkholderia sabiae LMG 24235 | 0.46 | QEN71_RS15210 | | NAD(P)/FAD-dependent oxidoreductase | 0.13 | QEN71_RS38440 | | multidrug effflux MFS transporter | low | > 153 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.46 | GFF3659 | | NAD(FAD)-utilizing dehydrogenases | 0.09 | GFF5490 | | Multidrug resistance transporter, Bcr/CflA family | — | — |
| Paraburkholderia graminis OAS925 | 0.46 | ABIE53_004862 | | putative Rossmann fold flavoprotein | 0.17 | ABIE53_005658 | | DHA1 family bicyclomycin/chloramphenicol resistance-like MFS transporter | low | > 113 |
| Variovorax sp. SCN45 | 0.46 | GFF4713 | | Uncharacterized protein YhiN | 0.16 | GFF1385 | | Multidrug resistance transporter, Bcr/CflA family | low | > 127 |
| Ralstonia sp. UNC404CL21Col | 0.46 | ABZR87_RS15620 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | ABZR87_RS15340 | | multidrug effflux MFS transporter | low | > 80 |
| Ralstonia solanacearum PSI07 | 0.46 | RPSI07_RS13540 | | NAD(P)/FAD-dependent oxidoreductase | 0.15 | RPSI07_RS00615 | | MFS transporter | low | > 81 |
| Pseudomonas sp. S08-1 | 0.46 | OH686_10655 | | Uncharacterized protein YhiN | 0.14 | OH686_07365 | | Multidrug resistance transporter, Bcr/CflA family | low | > 80 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.46 | H281DRAFT_06012 | | hypothetical protein | 0.13 | H281DRAFT_04016 | | MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein | low | > 103 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.46 | Xcc-8004.2264.1 | | FIG01211838: hypothetical protein | 0.13 | Xcc-8004.3876.1 | | MFS transporter | low | > 74 |
| Dinoroseobacter shibae DFL-12 | 0.45 | Dshi_2710 | | HI0933 family protein (RefSeq) | 0.25 | Dshi_1559 | | drug resistance transporter, Bcr/CflA subfamily (RefSeq) | low | > 64 |
| Ralstonia solanacearum GMI1000 | 0.44 | RS_RS11135 | | NAD(P)/FAD-dependent oxidoreductase | 0.14 | RS_RS01070 | | MFS transporter | 0.23 | 78 |
| Acidovorax sp. GW101-3H11 | 0.44 | Ac3H11_3253 | | NAD(FAD)-utilizing dehydrogenases | 0.12 | Ac3H11_1673 | | MFS transporter | low | > 79 |
| Ralstonia solanacearum IBSBF1503 | 0.44 | RALBFv3_RS03690 | | NAD(P)/FAD-dependent oxidoreductase | 0.16 | RALBFv3_RS22540 | | Bcr/CflA family drug resistance efflux transporter | low | > 76 |
| Ralstonia solanacearum UW163 | 0.44 | UW163_RS09980 | | NAD(P)/FAD-dependent oxidoreductase | 0.16 | UW163_RS23085 | | Bcr/CflA family drug resistance efflux transporter | — | — |
| Variovorax sp. OAS795 | 0.42 | ABID97_RS20650 | | NAD(P)/FAD-dependent oxidoreductase | 0.12 | ABID97_RS10530 | | multidrug effflux MFS transporter | low | > 91 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.40 | CA265_RS07750 | | aminoacetone oxidase family FAD-binding enzyme | 0.18 | CA265_RS08155 | | Bcr/CflA family drug resistance efflux transporter | low | > 88 |
| Acinetobacter baumannii LAC-4 | 0.39 | RR41_RS15405 | | NAD(P)/FAD-dependent oxidoreductase | 0.28 | RR41_RS04705 | | multidrug effflux MFS transporter | low | > 55 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.38 | ABZR88_RS09315 | | NAD(P)/FAD-dependent oxidoreductase | 0.15 | ABZR88_RS13175 | | multidrug effflux MFS transporter | 0.31 | 61 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.16 | Echvi_3335 | | flavoprotein, HI0933 family | 0.16 | Echvi_3352 | | drug resistance transporter, Bcr/CflA subfamily | low | > 79 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.15 | CA264_05900 | | aminoacetone oxidase family FAD-binding enzyme | 0.17 | CA264_01830 | | Bcr/CflA family drug resistance efflux transporter | low | > 74 |
| Cellulophaga baltica 18 | 0.13 | M666_RS02740 | | NAD(P)/FAD-dependent oxidoreductase | 0.28 | M666_RS11150 | | multidrug effflux MFS transporter | low | > 67 |
| Azospirillum sp. SherDot2 | 0.10 | MPMX19_00024 | | 3-dehydro-bile acid delta(4,6)-reductase | 0.17 | MPMX19_06022 | | Bicyclomycin resistance protein | low | > 112 |
| Rhodopseudomonas palustris CGA009 | 0.09 | TX73_011285 | | NAD(P)/FAD-dependent oxidoreductase | 0.10 | TX73_018225 | | multidrug effflux MFS transporter | low | > 86 |
| Azospirillum brasilense Sp245 | 0.09 | AZOBR_RS02525 | | NAD(FAD)-utilizing dehydrogenase | 0.11 | AZOBR_RS00095 | | MFS transporter permease | low | > 97 |
Not shown: 8 genomes with orthologs for GFF1279 only; 7 genomes with orthologs for GFF3351 only