Conservation of cofitness between ECD_04103 and ECD_04047 in Escherichia coli BL21

82 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_04103 putative antibiotic peptide MccB17 maturation peptidase 1.0 ECD_04047 23S rRNA mG2251 2'-O-ribose methyltransferase, SAM-dependent 0.75 2
Escherichia coli ECRC62 1.00 BNILDI_07325 pmbA metalloprotease PmbA 1.00 BNILDI_07010 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 75
Escherichia coli ECOR38 1.00 HEPCGN_10125 pmbA metalloprotease PmbA 1.00 HEPCGN_10445 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 87
Escherichia coli ECRC100 1.00 OKFHMN_11925 pmbA metalloprotease PmbA 1.00 OKFHMN_12215 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 80
Escherichia coli ECRC99 1.00 KEDOAH_16230 pmbA metalloprotease PmbA 1.00 KEDOAH_15940 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB
Escherichia coli ECRC98 1.00 JDDGAC_15565 pmbA metalloprotease PmbA 1.00 JDDGAC_15855 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03800 Metalloprotease PmbA 1.00 OHPLBJKB_03862 '23S rRNA (guanosine-2'-O-)-methyltransferase RlmB' transl_table=11 low > 73
Escherichia coli BW25113 1.00 b4235 pmbA predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) 1.00 b4180 rlmB 23S rRNA (Gm2251)-methyltransferase (NCBI) low > 76
Escherichia coli ECRC101 1.00 MCAODC_02430 pmbA metalloprotease PmbA 1.00 MCAODC_02730 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 87
Escherichia coli ECRC102 1.00 NIAGMN_09775 pmbA metalloprotease PmbA 1.00 NIAGMN_10065 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB
Escherichia coli ECOR27 1.00 NOLOHH_04185 pmbA metalloprotease PmbA 1.00 NOLOHH_04480 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 75
Escherichia fergusonii Becca 0.99 EFB2_04298 Metalloprotease PmbA 1.00 EFB2_04355 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS24570 metalloprotease PmbA 1.00 ECOLIN_RS24270 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 55
Enterobacter sp. TBS_079 0.96 MPMX20_00517 Metalloprotease PmbA 0.96 MPMX20_00461 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF904 TldE protein, part of TldE/TldD proteolytic complex 0.97 GFF833 '23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-)' transl_table=11 low > 78
Enterobacter asburiae PDN3 0.96 EX28DRAFT_3422 Predicted Zn-dependent proteases and their inactivated homologs 0.97 EX28DRAFT_3377 rRNA methylase, putative, group 3 low > 76
Klebsiella michiganensis M5al 0.94 BWI76_RS02850 metalloprotease PmbA 0.96 BWI76_RS02580 23S rRNA (guanosine(2251)-2'-O)-methyltransferase low > 92
Serratia liquefaciens MT49 0.86 IAI46_22575 metalloprotease PmbA 0.87 IAI46_01665 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 86
Rahnella sp. WP5 0.85 EX31_RS12320 metalloprotease PmbA 0.85 EX31_RS08780 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 89
Pectobacterium carotovorum WPP14 0.84 HER17_RS20090 metalloprotease PmbA 0.84 HER17_RS03840 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 75
Pantoea sp. MT58 0.84 IAI47_02765 metalloprotease PmbA 0.87 IAI47_02630 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 76
Dickeya dadantii 3937 0.81 DDA3937_RS01500 metalloprotease PmbA 0.87 DDA3937_RS17255 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 74
Erwinia tracheiphila SCR3 0.81 LU632_RS02145 pmbA metalloprotease PmbA 0.85 LU632_RS21745 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 74
Dickeya dianthicola 67-19 0.81 HGI48_RS01415 metalloprotease PmbA 0.87 HGI48_RS17310 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB
Dickeya dianthicola ME23 0.81 DZA65_RS01480 metalloprotease PmbA 0.86 DZA65_RS18400 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 75
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_12845 metalloprotease PmbA 0.73 CSW01_13150 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 62
Shewanella sp. ANA-3 0.59 Shewana3_3631 microcin-processing peptidase 1 (RefSeq) 0.66 Shewana3_0698 23S rRNA (guanosine-2'-O-)-methyltransferase (RefSeq) low > 73
Shewanella amazonensis SB2B 0.59 Sama_0482 PmbA protein (RefSeq) 0.66 Sama_3066 23S rRNA (guanosine-2'-O-)-methyltransferase (RefSeq) low > 62
Shewanella oneidensis MR-1 0.59 SO4078 pmbA pmba protein (NCBI ptt file) 0.67 SO3934 RNA methyltransferase, TrmH family, group 3 (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.57 Shew_0416 peptidase U62, modulator of DNA gyrase (RefSeq) 0.63 Shew_3288 23S rRNA (guanosine-2'-O-)-methyltransferase (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.54 MIT1002_00230 peptidase PmbA 0.65 MIT1002_03605 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB low > 70
Pseudomonas sp. RS175 0.48 PFR28_00163 Metalloprotease PmbA 0.57 PFR28_05131 '23S rRNA (guanosine-2'-O-)-methyltransferase RlmB' transl_table=11 low > 88
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_3278 TldE protein, part of TldE/TldD proteolytic complex 0.57 Pf6N2E2_3606 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) low > 103
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS04350 metalloprotease PmbA 0.56 PFLU_RS02630 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 109
Pseudomonas fluorescens SBW25 0.48 PFLU_RS04350 metalloprotease PmbA 0.56 PFLU_RS02630 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 109
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_07085 peptidase PmbA 0.57 AO356_08605 23S rRNA methyltransferase low > 104
Pseudomonas simiae WCS417 0.47 PS417_04295 peptidase PmbA 0.56 PS417_02560 23S rRNA methyltransferase low > 88
Pseudomonas putida KT2440 0.47 PP_0942 regulatory protease 0.56 PP_4879 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB low > 96
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_1090 TldE protein, part of TldE/TldD proteolytic complex 0.57 Pf1N1B4_1402 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) low > 87
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_05205 peptidase PmbA 0.57 AO353_13205 23S rRNA methyltransferase low > 101
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_5024 TldE protein, part of TldE/TldD proteolytic complex 0.57 PfGW456L13_143 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.57 Psyr_0580 23S rRNA Gm-2251 2'-O-methyltransferase low > 86
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.57 Psyr_0580 23S rRNA Gm-2251 2'-O-methyltransferase low > 86
Pseudomonas stutzeri RCH2 0.45 Psest_3318 Predicted Zn-dependent proteases and their inactivated homologs 0.57 Psest_0692 rRNA methylase, putative, group 3 0.40 36
Herbaspirillum seropedicae SmR1 0.45 HSERO_RS09265 peptidase C69 0.50 HSERO_RS09295 23S rRNA (guanosine-2'-O-)-methyltransferase low > 78
Xanthomonas campestris pv. campestris strain 8004 0.45 Xcc-8004.1885.1 TldE protein, part of TldE/TldD proteolytic complex 0.46 Xcc-8004.3368.1 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) low > 74
Variovorax sp. OAS795 0.45 ABID97_RS20695 metalloprotease PmbA 0.49 ABID97_RS14320 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 91
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS21700 metalloprotease PmbA 0.46 ABZR86_RS08265 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 74
Pseudomonas sp. S08-1 0.45 OH686_08570 TldE protein, part of TldE/TldD proteolytic complex 0.60 OH686_15915 23S rRNA (guanosine(2251)-2'-O)-methyltransferase low > 80
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_10260 pmbA metalloprotease PmbA 0.43 OKGIIK_06760 rlmB 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 52
Variovorax sp. SCN45 0.45 GFF4697 TldE protein, part of TldE/TldD proteolytic complex 0.49 GFF1018 23S rRNA (guanosine(2251)-2'-O)-methyltransferase (EC 2.1.1.185) low > 127
Rhodanobacter denitrificans MT42 0.44 LRK55_RS03125 metalloprotease PmbA 0.45 LRK55_RS00230 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 63
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS03375 metalloprotease PmbA 0.45 LRK54_RS00490 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 59
Dechlorosoma suillum PS 0.44 Dsui_1234 putative Zn-dependent protease-like protein 0.48 Dsui_1899 rRNA methylase, putative, group 3 low > 51
Acidovorax sp. GW101-3H11 0.44 Ac3H11_3262 TldE protein, part of TldE/TldD proteolytic complex 0.49 Ac3H11_4141 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) low > 79
Ralstonia solanacearum UW163 0.43 UW163_RS15845 metalloprotease PmbA 0.53 UW163_RS12815 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB
Ralstonia solanacearum IBSBF1503 0.43 RALBFv3_RS13965 metalloprotease PmbA 0.53 RALBFv3_RS15350 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS09660 metalloprotease PmbA 0.52 ABZR87_RS10990 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 80
Paraburkholderia graminis OAS925 0.43 ABIE53_003116 PmbA protein 0.51 ABIE53_001941 23S rRNA (guanosine2251-2'-O)-methyltransferase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_04304 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.51 H281DRAFT_00713 23S rRNA Gm-2251 2'-O-methyltransferase low > 103
Ralstonia solanacearum PSI07 0.43 RPSI07_RS19505 metalloprotease PmbA 0.52 RPSI07_RS18025 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 81
Kangiella aquimarina DSM 16071 0.43 B158DRAFT_2075 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.58 B158DRAFT_1990 23S rRNA Gm-2251 2'-O-methyltransferase (EC 2.1.1.185) low > 40
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS04270 metalloprotease PmbA 0.52 QEN71_RS22920 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB 0.75 102
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS14705 peptidase C69 0.52 BPHYT_RS08460 23S rRNA (guanosine-2'-O-)-methyltransferase
Castellaniella sp019104865 MT123 0.42 ABCV34_RS10610 metalloprotease PmbA 0.52 ABCV34_RS06630 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF3655 TldE protein, part of TldE/TldD proteolytic complex 0.48 GFF4838 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) low > 90
Lysobacter sp. OAE881 0.41 ABIE51_RS06805 metalloprotease PmbA 0.45 ABIE51_RS07480 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 62
Ralstonia solanacearum GMI1000 0.41 RS_RS04700 metalloprotease PmbA 0.52 RS_RS06160 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 80
Cupriavidus basilensis FW507-4G11 0.41 RR42_RS14750 peptidase PMbA 0.49 RR42_RS13060 23S rRNA methyltransferase low > 128
Azospirillum brasilense Sp245 0.34 AZOBR_RS11930 modulator protein 0.33 AZOBR_RS11565 ribosomal large subunit pseudouridine synthase low > 97
Azospirillum sp. SherDot2 0.34 MPMX19_01886 Metalloprotease PmbA 0.31 MPMX19_00374 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB
Sphingomonas koreensis DSMZ 15582 0.30 Ga0059261_0810 Predicted Zn-dependent proteases and their inactivated homologs 0.25 Ga0059261_1814 rRNA methylase, putative, group 3 low > 68
Magnetospirillum magneticum AMB-1 0.29 AMB_RS22120 TldD/PmbA family protein 0.34 AMB_RS15870 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB
Rhodopseudomonas palustris CGA009 0.29 TX73_005930 TldD/PmbA family protein 0.25 TX73_017390 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 86
Caulobacter crescentus NA1000 0.28 CCNA_00311 Zn-dependent protease family protein 0.26 CCNA_01297 23S rRNA Gm2251 methyltransferase low > 66
Caulobacter crescentus NA1000 Δfur 0.28 CCNA_00311 Zn-dependent protease family protein 0.26 CCNA_01297 23S rRNA Gm2251 methyltransferase low > 67
Phaeobacter inhibens DSM 17395 0.27 PGA1_c33480 protein PmbA 0.24 PGA1_c09200 putative 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB
Dinoroseobacter shibae DFL-12 0.26 Dshi_0064 peptidase U62 modulator of DNA gyrase (RefSeq) 0.23 Dshi_2571 RNA methyltransferase, TrmH family, group 3 (RefSeq) low > 64
Bacteroides thetaiotaomicron VPI-5482 0.20 BT3649 putative modulator of DNA gyrase (NCBI ptt file) 0.28 BT1360 tRNA/rRNA methyltransferase (NCBI ptt file)
Bacteroides stercoris CC31F 0.17 HMPREF1181_RS03170 TldD/PmbA family protein 0.28 HMPREF1181_RS10895 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 56
Parabacteroides merdae CL09T00C40 0.16 HMPREF1078_RS03625 TldD/PmbA family protein 0.26 HMPREF1078_RS02015 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 61
Pedobacter sp. GW460-11-11-14-LB5 0.06 CA265_RS02445 peptidase C69 0.29 CA265_RS08890 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 88
Pontibacter actiniarum KMM 6156, DSM 19842 0.06 CA264_16645 peptidase C69 0.25 CA264_20095 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB low > 74

Not shown: 6 genomes with orthologs for ECD_04103 only; 9 genomes with orthologs for ECD_04047 only