Conservation of cofitness between ECD_02776 and ECD_02484 in Escherichia coli BL21

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_02776 16S rRNA m(3)U1498 methyltransferase, SAM-dependent 1.0 ECD_02484 23S rRNA pseudouridine(1911,1915,1917) synthase 0.78 4
Escherichia coli ECOR38 1.00 HEPCGN_18585 Ribosomal RNA small subunit methyltransferase E 1.00 HEPCGN_20375 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 87
Escherichia coli ECRC102 1.00 NIAGMN_17045 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 1.00 NIAGMN_19020 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS16390 16S rRNA (uracil(1498)-N(3))-methyltransferase 1.00 ECOLIN_RS14675 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 55
Escherichia fergusonii Becca 1.00 EFB2_00956 Ribosomal RNA small subunit methyltransferase E 1.00 EFB2_01296 Ribosomal large subunit pseudouridine synthase D low > 86
Escherichia coli ECOR27 1.00 NOLOHH_11150 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 1.00 NOLOHH_12925 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 75
Escherichia coli ECRC99 1.00 KEDOAH_08860 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 1.00 KEDOAH_06970 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD — —
Escherichia coli ECRC101 1.00 MCAODC_09800 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 1.00 MCAODC_11780 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00772 Ribosomal RNA small subunit methyltransferase E 1.00 OHPLBJKB_01112 Ribosomal large subunit pseudouridine synthase D 0.42 32
Escherichia coli ECRC98 1.00 JDDGAC_22910 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 1.00 JDDGAC_24915 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 86
Escherichia coli BW25113 1.00 b2946 yggJ orf, hypothetical protein (VIMSS) 1.00 b2594 rluD 23S rRNA pseudouridine synthase (NCBI) — —
Escherichia coli ECRC100 1.00 OKFHMN_19280 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 1.00 OKFHMN_21250 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD 0.53 44
Escherichia coli ECRC62 1.00 BNILDI_09730 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 1.00 BNILDI_11730 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF3048 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.95 GFF4182 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) low > 78
Enterobacter asburiae PDN3 0.89 EX28DRAFT_2984 RNA methyltransferase, RsmE family 0.94 EX28DRAFT_2695 pseudouridine synthase, RluA family low > 76
Enterobacter sp. TBS_079 0.89 MPMX20_03804 Ribosomal RNA small subunit methyltransferase E 0.93 MPMX20_03463 Ribosomal large subunit pseudouridine synthase D low > 85
Klebsiella michiganensis M5al 0.86 BWI76_RS24070 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.93 BWI76_RS21450 23S rRNA pseudouridine(1911/1915/1917) synthase low > 92
Rahnella sp. WP5 0.85 EX31_RS02660 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.83 EX31_RS07570 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 89
Serratia liquefaciens MT49 0.83 IAI46_21385 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.88 IAI46_03985 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 86
Pantoea sp. MT58 0.82 IAI47_03620 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.87 IAI47_04425 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 76
Dickeya dadantii 3937 0.81 DDA3937_RS18555 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.87 DDA3937_RS16110 23S rRNA pseudouridine(1911/1915/1917) synthase RluD 0.58 2
Dickeya dianthicola 67-19 0.79 HGI48_RS18490 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.85 HGI48_RS16235 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 71
Dickeya dianthicola ME23 0.79 DZA65_RS19625 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.85 DZA65_RS17330 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 75
Erwinia tracheiphila SCR3 0.79 LU632_RS05485 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.85 LU632_RS16945 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 74
Pectobacterium carotovorum WPP14 0.78 HER17_RS02640 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.85 HER17_RS05400 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 75
Shewanella sp. ANA-3 0.68 Shewana3_3444 16S ribosomal RNA methyltransferase RsmE (RefSeq) 0.66 Shewana3_3171 ribosomal large subunit pseudouridine synthase D (RefSeq) low > 73
Vibrio cholerae E7946 ATCC 55056 0.68 CSW01_02495 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.70 CSW01_03695 ribosomal large subunit pseudouridine synthase D low > 62
Shewanella amazonensis SB2B 0.66 Sama_0575 16S ribosomal RNA methyltransferase RsmE (RefSeq) 0.62 Sama_2605 pseudouridylate synthase (RefSeq) — —
Shewanella loihica PV-4 0.65 Shew_3224 hypothetical protein (RefSeq) 0.64 Shew_2950 RluA family pseudouridine synthase (RefSeq) 0.57 14
Marinobacter adhaerens HP15 0.46 HP15_2926 ribosomal RNA small subunit methyltransferase E 0.52 HP15_527 pseudouridine synthase, RluA family low > 73
Alteromonas macleodii MIT1002 0.45 MIT1002_03054 Ribosomal RNA small subunit methyltransferase E 0.63 MIT1002_02679 Ribosomal large subunit pseudouridine synthase D low > 70
Kangiella aquimarina DSM 16071 0.43 B158DRAFT_0180 RNA methyltransferase, RsmE family 0.55 B158DRAFT_2532 Pseudouridylate synthases, 23S RNA-specific low > 40
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_08050 16S rRNA methyltransferase 0.54 AO353_14220 ribosomal large subunit pseudouridine synthase D low > 101
Pseudomonas sp. RS175 0.42 PFR28_04209 Ribosomal RNA small subunit methyltransferase E 0.53 PFR28_03748 Ribosomal large subunit pseudouridine synthase D 0.29 33
Pseudomonas fluorescens SBW25 0.42 PFLU_RS28200 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.54 PFLU_RS03870 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 109
Pseudomonas fluorescens SBW25-INTG 0.42 PFLU_RS28200 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.54 PFLU_RS03870 23S rRNA pseudouridine(1911/1915/1917) synthase RluD 0.27 20
Pseudomonas putida KT2440 0.41 PP_4985 16S rRNA m3U1498 methyltransferase 0.54 PP_0623 23S rRNA pseudouridine(1911,1915,1917) synthase — —
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_4630 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.54 Pf6N2E2_5127 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) — —
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_13565 16S rRNA methyltransferase 0.54 AO356_15925 ribosomal large subunit pseudouridine synthase D 0.38 2
Pseudomonas fluorescens GW456-L13 0.41 PfGW456L13_1043 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.53 PfGW456L13_1493 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) — —
Pseudomonas simiae WCS417 0.41 PS417_26545 16S rRNA methyltransferase 0.54 PS417_03820 ribosomal large subunit pseudouridine synthase D — —
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_2376 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.53 Pf1N1B4_2822 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) — —
Pseudomonas stutzeri RCH2 0.40 Psest_0305 RNA methyltransferase, RsmE family 0.53 Psest_0709 pseudouridine synthase, RluA family 0.30 3
Pseudomonas syringae pv. syringae B728a 0.40 Psyr_0453 16S rRNA m(3)U-1498 methyltransferase 0.53 Psyr_0726 ribosomal large subunit pseudouridine synthase D 0.48 2
Pseudomonas syringae pv. syringae B728a ΔmexB 0.40 Psyr_0453 16S rRNA m(3)U-1498 methyltransferase 0.53 Psyr_0726 ribosomal large subunit pseudouridine synthase D low > 86
Pseudomonas sp. S08-1 0.39 OH686_10855 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.54 OH686_16410 LSU rRNA pseudouridine(1911/1915/1917) synthase low > 80
Dyella japonica UNC79MFTsu3.2 0.38 ABZR86_RS10230 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.51 ABZR86_RS10965 23S rRNA pseudouridine(1911/1915/1917) synthase RluD 0.44 14
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.1558.1 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.52 Xcc-8004.1362.1 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) — —
Rhodanobacter denitrificans FW104-10B01 0.36 LRK54_RS04160 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.51 LRK54_RS04965 23S rRNA pseudouridine(1911/1915/1917) synthase RluD 0.77 7
Acinetobacter radioresistens SK82 0.35 MPMX26_01001 Ribosomal RNA small subunit methyltransferase E 0.44 MPMX26_00735 Ribosomal large subunit pseudouridine synthase D low > 36
Rhodanobacter denitrificans MT42 0.35 LRK55_RS03930 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.51 LRK55_RS04745 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 63
Lysobacter sp. OAE881 0.35 ABIE51_RS05260 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.52 ABIE51_RS04885 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 62
Ralstonia solanacearum IBSBF1503 0.34 RALBFv3_RS05880 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.40 RALBFv3_RS01520 RluA family pseudouridine synthase low > 76
Ralstonia solanacearum UW163 0.34 UW163_RS07745 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.40 UW163_RS14830 RluA family pseudouridine synthase — —
Ralstonia solanacearum PSI07 0.34 RPSI07_RS11365 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.41 RPSI07_RS15970 RluA family pseudouridine synthase low > 81
Rhodanobacter sp. FW510-T8 0.33 OKGIIK_11035 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.49 OKGIIK_01790 rluD 23S rRNA pseudouridine(1911/1915/1917) synthase RluD low > 52
Ralstonia sp. UNC404CL21Col 0.33 ABZR87_RS01505 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.40 ABZR87_RS13315 RluA family pseudouridine synthase low > 80
Ralstonia solanacearum GMI1000 0.33 RS_RS13825 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.41 RS_RS08205 RluA family pseudouridine synthase low > 80
Acidovorax sp. GW101-3H11 0.32 Ac3H11_4323 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.32 Ac3H11_1787 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) low > 79
Variovorax sp. SCN45 0.30 GFF3255 16S rRNA (uracil(1498)-N(3))-methyltransferase (EC 2.1.1.193) 0.31 GFF988 LSU rRNA pseudouridine(1911/1915/1917) synthase (EC 5.4.99.23) low > 127
Herbaspirillum seropedicae SmR1 0.29 HSERO_RS07110 16S rRNA methyltransferase 0.37 HSERO_RS15070 ribosomal large subunit pseudouridine synthase D low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.29 GFF2462 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.34 GFF4870 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) low > 90
Castellaniella sp019104865 MT123 0.27 ABCV34_RS15445 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.33 ABCV34_RS01885 RluA family pseudouridine synthase 0.92 29
Pedobacter sp. GW460-11-11-14-LB5 0.20 CA265_RS23620 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.27 CA265_RS14415 pseudouridine synthase 0.44 13
Bacteroides thetaiotaomicron VPI-5482 0.20 BT4328 conserved hypothetical protein (NCBI ptt file) 0.30 BT3712 ribosomal large subunit pseudouridine synthase D (NCBI ptt file) low > 81
Phaeobacter inhibens DSM 17395 0.19 PGA1_c02950 RNA methyltransferase-like protein 0.33 PGA1_c09000 ribosomal large subunit pseudouridine synthase D low > 62
Bacteroides ovatus ATCC 8483 0.19 BACOVA_05130 RNA methyltransferase, RsmE family 0.30 BACOVA_03528 pseudouridine synthase, RluA family 0.52 9
Pontibacter actiniarum KMM 6156, DSM 19842 0.19 CA264_05265 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.28 CA264_15205 RNA pseudouridine synthase low > 74
Dinoroseobacter shibae DFL-12 0.18 Dshi_3099 protein of unknown function DUF558 (RefSeq) 0.27 Dshi_2610 pseudouridine synthase, RluA family (RefSeq) low > 64
Parabacteroides merdae CL09T00C40 0.18 HMPREF1078_RS10135 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.27 HMPREF1078_RS12640 RluA family pseudouridine synthase low > 61
Azospirillum sp. SherDot2 0.18 MPMX19_00577 Ribosomal RNA small subunit methyltransferase E 0.33 MPMX19_05442 Ribosomal large subunit pseudouridine synthase D low > 112
Fusobacterium nucleatum SB010 0.18 HUW76_04180 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.31 HUW76_08575 RluA family pseudouridine synthase low > 35
Rhodopseudomonas palustris CGA009 0.17 TX73_005910 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.34 TX73_001905 RluA family pseudouridine synthase low > 86
Bacteroides stercoris CC31F 0.17 HMPREF1181_RS05940 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.29 HMPREF1181_RS03250 RluA family pseudouridine synthase low > 56
Rhizobium sp. OAE497 0.17 ABIE40_RS03520 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.33 ABIE40_RS14790 RluA family pseudouridine synthase low > 107
Agrobacterium fabrum C58 0.17 Atu0657 hypothetical protein 0.32 Atu2443 ribosomal large subunit pseudouridine synthase, RluD subfamily — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.17 Echvi_3055 RNA methyltransferase, RsmE family 0.30 Echvi_0642 pseudouridine synthase, RluA family low > 79
Bosea sp. OAE506 0.16 ABIE41_RS23100 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.29 ABIE41_RS05635 RluA family pseudouridine synthase low > 77
Sinorhizobium meliloti 1021 0.16 SMc00826 16S ribosomal RNA methyltransferase RsmE 0.31 SMc00647 ribosomal large subunit pseudouridine synthase 0.36 19
Mucilaginibacter yixingensis YX-36 DSM 26809 0.16 ABZR88_RS17085 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.28 ABZR88_RS03985 RluA family pseudouridine synthase low > 71
Sphingomonas koreensis DSMZ 15582 0.16 Ga0059261_0807 RNA methyltransferase, RsmE family 0.35 Ga0059261_0664 pseudouridine synthase, RluA family low > 68
Caulobacter crescentus NA1000 Δfur 0.16 CCNA_03528 RNA methyltransferase 0.30 CCNA_00485 ribosomal large subunit pseudouridine synthase D low > 67
Caulobacter crescentus NA1000 0.16 CCNA_03528 RNA methyltransferase 0.30 CCNA_00485 ribosomal large subunit pseudouridine synthase D 0.70 1
Phocaeicola dorei CL03T12C01 0.16 ABI39_RS18150 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.30 ABI39_RS02845 RluA family pseudouridine synthase low > 72
Phocaeicola vulgatus CL09T03C04 0.16 HMPREF1058_RS05940 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.30 HMPREF1058_RS08615 RluA family pseudouridine synthase low > 67
Magnetospirillum magneticum AMB-1 0.15 AMB_RS01240 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.31 AMB_RS16095 RluA family pseudouridine synthase low > 64
Mycobacterium tuberculosis H37Rv 0.15 Rv2372c Conserved hypothetical protein 0.22 Rv1540 Conserved hypothetical protein member of yabO/yceC/yfiI family — —
Synechococcus elongatus PCC 7942 0.14 Synpcc7942_0806 hypothetical protein 0.32 Synpcc7942_1112 ribosomal large subunit pseudouridine synthase D low > 38
Brevundimonas sp. GW460-12-10-14-LB2 0.13 A4249_RS00350 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.26 A4249_RS10060 RluA family pseudouridine synthase — —
Rhodospirillum rubrum S1H 0.13 Rru_A0571 hypothetical protein (NCBI) 0.33 Rru_A1111 Pseudouridine synthase, RluD (NCBI) 0.86 2
Bifidobacterium breve UCC2003 0.11 BBR_RS15150 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.20 BBR_RS17135 RluA family pseudouridine synthase low > 34

Not shown: 9 genomes with orthologs for ECD_02776 only; 3 genomes with orthologs for ECD_02484 only