Conservation of cofitness between CSW01_12495 and CSW01_12600 in Vibrio cholerae E7946 ATCC 55056

98 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12495 L-aspartate oxidase 1.0 CSW01_12600 3-isopropylmalate dehydrogenase 0.60 8
Shewanella amazonensis SB2B 0.75 Sama_0873 L-aspartate oxidase (RefSeq) 0.69 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) — —
Shewanella sp. ANA-3 0.74 Shewana3_3033 L-aspartate oxidase (RefSeq) 0.71 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) — —
Shewanella oneidensis MR-1 0.74 SO1341 nadB L-aspartate oxidase (NCBI ptt file) 0.71 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.37 71
Enterobacter asburiae PDN3 0.74 EX28DRAFT_0071 L-aspartate oxidase (EC 1.4.3.16) 0.77 EX28DRAFT_3669 3-isopropylmalate dehydrogenase low > 76
Shewanella loihica PV-4 0.73 Shew_1047 L-aspartate oxidase (RefSeq) 0.70 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) — —
Escherichia coli ECOR27 0.73 NOLOHH_13045 nadB L-aspartate oxidase 0.77 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.43 62
Escherichia coli ECRC62 0.73 BNILDI_11845 nadB L-aspartate oxidase 0.77 BNILDI_08545 leuA 2-isopropylmalate synthase low > 75
Enterobacter sp. TBS_079 0.73 MPMX20_03445 L-aspartate oxidase 0.77 MPMX20_00768 3-isopropylmalate dehydrogenase 0.38 34
Dickeya dianthicola 67-19 0.73 HGI48_RS15855 L-aspartate oxidase 0.78 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.78 37
Escherichia coli BW25113 0.73 b2574 nadB L-aspartate oxidase (NCBI) 0.77 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.58 38
Escherichia coli ECOR38 0.73 HEPCGN_20515 nadB L-aspartate oxidase 0.77 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase low > 88
Escherichia fergusonii Becca 0.73 EFB2_01322 L-aspartate oxidase 0.77 EFB2_03972 3-isopropylmalate dehydrogenase low > 86
Escherichia coli Nissle 1917 0.73 ECOLIN_RS14570 L-aspartate oxidase 0.77 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.58 44
Escherichia coli BL21 0.73 ECD_02468 quinolinate synthase, L-aspartate oxidase (B protein) subunit 0.77 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.38 48
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.73 GFF2106 L-aspartate oxidase (EC 1.4.3.16) 0.77 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 78
Escherichia coli ECRC101 0.73 MCAODC_11900 nadB L-aspartate oxidase 0.77 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.38 82
Dickeya dadantii 3937 0.73 DDA3937_RS15770 L-aspartate oxidase 0.78 DDA3937_RS18120 3-isopropylmalate dehydrogenase low > 74
Escherichia coli ECRC98 0.73 JDDGAC_25035 nadB L-aspartate oxidase 0.77 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase low > 87
Dickeya dianthicola ME23 0.73 DZA65_RS16935 L-aspartate oxidase 0.78 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.71 49
Escherichia coli HS(pFamp)R (ATCC 700891) 0.73 OHPLBJKB_01133 L-aspartate oxidase 0.77 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 74
Escherichia coli ECRC100 0.73 OKFHMN_21370 nadB L-aspartate oxidase 0.77 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase low > 79
Escherichia coli ECRC102 0.73 NIAGMN_19140 nadB L-aspartate oxidase 0.77 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase low > 80
Escherichia coli ECRC99 0.73 KEDOAH_06850 nadB L-aspartate oxidase 0.77 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Klebsiella michiganensis M5al 0.73 BWI76_RS21360 L-aspartate oxidase 0.77 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.35 74
Klebsiella pneumoniae MKP103 0.72 KDGMDA_28485 L-aspartate oxidase 0.77 KDGMDA_12905 3-isopropylmalate dehydrogenase low > 94
Klebsiella pneumoniae MRSN742743 0.72 GJGHJB_01208 nadB L-aspartate oxidase 0.77 GJGHJB_04207 leuB 3-isopropylmalate dehydrogenase low > 83
Pectobacterium carotovorum WPP14 0.72 HER17_RS05775 L-aspartate oxidase 0.78 HER17_RS03080 3-isopropylmalate dehydrogenase 0.88 34
Serratia liquefaciens MT49 0.72 IAI46_19590 L-aspartate oxidase 0.79 IAI46_03350 3-isopropylmalate dehydrogenase low > 87
Rahnella sp. WP5 0.71 EX31_RS21795 L-aspartate oxidase 0.79 EX31_RS03685 3-isopropylmalate dehydrogenase 0.67 44
Pantoea sp. MT58 0.71 IAI47_04845 L-aspartate oxidase 0.73 IAI47_16005 3-isopropylmalate dehydrogenase 0.73 41
Pantoea agglomerans CFBP13505 P0401 0.71 PagCFBP13516_RS05135 nadB L-aspartate oxidase 0.73 PagCFBP13516_RS16315 leuB 3-isopropylmalate dehydrogenase low > 80
Alteromonas macleodii MIT1002 0.71 MIT1002_02720 L-aspartate oxidase 0.62 MIT1002_00948 3-isopropylmalate dehydrogenase — —
Kangiella aquimarina DSM 16071 0.66 B158DRAFT_2179 L-aspartate oxidase (EC 1.4.3.16) 0.51 B158DRAFT_1322 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 40
Pseudomonas aeruginosa MRSN321 0.65 PFGADD_04375 nadB L-aspartate oxidase 0.51 PFGADD_01847 leuB 3-isopropylmalate dehydrogenase low > 99
Pseudomonas aeruginosa PUPa3 0.65 NPBIFN_04431 nadB L-aspartate oxidase 0.51 NPBIFN_01884 leuB 3-isopropylmalate dehydrogenase low > 101
Pseudomonas aeruginosa PA14 0.65 IKLFDK_03260 L-aspartate oxidase 0.51 IKLFDK_15865 3-isopropylmalate dehydrogenase low > 98
Pseudomonas fluorescens FW300-N2E3 0.65 AO353_17620 L-aspartate oxidase 0.51 AO353_20635 3-isopropylmalate dehydrogenase low > 101
Pseudomonas syringae pv. syringae B728a ΔmexB 0.65 Psyr_3959 L-aspartate oxidase 0.49 Psyr_1985 3-isopropylmalate dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a 0.65 Psyr_3959 L-aspartate oxidase 0.49 Psyr_1985 3-isopropylmalate dehydrogenase 0.56 26
Pseudomonas fluorescens GW456-L13 0.65 PfGW456L13_4517 L-aspartate oxidase (EC 1.4.3.16) 0.50 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 87
Pseudomonas sp. RS175 0.65 PFR28_00689 L-aspartate oxidase 0.51 PFR28_02821 3-isopropylmalate dehydrogenase low > 88
Pseudomonas sp. SVBP6 0.64 COO64_RS16520 nadB L-aspartate oxidase 0.52 COO64_RS05650 leuB 3-isopropylmalate dehydrogenase 0.71 41
Pseudomonas fluorescens FW300-N2C3 0.64 AO356_04580 L-aspartate oxidase 0.51 AO356_21415 3-isopropylmalate dehydrogenase low > 104
Pseudomonas fluorescens SBW25-INTG 0.64 PFLU_RS07225 L-aspartate oxidase 0.51 PFLU_RS20565 3-isopropylmalate dehydrogenase low > 109
Pseudomonas fluorescens FW300-N1B4 0.64 Pf1N1B4_3322 L-aspartate oxidase (EC 1.4.3.16) 0.51 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 87
Pseudomonas fluorescens SBW25 0.64 PFLU_RS07225 L-aspartate oxidase 0.51 PFLU_RS20565 3-isopropylmalate dehydrogenase low > 109
Pseudomonas protegens RBAN4 0.64 FABNJH_07550 nadB L-aspartate oxidase 0.51 FABNJH_10785 leuB 3-isopropylmalate dehydrogenase — —
Pseudomonas orientalis W4I3 0.64 QF045_RS09830 L-aspartate oxidase 0.51 QF045_RS20725 3-isopropylmalate dehydrogenase low > 93
Pseudomonas simiae WCS417 0.64 PS417_07115 L-aspartate oxidase 0.51 PS417_18585 3-isopropylmalate dehydrogenase 0.52 7
Pseudomonas sp. BP01 0.64 JOY50_RS14660 nadB L-aspartate oxidase 0.52 JOY50_RS16615 leuB 3-isopropylmalate dehydrogenase 0.93 3
Pseudomonas putida KT2440 0.64 PP_1426 L-aspartate oxidase 0.51 PP_1988 3-isopropylmalate dehydrogenase 0.45 20
Pseudomonas lactucae CFBP13502 0.64 GEMAOFIL_01571 L-aspartate oxidase 0.50 GEMAOFIL_03945 3-isopropylmalate dehydrogenase low > 96
Pseudomonas sp. DMC3 0.64 GFF2276 L-aspartate oxidase 0.50 GFF788 3-isopropylmalate dehydrogenase low > 89
Pseudomonas sp. FW215-L2 0.63 GFF1029 L-aspartate oxidase 0.51 GFF3190 3-isopropylmalate dehydrogenase 0.24 74
Pseudomonas sp. S08-1 0.63 OH686_20040 L-aspartate oxidase 0.50 OH686_04470 3-isopropylmalate dehydrogenase low > 80
Pseudomonas segetis P6 0.63 ACVTMO_RS06935 nadB L-aspartate oxidase 0.51 ACVTMO_RS15215 leuB 3-isopropylmalate dehydrogenase low > 75
Pseudomonas stutzeri RCH2 0.63 Psest_3101 L-aspartate oxidase 0.50 Psest_2589 3-isopropylmalate dehydrogenase 0.19 57
Pseudomonas fluorescens FW300-N2E2 0.63 Pf6N2E2_2758 L-aspartate oxidase (EC 1.4.3.16) 0.51 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.28 36
Marinobacter adhaerens HP15 0.60 HP15_774 L-aspartate oxidase 0.51 HP15_1832 3-isopropylmalate dehydrogenase low > 73
Acinetobacter radioresistens SK82 0.58 MPMX26_02162 L-aspartate oxidase 0.50 MPMX26_00348 3-isopropylmalate dehydrogenase low > 36
Ralstonia solanacearum PSI07 0.58 RPSI07_RS12660 L-aspartate oxidase 0.48 RPSI07_RS14705 3-isopropylmalate dehydrogenase low > 81
Ralstonia sp. UNC404CL21Col 0.58 ABZR87_RS00345 L-aspartate oxidase 0.47 ABZR87_RS14530 3-isopropylmalate dehydrogenase low > 80
Ralstonia solanacearum GMI1000 0.58 RS_RS12285 L-aspartate oxidase 0.48 RS_RS09990 3-isopropylmalate dehydrogenase low > 80
Paraburkholderia graminis OAS925 0.58 ABIE53_003292 L-aspartate oxidase 0.47 ABIE53_004804 3-isopropylmalate dehydrogenase 0.36 16
Paraburkholderia bryophila 376MFSha3.1 0.58 H281DRAFT_04069 L-aspartate oxidase 0.47 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.46 19
Paraburkholderia sabiae LMG 24235 0.58 QEN71_RS03070 L-aspartate oxidase 0.47 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.56 99
Acinetobacter baumannii LAC-4 0.58 RR41_RS04820 L-aspartate oxidase 0.50 RR41_RS16885 3-isopropylmalate dehydrogenase low > 55
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS04725 L-aspartate oxidase 0.48 RALBFv3_RS02610 3-isopropylmalate dehydrogenase low > 76
Ralstonia solanacearum UW163 0.58 UW163_RS08945 L-aspartate oxidase 0.48 UW163_RS11115 3-isopropylmalate dehydrogenase — —
Methylophilus sp. DMC18 0.57 GFF2729 L-aspartate oxidase 0.52 GFF648 3-isopropylmalate dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.57 RR42_RS17010 L-aspartate oxidase 0.47 RR42_RS14385 3-isopropylmalate dehydrogenase low > 128
Burkholderia phytofirmans PsJN 0.57 BPHYT_RS15640 L-aspartate oxidase 0.47 BPHYT_RS33900 3-isopropylmalate dehydrogenase 0.41 17
Collimonas humicola GW821-FHT01A05 0.57 MPMX01_03306 L-aspartate oxidase 0.47 MPMX01_02746 3-isopropylmalate dehydrogenase low > 87
Dechlorosoma suillum PS 0.56 Dsui_2452 L-aspartate oxidase 0.50 Dsui_3198 3-isopropylmalate dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.56 HSERO_RS11085 L-aspartate oxidase 0.47 HSERO_RS16500 3-isopropylmalate dehydrogenase 0.73 7
Variovorax sp. SCN45 0.55 GFF2580 L-aspartate oxidase (EC 1.4.3.16) 0.50 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 127
Magnetospirillum magneticum AMB-1 0.55 AMB_RS19650 L-aspartate oxidase 0.46 AMB_RS20570 3-isopropylmalate dehydrogenase — —
Sphingobium sp. HT1-2 0.55 GFF3783 L-aspartate oxidase (EC 1.4.3.16) 0.44 GFF3458 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 95
Hydrogenophaga sp. GW460-11-11-14-LB1 0.54 GFF1214 L-aspartate oxidase (EC 1.4.3.16) 0.49 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 92
Variovorax sp. OAS795 0.54 ABID97_RS07440 L-aspartate oxidase 0.50 ABID97_RS08455 3-isopropylmalate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.53 Ac3H11_3824 L-aspartate oxidase (EC 1.4.3.16) 0.50 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.65 25
Castellaniella sp019104865 MT123 0.52 ABCV34_RS03690 L-aspartate oxidase 0.48 ABCV34_RS04280 3-isopropylmalate dehydrogenase low > 48
Sphingomonas koreensis DSMZ 15582 0.51 Ga0059261_2248 L-aspartate oxidase (EC 1.4.3.16) 0.49 Ga0059261_3190 3-isopropylmalate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.46 CA265_RS21185 L-aspartate oxidase 0.42 CA265_RS15850 3-isopropylmalate dehydrogenase low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.45 ABZR88_RS20645 L-aspartate oxidase 0.43 ABZR88_RS11605 3-isopropylmalate dehydrogenase — —
Parabacteroides merdae CL09T00C40 0.42 HMPREF1078_RS06605 L-aspartate oxidase 0.40 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase — —
Phocaeicola dorei CL03T12C01 0.42 ABI39_RS05945 L-aspartate oxidase 0.40 ABI39_RS10215 3-isopropylmalate dehydrogenase — —
Phocaeicola vulgatus CL09T03C04 0.42 HMPREF1058_RS11085 L-aspartate oxidase 0.41 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase — —
Bacteroides stercoris CC31F 0.41 HMPREF1181_RS01800 L-aspartate oxidase 0.40 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase — —
Bacteroides ovatus ATCC 8483 0.40 BACOVA_02888 L-aspartate oxidase 0.40 BACOVA_04600 3-isopropylmalate dehydrogenase low > 96
Bacteroides thetaiotaomicron VPI-5482 0.40 BT3184 L-aspartate oxidase (NCBI ptt file) 0.40 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.78 33
Desulfovibrio vulgaris Miyazaki F 0.32 DvMF_0526 L-aspartate oxidase (RefSeq) 0.52 DvMF_1794 3-isopropylmalate dehydrogenase (RefSeq) — —
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU1809 nadB L-aspartate oxidase (TIGR) 0.51 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) — —
Synechocystis sp000284455 PCC 6803 0.30 SGL_RS17230 L-aspartate oxidase 0.47 SGL_RS09375 3-isopropylmalate dehydrogenase — —
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_1881 nadB L-aspartate oxidase 0.46 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase — —
Sinorhizobium meliloti 1021 0.27 SMc02599 L-aspartate oxidase 0.42 SMc04405 3-isopropylmalate dehydrogenase 0.39 27
Azospirillum sp. SherDot2 0.26 MPMX19_05671 L-aspartate oxidase 0.46 MPMX19_00607 3-isopropylmalate dehydrogenase low > 112
Bifidobacterium breve UCC2003 0.25 BBR_RS16725 L-aspartate oxidase 0.28 BBR_RS12870 3-isopropylmalate dehydrogenase low > 34

Not shown: 0 genomes with orthologs for CSW01_12495 only; 28 genomes with orthologs for CSW01_12600 only