Conservation of cofitness between CSW01_17810 and CSW01_04915 in Vibrio cholerae E7946 ATCC 55056

71 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_17810 cobyric acid synthase CobQ 1.0 CSW01_04915 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB 0.64 9
Pseudomonas aeruginosa PA14 0.62 IKLFDK_06055 cobyric acid synthase 0.64 IKLFDK_20540 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 100
Methylophilus sp. DMC18 0.61 GFF1471 Cobyric acid synthase 0.52 GFF2710 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 43
Pseudomonas syringae pv. syringae B728a ΔmexB 0.61 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.64 Psyr_4345 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 86
Pseudomonas syringae pv. syringae B728a 0.61 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.64 Psyr_4345 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 86
Pseudomonas segetis P6 0.61 MPMX49_01822 Cobyric acid synthase 0.62 MPMX49_01071 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 75
Pseudomonas sp. SVBP6 0.60 COO64_RS07225 cobyric acid synthase 0.63 COO64_RS15510 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 93
Pseudomonas stutzeri RCH2 0.60 Psest_3008 cobyric acid synthase CobQ 0.64 Psest_0532 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB low > 67
Shewanella sp. ANA-3 0.60 Shewana3_3275 cobyric acid synthase (RefSeq) 0.78 Shewana3_1008 tRNA-i(6)A37 thiotransferase enzyme MiaB (RefSeq) low > 73
Pseudomonas sp. S08-1 0.60 OH686_04965 cobyric acid synthase CobQ 0.64 OH686_09215 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 80
Pseudomonas fluorescens GW456-L13 0.60 PfGW456L13_4238 Cobyric acid synthase (EC 6.3.5.10) 0.63 PfGW456L13_1380 tRNA-i(6)A37 methylthiotransferase low > 87
Lysobacter sp. OAE881 0.60 ABIE51_RS04965 cobyric acid synthase 0.63 ABIE51_RS15455 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 62
Pseudomonas sp. DMC3 0.60 GFF2552 Cobyric acid synthase 0.63 GFF3900 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 89
Shewanella oneidensis MR-1 0.60 SO1038 cobQ cobyric acid synthase CobQ (NCBI ptt file) 0.78 SO1181 miaB tRNA-i(6)A37 modification enzyme MiaB (NCBI ptt file) low > 76
Pseudomonas fluorescens FW300-N1B4 0.59 Pf1N1B4_3711 Cobyric acid synthase (EC 6.3.5.10) 0.63 Pf1N1B4_2712 tRNA-i(6)A37 methylthiotransferase low > 87
Pseudomonas fluorescens FW300-N2E2 0.59 Pf6N2E2_5742 Cobyric acid synthase (EC 6.3.5.10) 0.63 Pf6N2E2_5018 tRNA-i(6)A37 methylthiotransferase low > 103
Pseudomonas fluorescens FW300-N2E3 0.59 AO353_02615 cobyric acid synthase 0.63 AO353_06375 (dimethylallyl)adenosine tRNA methylthiotransferase low > 101
Pseudomonas simiae WCS417 0.59 PS417_20040 cobyric acid synthase 0.63 PS417_24625 (dimethylallyl)adenosine tRNA methylthiotransferase low > 88
Pseudomonas lactucae CFBP13502 0.59 GEMAOFIL_04205 Cobyric acid synthase 0.63 GEMAOFIL_05078 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 93
Shewanella loihica PV-4 0.59 Shew_0717 cobyric acid synthase (RefSeq) 0.78 Shew_2923 tRNA-i(6)A37 thiotransferase enzyme MiaB (RefSeq) low > 60
Pseudomonas sp. RS175 0.59 PFR28_03204 Cobyric acid synthase 0.63 PFR28_03848 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 88
Pseudomonas fluorescens SBW25-INTG 0.58 PFLU_RS22005 cobyric acid synthase 0.63 PFLU_RS26555 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 109
Pseudomonas fluorescens SBW25 0.58 PFLU_RS22005 cobyric acid synthase 0.63 PFLU_RS26555 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 109
Dyella japonica UNC79MFTsu3.2 0.58 ABZR86_RS10900 cobyric acid synthase 0.64 ABZR86_RS09895 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 74
Pseudomonas fluorescens FW300-N2C3 0.58 AO356_19160 cobyric acid synthase 0.63 AO356_15410 (dimethylallyl)adenosine tRNA methylthiotransferase low > 104
Ralstonia sp. UNC404CL21Col 0.57 ABZR87_RS00040 cobyric acid synthase 0.59 ABZR87_RS07780 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 80
Cupriavidus basilensis FW507-4G11 0.57 RR42_RS16075 cobyric acid synthase 0.59 RR42_RS02855 dimethylallyladenosine tRNA methylthiotransferase low > 128
Rhodanobacter sp. FW510-T8 0.57 OKGIIK_05500 cobyric acid synthase 0.63 OKGIIK_02990 miaB tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 52
Herbaspirillum seropedicae SmR1 0.57 HSERO_RS13230 cobyric acid synthase 0.59 HSERO_RS03615 (dimethylallyl)adenosine tRNA methylthiotransferase low > 78
Ralstonia solanacearum GMI1000 0.57 RS_RS12000 cobyric acid synthase 0.59 RS_RS02645 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 80
Ralstonia solanacearum PSI07 0.57 RPSI07_RS12925 cobyric acid synthase 0.59 RPSI07_RS21380 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 81
Ralstonia solanacearum IBSBF1503 0.56 RALBFv3_RS04445 cobyric acid synthase 0.59 RALBFv3_RS11825 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 76
Ralstonia solanacearum UW163 0.56 UW163_RS09225 cobyric acid synthase 0.59 UW163_RS01760 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB — —
Paraburkholderia sabiae LMG 24235 0.56 QEN71_RS25095 cobyric acid synthase 0.59 QEN71_RS02195 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 153
Paraburkholderia bryophila 376MFSha3.1 0.56 H281DRAFT_00146 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.59 H281DRAFT_04239 tRNA-i(6)A37 thiotransferase enzyme MiaB low > 103
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS04900 cobyric acid synthase 0.58 BPHYT_RS16535 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase low > 109
Shewanella amazonensis SB2B 0.55 Sama_0765 cobyric acid synthase (RefSeq) 0.79 Sama_2575 tRNA-i(6)A37 modification enzyme MiaB (RefSeq) low > 62
Dechlorosoma suillum PS 0.54 Dsui_0542 cobyric acid synthase CobQ 0.61 Dsui_1194 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB low > 51
Azospirillum brasilense Sp245 0.47 AZOBR_RS09845 cobyric acid synthase 0.42 AZOBR_RS01475 (dimethylallyl)adenosine tRNA methylthiotransferase low > 97
Azospirillum sp. SherDot2 0.44 MPMX19_01025 Cobyric acid synthase 0.44 MPMX19_02511 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase — —
Caulobacter crescentus NA1000 Δfur 0.44 CCNA_01827 cobyric acid synthase CobQ 0.42 CCNA_00054 tRNA 2-methylthioadenosine synthase low > 67
Caulobacter crescentus NA1000 0.44 CCNA_01827 cobyric acid synthase CobQ 0.42 CCNA_00054 tRNA 2-methylthioadenosine synthase low > 66
Rhodospirillum rubrum S1H 0.43 Rru_A3381 Cobyric acid synthase CobQ (NCBI) 0.42 Rru_A3770 tRNA-i(6)A37 modification enzyme MiaB (NCBI) low > 58
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.43 GFF3966 Cobyric acid synthase (EC 6.3.5.10) 0.79 GFF4579 tRNA-i(6)A37 methylthiotransferase low > 78
Klebsiella michiganensis M5al 0.43 BWI76_RS23010 cobyric acid synthase CobQ 0.79 BWI76_RS08135 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB — —
Sinorhizobium meliloti 1021 0.42 SMc04309 cobyric acid synthase 0.42 SMc01115 (dimethylallyl)adenosine tRNA methylthiotransferase — —
Rhizobium sp. OAE497 0.41 ABIE40_RS11175 cobyric acid synthase 0.41 ABIE40_RS01705 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 107
Magnetospirillum magneticum AMB-1 0.41 AMB_RS01485 cobyric acid synthase 0.44 AMB_RS22585 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase — —
Rhodopseudomonas palustris CGA009 0.41 TX73_010800 cobyric acid synthase 0.38 TX73_002325 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 86
Klebsiella pneumoniae MKP103 0.41 KDGMDA_03575 cobyric acid synthase 0.79 KDGMDA_16495 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 95
Agrobacterium fabrum C58 0.41 Atu2808 cobyric acid synthase 0.41 Atu0356 miaB protein low > 89
Sphingobium sp. HT1-2 0.40 GFF66 Cobyric acid synthase (EC 6.3.5.10) 0.39 GFF3937 tRNA-i(6)A37 methylthiotransferase (EC 2.8.4.3) low > 95
Phaeobacter inhibens DSM 17395 0.39 PGA1_c24000 cobyric acid synthase CobQ 0.41 PGA1_c04710 (dimethylallyl)adenosine tRNA methylthiotransferase MiaB — —
Parabacteroides merdae CL09T00C40 0.39 HMPREF1078_RS00930 cobyric acid synthase 0.31 HMPREF1078_RS17135 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 61
Synechococcus elongatus PCC 7942 0.39 Synpcc7942_0211 cobQ cobyric acid synthase 0.34 Synpcc7942_2374 tRNA-i(6)A37 thiotransferase enzyme MiaB — —
Sphingomonas koreensis DSMZ 15582 0.38 Ga0059261_0630 adenosylcobyric acid synthase (glutamine-hydrolysing) (EC 6.3.5.10) 0.36 Ga0059261_1604 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB low > 68
Xanthobacter sp. DMC5 0.38 GFF372 Cobyric acid synthase 0.44 GFF3719 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase — —
Fusobacterium nucleatum SB010 0.38 HUW76_05230 cobyric acid synthase 0.33 HUW76_07655 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 35
Phocaeicola dorei CL03T12C01 0.37 ABI39_RS15660 cobyric acid synthase 0.32 ABI39_RS05650 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 72
Phocaeicola vulgatus CL09T03C04 0.37 HMPREF1058_RS01395 cobyric acid synthase 0.32 HMPREF1058_RS11280 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 67
Synechocystis sp000284455 PCC 6803 0.37 SGL_RS15620 cobyric acid synthase CobQ 0.35 SGL_RS04845 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 52
Desulfovibrio vulgaris Hildenborough JW710 0.37 DVU0816 cobQ cobyric acid synthase CobQ (TIGR) 0.30 DVU0984 miaB tRNA-i(6)A37 modification enzyme MiaB (TIGR) low > 55
Bosea sp. OAE506 0.37 ABIE41_RS03845 cobyric acid synthase 0.41 ABIE41_RS04495 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB — —
Dinoroseobacter shibae DFL-12 0.36 Dshi_2096 cobyric acid synthase CobQ (RefSeq) 0.43 Dshi_1019 RNA modification enzyme, MiaB family (RefSeq) — —
Mycobacterium tuberculosis H37Rv 0.35 Rv0255c Probable cobyric acid synthase CobQ1 0.34 Rv2733c Conserved hypothetical alanine, arginine-rich protein low > 58
Methanococcus maripaludis JJ 0.35 MMJJ_RS08095 cobyric acid synthase CobQ 0.16 MMJJ_RS03110 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase low > 28
Methanococcus maripaludis S2 0.35 MMP_RS06255 cobyric acid synthase CobQ 0.16 MMP_RS02195 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase — —
Desulfovibrio vulgaris Miyazaki F 0.35 DvMF_2864 cobyric acid synthase (RefSeq) 0.31 DvMF_1330 RNA modification enzyme, MiaB family (RefSeq) — —
Variovorax sp. SCN45 0.32 GFF426 Cobyric acid synthase (EC 6.3.5.10) 0.60 GFF7320 tRNA-i(6)A37 methylthiotransferase (EC 2.8.4.3) low > 127
Variovorax sp. OAS795 0.31 ABID97_RS17340 cobyric acid synthase 0.59 ABID97_RS06475 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF3998 Cobyric acid synthase (EC 6.3.5.10) 0.59 GFF613 tRNA-i(6)A37 methylthiotransferase low > 90
Acidovorax sp. GW101-3H11 0.30 Ac3H11_999 Cobyric acid synthase (EC 6.3.5.10) 0.59 Ac3H11_4008 tRNA-i(6)A37 methylthiotransferase low > 79

Not shown: 3 genomes with orthologs for CSW01_17810 only; 46 genomes with orthologs for CSW01_04915 only