Conservation of cofitness between BWI76_RS25485 and BWI76_RS03040 in Klebsiella michiganensis M5al

81 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS25485 septum formation protein Maf 1.0 BWI76_RS03040 leucyl aminopeptidase 0.27 8
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.89 GFF2137 Septum formation protein Maf 0.96 GFF949 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 78
Escherichia coli ECOR27 0.86 NOLOHH_09525 yhdE nucleoside triphosphate pyrophosphatase YhdE 0.95 NOLOHH_04055 pepA leucyl aminopeptidase low > 75
Escherichia coli ECRC62 0.86 BNILDI_01995 yhdE nucleoside triphosphate pyrophosphatase YhdE 0.95 BNILDI_07455 pepA leucyl aminopeptidase low > 75
Escherichia coli Nissle 1917 0.85 ECOLIN_RS18610 nucleoside triphosphate pyrophosphatase YhdE 0.95 ECOLIN_RS24695 leucyl aminopeptidase low > 55
Escherichia coli ECOR38 0.85 HEPCGN_16605 yhdE nucleoside triphosphate pyrophosphatase YhdE 0.95 HEPCGN_09980 pepA leucyl aminopeptidase low > 87
Escherichia fergusonii Becca 0.85 EFB2_00583 dTTP/UTP pyrophosphatase 0.95 EFB2_04275 Cytosol aminopeptidase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.84 OHPLBJKB_00457 Maf-like protein YhdE 0.95 OHPLBJKB_03776 Cytosol aminopeptidase low > 73
Escherichia coli BL21 0.84 ECD_03107 dTTP/UTP pyrophosphatase; m(5)UTP/m(5)CTP/pseudo-UTP pyrophosphatase 0.95 ECD_04126 multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site-specific recombination factor low > 61
Escherichia coli BW25113 0.84 b3248 yhdE Maf-like protein (NCBI) 0.95 b4260 pepA leucyl aminopeptidase (NCBI) low > 76
Escherichia coli ECRC98 0.84 JDDGAC_21365 yhdE nucleoside triphosphate pyrophosphatase YhdE 0.95 JDDGAC_15430 pepA leucyl aminopeptidase low > 86
Escherichia coli ECRC102 0.84 NIAGMN_15500 yhdE nucleoside triphosphate pyrophosphatase YhdE 0.95 NIAGMN_09640 pepA leucyl aminopeptidase — —
Escherichia coli ECRC100 0.84 OKFHMN_17740 yhdE nucleoside triphosphate pyrophosphatase YhdE 0.95 OKFHMN_11790 pepA leucyl aminopeptidase low > 80
Escherichia coli ECRC99 0.84 KEDOAH_10410 yhdE nucleoside triphosphate pyrophosphatase YhdE 0.95 KEDOAH_16360 pepA leucyl aminopeptidase — —
Enterobacter asburiae PDN3 0.84 EX28DRAFT_3298 MAF protein 0.96 EX28DRAFT_3267 Leucyl aminopeptidase low > 76
Escherichia coli ECRC101 0.83 MCAODC_08260 yhdE nucleoside triphosphate pyrophosphatase YhdE 0.95 MCAODC_02295 pepA leucyl aminopeptidase low > 87
Enterobacter sp. TBS_079 0.82 MPMX20_04154 dTTP/UTP pyrophosphatase 0.96 MPMX20_04118 Cytosol aminopeptidase low > 85
Pantoea sp. MT58 0.76 IAI47_02450 septum formation inhibitor Maf 0.93 IAI47_16795 leucyl aminopeptidase low > 76
Serratia liquefaciens MT49 0.69 IAI46_22705 septum formation inhibitor Maf 0.93 IAI46_02360 leucyl aminopeptidase low > 86
Erwinia tracheiphila SCR3 0.69 LU632_RS21435 Maf-like protein 0.94 LU632_RS20855 pepA leucyl aminopeptidase low > 74
Pectobacterium carotovorum WPP14 0.69 HER17_RS20155 Maf-like protein 0.90 HER17_RS19450 leucyl aminopeptidase low > 75
Rahnella sp. WP5 0.65 EX31_RS12250 septum formation inhibitor Maf 0.93 EX31_RS04385 leucyl aminopeptidase low > 89
Dickeya dadantii 3937 0.61 DDA3937_RS01445 septum formation inhibitor Maf 0.91 DDA3937_RS01995 leucyl aminopeptidase low > 74
Dickeya dianthicola ME23 0.58 DZA65_RS01425 septum formation inhibitor Maf 0.91 DZA65_RS02060 leucyl aminopeptidase low > 75
Dickeya dianthicola 67-19 0.57 HGI48_RS01365 septum formation inhibitor Maf 0.91 HGI48_RS01955 leucyl aminopeptidase low > 71
Shewanella loihica PV-4 0.52 Shew_0406 maf protein (RefSeq) 0.79 Shew_0939 leucyl aminopeptidase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.49 Sama_0470 maf protein (RefSeq) 0.79 Sama_0795 leucyl aminopeptidase (RefSeq) low > 62
Shewanella oneidensis MR-1 0.49 SO4095 maf maf protein (NCBI ptt file) 0.78 SO1368 pepA-2 cytosol aminopeptidase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.49 Shewana3_3645 maf protein (RefSeq) 0.78 Shewana3_3006 leucyl aminopeptidase (RefSeq) low > 73
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_02200 septum formation inhibitor Maf 0.82 CSW01_12680 cytosol aminopeptidase 0.77 11
Marinobacter adhaerens HP15 0.49 HP15_2452 Maf-like protein 0.46 HP15_1315 leucyl aminopeptidase — —
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_5030 Septum formation protein Maf 0.53 PfGW456L13_4846 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 87
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_05235 septum formation protein Maf 0.53 AO353_04535 aminopeptidase low > 101
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_1096 Septum formation protein Maf 0.53 Pf1N1B4_898 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 87
Pseudomonas sp. RS175 0.47 PFR28_00157 dTTP/UTP pyrophosphatase 0.53 PFR28_03528 Cytosol aminopeptidase low > 88
Pseudomonas putida KT2440 0.47 PP_0936 septum formation protein 0.51 PP_0980 Probable cytosol aminopeptidase low > 96
Pseudomonas simiae WCS417 0.46 PS417_04265 septum formation protein Maf 0.52 PS417_05165 cytosol aminopeptidase low > 88
Pseudomonas stutzeri RCH2 0.46 Psest_3324 MAF protein 0.50 Psest_1235 Leucyl aminopeptidase low > 67
Pseudomonas fluorescens SBW25 0.44 PFLU_RS04320 septum formation inhibitor Maf 0.53 PFLU_RS05235 leucyl aminopeptidase low > 109
Pseudomonas fluorescens FW300-N2E2 0.44 Pf6N2E2_3284 Septum formation protein Maf 0.53 Pf6N2E2_5420 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 103
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_4160 Maf-like protein 0.53 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 low > 86
Pseudomonas fluorescens SBW25-INTG 0.44 PFLU_RS04320 septum formation inhibitor Maf 0.53 PFLU_RS05235 leucyl aminopeptidase low > 109
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_4160 Maf-like protein 0.53 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 low > 86
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_2068 MAF protein 0.60 B158DRAFT_1167 Leucyl aminopeptidase low > 40
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_07115 septum formation protein Maf 0.53 AO356_17470 aminopeptidase low > 104
Xanthomonas campestris pv. campestris strain 8004 0.41 Xcc-8004.1879.1 Septum formation protein Maf 0.43 Xcc-8004.4446.1 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 74
Pseudomonas sp. S08-1 0.41 OH686_08600 septum formation protein Maf 0.52 OH686_07810 Cytosol aminopeptidase PepA low > 80
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS09045 Maf family protein 0.41 ABZR86_RS19105 leucyl aminopeptidase low > 74
Ralstonia sp. UNC404CL21Col 0.40 ABZR87_RS15435 Maf family protein 0.49 ABZR87_RS00150 leucyl aminopeptidase low > 80
Cupriavidus basilensis FW507-4G11 0.39 RR42_RS04705 septum formation inhibitor Maf 0.46 RR42_RS16225 cytosol aminopeptidase low > 128
Alteromonas macleodii MIT1002 0.39 MIT1002_00223 Maf-like protein YhdE 0.78 MIT1002_03197 Cytosol aminopeptidase low > 70
Dechlorosoma suillum PS 0.37 Dsui_0450 MAF protein 0.59 Dsui_3536 leucyl aminopeptidase low > 51
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS02685 Maf family nucleotide pyrophosphatase 0.43 LRK54_RS12375 leucyl aminopeptidase low > 59
Rhodanobacter denitrificans MT42 0.37 LRK55_RS02440 Maf family protein 0.43 LRK55_RS12110 leucyl aminopeptidase low > 63
Ralstonia solanacearum PSI07 0.37 RPSI07_RS13655 septum formation inhibitor Maf 0.49 RPSI07_RS12825 leucyl aminopeptidase low > 81
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS24425 Maf family protein 0.50 QEN71_RS25205 leucyl aminopeptidase low > 153
Burkholderia phytofirmans PsJN 0.36 BPHYT_RS06380 septum formation protein Maf 0.50 BPHYT_RS04795 cytosol aminopeptidase low > 109
Ralstonia solanacearum UW163 0.36 UW163_RS10100 septum formation inhibitor Maf 0.47 UW163_RS09120 leucyl aminopeptidase — —
Ralstonia solanacearum IBSBF1503 0.36 RALBFv3_RS03570 septum formation inhibitor Maf 0.47 RALBFv3_RS04550 leucyl aminopeptidase low > 76
Castellaniella sp019104865 MT123 0.36 ABCV34_RS02520 Maf family protein 0.43 ABCV34_RS08295 leucyl aminopeptidase — —
Acidovorax sp. GW101-3H11 0.35 Ac3H11_2417 Septum formation protein Maf 0.36 Ac3H11_2399 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 79
Ralstonia solanacearum GMI1000 0.35 RS_RS11020 septum formation inhibitor Maf 0.46 RS_RS12120 cytosol aminopeptidase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_04516 septum formation protein 0.50 H281DRAFT_00123 aminopeptidase A. Metallo peptidase. MEROPS family M17 low > 103
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS17785 septum formation inhibitor Maf 0.47 HSERO_RS15600 cytosol aminopeptidase low > 78
Lysobacter sp. OAE881 0.35 ABIE51_RS06780 Maf family nucleotide pyrophosphatase 0.46 ABIE51_RS04475 leucyl aminopeptidase low > 62
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF4530 Septum formation protein Maf 0.35 GFF4309 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 90
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_02427 septum formation protein Maf 0.31 CCNA_01763 multifunctional aminopeptidase low > 67
Caulobacter crescentus NA1000 0.33 CCNA_02427 septum formation protein Maf 0.31 CCNA_01763 multifunctional aminopeptidase low > 66
Dinoroseobacter shibae DFL-12 0.33 Dshi_0983 maf protein (RefSeq) 0.27 Dshi_1191 Leucyl aminopeptidase (RefSeq) low > 64
Sinorhizobium meliloti 1021 0.33 SMc02311 Maf-like protein 0.29 SMc00585 leucyl aminopeptidase — —
Fusobacterium nucleatum SB010 0.31 HUW76_04640 septum formation protein Maf 0.25 HUW76_01625 leucyl aminopeptidase 0.88 5
Rhodopseudomonas palustris CGA009 0.31 TX73_023520 Maf-like protein 0.26 TX73_015830 leucyl aminopeptidase — —
Variovorax sp. SCN45 0.31 GFF296 Septum formation protein Maf 0.35 GFF240 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 127
Brevundimonas sp. GW460-12-10-14-LB2 0.31 A4249_RS07295 Maf family protein 0.30 A4249_RS06730 leucyl aminopeptidase — —
Variovorax sp. OAS795 0.31 ABID97_RS16710 Maf family nucleotide pyrophosphatase 0.36 ABID97_RS16580 leucyl aminopeptidase low > 91
Rhodospirillum rubrum S1H 0.30 Rru_A2768 Maf-like protein (NCBI) 0.32 Rru_A0454 Leucyl aminopeptidase (NCBI) — —
Azospirillum brasilense Sp245 0.29 AZOBR_RS19535 septum formation protein Maf 0.30 AZOBR_RS16385 aminopeptidase A — —
Azospirillum sp. SherDot2 0.28 MPMX19_05536 dTTP/UTP pyrophosphatase 0.28 MPMX19_01593 Cytosol aminopeptidase — —
Desulfovibrio vulgaris Hildenborough JW710 0.28 DVU0527 maF septum formation protein Maf (TIGR) 0.29 DVU0415 pepA cytosol aminopeptidase (TIGR) low > 55
Magnetospirillum magneticum AMB-1 0.27 AMB_RS16885 septum formation inhibitor Maf 0.34 AMB_RS18600 leucyl aminopeptidase — —
Desulfovibrio vulgaris Miyazaki F 0.26 DvMF_2587 maf protein (RefSeq) 0.28 DvMF_1538 Leucyl aminopeptidase (RefSeq) low > 51
Mycobacterium tuberculosis H37Rv 0.16 Rv3282 Conserved hypothetical protein 0.23 Rv2213 Probable aminopeptidase PepB low > 58

Not shown: 17 genomes with orthologs for BWI76_RS25485 only; 2 genomes with orthologs for BWI76_RS03040 only