Conservation of cofitness between BBR_RS15810 and BBR_RS16510 in Bifidobacterium breve UCC2003

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bifidobacterium breve UCC2003 1.0 BBR_RS15810 tryptophan synthase subunit alpha 1.0 BBR_RS16510 anthranilate phosphoribosyltransferase 0.88 1
Mycobacterium tuberculosis H37Rv 0.40 Rv1613 Probable tryptophan synthase, alpha subunit TrpA 0.33 Rv2192c Probable anthranilate phosphoribosyltransferase TrpD
Rhizobium sp. OAE497 0.27 ABIE40_RS19340 tryptophan synthase subunit alpha 0.30 ABIE40_RS09545 anthranilate phosphoribosyltransferase
Methanococcus maripaludis S2 0.27 MMP_RS05185 tryptophan synthase subunit alpha 0.23 MMP_RS05210 anthranilate phosphoribosyltransferase
Methanococcus maripaludis JJ 0.26 MMJJ_RS09195 tryptophan synthase subunit alpha 0.24 MMJJ_RS09170 anthranilate phosphoribosyltransferase
Synechococcus elongatus PCC 7942 0.26 Synpcc7942_0411 trpA tryptophan synthase subunit alpha 0.23 Synpcc7942_2123 trpD anthranilate phosphoribosyltransferase
Pseudomonas sp. S08-1 0.26 OH686_12430 tryptophan synthase, alpha subunit 0.22 OH686_15135 Anthranilate phosphoribosyltransferase 0.78 29
Marinobacter adhaerens HP15 0.26 HP15_1826 tryptophan synthase, alpha subunit 0.23 HP15_3290 anthranilate phosphoribosyltransferase
Phaeobacter inhibens DSM 17395 0.26 PGA1_c04930 tryptophan synthase alpha chain 0.22 PGA1_c16890 anthranilate phosphoribosyltransferase TrpD
Agrobacterium fabrum C58 0.26 Atu0019 tryptophan synthase alpha subunit 0.30 Atu1687 anthranilate phosphoribosyltransferase
Rhodopseudomonas palustris CGA009 0.26 TX73_000365 tryptophan synthase subunit alpha 0.32 TX73_014980 anthranilate phosphoribosyltransferase
Magnetospirillum magneticum AMB-1 0.26 AMB_RS20300 tryptophan synthase subunit alpha 0.24 AMB_RS14410 anthranilate phosphoribosyltransferase
Pseudomonas simiae WCS417 0.25 PS417_00180 tryptophan synthase subunit alpha 0.19 PS417_25715 anthranilate phosphoribosyltransferase 0.76 3
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_10705 tryptophan synthase subunit alpha 0.19 AO353_07215 anthranilate phosphoribosyltransferase 0.85 4
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.19 PFLU_RS27370 anthranilate phosphoribosyltransferase 0.86 3
Pseudomonas fluorescens SBW25 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.19 PFLU_RS27370 anthranilate phosphoribosyltransferase low > 109
Dinoroseobacter shibae DFL-12 0.25 Dshi_0952 tryptophan synthase, alpha subunit (RefSeq) 0.22 Dshi_1799 anthranilate phosphoribosyltransferase (RefSeq)
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_565 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.20 PfGW456L13_1221 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.96 5
Pseudomonas sp. RS175 0.25 PFR28_04716 Tryptophan synthase alpha chain 0.19 PFR28_04044 Anthranilate phosphoribosyltransferase
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_10910 tryptophan synthase subunit alpha 0.20 AO356_14435 anthranilate phosphoribosyltransferase 0.96 4
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_1830 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.21 Pf1N1B4_2548 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.91 5
Sinorhizobium meliloti 1021 0.25 SMc02765 tryptophan synthase subunit alpha 0.27 SMc00235 anthranilate phosphoribosyltransferase 0.96 4
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4047 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.20 Pf6N2E2_4825 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.94 3
Mucilaginibacter yixingensis YX-36 DSM 26809 0.25 ABZR88_RS10660 tryptophan synthase subunit alpha 0.22 ABZR88_RS10675 anthranilate phosphoribosyltransferase
Acinetobacter radioresistens SK82 0.25 MPMX26_02611 Tryptophan synthase alpha chain 0.24 MPMX26_00984 Anthranilate phosphoribosyltransferase
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.23 Psyr_4580 anthranilate phosphoribosyltransferase 0.55 36
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.23 Psyr_4580 anthranilate phosphoribosyltransferase 0.64 25
Pseudomonas putida KT2440 0.24 PP_0082 tryptophan synthase alpha chain 0.23 PP_0421 Anthranilate phosphoribosyltransferase 0.87 4
Kangiella aquimarina DSM 16071 0.24 B158DRAFT_2430 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.24 B158DRAFT_2427 anthranilate phosphoribosyltransferase low > 40
Acidovorax sp. GW101-3H11 0.24 Ac3H11_1535 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.24 Ac3H11_771 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.98 6
Parabacteroides merdae CL09T00C40 0.23 HMPREF1078_RS00120 tryptophan synthase subunit alpha 0.21 HMPREF1078_RS00135 anthranilate phosphoribosyltransferase 0.98 14
Variovorax sp. SCN45 0.23 GFF3882 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.25 GFF5891 Anthranilate phosphoribosyltransferase (EC 2.4.2.18)
Dechlorosoma suillum PS 0.23 Dsui_3191 tryptophan synthase, alpha subunit 0.23 Dsui_0169 anthranilate phosphoribosyltransferase
Phocaeicola vulgatus CL09T03C04 0.23 HMPREF1058_RS07200 tryptophan synthase subunit alpha 0.24 HMPREF1058_RS07185 anthranilate phosphoribosyltransferase 0.97 2
Phocaeicola dorei CL03T12C01 0.23 ABI39_RS21075 tryptophan synthase subunit alpha 0.24 ABI39_RS21060 anthranilate phosphoribosyltransferase 0.82 3
Bosea sp. OAE506 0.23 ABIE41_RS03930 tryptophan synthase subunit alpha 0.25 ABIE41_RS17420 anthranilate phosphoribosyltransferase
Shewanella oneidensis MR-1 0.23 SO3024 trpA tryptophan synthase, alpha subunit (NCBI ptt file) 0.22 SO3021 trpD anthranilate phosphoribosyltransferase (NCBI ptt file) 0.99 4
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS15350 tryptophan synthase subunit alpha 0.23 HMPREF1181_RS15335 anthranilate phosphoribosyltransferase 0.96 3
Serratia liquefaciens MT49 0.22 IAI46_14045 tryptophan synthase subunit alpha 0.20 IAI46_14030 anthranilate phosphoribosyltransferase low > 86
Bacteroides thetaiotaomicron VPI-5482 0.22 BT0527 tryptophan synthase alpha chain (NCBI ptt file) 0.20 BT0530 anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) 0.76 29
Shewanella sp. ANA-3 0.22 Shewana3_1515 trpA tryptophan synthase subunit alpha (RefSeq) 0.21 Shewana3_1518 trpD anthranilate phosphoribosyltransferase (RefSeq) 0.96 7
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS14350 tryptophan synthase alpha chain 0.26 RR42_RS18305 anthranilate phosphoribosyltransferase
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS14490 tryptophan synthase subunit alpha 0.23 ABZR87_RS02155 anthranilate phosphoribosyltransferase 0.87 14
Variovorax sp. OAS795 0.22 ABID97_RS08425 tryptophan synthase subunit alpha 0.25 ABID97_RS05275 anthranilate phosphoribosyltransferase 0.70 11
Bacteroides ovatus ATCC 8483 0.22 BACOVA_03785 tryptophan synthase, alpha subunit 0.19 BACOVA_03782 anthranilate phosphoribosyltransferase 0.97 4
Azospirillum brasilense Sp245 0.22 AZOBR_RS00520 tryptophan synthase subunit alpha 0.27 AZOBR_RS07455 anthranilate phosphoribosyltransferase 0.70 34
Vibrio cholerae E7946 ATCC 55056 0.22 CSW01_05925 tryptophan synthase subunit alpha 0.23 CSW01_05940 anthranilate phosphoribosyltransferase 0.86 2
Caulobacter crescentus NA1000 0.22 CCNA_03657 tryptophan synthase alpha chain 0.27 CCNA_01975 anthranilate phosphoribosyltransferase 0.97 1
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_03657 tryptophan synthase alpha chain 0.27 CCNA_01975 anthranilate phosphoribosyltransferase low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS11320 tryptophan synthase subunit alpha 0.26 A4249_RS06170 anthranilate phosphoribosyltransferase
Azospirillum sp. SherDot2 0.21 MPMX19_02737 Tryptophan synthase alpha chain 0.27 MPMX19_01015 Anthranilate phosphoribosyltransferase 0.64 35
Ralstonia solanacearum PSI07 0.21 RPSI07_RS14740 tryptophan synthase subunit alpha 0.27 RPSI07_RS02570 anthranilate phosphoribosyltransferase
Ralstonia solanacearum GMI1000 0.21 RS_RS09955 tryptophan synthase subunit alpha 0.27 RS_RS20385 Anthranilate phosphoribosyltransferase 2 low > 80
Pantoea sp. MT58 0.21 IAI47_09165 tryptophan synthase subunit alpha 0.19 IAI47_09180 anthranilate phosphoribosyltransferase 0.98 3
Ralstonia solanacearum UW163 0.21 UW163_RS11150 tryptophan synthase subunit alpha 0.26 UW163_RS18880 anthranilate phosphoribosyltransferase
Ralstonia solanacearum IBSBF1503 0.21 RALBFv3_RS02575 tryptophan synthase subunit alpha 0.26 RALBFv3_RS20295 anthranilate phosphoribosyltransferase
Herbaspirillum seropedicae SmR1 0.21 HSERO_RS16470 tryptophan synthase subunit alpha 0.20 HSERO_RS19445 anthranilate phosphoribosyltransferase 0.73 3
Paraburkholderia graminis OAS925 0.21 ABIE53_004811 tryptophan synthase alpha chain 0.24 ABIE53_003642 anthranilate phosphoribosyltransferase
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_1740 trpA tryptophan synthase subunit alpha (RefSeq) 0.24 DvMF_1744 anthranilate phosphoribosyltransferase (RefSeq) 0.91 3
Dickeya dianthicola ME23 0.20 DZA65_RS10940 tryptophan synthase subunit alpha 0.24 DZA65_RS10955 anthranilate phosphoribosyltransferase 0.92 4
Dickeya dianthicola 67-19 0.20 HGI48_RS10460 tryptophan synthase subunit alpha 0.24 HGI48_RS10475 anthranilate phosphoribosyltransferase 0.80 4
Dickeya dadantii 3937 0.20 DDA3937_RS10460 tryptophan synthase subunit alpha 0.24 DDA3937_RS10475 anthranilate phosphoribosyltransferase 0.87 4
Rahnella sp. WP5 0.20 EX31_RS09980 tryptophan synthase subunit alpha 0.23 EX31_RS09965 anthranilate phosphoribosyltransferase 0.97 12
Xanthomonas campestris pv. campestris strain 8004 0.20 Xcc-8004.1967.1 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.21 Xcc-8004.621.1 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) 0.95 2
Shewanella loihica PV-4 0.20 Shew_2256 trpA tryptophan synthase subunit alpha (RefSeq) 0.22 Shew_2253 anthranilate phosphoribosyltransferase (RefSeq) 0.99 3
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_06065 tryptophan synthase, alpha chain 0.24 H281DRAFT_05713 anthranilate phosphoribosyltransferase 0.57 5
Castellaniella sp019104865 MT123 0.19 ABCV34_RS08430 tryptophan synthase subunit alpha 0.17 ABCV34_RS10305 anthranilate phosphoribosyltransferase
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS33865 tryptophan synthase alpha chain 0.24 BPHYT_RS17400 anthranilate phosphoribosyltransferase 0.91 6
Paraburkholderia sabiae LMG 24235 0.18 QEN71_RS17655 tryptophan synthase subunit alpha 0.24 QEN71_RS27560 anthranilate phosphoribosyltransferase 0.97 3
Shewanella amazonensis SB2B 0.18 Sama_2134 trpA tryptophan synthase subunit alpha (RefSeq) 0.22 Sama_2131 trpD anthranilate phosphoribosyltransferase (RefSeq) 0.99 3
Sphingomonas koreensis DSMZ 15582 0.18 Ga0059261_0239 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.23 Ga0059261_0929 anthranilate phosphoribosyltransferase 0.90 6

Not shown: 21 genomes with orthologs for BBR_RS15810 only; 10 genomes with orthologs for BBR_RS16510 only