Conservation of cofitness between b2903 and b2951 in Escherichia coli BW25113

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2903 gcvP glycine dehydrogenase (NCBI) 1.0 b2951 yggS predicted enzyme (NCBI) 0.47 7
Escherichia coli BL21 1.00 ECD_02735 glycine decarboxylase, PLP-dependent, subunit P of glycine cleavage complex 1.00 ECD_02781 UPF0001 family protein, PLP-binding low > 60
Escherichia coli ECRC62 1.00 BNILDI_09980 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 BNILDI_09705 yggS pyridoxal phosphate homeostasis protein
Escherichia coli ECRC101 1.00 OKFHMN_19530 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 OKFHMN_19255 yggS pyridoxal phosphate homeostasis protein
Escherichia coli ECRC98 1.00 JDDGAC_23170 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 JDDGAC_22885 yggS pyridoxal phosphate homeostasis protein
Escherichia coli ECRC101 1.00 MCAODC_10050 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 MCAODC_09775 yggS pyridoxal phosphate homeostasis protein
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00812 Glycine dehydrogenase (decarboxylating) 1.00 OHPLBJKB_00765 Pyridoxal phosphate homeostasis protein low > 73
Escherichia coli ECRC99 1.00 KEDOAH_08610 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 KEDOAH_08885 yggS pyridoxal phosphate homeostasis protein
Escherichia coli ECRC102 1.00 NIAGMN_17295 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 NIAGMN_17020 yggS pyridoxal phosphate homeostasis protein
Escherichia coli Nissle 1917 1.00 ECOLIN_RS16165 aminomethyl-transferring glycine dehydrogenase 1.00 ECOLIN_RS16415 pyridoxal phosphate homeostasis protein low > 52
Escherichia coli ECOR38 1.00 HEPCGN_18820 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 HEPCGN_18560 yggS pyridoxal phosphate homeostasis protein low > 85
Escherichia fergusonii Becca 0.99 EFB2_00999 Glycine dehydrogenase (decarboxylating) 1.00 EFB2_00951 Pyridoxal phosphate homeostasis protein low > 86
Escherichia coli ECOR27 0.99 NOLOHH_11445 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 NOLOHH_11125 yggS pyridoxal phosphate homeostasis protein low > 57
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF3003 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.89 GFF3054 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 78
Enterobacter sp. TBS_079 0.89 MPMX20_03762 Glycine dehydrogenase (decarboxylating) 0.82 MPMX20_03809 Pyridoxal phosphate homeostasis protein 0.34 5
Klebsiella michiganensis M5al 0.89 BWI76_RS23870 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) 0.87 BWI76_RS24100 YggS family pyridoxal phosphate enzyme low > 92
Enterobacter asburiae PDN3 0.88 EX28DRAFT_2955 glycine dehydrogenase (decarboxylating) 0.87 EX28DRAFT_2989 pyridoxal phosphate enzyme, YggS family low > 76
Pantoea sp. MT58 0.82 IAI47_03775 aminomethyl-transferring glycine dehydrogenase 0.69 IAI47_03595 YggS family pyridoxal phosphate-dependent enzyme low > 76
Serratia liquefaciens MT49 0.82 IAI46_20850 aminomethyl-transferring glycine dehydrogenase 0.67 IAI46_21410 YggS family pyridoxal phosphate-dependent enzyme low > 86
Erwinia tracheiphila SCR3 0.81 LU632_RS05915 gcvP aminomethyl-transferring glycine dehydrogenase 0.68 LU632_RS05460 YggS family pyridoxal phosphate-dependent enzyme low > 74
Rahnella sp. WP5 0.81 EX31_RS21520 aminomethyl-transferring glycine dehydrogenase 0.67 EX31_RS02685 YggS family pyridoxal phosphate-dependent enzyme low > 89
Pectobacterium carotovorum WPP14 0.80 HER17_RS17995 aminomethyl-transferring glycine dehydrogenase 0.69 HER17_RS03810 YggS family pyridoxal phosphate-dependent enzyme 0.49 25
Dickeya dadantii 3937 0.80 DDA3937_RS03255 aminomethyl-transferring glycine dehydrogenase 0.72 DDA3937_RS17300 YggS family pyridoxal phosphate-dependent enzyme low > 74
Dickeya dianthicola ME23 0.80 DZA65_RS03445 aminomethyl-transferring glycine dehydrogenase 0.73 DZA65_RS18435 YggS family pyridoxal phosphate-dependent enzyme low > 75
Dickeya dianthicola 67-19 0.80 HGI48_RS03400 aminomethyl-transferring glycine dehydrogenase 0.72 HGI48_RS17345 YggS family pyridoxal phosphate-dependent enzyme low > 71
Shewanella amazonensis SB2B 0.68 Sama_2719 glycine dehydrogenase (RefSeq) 0.51 Sama_2477 hypothetical protein (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.68 MIT1002_02971 Glycine dehydrogenase [decarboxylating] 0.50 MIT1002_03061 pyridoxal phosphate enzyme, YggS family low > 70
Shewanella oneidensis MR-1 0.67 SO0781 gcvP glycine cleavage system P protein (NCBI ptt file) 0.57 SO3352 conserved hypothetical protein TIGR00044 (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.67 Shewana3_3499 glycine dehydrogenase (RefSeq) 0.54 Shewana3_1194 hypothetical protein (RefSeq) low > 73
Shewanella loihica PV-4 0.66 Shew_3062 glycine dehydrogenase (RefSeq) 0.54 Shew_1137 alanine racemase domain-containing protein (RefSeq) low > 60
Pseudomonas sp. S08-1 0.63 OH686_11165 glycine dehydrogenase 0.51 OH686_10975 Pyridoxal phosphate-containing protein YggS low > 80
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_2236 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.51 Pf1N1B4_2342 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_08720 glycine dehydrogenase 0.48 AO353_08160 hypothetical protein low > 101
Pseudomonas stutzeri RCH2 0.62 Psest_0183 glycine dehydrogenase (decarboxylating) 0.49 Psest_0284 pyridoxal phosphate enzyme, YggS family low > 67
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_904 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.50 PfGW456L13_1011 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 87
Pseudomonas putida KT2440 0.61 PP_5192 glycine dehydrogenase 0.48 PP_5094 putative enzyme with PLP binding domain low > 96
Dechlorosoma suillum PS 0.61 Dsui_2737 glycine dehydrogenase, decarboxylating 0.56 Dsui_0603 pyridoxal phosphate enzyme, YggS family low > 51
Kangiella aquimarina DSM 16071 0.58 B158DRAFT_0545 glycine dehydrogenase (decarboxylating) 0.44 B158DRAFT_0196 pyridoxal phosphate enzyme, YggS family
Vibrio cholerae E7946 ATCC 55056 0.58 CSW01_15330 glycine dehydrogenase (decarboxylating) 0.58 CSW01_02455 YggS family pyridoxal phosphate enzyme low > 62
Pseudomonas syringae pv. syringae B728a ΔmexB 0.56 Psyr_1096 glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit 0.48 Psyr_0477 Protein of unknown function UPF0001 low > 86
Pseudomonas syringae pv. syringae B728a 0.56 Psyr_1096 glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit 0.48 Psyr_0477 Protein of unknown function UPF0001 low > 86
Rhodanobacter denitrificans MT42 0.56 LRK55_RS00260 aminomethyl-transferring glycine dehydrogenase 0.27 LRK55_RS08955 YggS family pyridoxal phosphate-dependent enzyme low > 63
Pseudomonas sp. RS175 0.56 PFR28_03383 Glycine dehydrogenase (decarboxylating) 0.48 PFR28_04242 Pyridoxal phosphate homeostasis protein low > 88
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_5558 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) 0.49 Pf6N2E2_4601 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 103
Dyella japonica UNC79MFTsu3.2 0.56 ABZR86_RS08305 aminomethyl-transferring glycine dehydrogenase 0.28 ABZR86_RS09305 YggS family pyridoxal phosphate-dependent enzyme
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_18170 glycine dehydrogenase 0.51 AO356_13425 hypothetical protein low > 104
Pseudomonas fluorescens SBW25-INTG 0.56 PFLU_RS24000 aminomethyl-transferring glycine dehydrogenase 0.50 PFLU_RS28370 YggS family pyridoxal phosphate-dependent enzyme low > 109
Pseudomonas fluorescens SBW25 0.56 PFLU_RS24000 aminomethyl-transferring glycine dehydrogenase 0.50 PFLU_RS28370 YggS family pyridoxal phosphate-dependent enzyme low > 109
Paraburkholderia bryophila 376MFSha3.1 0.56 H281DRAFT_02409 glycine dehydrogenase 0.51 H281DRAFT_04680 hypothetical protein low > 103
Pseudomonas simiae WCS417 0.56 PS417_22360 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) 0.49 PS417_26725 hypothetical protein low > 88
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS19330 glycine cleavage system P protein (EC 1.4.4.2) (from data) 0.52 BPHYT_RS03495 hypothetical protein low > 109
Paraburkholderia graminis OAS925 0.56 ABIE53_000238 glycine dehydrogenase 0.52 ABIE53_000841 pyridoxal phosphate enzyme (YggS family) low > 113
Rhodanobacter denitrificans FW104-10B01 0.56 LRK54_RS00520 aminomethyl-transferring glycine dehydrogenase 0.25 LRK54_RS02905 YggS family pyridoxal phosphate-dependent enzyme low > 59
Paraburkholderia sabiae LMG 24235 0.55 QEN71_RS29215 aminomethyl-transferring glycine dehydrogenase 0.52 QEN71_RS26595 YggS family pyridoxal phosphate-dependent enzyme 0.46 36
Rhodopseudomonas palustris CGA009 0.55 TX73_019935 aminomethyl-transferring glycine dehydrogenase 0.29 TX73_014475 YggS family pyridoxal phosphate-dependent enzyme low > 86
Cupriavidus basilensis FW507-4G11 0.55 RR42_RS20070 glycine dehydrogenase 0.49 RR42_RS17355 hypothetical protein low > 128
Rhodanobacter sp. FW510-T8 0.55 OKGIIK_06740 gcvP2 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain 0.25 OKGIIK_09885 Pyridoxal phosphate homeostasis protein low > 52
Lysobacter sp. OAE881 0.55 ABIE51_RS14345 aminomethyl-transferring glycine dehydrogenase 0.44 ABIE51_RS16060 YggS family pyridoxal phosphate-dependent enzyme low > 62
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS08660 glycine dehydrogenase (aminomethyl-transferring) 0.46 RALBFv3_RS05575 YggS family pyridoxal phosphate-dependent enzyme 0.76 51
Ralstonia solanacearum UW163 0.55 UW163_RS04950 glycine dehydrogenase (aminomethyl-transferring) 0.46 UW163_RS08050 YggS family pyridoxal phosphate-dependent enzyme
Ralstonia solanacearum PSI07 0.55 RPSI07_RS08575 glycine dehydrogenase (aminomethyl-transferring) 0.45 RPSI07_RS11725 YggS family pyridoxal phosphate-dependent enzyme low > 81
Ralstonia solanacearum GMI1000 0.54 RS_RS16510 glycine dehydrogenase 0.47 RS_RS13435 YggS family pyridoxal phosphate-dependent enzyme 0.72 9
Ralstonia sp. UNC404CL21Col 0.54 ABZR87_RS03935 aminomethyl-transferring glycine dehydrogenase 0.48 ABZR87_RS01225 YggS family pyridoxal phosphate-dependent enzyme low > 80
Rhizobium sp. OAE497 0.54 ABIE40_RS09950 aminomethyl-transferring glycine dehydrogenase 0.26 ABIE40_RS19180 YggS family pyridoxal phosphate-dependent enzyme
Sinorhizobium meliloti 1021 0.54 SMc02049 glycine dehydrogenase 0.24 SMc02812 hypothetical protein 0.46 50
Castellaniella sp019104865 MT123 0.54 ABCV34_RS08835 aminomethyl-transferring glycine dehydrogenase 0.27 ABCV34_RS02955 YggS family pyridoxal phosphate-dependent enzyme low > 48
Xanthomonas campestris pv. campestris strain 8004 0.54 Xcc-8004.3878.1 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.43 Xcc-8004.1711.1 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.42 15
Variovorax sp. OAS795 0.54 ABID97_RS19655 aminomethyl-transferring glycine dehydrogenase 0.50 ABID97_RS00250 YggS family pyridoxal phosphate-dependent enzyme
Variovorax sp. SCN45 0.54 GFF6478 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.50 GFF3744 Pyridoxal phosphate-containing protein YggS
Mucilaginibacter yixingensis YX-36 DSM 26809 0.53 ABZR88_RS01785 aminomethyl-transferring glycine dehydrogenase 0.29 ABZR88_RS11740 YggS family pyridoxal phosphate-dependent enzyme low > 71
Phaeobacter inhibens DSM 17395 0.53 PGA1_78p00310 glycine dehydrogenase 0.25 PGA1_c33360 putative alanine racemase
Dinoroseobacter shibae DFL-12 0.53 Dshi_2680 glycine dehydrogenase (RefSeq) 0.32 Dshi_0042 alanine racemase domain protein (RefSeq) low > 64
Synechococcus elongatus PCC 7942 0.53 Synpcc7942_2047 gcvP glycine dehydrogenase 0.26 Synpcc7942_2060 ylmE hypothetical protein low > 38
Agrobacterium fabrum C58 0.53 Atu1462 glycine cleavage system protein P2 0.28 Atu2747 hypothetical protein 0.72 37
Acidovorax sp. GW101-3H11 0.52 Ac3H11_167 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.47 Ac3H11_4474 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 79
Pontibacter actiniarum KMM 6156, DSM 19842 0.52 CA264_18410 glycine dehydrogenase (aminomethyl-transferring) 0.28 CA264_06410 YggS family pyridoxal phosphate enzyme 0.31 53
Hydrogenophaga sp. GW460-11-11-14-LB1 0.52 GFF5215 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.49 GFF2722 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 90
Echinicola vietnamensis KMM 6221, DSM 17526 0.52 Echvi_0744 glycine dehydrogenase (decarboxylating) 0.25 Echvi_2233 pyridoxal phosphate enzyme, YggS family low > 79
Pedobacter sp. GW460-11-11-14-LB5 0.51 CA265_RS25185 glycine dehydrogenase (aminomethyl-transferring) 0.30 CA265_RS06285 YggS family pyridoxal phosphate enzyme low > 88
Mycobacterium tuberculosis H37Rv 0.50 Rv1832 Probable glycine dehydrogenase GcvB (glycine decarboxylase) (glycine cleavage system P-protein) 0.22 Rv2148c Conserved protein
Bacteroides ovatus ATCC 8483 0.48 BACOVA_04038 glycine dehydrogenase 0.27 BACOVA_00593 pyridoxal phosphate enzyme, YggS family low > 94
Parabacteroides merdae CL09T00C40 0.47 HMPREF1078_RS15115 aminomethyl-transferring glycine dehydrogenase 0.27 HMPREF1078_RS15965 YggS family pyridoxal phosphate-dependent enzyme low > 61
Bacteroides stercoris CC31F 0.47 HMPREF1181_RS16815 aminomethyl-transferring glycine dehydrogenase 0.26 HMPREF1181_RS10865 YggS family pyridoxal phosphate-dependent enzyme low > 56
Bacteroides thetaiotaomicron VPI-5482 0.47 BT1147 glycine dehydrogenase [decarboxylating] (NCBI ptt file) 0.26 BT1332 conserved hypothetical protein (NCBI ptt file) low > 81
Phocaeicola vulgatus CL09T03C04 0.46 HMPREF1058_RS18780 aminomethyl-transferring glycine dehydrogenase 0.25 HMPREF1058_RS06240 YggS family pyridoxal phosphate-dependent enzyme low > 67
Phocaeicola dorei CL03T12C01 0.46 ABI39_RS15100 aminomethyl-transferring glycine dehydrogenase 0.25 ABI39_RS20000 YggS family pyridoxal phosphate-dependent enzyme low > 72

Not shown: 0 genomes with orthologs for b2903 only; 16 genomes with orthologs for b2951 only