| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Sphingobium sp. HT1-2 | GFF4879 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | cofit | 100 | 100 |
| o | Rhodopseudomonas palustris CGA009 | TX73_011050 | | AMP-binding protein | insig. | 52 | 94 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF881 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 49 | 93 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS06225 | | AMP-binding protein | insig. | 50 | 95 |
| o | Variovorax sp. SCN45 | GFF6538 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 48 | 94 |
| o | Cupriavidus basilensis FW507-4G11 | RR42_RS29475 | | AMP-dependent synthetase | insig. | 46 | 92 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF5838 | | O-succinylbenzoic acid--CoA ligase (EC 6.2.1.26) | insig. | 34 | 91 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF5470 | | Benzoate-CoA ligase (EC 6.2.1.25) | insig. | 36 | 92 |
| o | Pseudomonas stutzeri RCH2 | Psest_2477 | | Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II | insig. | 34 | 94 |
| | Rhodopseudomonas palustris CGA009 | TX73_003840 | | long-chain fatty acid--CoA ligase | insig. | 35 | 92 |
| | Variovorax sp. SCN45 | GFF2647 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 34 | 91 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS16820 | | fatty-acid--CoA ligase | insig. | 35 | 91 |
| o | Caulobacter crescentus NA1000 | CCNA_01017 | | acyl-CoA synthetase | sig. | 36 | 91 |
| o | Caulobacter crescentus NA1000 Δfur | CCNA_01017 | | acyl-CoA synthetase | cofit | 36 | 91 |
| | Variovorax sp. SCN45 | GFF6539 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 33 | 88 |
| | Rhodopseudomonas palustris CGA009 | TX73_007245 | | long-chain fatty acid--CoA ligase | insig. | 35 | 90 |
| o | Azospirillum sp. SherDot2 | MPMX19_05315 | | Long-chain-fatty-acid--CoA ligase | insig. | 32 | 91 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2157 | | O-succinylbenzoic acid--CoA ligase (EC 6.2.1.26) | insig. | 33 | 91 |
| | Serratia liquefaciens MT49 | IAI46_12690 | | long-chain fatty acid--CoA ligase | insig. | 34 | 91 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS29385 | | long-chain fatty acid--CoA ligase | insig. | 35 | 91 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS26470 | | acyl-CoA synthetase | insig. | 34 | 92 |
| o | Dechlorosoma suillum PS | Dsui_2069 | | acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II | insig. | 35 | 91 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS36095 | | acyl-CoA synthetase | insig. | 34 | 93 |
| o | Pseudomonas sp. BP01 | JOY50_RS19660 | | fatty acid CoA ligase family protein | insig. | 32 | 93 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS24340 | | hypothetical protein | insig. | 34 | 89 |
| | Rhodopseudomonas palustris CGA009 | TX73_009065 | | fatty acid--CoA ligase | insig. | 33 | 92 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF5648 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 34 | 91 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS09890 | | acyl-CoA synthetase | insig. | 32 | 91 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS12470 | | long-chain fatty acid--CoA ligase | insig. | 33 | 91 |
| | Variovorax sp. SCN45 | GFF4321 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 33 | 91 |
| | Rhodopseudomonas palustris CGA009 | TX73_017055 | | long-chain fatty acid--CoA ligase | insig. | 32 | 91 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS36410 | | acyl-CoA synthetase | insig. | 32 | 91 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS09320 | | long-chain fatty acid--CoA ligase | insig. | 34 | 91 |
| o | Pseudomonas putida KT2440 | PP_2038 | | long-chain-fatty-acid--CoA ligase | insig. | 33 | 91 |
| | Variovorax sp. SCN45 | GFF2098 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 32 | 91 |
| o | Mycobacterium tuberculosis H37Rv | Rv3089 | | Probable chain-fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | insig. | 33 | 91 |
| | Rhodopseudomonas palustris CGA009 | TX73_006375 | | AMP-binding protein | insig. | 32 | 91 |
| o | Pseudomonas sp. S08-1 | OH686_06100 | | Long-chain-fatty-acid--CoA ligase | insig. | 32 | 91 |
| o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02398 | | fatty-acyl-CoA synthase | sig. | 31 | 93 |
| | Variovorax sp. SCN45 | GFF3376 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 31 | 91 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS29275 | | AMP-binding protein | insig. | 30 | 93 |
| | Pseudomonas sp. BP01 | JOY50_RS12405 | | class I adenylate-forming enzyme family protein | insig. | 32 | 92 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS26915 | | AMP-binding protein | strong | 29 | 92 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS29430 | | acyl-CoA synthetase | insig. | 35 | 87 |
| o | Paraburkholderia graminis OAS925 | ABIE53_000249 | | fatty-acyl-CoA synthase | sig. | 30 | 93 |
| | Azospirillum brasilense Sp245 | AZOBR_RS19340 | | long-chain fatty acid--CoA ligase | cofit | 33 | 91 |
| | Pseudomonas sp. BP01 | JOY50_RS02580 | | AMP-binding protein | insig. | 31 | 91 |
| o | Burkholderia phytofirmans PsJN | BPHYT_RS19375 | | AMP-binding protein | insig. | 31 | 93 |
| o | Variovorax sp. OAS795 | ABID97_RS18610 | | long-chain fatty acid--CoA ligase | insig. | 30 | 91 |
| | Variovorax sp. SCN45 | GFF2007 | | Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16) | insig. | 30 | 92 |
| | Paraburkholderia graminis OAS925 | ABIE53_001499 | | acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II | insig. | 29 | 91 |
| | Pseudomonas putida KT2440 | PP_3458 | | Butyrate--CoA ligase | sig. | 30 | 93 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_07945 | | AMP-binding protein | insig. | 30 | 91 |
| o | Pseudomonas segetis P6 | ACVTMO_RS05045 | | class I adenylate-forming enzyme family protein | insig. | 30 | 91 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS07325 | | AMP-binding protein | insig. | 30 | 93 |
| o | Pseudomonas sp. RS175 | PFR28_01261 | | 3-[(3aS,4S,7aS)-7a-methyl-1, 5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase | insig. | 30 | 91 |
| | Azospirillum sp. SherDot2 | MPMX19_03344 | | 3-[(3aS,4S,7aS)-7a-methyl-1, 5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase | insig. | 30 | 92 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0256 | | AMP-dependent synthetase and ligase (RefSeq) | sig. | 32 | 91 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS21845 | | AMP-binding protein | insig. | 30 | 91 |
| | Pseudomonas segetis P6 | ACVTMO_RS11790 | | AMP-binding protein | insig. | 29 | 93 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS11360 | | AMP-binding protein | sig. | 29 | 93 |
| | Ralstonia solanacearum UW163 | UW163_RS02225 | | AMP-binding protein | insig. | 29 | 93 |
| | Pseudomonas putida KT2440 | PP_4063 | | putative Long-chain-fatty-acid-CoA ligase | strong | 30 | 94 |
| | Ralstonia solanacearum GMI1000 | RS_RS02190 | | AMP-binding protein | insig. | 30 | 93 |
| | Mycobacterium tuberculosis H37Rv | Rv3561 | | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | sig. | 33 | 90 |
| o | Acinetobacter radioresistens SK82 | MPMX26_00552 | | Long-chain-fatty-acid--CoA ligase | insig. | 32 | 90 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03490 | | fatty-acyl-CoA synthase | insig. | 29 | 91 |
| | Variovorax sp. OAS795 | ABID97_RS28205 | | AMP-binding protein | no data | 35 | 83 |
| o | Rhodospirillum rubrum S1H | Rru_A1658 | | AMP-dependent synthetase and ligase (NCBI) | cofit | 33 | 90 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS08165 | | AMP-binding protein | insig. | 31 | 92 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS08400 | | AMP-binding protein | insig. | 31 | 92 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS23160 | | AMP-dependent synthetase | insig. | 31 | 91 |
| o | Xanthobacter sp. DMC5 | GFF496 | | Long-chain-fatty-acid--CoA ligase | insig. | 33 | 92 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1453 | fadD | long-chain-fatty-acid--CoA ligase (TIGR) | insig. | 32 | 90 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS12570 | | acyl-CoA synthetase | cofit | 32 | 92 |
| | Pseudomonas simiae WCS417 | PS417_17010 | | AMP-binding protein | insig. | 31 | 91 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF995 | | AMP-dependent synthetase/ligase in alkane synthesis cluster | insig. | 31 | 92 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03712 | | 3-[(3aS,4S,7aS)-7a-methyl-1, 5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase | insig. | 30 | 95 |
| | Azospirillum sp. SherDot2 | MPMX19_04176 | | Long-chain-fatty-acid--CoA ligase | insig. | 34 | 90 |
| | Pseudomonas sp. DMC3 | GFF1475 | | 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H- inden-4-yl]propanoyl:CoA ligase | cofit | 29 | 91 |
| o | Dinoroseobacter shibae DFL-12 | Dshi_0700 | | AMP-dependent synthetase and ligase (RefSeq) | insig. | 33 | 91 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2190 | | Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 30 | 91 |
| | Methanococcus maripaludis S2 | MMP_RS02990 | | AMP-binding protein | insig. | 30 | 91 |
| | Pseudomonas sp. BP01 | JOY50_RS03575 | | class I adenylate-forming enzyme family protein | insig. | 31 | 89 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_4064 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 32 | 91 |
| | Methanococcus maripaludis JJ | MMJJ_RS02080 | | AMP-binding protein | insig. | 30 | 91 |
| | Pseudomonas sp. BP01 | JOY50_RS06785 | | AMP-binding protein | insig. | 30 | 91 |
| o | Shewanella loihica PV-4 | Shew_2673 | caiC | putative crotonobetaine/carnitine-CoA ligase (RefSeq) | insig. | 32 | 92 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS27915 | | acyl-CoA synthetase | sig. | 32 | 91 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4967 | | Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 29 | 95 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_01575 | | AMP-binding protein | insig. | 30 | 91 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_2593 | | Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 29 | 91 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3009 | | Acetoacetate--CoA ligase (EC 6.2.1.16) (from data) | strong | 29 | 92 |
| | Azospirillum sp. SherDot2 | MPMX19_03572 | | Long-chain-fatty-acid--CoA ligase | insig. | 32 | 91 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2357 | | AMP-binding domain protein (RefSeq) | sig. | 30 | 92 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3988 | | Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 29 | 91 |
| | Rhodopseudomonas palustris CGA009 | TX73_018950 | | AMP-binding protein | insig. | 31 | 90 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0771 | | Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II | insig. | 30 | 92 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS18960 | | AMP-binding protein | cofit | 30 | 91 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS18960 | | AMP-binding protein | insig. | 30 | 91 |