Homologs of CSW01_10535 from Vibrio cholerae E7946 ATCC 55056

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC
SEED: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase

Top 100 hits from BLASTp (E < 0.01)

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Orth Species Gene Name Description Fitness %Id Cov
  Vibrio cholerae E7946 ATCC 55056 CSW01_10535 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC cofit 100 100
o Rahnella sp. WP5 EX31_RS19660 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 54 98
o Dickeya dianthicola ME23 DZA65_RS15420 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 53 99
o Escherichia coli ECOR27 NOLOHH_14275 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 53 99
o Escherichia coli Nissle 1917 ECOLIN_RS13465 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 53 99
o Escherichia fergusonii Becca EFB2_01534 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC insig. 53 99
o Dickeya dianthicola 67-19 HGI48_RS14485 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 53 99
o Escherichia coli BW25113 b2324 b2324 putative peptidase (VIMSS) sig. 53 99
o Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_01381 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC insig. 53 99
o Escherichia coli ECRC62 BNILDI_13195 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 52 99
o Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF1945 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase insig. 54 99
o Pectobacterium carotovorum WPP14 HER17_RS06960 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC cofit 52 99
o Escherichia coli BL21 ECD_02249 fused 5-methylaminomethyl-2-thiouridine-forming enzyme methyltransferase and FAD-dependent demodification enzyme insig. 53 99
o Serratia liquefaciens MT49 IAI46_18000 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 52 99
o Escherichia coli ECOR38 HEPCGN_21845 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 53 99
o Dickeya dadantii 3937 DDA3937_RS14515 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 52 99
o Escherichia coli ECRC100 OKFHMN_22640 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC cofit 52 99
o Escherichia coli ECRC101 MCAODC_13680 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 52 99
o Escherichia coli ECRC98 JDDGAC_26600 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 52 99
o Escherichia coli ECRC99 KEDOAH_05555 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC no data 52 99
o Enterobacter asburiae PDN3 EX28DRAFT_0280 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain insig. 53 99
o Escherichia coli ECRC102 NIAGMN_20415 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 52 99
o Enterobacter sp. TBS_079 MPMX20_03259 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC insig. 52 99
o Erwinia amylovora T8 OLJFJH_11180 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 51 99
o Klebsiella pneumoniae MKP103 KDGMDA_27245 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 53 99
o Klebsiella michiganensis M5al BWI76_RS20410 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 53 99
o Erwinia tracheiphila HP pepo 2.2 IJEDHG_17850 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC cofit 51 99
o Erwinia tracheiphila SCR3 LU632_RS07800 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 51 99
o Pantoea agglomerans CFBP13505 P0401 PagCFBP13505_RS00130 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC cofit 50 99
o Pantoea sp. MT58 IAI47_06175 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 50 99
o Alteromonas macleodii MIT1002 MIT1002_02542 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC cofit 38 97
o Pseudomonas sp. BP01 JOY50_RS16225 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 38 98
o Pseudomonas stutzeri RCH2 Psest_1634 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain sig. 39 98
o Pseudomonas sp. DMC3 GFF4698 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC cofit 38 99
o Pseudomonas syringae pv. syringae B728a Psyr_3742 FAD dependent oxidoreductase:Protein of unknown function DUF752 insig. 39 99
o Pseudomonas syringae pv. syringae B728a ΔmexB Psyr_3742 FAD dependent oxidoreductase:Protein of unknown function DUF752 insig. 39 99
o Pseudomonas simiae WCS417 PS417_19225 FAD-dependent cmnm(5)s(2)U34 oxidoreductase sig. 38 99
o Pseudomonas fluorescens GW456-L13 PfGW456L13_2155 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase sig. 38 98
o Pseudomonas lactucae CFBP13502 GEMAOFIL_02096 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC cofit 39 99
o Pseudomonas orientalis W4I3 QF045_RS21225 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 38 99
o Pseudomonas fluorescens FW300-N2E3 AO353_02165 FAD-dependent cmnm(5)s(2)U34 oxidoreductase sig. 38 98
o Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_373 5-methylaminomethyl-2-thiouridine-forming enzyme mnmC insig. 38 98
o Pseudomonas aeruginosa PUPa3 DQ20_RS41435 mnmC;go_function=tRNA bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 38 99
o Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_2541 5-methylaminomethyl-2-thiouridine-forming enzyme mnmC insig. 38 98
o Pseudomonas fluorescens FW300-N2C3 AO356_03570 FAD-dependent cmnm(5)s(2)U34 oxidoreductase insig. 38 98
o Pseudomonas aeruginosa PA14 IKLFDK_17740 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 38 99
o Pseudomonas aeruginosa MRSN321 DY961_RS15640 mnmC;go_function=tRNA bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 38 99
o Pseudomonas putida KT2440 PP_1751 methyltransferase/FAD-dependent oxidoreductase sig. 37 98
o Pseudomonas sp. RS175 PFR28_00884 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC insig. 37 98
o Pseudomonas sp. SVBP6 COO64_RS06835 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 37 98
o Pseudomonas sp. S08-1 OH686_20990 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase / FAD-dependent cmnm(5)s(2)U34 oxidoreductase cofit 37 99
o Pseudomonas segetis P6 ACVTMO_RS14220 mnmC bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 37 97
o Pseudomonas fluorescens SBW25 PFLU_RS21190 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC cofit 38 99
o Pseudomonas fluorescens SBW25-INTG PFLU_RS21190 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC sig. 38 99
o Marinobacter adhaerens HP15 HP15_1540 protein YfcK insig. 36 97
o Shewanella sp. ANA-3 Shewana3_1474 FAD dependent oxidoreductase (RefSeq) strong 34 90
o Paraburkholderia bryophila 376MFSha3.1 H281DRAFT_02360 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein insig. 34 98
o Paraburkholderia graminis OAS925 ABIE53_000291 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein insig. 33 98
o Dechlorosoma suillum PS Dsui_2868 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain protein insig. 34 98
  Shewanella amazonensis SB2B Sama_2155 glycine/D-amino acid oxidase (deaminating)-like protein (RefSeq) sig. 41 60
o Ralstonia sp. UNC404CL21Col ABZR87_RS12805 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 34 96
o Burkholderia phytofirmans PsJN BPHYT_RS19575 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC insig. 33 98
o Shewanella oneidensis MR-1 SO3073 conserved hypothetical protein (NCBI ptt file) insig. 33 90
o Ralstonia solanacearum PSI07 RPSI07_RS16115 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 32 97
o Ralstonia solanacearum GMI1000 RS_RS08635 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 33 97
o Methylophilus sp. DMC18 GFF715 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC insig. 34 97
o Ralstonia solanacearum IBSBF1503 RALBFv3_RS01360 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 33 96
o Ralstonia solanacearum UW163 UW163_RS14670 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 33 96
o Paraburkholderia sabiae LMG 24235 QEN71_RS29485 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 33 98
  Shewanella loihica PV-4 Shew_2411 FAD dependent oxidoreductase (RefSeq) insig. 39 60
o Acinetobacter radioresistens SK82 MPMX26_02642 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC insig. 31 97
o Acinetobacter baumannii LAC-4 RR41_RS02870 FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 31 97
o Cupriavidus basilensis FW507-4G11 RR42_RS09010 FAD-dependent cmnm(5)s(2)U34 oxidoreductase insig. 32 98
o Castellaniella sp019104865 MT123 ABCV34_RS09580 FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 32 95
o Brevundimonas sp. GW460-12-10-14-LB2 A4249_RS15340 tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD insig. 31 96
o Herbaspirillum seropedicae SmR1 HSERO_RS23825 hypothetical protein insig. 29 89
o Kangiella aquimarina DSM 16071 B158DRAFT_1306 Uncharacterized conserved protein insig. 28 95
o Variovorax sp. OAS795 ABID97_RS15455 FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC insig. 30 97
o Acidovorax sp. GW101-3H11 Ac3H11_579 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase insig. 32 96
o Variovorax sp. SCN45 GFF1245 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase insig. 30 96
o Caulobacter crescentus NA1000 CCNA_00785 tRNA methyltransferase/FAD-dependent oxidoreductase MnmC sig. 28 95
o Caulobacter crescentus NA1000 Δfur CCNA_00785 tRNA methyltransferase/FAD-dependent oxidoreductase MnmC cofit 28 95
  Phaeobacter inhibens DSM 17395 PGA1_c28960 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC-like protein insig. 45 35
  Agrobacterium fabrum C58 Atu2331 hypothetical protein insig. 37 35
  Dinoroseobacter shibae DFL-12 Dshi_0152 protein of unknown function DUF752 (RefSeq) insig. 40 36
  Sinorhizobium meliloti 1021 SM_b20878 hypothetical protein insig. 37 36
  Rhizobium sp. OAE497 ABIE40_RS13870 tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD insig. 36 36
  Parabacteroides merdae CL09T00C40 HMPREF1078_RS12120 tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD insig. 30 32
  Phocaeicola vulgatus CL09T03C04 HMPREF1058_RS11010 tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD insig. 29 33
  Phocaeicola dorei CL03T12C01 ABI39_RS06040 tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD insig. 29 33
  Shewanella loihica PV-4 Shew_3321 hypothetical protein (RefSeq) insig. 26 34
  Pedobacter sp. GW460-11-11-14-LB5 CA265_RS14330 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase insig. 25 35
  Pontibacter actiniarum KMM 6156, DSM 19842 CA264_15900 SAM-dependent methyltransferase insig. 26 35
  Bacteroides ovatus ATCC 8483 BACOVA_01345 hypothetical protein sig. 28 27
  Echinicola vietnamensis KMM 6221, DSM 17526 Echvi_1505 Uncharacterized conserved protein cofit 28 33
  Bacteroides thetaiotaomicron VPI-5482 BT3250 conserved hypothetical protein (NCBI ptt file) sig. 29 27
  Hydrogenophaga sp. GW460-11-11-14-LB1 GFF4296 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase insig. 24 56
  Cellulophaga baltica 18 M666_RS19245 tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD insig. 26 28
  Bacteroides stercoris CC31F HMPREF1181_RS01595 tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD insig. 27 28
  Synechocystis sp000284455 PCC 6803 SGL_RS04970 tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD cofit 29 32