| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Agrobacterium fabrum C58 | Atu2419 | | transcriptional regulator, LuxR family | insig. | 100 | 100 |
| o | Rhizobium sp. OAE497 | ABIE40_RS14675 | | response regulator transcription factor | insig. | 81 | 98 |
| o | Sinorhizobium meliloti 1021 | SM_b20610 | | two-component response regulator protein | insig. | 79 | 98 |
| o | Rhodopseudomonas palustris CGA009 | TX73_006410 | | response regulator transcription factor | insig. | 56 | 93 |
| o | Azospirillum sp. SherDot2 | MPMX19_04589 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 53 | 95 |
| | Azospirillum sp. SherDot2 | MPMX19_04108 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 55 | 96 |
| o | Marinobacter adhaerens HP15 | HP15_3660 | | two-component response regulator | insig. | 50 | 91 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS22750 | | response regulator transcription factor | insig. | 45 | 92 |
| o | Variovorax sp. SCN45 | GFF638 | | Two-component transcriptional response regulator, LuxR family | insig. | 48 | 93 |
| o | Herbaspirillum seropedicae SmR1 | HSERO_RS13200 | | transcriptional regulator | insig. | 46 | 95 |
| o | Methylophilus sp. DMC18 | GFF1954 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | cofit | 42 | 94 |
| | Variovorax sp. SCN45 | GFF2488 | | Two-component transcriptional response regulator, LuxR family | insig. | 46 | 94 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3270 | | Two-component response regulator | insig. | 43 | 96 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_3695 | | Two-component response regulator | sig. | 45 | 96 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2878 | | Two-component response regulator | insig. | 43 | 98 |
| o | Variovorax sp. OAS795 | ABID97_RS23505 | | response regulator transcription factor | insig. | 42 | 94 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS12370 | | response regulator transcription factor | insig. | 57 | 42 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS12370 | | response regulator transcription factor | insig. | 57 | 42 |
| | Pseudomonas simiae WCS417 | PS417_11585 | | LuxR family transcriptional regulator | insig. | 57 | 42 |
| | Pseudomonas sp. S08-1 | OH686_16560 | | Two-component transcriptional response regulator, LuxR family | insig. | 56 | 41 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_181 | | Two-component response regulator | insig. | 51 | 48 |
| | Pseudomonas segetis P6 | ACVTMO_RS02300 | | response regulator | insig. | 51 | 43 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS32075 | | response regulator | insig. | 46 | 47 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS30905 | | histidine kinase | insig. | 47 | 40 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03106 | | PAS domain S-box-containing protein | insig. | 48 | 38 |
| | Paraburkholderia graminis OAS925 | ABIE53_004192 | | PAS domain S-box-containing protein | strong | 48 | 38 |
| | Marinobacter adhaerens HP15 | HP15_1054 | | multi-sensor signal transduction histidine kinase | strong | 36 | 53 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS18655 | | response regulator | insig. | 46 | 39 |
| | Alteromonas macleodii MIT1002 | MIT1002_00763 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 42 | 45 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4352 | | Response regulator | insig. | 47 | 40 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03320 | | EAL domain-containing protein | insig. | 42 | 40 |
| | Pseudomonas sp. S08-1 | OH686_00410 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 49 | 40 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS11870 | | AraC family transcriptional regulator | insig. | 46 | 40 |
| | Sphingobium sp. HT1-2 | GFF2748 | | Pole remodelling regulatory diguanylate cyclase | cofit | 45 | 39 |
| | Paraburkholderia graminis OAS925 | ABIE53_004362 | | DNA-binding response OmpR family regulator | insig. | 44 | 40 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03035 | | diguanylate cyclase | sig. | 42 | 42 |
| | Azospirillum sp. SherDot2 | MPMX19_02025 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 43 | 39 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS06860 | | AraC family transcriptional regulator | sig. | 41 | 42 |
| | Shewanella loihica PV-4 | Shew_3199 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 44 | 38 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS08635 | | response regulator | sig. | 35 | 51 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS34710 | | chemotaxis protein CheY | insig. | 45 | 38 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS03625 | | response regulator | insig. | 42 | 38 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09310 | | two-component system response regulator | insig. | 42 | 42 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2270 | | Pole remodelling regulatory diguanylate cyclase | insig. | 41 | 43 |
| | Azospirillum sp. SherDot2 | MPMX19_06045 | | putative cyclic di-GMP phosphodiesterase | insig. | 45 | 40 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06795 | | two-component system response regulator | insig. | 41 | 39 |
| | Shewanella amazonensis SB2B | Sama_2951 | | response regulator receiver protein (RefSeq) | insig. | 42 | 38 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2310 | | Pole remodelling regulatory diguanylate cyclase | insig. | 42 | 42 |
| | Shewanella sp. ANA-3 | Shewana3_0479 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 42 | 41 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS12050 | | response regulator | insig. | 40 | 36 |
| | Rhodopseudomonas palustris CGA009 | TX73_016195 | | PleD family two-component system response regulator | insig. | 45 | 37 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09200 | | two-component system response regulator | cofit | 42 | 38 |
| | Azospirillum sp. SherDot2 | MPMX19_02587 | | Phosphate regulon transcriptional regulatory protein PhoB | cofit | 39 | 52 |
| | Azospirillum brasilense Sp245 | AZOBR_RS01105 | | PhoB family transcriptional regulator | insig. | 37 | 52 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS20960 | | two-component system response regulator | cofit | 43 | 42 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09195 | | hybrid sensor histidine kinase/response regulator | insig. | 45 | 38 |
| | Pseudomonas sp. S08-1 | OH686_07455 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 43 | 42 |
| | Alteromonas macleodii MIT1002 | MIT1002_01768 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 43 | 38 |
| | Sinorhizobium meliloti 1021 | SMc01370 | | response regulator PleD | insig. | 43 | 38 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09305 | | two-component system response regulator | insig. | 40 | 42 |
| | Dechlorosoma suillum PS | Dsui_0777 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 40 | 42 |
| | Shewanella oneidensis MR-1 | SO4003 | | response regulator (NCBI ptt file) | insig. | 35 | 72 |
| | Shewanella loihica PV-4 | Shew_0979 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | insig. | 36 | 53 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4666 | | Sensory box/GGDEF family protein | insig. | 32 | 58 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1097 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 45 | 39 |
| | Azospirillum brasilense Sp245 | AZOBR_RS16180 | | diguanylate cyclase | strong | 42 | 37 |
| | Shewanella sp. ANA-3 | Shewana3_3418 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 38 | 38 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1538 | | two component transcriptional regulator, winged helix family (RefSeq) | no data | 40 | 39 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_13725 | | diguanylate cyclase | insig. | 32 | 57 |
| | Pseudomonas stutzeri RCH2 | Psest_1725 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 42 | 37 |
| | Pseudomonas sp. DMC3 | GFF2455 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | cofit | 43 | 39 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3644 | | Pole remodelling regulatory diguanylate cyclase | insig. | 42 | 42 |
| | Shewanella loihica PV-4 | Shew_3790 | | response regulator receiver modulated diguanylate cyclase (RefSeq) | insig. | 38 | 46 |
| | Shewanella amazonensis SB2B | Sama_3594 | | response regulator receiver protein (RefSeq) | insig. | 34 | 58 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c15730 | | phosphate regulon transcriptional regulatory protein PhoB | strong | 40 | 44 |
| | Azospirillum sp. SherDot2 | MPMX19_01522 | | Response regulator PleD | insig. | 42 | 37 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14285 | | transcriptional regulator | strong | 44 | 38 |
| | Rhizobium sp. OAE497 | ABIE40_RS07330 | | PleD family two-component system response regulator | cofit | 43 | 37 |
| | Shewanella sp. ANA-3 | Shewana3_0481 | | response regulator receiver protein (RefSeq) | cofit | 40 | 37 |
| | Pseudomonas segetis P6 | ACVTMO_RS19850 | | HD domain-containing phosphohydrolase | insig. | 44 | 38 |
| | Agrobacterium fabrum C58 | Atu1297 | | two component response regulator | insig. | 45 | 37 |
| | Azospirillum sp. SherDot2 | MPMX19_01958 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 44 | 38 |
| | Dechlorosoma suillum PS | Dsui_0331 | | PAS domain S-box | insig. | 42 | 37 |
| | Shewanella sp. ANA-3 | Shewana3_3334 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 36 | 46 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3451 | | Response regulator receiver:ATP-binding region, ATPase-like:Stage II sporulation E | insig. | 43 | 38 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3451 | | Response regulator receiver:ATP-binding region, ATPase-like:Stage II sporulation E | insig. | 43 | 38 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS02130 | | hybrid sensor histidine kinase/response regulator | strong | 38 | 38 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS09450 | | response regulator transcription factor | insig. | 38 | 39 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_03275 | | hybrid sensor histidine kinase/response regulator | insig. | 36 | 39 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS05185 | | response regulator | insig. | 42 | 40 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4137 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 39 | 38 |
| | Shewanella oneidensis MR-1 | SO0860 | | response regulator (NCBI ptt file) | insig. | 37 | 38 |
| | Azospirillum brasilense Sp245 | AZOBR_RS03050 | | diguanylate cyclase | sig. | 38 | 42 |
| | Shewanella amazonensis SB2B | Sama_3111 | | response regulator receiver protein (RefSeq) | insig. | 42 | 39 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS00130 | hsbR;inference=COORDINATES | two-component system response regulator HsbR | sig. | 42 | 38 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_17155 | | two-component system response regulator HsbR | sig. | 42 | 38 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS40880 | hsbR;inference=COORDINATES | two-component system response regulator HsbR | insig. | 42 | 38 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS11205 | | hybrid sensor histidine kinase/response regulator | insig. | 40 | 37 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS11200 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 38 | 38 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS00270 | | response regulator | cofit | 33 | 45 |
| | Azospirillum brasilense Sp245 | AZOBR_RS22685 | | response regulator PleD (with diguanylate cyclase and response regulator receiver domains) (fragment) | insig. | 43 | 36 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4347 | | Serine phosphatase RsbU, regulator of sigma subunit | insig. | 42 | 38 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS28055 | | EAL domain-containing protein | insig. | 31 | 59 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS28055 | | EAL domain-containing protein | sig. | 31 | 59 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03092 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | cofit | 39 | 37 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_18710 | | chemotaxis protein CheY | sig. | 42 | 37 |
| | Dechlorosoma suillum PS | Dsui_3468 | | Response regulator receiver domain protein,histidine kinase | cofit | 38 | 44 |
| | Shewanella amazonensis SB2B | Sama_0748 | | response regulator receiver protein (RefSeq) | sig. | 33 | 41 |
| | Shewanella amazonensis SB2B | Sama_0065 | | response regulator receiver protein (RefSeq) | insig. | 43 | 38 |
| | Pseudomonas simiae WCS417 | PS417_19775 | | chemotaxis protein CheY | insig. | 42 | 36 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0046 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | sig. | 39 | 39 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS06935 | | phosphate regulon transcriptional regulatory protein PhoB | insig. | 33 | 55 |
| | Shewanella sp. ANA-3 | Shewana3_4015 | | response regulator receiver modulated diguanylate cyclase (RefSeq) | cofit | 38 | 37 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS15265 | | EAL domain-containing response regulator | insig. | 38 | 37 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15265 | | EAL domain-containing response regulator | insig. | 38 | 37 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2405 | | Sensory box/GGDEF family protein | insig. | 32 | 57 |
| | Pseudomonas simiae WCS417 | PS417_11585 | | LuxR family transcriptional regulator | insig. | 65 | 22 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS21745 | | fused response regulator/phosphatase | insig. | 42 | 36 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS21745 | | fused response regulator/phosphatase | sig. | 42 | 36 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS15805 | | two component system response regulator RpaA | strong | 34 | 41 |
| | Pseudomonas orientalis W4I3 | QF045_RS16400 | | EAL domain-containing response regulator | insig. | 39 | 39 |
| | Pseudomonas sp. S08-1 | OH686_02805 | | Serine phosphatase RsbU, regulator of sigma subunit / Serine-protein kinase RsbW | cofit | 44 | 36 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1635 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 38 | 40 |
| | Pseudomonas sp. DMC3 | GFF149 | | Sensor histidine kinase RcsC | cofit | 31 | 57 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS12370 | | response regulator transcription factor | insig. | 72 | 19 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS12370 | | response regulator transcription factor | insig. | 72 | 19 |
| | Dechlorosoma suillum PS | Dsui_3287 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 40 | 40 |
| | Dechlorosoma suillum PS | Dsui_3334 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 43 | 40 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03096 | | response regulator receiver domain protein | cofit | 38 | 36 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_07885 | | diguanylate cyclase | strong | 31 | 57 |
| | Pseudomonas protegens RBAN4 | FABNJH_08545 | | Response regulator | insig. | 42 | 37 |
| | Azospirillum brasilense Sp245 | AZOBR_RS22690 | | sensor protein | insig. | 41 | 45 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4462 | | Serine phosphatase RsbU, regulator of sigma subunit | insig. | 40 | 44 |
| | Pseudomonas sp. S08-1 | OH686_23615 | | Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY | insig. | 40 | 40 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1822 | | sensor histidine kinase | insig. | 39 | 42 |
| | Azospirillum sp. SherDot2 | MPMX19_00501 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 39 | 39 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14305 | | transcriptional regulator | cofit | 38 | 39 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS00635 | | substrate-binding domain-containing protein | strong | 33 | 40 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1873 | | two component transcriptional regulator, winged helix family | insig. | 33 | 45 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS31505 | | response regulator | insig. | 42 | 38 |
| | Pseudomonas sp. RS175 | PFR28_01483 | | Sensor histidine kinase RcsC | insig. | 40 | 40 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS15110 | | response regulator | insig. | 36 | 40 |
| | Bifidobacterium breve UCC2003 | BBR_RS17455 | | DNA-binding response regulator | strong | 36 | 43 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_0095 | rpaA | two component transcriptional regulator, winged helix family | strong | 36 | 42 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS06700 | | response regulator | insig. | 35 | 37 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1058 | | two-component system sensor histidine kinase (NCBI ptt file) | strong | 32 | 56 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS08350 | | PleD family two-component system response regulator | insig. | 48 | 29 |
| | Pseudomonas putida KT2440 | PP_4363 | | Sensor histidine kinase/response regulator | sig. | 42 | 37 |
| | Pseudomonas sp. RS175 | PFR28_00838 | | Sensor histidine kinase RcsC | sig. | 41 | 37 |
| | Azospirillum sp. SherDot2 | MPMX19_01858 | | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP | insig. | 39 | 38 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1083 | phoB | phosphate regulon transcriptional regulator PhoB (TIGR) | no data | 39 | 41 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS20605 | | response regulator | insig. | 38 | 38 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS06810 | | response regulator | insig. | 38 | 38 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_19685 | | DNA-binding response regulator | insig. | 38 | 36 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04086 | | response regulator receiver domain protein | insig. | 32 | 56 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS08240 | | substrate-binding domain-containing protein | strong | 31 | 42 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_05407 | | putative signaling protein | cofit | 30 | 59 |
| | Pseudomonas sp. S08-1 | OH686_16560 | | Two-component transcriptional response regulator, LuxR family | insig. | 67 | 21 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_03805 | | chemotaxis protein CheY | sig. | 42 | 37 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS10050 | | response regulator | insig. | 35 | 37 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS09180 | | DNA-binding response regulator | no data | 36 | 36 |
| | Bosea sp. OAE506 | ABIE41_RS18170 | | PleD family two-component system response regulator | insig. | 41 | 37 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_29430 | | histidine kinase | insig. | 41 | 39 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04153 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | cofit | 40 | 40 |
| | Azospirillum sp. SherDot2 | MPMX19_01957 | | Sensor histidine kinase RcsC | insig. | 40 | 38 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1098 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) | insig. | 38 | 37 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1098 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) | insig. | 38 | 37 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS15245 | | response regulator | insig. | 36 | 38 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c34880 | | putative response regulator | strong | 42 | 36 |
| | Pseudomonas sp. SVBP6 | COO64_RS21250 | | fused response regulator/phosphatase | insig. | 42 | 37 |
| | Pseudomonas orientalis W4I3 | QF045_RS21905 | | fused response regulator/phosphatase | cofit | 40 | 40 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0732 | | two-component system response regulator (NCBI ptt file) | no data | 36 | 41 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2622 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 37 | 40 |
| | Pseudomonas segetis P6 | ACVTMO_RS02300 | | response regulator | insig. | 74 | 17 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS13565 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 41 | 39 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS31465 | | diguanylate cyclase | insig. | 41 | 39 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2820 | | response regulator receiver modulated diguanylate cyclase (RefSeq) | sig. | 40 | 37 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS14215 | | hypothetical protein | insig. | 38 | 41 |
| | Variovorax sp. SCN45 | GFF5870 | | hypothetical protein | cofit | 35 | 47 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14200 | | chemotaxis protein CheY | strong | 35 | 40 |
| | Pseudomonas sp. BP01 | JOY50_RS00655 | | fused response regulator/phosphatase | insig. | 42 | 37 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2271 | | Response regulator | insig. | 40 | 38 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2587 | | Serine phosphatase RsbU, regulator of sigma subunit | strong | 39 | 39 |
| | Methylophilus sp. DMC18 | GFF2576 | | Phosphate regulon transcriptional regulatory protein PhoB | cofit | 38 | 44 |
| | Mycobacterium tuberculosis H37Rv | Rv0757 | | Possible two component system response transcriptional positive regulator PhoP | sig. | 40 | 40 |
| | Alteromonas macleodii MIT1002 | MIT1002_01584 | | Stalked cell differentiation-controlling protein | insig. | 40 | 38 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3610 | | Serine phosphatase RsbU, regulator of sigma subunit | insig. | 40 | 37 |
| | Pseudomonas sp. S08-1 | OH686_23605 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 38 | 38 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4346 | | Signal transduction histidine kinase | insig. | 36 | 40 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04371 | | response regulator receiver domain protein | insig. | 35 | 39 |
| | Pseudomonas orientalis W4I3 | QF045_RS00790 | | EAL domain-containing protein | cofit | 30 | 58 |
| | Pseudomonas protegens RBAN4 | FABNJH_29130 | | Two-component system response regulator | insig. | 30 | 59 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS11140 | | response regulator | insig. | 41 | 38 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS11140 | | response regulator | insig. | 41 | 38 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS52375 | | cyclic di-GMP phosphodiesterase | insig. | 40 | 42 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0882 | | two component transcriptional regulator, winged helix family (RefSeq) | strong | 39 | 40 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3172 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 35 | 38 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS09670 | | cyclic di-GMP phosphodiesterase | sig. | 42 | 39 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_29680 | | cyclic di-GMP phosphodiesterase | insig. | 42 | 39 |
| | Azospirillum sp. SherDot2 | MPMX19_04596 | | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP | insig. | 41 | 38 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS08970 | | phosphate regulon transcriptional regulator PhoB | no data | 41 | 39 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02182 | | response regulator receiver domain protein | cofit | 36 | 37 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS11130 | | two-component regulator propeller domain-containing protein | cofit | 35 | 42 |
| | Sinorhizobium meliloti 1021 | SM_b20357 | | histidine kinase | insig. | 40 | 36 |
| | Klebsiella pneumoniae MRSN742743 | KFA93_RS14860 | | response regulator | insig. | 32 | 59 |
| | Caulobacter crescentus NA1000 | CCNA_02546 | | GGDEF/response regulator protein PleD | strong | 42 | 37 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02546 | | GGDEF/response regulator protein PleD | cofit | 42 | 37 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01673 | | response regulator receiver domain protein | insig. | 37 | 40 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2971 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 36 | 39 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_22510 | | DNA-binding response regulator | insig. | 32 | 59 |
| | Marinobacter adhaerens HP15 | HP15_2320 | | response regulator receiver protein | insig. | 40 | 40 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1817 | ltnA | response regulator receiver domain protein (CheY-like) | insig. | 39 | 36 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_22360 | | chemotaxis protein CheY | insig. | 33 | 61 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS17305 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 33 | 41 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1071 | | Sensory box/GGDEF family protein | insig. | 30 | 57 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS04350 | | PleD family two-component system response regulator | sig. | 41 | 39 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_2939 | | response regulator receiver modulated diguanylate cyclase | no data | 43 | 39 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2939 | | response regulator receiver modulated diguanylate cyclase | no data | 43 | 39 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_28575 | | transcriptional regulator | insig. | 39 | 37 |
| | Sphingobium sp. HT1-2 | GFF2657 | | Phosphate regulon transcriptional regulatory protein PhoB (SphR) | cofit | 32 | 64 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09695 | | hybrid sensor histidine kinase/response regulator | strong | 40 | 32 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS15170 | | response regulator | insig. | 33 | 44 |
| | Pseudomonas putida KT2440 | PP_4959 | | diguanylate cyclase | cofit | 30 | 55 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02438 | | response regulator receiver domain protein | insig. | 34 | 49 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02886 | | Sensor histidine kinase RcsC | insig. | 37 | 39 |
| | Caulobacter crescentus NA1000 | CCNA_00296 | | phosphate regulon response regulator PhoB | strong | 36 | 39 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00296 | | phosphate regulon response regulator PhoB | cofit | 36 | 39 |
| | Pseudomonas sp. S08-1 | OH686_00995 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 36 | 42 |
| | Cellulophaga baltica 18 | M666_RS09795 | | two-component regulator propeller domain-containing protein | insig. | 34 | 37 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4236 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 33 | 43 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_181 | | Two-component response regulator | insig. | 67 | 19 |
| | Escherichia coli ECOR38 | HEPCGN_22430 | atoC | acetoacetate metabolism transcriptional regulator AtoC | insig. | 38 | 35 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS01480 | | two-component system response regulator | insig. | 36 | 39 |
| | Dechlorosoma suillum PS | Dsui_2782 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | no data | 36 | 42 |
| | Pseudomonas sp. RS175 | PFR28_00263 | | HTH-type transcriptional activator RhaR | insig. | 35 | 40 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS05670 | | substrate-binding domain-containing protein | strong | 34 | 39 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS00710 | | hypothetical protein | insig. | 34 | 42 |
| | Shewanella amazonensis SB2B | Sama_1718 | | response regulator receiver protein (RefSeq) | strong | 41 | 37 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02648 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | cofit | 34 | 43 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3651 | | phosphate regulon transcriptional regulatory protein PhoB | no data | 39 | 39 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS04660 | | response regulator | cofit | 36 | 38 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02757 | | response regulator receiver domain protein | insig. | 33 | 37 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS03105 | | response regulator transcription factor | strong | 33 | 39 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4124 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 31 | 50 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_342 | | DNA-binding response regulator | insig. | 39 | 44 |
| | Acinetobacter baumannii LAC-4 | RR41_RS00505 | | phosphate regulon transcriptional regulator PhoB | cofit | 37 | 44 |
| | Acinetobacter radioresistens SK82 | MPMX26_02958 | | Phosphate regulon transcriptional regulatory protein PhoB | strong | 36 | 44 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS09900 | | two-component regulator propeller domain-containing protein | insig. | 36 | 39 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS04725 | | response regulator transcription factor | strong | 33 | 39 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS10925 | | response regulator | insig. | 32 | 44 |