| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Shewanella amazonensis SB2B | Sama_1183 | | alpha/beta fold family hydrolase (RefSeq) | sig. | 100 | 100 |
| o | Shewanella sp. ANA-3 | Shewana3_2714 | | alpha/beta hydrolase fold (RefSeq) | insig. | 67 | 97 |
| o | Shewanella oneidensis MR-1 | SO1743 | | hydrolase, alpha/beta hydrolase fold family (NCBI ptt file) | strong | 67 | 98 |
| o | Shewanella loihica PV-4 | Shew_1714 | | alpha/beta hydrolase fold (RefSeq) | strong | 62 | 95 |
| o | Lysobacter sp. OAE881 | ABIE51_RS00260 | | alpha/beta fold hydrolase | cofit | 53 | 94 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.287.1 | | Haloalkane dehalogenase-like protein | sig. | 50 | 90 |
| o | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_05120 | | alpha/beta hydrolase | insig. | 33 | 97 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_13415 | | alpha/beta hydrolase | sig. | 29 | 96 |
| o | Mycobacterium tuberculosis H37Rv | Rv1833c | | Possible haloalkane dehalogenase | insig. | 27 | 94 |
| o | Paraburkholderia graminis OAS925 | ABIE53_004339 | | pimeloyl-ACP methyl ester carboxylesterase | insig. | 29 | 91 |
| | Mycobacterium tuberculosis H37Rv | Rv2296 | | Probable haloalkane dehalogenase | insig. | 29 | 86 |
| o | Marinobacter adhaerens HP15 | HP15_2669 | | alpha/beta hydrolase fold protein | cofit | 29 | 91 |
| | Paraburkholderia graminis OAS925 | ABIE53_006204 | | pimeloyl-ACP methyl ester carboxylesterase | insig. | 29 | 84 |
| o | Xanthobacter sp. DMC5 | GFF1208 | | Haloalkane dehalogenase | insig. | 27 | 92 |
| o | Cellulophaga baltica 18 | M666_RS15980 | | alpha/beta hydrolase | insig. | 28 | 84 |
| | Marinobacter adhaerens HP15 | HP15_590 | | haloalkane dehalogenase | insig. | 28 | 87 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_554 | | tRNA-specific adenosine-34 deaminase (EC 3.5.4.-) / domain of unknown function | no data | 29 | 89 |
| o | Synechococcus elongatus PCC 7942 | Synpcc7942_0901 | | Haloalkane dehalogenase | insig. | 27 | 84 |
| o | Caulobacter crescentus NA1000 | CCNA_01233 | | haloalkane dehalogenase | sig. | 27 | 89 |
| o | Caulobacter crescentus NA1000 Δfur | CCNA_01233 | | haloalkane dehalogenase | cofit | 27 | 89 |
| o | Pseudomonas sp. S08-1 | OH686_04220 | | 3-Oxoadipate enol-lactonase, alpha/beta hydrolase fold family | cofit | 26 | 90 |
| o | Pseudomonas segetis P6 | MPMX49_03664 | | Haloalkane dehalogenase | insig. | 28 | 94 |
| o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01802 | | Pimeloyl-ACP methyl ester carboxylesterase | insig. | 28 | 88 |
| o | Paraburkholderia sabiae LMG 24235 | QEN71_RS36555 | | alpha/beta hydrolase | insig. | 27 | 93 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_413 | | N-formylglutamate deformylase (EC 3.5.1.68) | insig. | 28 | 93 |
| o | Sinorhizobium meliloti 1021 | SMc03098 | | hypothetical protein | insig. | 27 | 94 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03034 | | Cis-3-alkyl-4-alkyloxetan-2-one decarboxylase | cofit | 26 | 84 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_05188 | | Pimeloyl-ACP methyl ester carboxylesterase | insig. | 25 | 93 |
| o | Burkholderia phytofirmans PsJN | BPHYT_RS11420 | | alpha/beta hydrolase | insig. | 24 | 93 |
| | Pseudomonas segetis P6 | MPMX49_02129 | | Lipase 3 | insig. | 27 | 92 |
| o | Sphingobium sp. HT1-2 | GFF3488 | | Hydrolase, alpha/beta fold family | cofit | 26 | 84 |
| | Xanthobacter sp. DMC5 | GFF1209 | | Cis-3-alkyl-4-alkyloxetan-2-one decarboxylase | insig. | 28 | 90 |
| | Pseudomonas sp. S08-1 | OH686_23220 | | Alpha/beta hydrolase fold | insig. | 27 | 87 |
| | Mycobacterium tuberculosis H37Rv | Rv2715 | | Possible hydrolase | insig. | 24 | 85 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01784 | | Pimeloyl-ACP methyl ester carboxylesterase | insig. | 26 | 84 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4700 | | tRNA-specific adenosine-34 deaminase (EC 3.5.4.-) / domain of unknown function | insig. | 26 | 91 |
| o | Agrobacterium fabrum C58 | Atu6064 | | haloalkane dehalogenase | insig. | 26 | 87 |
| | Paraburkholderia graminis OAS925 | ABIE53_002365 | | pimeloyl-ACP methyl ester carboxylesterase | insig. | 24 | 95 |
| | Pseudomonas sp. S08-1 | OH686_05690 | | Putative hydrolase | insig. | 27 | 90 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_15000 | | alpha/beta hydrolase | insig. | 25 | 86 |
| o | Variovorax sp. OAS795 | ABID97_RS22225 | | alpha/beta hydrolase | insig. | 25 | 93 |
| o | Cupriavidus basilensis FW507-4G11 | RR42_RS11030 | | alpha/beta hydrolase | insig. | 26 | 87 |
| o | Ralstonia solanacearum PSI07 | RPSI07_RS16400 | | alpha/beta hydrolase | insig. | 25 | 90 |
| | Mycobacterium tuberculosis H37Rv | Rv2579 | | Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) | insig. | 25 | 92 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS12530 | | alpha/beta hydrolase | insig. | 25 | 90 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_03640 | | alpha/beta hydrolase | insig. | 24 | 92 |
| o | Ralstonia solanacearum GMI1000 | RS_RS08940 | | alpha/beta hydrolase | insig. | 25 | 90 |
| | Serratia liquefaciens MT49 | IAI46_11940 | | alpha/beta hydrolase | insig. | 34 | 47 |
| o | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS01075 | | alpha/beta hydrolase | sig. | 26 | 90 |
| o | Ralstonia solanacearum UW163 | UW163_RS14385 | | alpha/beta hydrolase | insig. | 26 | 90 |
| | Lysobacter sp. OAE881 | ABIE51_RS03110 | | alpha/beta hydrolase | cofit | 25 | 85 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS07150 | | alpha/beta hydrolase | insig. | 24 | 94 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS37525 | | alpha/beta hydrolase | insig. | 27 | 86 |
| | Lysobacter sp. OAE881 | ABIE51_RS16175 | | alpha/beta hydrolase | insig. | 34 | 44 |
| | Cellulophaga baltica 18 | M666_RS15975 | | alpha/beta hydrolase | insig. | 25 | 96 |
| o | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS14160 | | alpha/beta hydrolase | cofit | 24 | 84 |
| | Variovorax sp. OAS795 | ABID97_RS21715 | | alpha/beta hydrolase | insig. | 28 | 85 |
| | Pseudomonas segetis P6 | MPMX49_02421 | | Haloalkane dehalogenase | insig. | 26 | 83 |
| o | Pseudomonas stutzeri RCH2 | Psest_3914 | | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) | insig. | 25 | 94 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4689 | | hydrolase, alpha/beta fold family | insig. | 30 | 42 |
| | Lysobacter sp. OAE881 | ABIE51_RS10335 | | alpha/beta hydrolase | insig. | 26 | 85 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS16425 | | alpha/beta hydrolase | insig. | 24 | 85 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS11780 | | alpha/beta hydrolase | insig. | 39 | 35 |
| | Pseudomonas sp. SVBP6 | COO64_RS21960 | | alpha/beta fold hydrolase | insig. | 26 | 94 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1080 | | hydrolase, alpha/beta fold family | insig. | 32 | 42 |
| o | Pseudomonas sp. RS175 | PFR28_00214 | | Cis-3-alkyl-4-alkyloxetan-2-one decarboxylase | insig. | 27 | 84 |
| | Mycobacterium tuberculosis H37Rv | Rv0134 | | Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) | insig. | 27 | 91 |
| | Xanthobacter sp. DMC5 | GFF2755 | | Soluble epoxide hydrolase | insig. | 34 | 40 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08960 | | haloalkane dehalogenase | insig. | 32 | 50 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4970 | | Alpha/beta hydrolase fold (EC 3.8.1.5) | insig. | 27 | 83 |
| o | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS04870 | | hydrolase | insig. | 26 | 90 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_1032 | | Alpha/beta hydrolase fold (EC 3.8.1.5) | insig. | 24 | 91 |
| o | Dickeya dadantii 3937 | DDA3937_RS08295 | | alpha/beta hydrolase | insig. | 24 | 83 |
| | Pseudomonas sp. DMC3 | GFF2349 | | 3-oxoadipate enol-lactonase 2 | cofit | 31 | 61 |
| | Enterobacter sp. TBS_079 | MPMX20_00037 | | Putative aminoacrylate hydrolase RutD | insig. | 34 | 44 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4508 | | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) | insig. | 32 | 42 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2971 | | Epoxide hydrolase | insig. | 25 | 85 |
| | Pseudomonas segetis P6 | MPMX49_03699 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 25 | 92 |
| o | Pseudomonas syringae pv. syringae B728a | Psyr_3187 | | Alpha/beta hydrolase fold protein | insig. | 24 | 90 |
| o | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3187 | | Alpha/beta hydrolase fold protein | insig. | 24 | 90 |
| o | Bosea sp. OAE506 | ABIE41_RS18955 | | alpha/beta hydrolase | insig. | 24 | 84 |
| | Pseudomonas segetis P6 | MPMX49_03672 | | Haloalkane dehalogenase | insig. | 29 | 42 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_26035 | | alpha/beta hydrolase | insig. | 32 | 42 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3345 | | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) | insig. | 24 | 88 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_04240 | | 3-oxoadipate enol-lactonase | insig. | 37 | 41 |
| | Pseudomonas sp. DMC3 | GFF1868 | | Cis-3-alkyl-4-alkyloxetan-2-one decarboxylase | insig. | 26 | 92 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4966 | | putative hydrolase | insig. | 25 | 90 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS22510 | | alpha/beta hydrolase | insig. | 24 | 86 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS19615 | | alpha/beta hydrolase | insig. | 27 | 86 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3101 | | Alpha/beta hydrolase fold protein | insig. | 32 | 40 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3101 | | Alpha/beta hydrolase fold protein | insig. | 32 | 40 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS14495 | | alpha/beta hydrolase | insig. | 25 | 84 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS14495 | | alpha/beta hydrolase | insig. | 25 | 84 |
| o | Alteromonas macleodii MIT1002 | MIT1002_01749 | | Haloalkane dehalogenase | insig. | 23 | 84 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS23420 | | alpha/beta hydrolase | insig. | 26 | 78 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS04455 | | alpha/beta hydrolase | insig. | 25 | 84 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS00330 | | alpha/beta hydrolase | insig. | 34 | 44 |
| | Ralstonia solanacearum UW163 | UW163_RS13660 | | alpha/beta hydrolase | insig. | 34 | 44 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_15530 | | alpha/beta hydrolase | insig. | 32 | 38 |
| | Pseudomonas sp. RS175 | PFR28_02143 | | Haloalkane dehalogenase | insig. | 31 | 42 |