Conservation of cofitness between Psyr_4573 and Psyr_1257 in Pseudomonas syringae pv. syringae B728a

74 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas syringae pv. syringae B728a 1.0 Psyr_4573 Histidine triad (HIT) protein 1.0 Psyr_1257 2-isopropylmalate synthase 0.54 14
Pseudomonas syringae pv. syringae B728a ΔmexB 1.00 Psyr_4573 Histidine triad (HIT) protein 1.00 Psyr_1257 2-isopropylmalate synthase low > 86
Pseudomonas sp. RS175 0.99 PFR28_04038 Purine nucleoside phosphoramidase 0.92 PFR28_00305 2-isopropylmalate synthase low > 88
Pseudomonas fluorescens FW300-N2E2 0.98 Pf6N2E2_4831 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) 0.92 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) low > 103
Pseudomonas fluorescens FW300-N2C3 0.97 AO356_14465 zinc-binding protein 0.92 AO356_06550 2-isopropylmalate synthase low > 104
Pseudomonas fluorescens FW300-N2E3 0.97 AO353_07180 zinc-binding protein 0.90 AO353_15925 2-isopropylmalate synthase 0.26 56
Pseudomonas fluorescens FW300-N1B4 0.97 Pf1N1B4_2554 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) 0.90 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) 0.22 40
Pseudomonas fluorescens SBW25 0.94 PFLU_RS27340 histidine triad nucleotide-binding protein 0.90 PFLU_RS24765 2-isopropylmalate synthase low > 109
Pseudomonas fluorescens GW456-L13 0.94 PfGW456L13_1228 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) 0.90 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) low > 87
Pseudomonas fluorescens SBW25-INTG 0.94 PFLU_RS27340 histidine triad nucleotide-binding protein 0.90 PFLU_RS24765 2-isopropylmalate synthase low > 109
Pseudomonas putida KT2440 0.88 PP_0428 aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase 0.91 PP_1025 2-isopropylmalate synthase 0.18 24
Pseudomonas simiae WCS417 0.88 PS417_25685 zinc-binding protein 0.90 PS417_23110 2-isopropylmalate synthase low > 88
Pseudomonas stutzeri RCH2 0.78 Psest_3643 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 0.83 Psest_1277 2-isopropylmalate synthase, yeast type low > 67
Pseudomonas sp. S08-1 0.78 OH686_15165 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) 0.78 OH686_17570 2-isopropylmalate synthase low > 80
Marinobacter adhaerens HP15 0.65 HP15_3384 HIT (histidine triad) family protein 0.52 HP15_2055 2-isopropylmalate synthase low > 73
Alteromonas macleodii MIT1002 0.64 MIT1002_00744 HIT-like protein 0.10 MIT1002_00949 2-isopropylmalate synthase low > 70
Synechococcus elongatus PCC 7942 0.61 Synpcc7942_1390 protein kinase C inhibitor 0.09 Synpcc7942_1410 leuA 2-isopropylmalate synthase — —
Rhodanobacter sp. FW510-T8 0.58 OKGIIK_05660 hinT histidine triad nucleotide-binding protein 0.09 OKGIIK_13575 leuA 2-isopropylmalate synthase low > 52
Dyella japonica UNC79MFTsu3.2 0.56 ABZR86_RS06230 histidine triad nucleotide-binding protein 0.09 ABZR86_RS15970 2-isopropylmalate synthase low > 74
Rhodanobacter denitrificans FW104-10B01 0.55 LRK54_RS01245 histidine triad nucleotide-binding protein 0.09 LRK54_RS10345 2-isopropylmalate synthase low > 59
Rhodanobacter denitrificans MT42 0.54 LRK55_RS01015 histidine triad nucleotide-binding protein 0.09 LRK55_RS09985 2-isopropylmalate synthase low > 63
Lysobacter sp. OAE881 0.51 ABIE51_RS14005 histidine triad nucleotide-binding protein 0.10 ABIE51_RS17570 2-isopropylmalate synthase low > 62
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_09495 histidine triad nucleotide-binding protein 0.10 CSW01_12595 2-isopropylmalate synthase low > 62
Serratia liquefaciens MT49 0.49 IAI46_09880 purine nucleoside phosphoramidase 0.58 IAI46_09630 2-isopropylmalate synthase low > 86
Shewanella loihica PV-4 0.49 Shew_1731 histidine triad (HIT) protein (RefSeq) 0.09 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.31 22
Shewanella sp. ANA-3 0.49 Shewana3_2507 histidine triad (HIT) protein (RefSeq) 0.10 Shewana3_3761 2-isopropylmalate synthase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.49 SO2723 HIT family protein (NCBI ptt file) 0.10 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) — —
Shewanella amazonensis SB2B 0.49 Sama_1448 HIT family protein (RefSeq) 0.10 Sama_0335 2-isopropylmalate synthase (RefSeq) low > 62
Klebsiella michiganensis M5al 0.48 BWI76_RS11145 histidine triad nucleotide-binding protein 0.55 BWI76_RS22105 2-isopropylmalate synthase — —
Pectobacterium carotovorum WPP14 0.48 HER17_RS08705 purine nucleoside phosphoramidase 0.09 HER17_RS03085 2-isopropylmalate synthase low > 75
Dickeya dianthicola ME23 0.47 DZA65_RS13605 purine nucleoside phosphoramidase 0.11 DZA65_RS19200 2-isopropylmalate synthase low > 75
Variovorax sp. OAS795 0.47 ABID97_RS23085 histidine triad nucleotide-binding protein 0.60 ABID97_RS14905 2-isopropylmalate synthase low > 91
Rahnella sp. WP5 0.47 EX31_RS24480 purine nucleoside phosphoramidase 0.58 EX31_RS24130 2-isopropylmalate synthase low > 89
Dickeya dadantii 3937 0.47 DDA3937_RS13070 purine nucleoside phosphoramidase 0.51 DDA3937_RS02895 2-isopropylmalate synthase low > 74
Dickeya dianthicola 67-19 0.47 HGI48_RS13135 purine nucleoside phosphoramidase 0.10 HGI48_RS18055 2-isopropylmalate synthase low > 71
Variovorax sp. SCN45 0.47 GFF5361 FIG146285: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 0.60 GFF1164 2-isopropylmalate synthase (EC 2.3.3.13) low > 127
Pantoea sp. MT58 0.46 IAI47_12015 purine nucleoside phosphoramidase 0.52 IAI47_10235 2-isopropylmalate synthase low > 76
Enterobacter asburiae PDN3 0.46 EX28DRAFT_1827 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 0.57 EX28DRAFT_2770 2-isopropylmalate synthase, yeast type low > 76
Acidovorax sp. GW101-3H11 0.46 Ac3H11_4739 FIG146285: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 0.55 Ac3H11_5000 2-isopropylmalate synthase (EC 2.3.3.13) low > 79
Escherichia coli ECOR27 0.45 NOLOHH_21055 hinT purine nucleoside phosphoramidase 0.09 NOLOHH_03060 2-isopropylmalate synthase low > 75
Escherichia coli ECRC102 0.45 NIAGMN_24305 hinT purine nucleoside phosphoramidase 0.09 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli BL21 0.45 ECD_01099 purine nucleoside phosphoramidase, dadA activator protein 0.09 ECD_00076 2-isopropylmalate synthase — —
Escherichia coli BW25113 0.45 b1103 ycfF orf, hypothetical protein (VIMSS) 0.09 b0074 leuA 2-isopropylmalate synthase (NCBI) low > 76
Escherichia fergusonii Becca 0.45 EFB2_02872 Purine nucleoside phosphoramidase 0.09 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli ECOR38 0.45 HEPCGN_23960 hinT purine nucleoside phosphoramidase 0.09 HEPCGN_08695 2-isopropylmalate synthase low > 87
Escherichia coli ECRC101 0.45 MCAODC_22885 hinT purine nucleoside phosphoramidase 0.09 MCAODC_01230 2-isopropylmalate synthase low > 87
Escherichia coli ECRC62 0.45 BNILDI_19215 hinT purine nucleoside phosphoramidase 0.09 BNILDI_08550 2-isopropylmalate synthase low > 75
Escherichia coli ECRC98 0.45 JDDGAC_07185 hinT purine nucleoside phosphoramidase 0.09 JDDGAC_14310 2-isopropylmalate synthase — —
Escherichia coli ECRC99 0.45 KEDOAH_24230 hinT purine nucleoside phosphoramidase 0.09 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli ECRC100 0.45 OKFHMN_03525 hinT purine nucleoside phosphoramidase 0.09 OKFHMN_10715 2-isopropylmalate synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.45 OHPLBJKB_02563 Purine nucleoside phosphoramidase 0.09 OHPLBJKB_03583 2-isopropylmalate synthase — —
Cupriavidus basilensis FW507-4G11 0.45 RR42_RS18865 hydrolase 0.62 RR42_RS21205 2-isopropylmalate synthase low > 128
Enterobacter sp. TBS_079 0.45 MPMX20_01784 Purine nucleoside phosphoramidase 0.55 MPMX20_03565 2-isopropylmalate synthase low > 85
Escherichia coli Nissle 1917 0.44 ECOLIN_RS06370 purine nucleoside phosphoramidase 0.09 ECOLIN_RS00400 2-isopropylmalate synthase — —
Xanthomonas campestris pv. campestris strain 8004 0.44 Xcc-8004.4011.1 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) 0.09 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) low > 74
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS20300 HIT family hydrolase 0.66 HSERO_RS17185 2-isopropylmalate synthase — —
Erwinia tracheiphila SCR3 0.44 LU632_RS14775 hinT purine nucleoside phosphoramidase 0.10 LU632_RS02880 leuA 2-isopropylmalate synthase low > 74
Hydrogenophaga sp. GW460-11-11-14-LB1 0.44 GFF1304 FIG146285: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 0.62 GFF4280 2-isopropylmalate synthase (EC 2.3.3.13) low > 90
Dechlorosoma suillum PS 0.43 Dsui_1421 HIT family hydrolase, diadenosine tetraphosphate hydrolase 0.60 Dsui_3227 2-isopropylmalate synthase low > 51
Paraburkholderia sabiae LMG 24235 0.42 QEN71_RS27815 histidine triad nucleotide-binding protein 0.58 QEN71_RS01640 2-isopropylmalate synthase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.42 H281DRAFT_05663 histidine triad (HIT) family protein 0.63 H281DRAFT_00385 2-isopropylmalate synthase low > 103
Paraburkholderia graminis OAS925 0.41 ABIE53_003691 histidine triad (HIT) family protein 0.63 ABIE53_002867 2-isopropylmalate synthase low > 113
Castellaniella sp019104865 MT123 0.41 ABCV34_RS11265 histidine triad nucleotide-binding protein 0.61 ABCV34_RS12420 2-isopropylmalate synthase — —
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS17660 HIT family hydrolase 0.64 BPHYT_RS13280 2-isopropylmalate synthase low > 109
Rhodospirillum rubrum S1H 0.39 Rru_A3592 Histidine triad (HIT) protein (NCBI) 0.57 Rru_A1928 Yeast 2-isopropylmalate synthase (NCBI) — —
Magnetospirillum magneticum AMB-1 0.36 AMB_RS22915 histidine triad nucleotide-binding protein 0.56 AMB_RS17550 2-isopropylmalate synthase low > 64
Dinoroseobacter shibae DFL-12 0.35 Dshi_0679 histidine triad (HIT) protein (RefSeq) 0.10 Dshi_0596 2-isopropylmalate synthase (RefSeq) low > 64
Bifidobacterium breve UCC2003 0.35 BBR_RS15155 histidine triad nucleotide-binding protein 0.48 BBR_RS11170 2-isopropylmalate synthase low > 34
Azospirillum brasilense Sp245 0.33 AZOBR_RS01695 hypothetical protein 0.57 AZOBR_RS12155 2-isopropylmalate synthase low > 97
Sphingomonas koreensis DSMZ 15582 0.33 Ga0059261_1052 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 0.59 Ga0059261_4031 2-isopropylmalate synthase, yeast type low > 68
Azospirillum sp. SherDot2 0.32 MPMX19_02540 Purine nucleoside phosphoramidase 0.57 MPMX19_01822 2-isopropylmalate synthase low > 112
Phaeobacter inhibens DSM 17395 0.31 PGA1_c06720 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 0.10 PGA1_c26470 2-isopropylmalate synthase LeuA low > 62
Desulfovibrio vulgaris Miyazaki F 0.29 DvMF_1561 histidine triad (HIT) protein (RefSeq) 0.13 DvMF_1791 2-isopropylmalate synthase (RefSeq) low > 51
Methanococcus maripaludis S2 0.29 MMP_RS01765 HIT family protein 0.09 MMP_RS05500 2-isopropylmalate synthase low > 25
Methanococcus maripaludis JJ 0.29 MMJJ_RS03610 HIT family protein 0.09 MMJJ_RS08870 2-isopropylmalate synthase low > 28

Not shown: 3 genomes with orthologs for Psyr_4573 only; 21 genomes with orthologs for Psyr_1257 only