Conservation of cofitness between HER17_RS02600 and HER17_RS17435 in Pectobacterium carotovorum WPP14

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS02600 protease modulator HflC 1.0 HER17_RS17435 type II toxin-antitoxin system RatA family toxin 0.81 9
Dickeya dianthicola 67-19 0.82 HGI48_RS18530 protease modulator HflC 0.80 HGI48_RS04305 type II toxin-antitoxin system RatA family toxin low > 71
Dickeya dianthicola ME23 0.82 DZA65_RS19665 protease modulator HflC 0.80 DZA65_RS04220 type II toxin-antitoxin system RatA family toxin low > 75
Dickeya dadantii 3937 0.82 DDA3937_RS18595 protease modulator HflC 0.82 DDA3937_RS04310 type II toxin-antitoxin system RatA family toxin — —
Serratia liquefaciens MT49 0.81 IAI46_01640 protease modulator HflC 0.83 IAI46_19650 type II toxin-antitoxin system RatA family toxin — —
Erwinia tracheiphila SCR3 0.79 LU632_RS02070 hflC protease modulator HflC 0.74 LU632_RS17020 type II toxin-antitoxin system RatA family toxin low > 74
Pantoea sp. MT58 0.77 IAI47_02605 protease modulator HflC 0.75 IAI47_04795 type II toxin-antitoxin system RatA family toxin — —
Rahnella sp. WP5 0.77 EX31_RS08805 protease modulator HflC 0.76 EX31_RS21745 type II toxin-antitoxin system RatA family toxin — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.77 GFF828 HflC protein 0.66 GFF4159 Putative oligoketide cyclase/lipid transport protein, similarity with yeast ubiquinone-binding protein YOL008W — —
Escherichia fergusonii Becca 0.77 EFB2_04360 Modulator of FtsH protease HflC 0.79 EFB2_01274 Persistence and stress-resistance toxin PasT low > 86
Escherichia coli ECRC62 0.77 BNILDI_06985 hflC protease modulator HflC 0.78 BNILDI_11605 ratA type II toxin-antitoxin system toxin RatA — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.77 OHPLBJKB_03867 Modulator of FtsH protease HflC 0.78 OHPLBJKB_01088 Ribosome association toxin RatA — —
Escherichia coli Nissle 1917 0.77 ECOLIN_RS24245 protease modulator HflC 0.78 ECOLIN_RS14790 type II toxin-antitoxin system toxin RatA — —
Escherichia coli ECOR38 0.77 HEPCGN_10470 hflC protease modulator HflC 0.78 HEPCGN_20250 ratA type II toxin-antitoxin system toxin RatA low > 87
Escherichia coli ECRC101 0.77 MCAODC_02755 hflC protease modulator HflC 0.78 MCAODC_11655 ratA type II toxin-antitoxin system toxin RatA — —
Escherichia coli ECRC99 0.77 KEDOAH_15915 hflC protease modulator HflC 0.78 KEDOAH_07090 ratA type II toxin-antitoxin system toxin RatA — —
Escherichia coli BW25113 0.77 b4175 hflC modulator for HflB protease specific for phage lambda cII repressor (NCBI) 0.78 b2619 yfjG hypothetical protein (NCBI) — —
Escherichia coli BL21 0.77 ECD_04042 HflB protease modulator specific for phage lambda cII repressor 0.78 ECD_02507 toxic UPF0083 family protein inhibitor of 70S ribosome formation low > 61
Escherichia coli ECOR27 0.77 NOLOHH_04505 hflC protease modulator HflC 0.78 NOLOHH_12800 ratA type II toxin-antitoxin system toxin RatA — —
Escherichia coli ECRC98 0.77 JDDGAC_15880 hflC protease modulator HflC 0.78 JDDGAC_24795 ratA type II toxin-antitoxin system toxin RatA — —
Escherichia coli ECRC100 0.77 OKFHMN_12240 hflC protease modulator HflC 0.78 OKFHMN_21130 ratA type II toxin-antitoxin system toxin RatA — —
Escherichia coli ECRC102 0.77 NIAGMN_10090 hflC protease modulator HflC 0.78 NIAGMN_18900 ratA type II toxin-antitoxin system toxin RatA — —
Klebsiella michiganensis M5al 0.75 BWI76_RS02550 protease modulator HflC 0.75 BWI76_RS21575 hypothetical protein — —
Enterobacter sp. TBS_079 0.74 MPMX20_00456 Modulator of FtsH protease HflC 0.77 MPMX20_03489 Persistence and stress-resistance toxin PasT — —
Enterobacter asburiae PDN3 0.73 EX28DRAFT_3372 HflC protein 0.77 EX28DRAFT_2722 Oligoketide cyclase/lipid transport protein — —
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_01850 protease modulator HflC 0.64 CSW01_04380 ubiquinone-binding protein — —
Alteromonas macleodii MIT1002 0.48 MIT1002_03785 Modulator of FtsH protease HflC 0.58 MIT1002_01807 Toxin RatA — —
Shewanella sp. ANA-3 0.48 Shewana3_0600 HflC protein (RefSeq) 0.58 Shewana3_2951 cyclase/dehydrase (RefSeq) — —
Shewanella oneidensis MR-1 0.47 SO0606 hflC hflC protein (NCBI ptt file) 0.57 SO1474 conserved hypothetical protein (NCBI ptt file) — —
Shewanella loihica PV-4 0.46 Shew_0569 HflC protein (RefSeq) 0.59 Shew_1269 cyclase/dehydrase (RefSeq) — —
Shewanella amazonensis SB2B 0.45 Sama_3022 hflC protein (RefSeq) 0.60 Sama_2387 hypothetical protein (RefSeq) — —
Kangiella aquimarina DSM 16071 0.34 B158DRAFT_1955 HflC protein 0.49 B158DRAFT_0970 Oligoketide cyclase/lipid transport protein — —
Dechlorosoma suillum PS 0.33 Dsui_3134 membrane protease subunit, stomatin/prohibitin 0.38 Dsui_2674 oligoketide cyclase/lipid transport protein — —
Pseudomonas fluorescens FW300-N1B4 0.31 Pf1N1B4_1409 HflC protein 0.45 Pf1N1B4_1182 Putative oligoketide cyclase/dehydratase or lipid transport protein YfjG — —
Marinobacter adhaerens HP15 0.31 HP15_2496 HflC 0.46 HP15_3088 oligoketide cyclase/lipid transport protein low > 73
Pseudomonas fluorescens FW300-N2C3 0.31 AO356_08640 membrane protease HflC 0.48 AO356_07530 ribosome association toxin RatA — —
Pseudomonas fluorescens FW300-N2E2 0.31 Pf6N2E2_3611 HflC protein 0.47 Pf6N2E2_3375 Putative oligoketide cyclase/lipid transport protein, similarity with yeast ubiquinone-binding protein YOL008W — —
Pseudomonas syringae pv. syringae B728a 0.31 Psyr_0575 protease FtsH subunit HflC 0.45 Psyr_4201 cyclase/dehydrase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.31 Psyr_0575 protease FtsH subunit HflC 0.45 Psyr_4201 cyclase/dehydrase — —
Pseudomonas fluorescens SBW25 0.31 PFLU_RS02585 protease modulator HflC 0.43 PFLU_RS25930 type II toxin-antitoxin system RatA family toxin — —
Pseudomonas fluorescens SBW25-INTG 0.31 PFLU_RS02585 protease modulator HflC 0.43 PFLU_RS25930 type II toxin-antitoxin system RatA family toxin — —
Pseudomonas fluorescens GW456-L13 0.31 PfGW456L13_151 HflC protein 0.46 PfGW456L13_5110 Putative oligoketide cyclase/lipid transport protein, similarity with yeast ubiquinone-binding protein YOL008W — —
Pseudomonas fluorescens FW300-N2E3 0.31 AO353_13160 membrane protease HflC 0.44 AO353_05680 ribosome association toxin RatA — —
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_06645 hflC protease modulator HflC 0.35 OKGIIK_07370 pasT ubiquinone-binding protein — —
Pseudomonas stutzeri RCH2 0.29 Psest_0686 Membrane protease subunits, stomatin/prohibitin homologs 0.45 Psest_0958 Oligoketide cyclase/lipid transport protein — —
Pseudomonas sp. S08-1 0.29 OH686_09455 HflC protein 0.45 OH686_17030 Ribosome association toxin RatA — —
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS08350 protease modulator HflC 0.39 ABZR86_RS05695 type II toxin-antitoxin system RatA family toxin — —
Azospirillum sp. SherDot2 0.29 MPMX19_01250 Modulator of FtsH protease HflC 0.31 MPMX19_01105 Persistence and stress-resistance toxin PasT — —
Pseudomonas simiae WCS417 0.29 PS417_02505 membane protease HflC 0.44 PS417_24090 ribosome association toxin RatA — —
Ralstonia solanacearum IBSBF1503 0.29 RALBFv3_RS15315 protease modulator HflC 0.43 RALBFv3_RS00495 ubiquinone-binding protein — —
Ralstonia solanacearum PSI07 0.29 RPSI07_RS18060 protease modulator HflC 0.43 RPSI07_RS16995 ubiquinone-binding protein — —
Ralstonia solanacearum UW163 0.29 UW163_RS12780 protease modulator HflC 0.43 UW163_RS13825 ubiquinone-binding protein — —
Xanthomonas campestris pv. campestris strain 8004 0.28 Xcc-8004.3954.1 HflC protein 0.34 Xcc-8004.3436.1 hypothetical protein — —
Cupriavidus basilensis FW507-4G11 0.28 RR42_RS13100 membrane protein 0.42 RR42_RS11770 cyclase — —
Rhodopseudomonas palustris CGA009 0.28 TX73_018075 protease modulator HflC 0.26 TX73_013395 type II toxin-antitoxin system RatA family toxin — —
Pseudomonas sp. RS175 0.28 PFR28_05124 Modulator of FtsH protease HflC 0.47 PFR28_00067 Ribosome association toxin RatA — —
Rhodanobacter denitrificans MT42 0.28 LRK55_RS00385 protease modulator HflC 0.37 LRK55_RS17785 type II toxin-antitoxin system RatA family toxin — —
Ralstonia solanacearum GMI1000 0.28 RS_RS06125 protease modulator HflC 0.43 RS_RS07150 ubiquinone-binding protein — —
Rhodanobacter denitrificans FW104-10B01 0.28 LRK54_RS00615 protease modulator HflC 0.37 LRK54_RS17930 type II toxin-antitoxin system RatA family toxin — —
Phaeobacter inhibens DSM 17395 0.28 PGA1_c23700 protein HflC 0.33 PGA1_c14720 Oligoketide cyclase/lipid transport protein low > 62
Lysobacter sp. OAE881 0.28 ABIE51_RS06555 protease modulator HflC 0.35 ABIE51_RS11675 type II toxin-antitoxin system RatA family toxin low > 62
Ralstonia sp. UNC404CL21Col 0.27 ABZR87_RS10955 protease modulator HflC 0.44 ABZR87_RS11945 type II toxin-antitoxin system RatA family toxin — —
Herbaspirillum seropedicae SmR1 0.27 HSERO_RS14760 membrane protein 0.41 HSERO_RS11005 cyclase — —
Rhodospirillum rubrum S1H 0.27 Rru_A2202 HflC (NCBI) 0.30 Rru_A1876 cyclase/dehydrase (NCBI) — —
Castellaniella sp019104865 MT123 0.27 ABCV34_RS02665 protease modulator HflC 0.44 ABCV34_RS04005 type II toxin-antitoxin system RatA family toxin — —
Magnetospirillum magneticum AMB-1 0.27 AMB_RS17655 protease modulator HflC 0.32 AMB_RS11740 ubiquinone-binding protein — —
Azospirillum brasilense Sp245 0.27 AZOBR_RS06525 membrane protein 0.34 AZOBR_RS14400 cyclase — —
Bosea sp. OAE506 0.27 ABIE41_RS12855 protease modulator HflC 0.27 ABIE41_RS16810 type II toxin-antitoxin system RatA family toxin low > 77
Dinoroseobacter shibae DFL-12 0.27 Dshi_2735 HflC protein (RefSeq) 0.35 Dshi_1580 cyclase/dehydrase (RefSeq) low > 64
Agrobacterium fabrum C58 0.26 Atu2044 HFLC protein 0.27 Atu1441 hypothetical protein — —
Acidovorax sp. GW101-3H11 0.25 Ac3H11_1802 HflC protein 0.42 Ac3H11_2860 Putative oligoketide cyclase/lipid transport protein, similarity with yeast ubiquinone-binding protein YOL008W low > 79
Variovorax sp. OAS795 0.24 ABID97_RS14265 protease modulator HflC 0.44 ABID97_RS16430 type II toxin-antitoxin system RatA family toxin low > 91
Paraburkholderia graminis OAS925 0.23 ABIE53_002734 membrane protease subunit HflC 0.45 ABIE53_002481 ribosome-associated toxin RatA of RatAB toxin-antitoxin module — —
Variovorax sp. SCN45 0.23 GFF1003 HflC protein 0.45 GFF212 Ribosome association toxin RatA low > 127
Sinorhizobium meliloti 1021 0.23 SMc01440 hydrolase serine protease transmembrane protein 0.26 SMc01038 hypothetical protein — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.21 GFF4855 HflC protein 0.40 GFF4353 Putative oligoketide cyclase/lipid transport protein, similarity with yeast ubiquinone-binding protein YOL008W low > 90
Paraburkholderia bryophila 376MFSha3.1 0.21 H281DRAFT_00524 protease FtsH subunit HflC 0.45 H281DRAFT_00631 Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module — —
Paraburkholderia sabiae LMG 24235 0.21 QEN71_RS06015 protease modulator HflC 0.44 QEN71_RS06525 type II toxin-antitoxin system RatA family toxin — —
Rhizobium sp. OAE497 0.19 ABIE40_RS11530 protease modulator HflC 0.26 ABIE40_RS09060 type II toxin-antitoxin system RatA family toxin low > 107
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS12540 membrane protein 0.45 BPHYT_RS12035 cyclase — —
Sphingomonas koreensis DSMZ 15582 0.16 Ga0059261_1381 Membrane protease subunits, stomatin/prohibitin homologs 0.33 Ga0059261_0147 Oligoketide cyclase/lipid transport protein — —

Not shown: 4 genomes with orthologs for HER17_RS02600 only; 3 genomes with orthologs for HER17_RS17435 only