| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Pectobacterium carotovorum WPP14 | 1.0 | HER17_RS02600 | | protease modulator HflC | 1.0 | HER17_RS10755 | | class II fumarate hydratase | 0.79 | 16 |
| Dickeya dianthicola 67-19 | 0.82 | HGI48_RS18530 | | protease modulator HflC | 0.89 | HGI48_RS10655 | | class II fumarate hydratase | low | > 71 |
| Dickeya dianthicola ME23 | 0.82 | DZA65_RS19665 | | protease modulator HflC | 0.89 | DZA65_RS11125 | | class II fumarate hydratase | low | > 75 |
| Dickeya dadantii 3937 | 0.82 | DDA3937_RS18595 | | protease modulator HflC | 0.89 | DDA3937_RS10655 | | class II fumarate hydratase | — | — |
| Serratia liquefaciens MT49 | 0.81 | IAI46_01640 | | protease modulator HflC | 0.88 | IAI46_11655 | | class II fumarate hydratase | low | > 86 |
| Erwinia tracheiphila SCR3 | 0.79 | LU632_RS02070 | hflC | protease modulator HflC | 0.84 | LU632_RS12335 | fumC | class II fumarate hydratase | low | > 74 |
| Pantoea sp. MT58 | 0.77 | IAI47_02605 | | protease modulator HflC | 0.86 | IAI47_10335 | | class II fumarate hydratase | low | > 76 |
| Rahnella sp. WP5 | 0.77 | EX31_RS08805 | | protease modulator HflC | 0.87 | EX31_RS06965 | | class II fumarate hydratase | low | > 89 |
| Escherichia fergusonii Becca | 0.77 | EFB2_04360 | | Modulator of FtsH protease HflC | 0.83 | EFB2_02381 | | Fumarate hydratase class II | low | > 86 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.77 | GFF828 | | HflC protein | 0.84 | GFF1806 | | Fumarate hydratase class II (EC 4.2.1.2) | low | > 78 |
| Escherichia coli ECRC99 | 0.77 | KEDOAH_15915 | hflC | protease modulator HflC | 0.83 | KEDOAH_00455 | fumC | class II fumarate hydratase | — | — |
| Escherichia coli BL21 | 0.77 | ECD_04042 | | HflB protease modulator specific for phage lambda cII repressor | 0.82 | ECD_01580 | | fumarate hydratase (fumarase C),aerobic Class II | — | — |
| Escherichia coli ECOR27 | 0.77 | NOLOHH_04505 | hflC | protease modulator HflC | 0.83 | NOLOHH_18155 | fumC | class II fumarate hydratase | low | > 75 |
| Escherichia coli ECRC102 | 0.77 | NIAGMN_10090 | hflC | protease modulator HflC | 0.83 | NIAGMN_00425 | fumC | class II fumarate hydratase | — | — |
| Escherichia coli ECRC62 | 0.77 | BNILDI_06985 | hflC | protease modulator HflC | 0.83 | BNILDI_16945 | fumC | class II fumarate hydratase | low | > 75 |
| Escherichia coli BW25113 | 0.77 | b4175 | hflC | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | 0.82 | b1611 | fumC | fumarate hydratase (NCBI) | low | > 76 |
| Escherichia coli Nissle 1917 | 0.77 | ECOLIN_RS24245 | | protease modulator HflC | 0.83 | ECOLIN_RS08995 | | class II fumarate hydratase | — | — |
| Escherichia coli ECOR38 | 0.77 | HEPCGN_10470 | hflC | protease modulator HflC | 0.82 | HEPCGN_06025 | fumC | class II fumarate hydratase | low | > 87 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.77 | OHPLBJKB_03867 | | Modulator of FtsH protease HflC | 0.84 | OHPLBJKB_02115 | | Fumarate hydratase class II | low | > 73 |
| Escherichia coli ECRC101 | 0.77 | MCAODC_02755 | hflC | protease modulator HflC | 0.83 | MCAODC_17760 | fumC | class II fumarate hydratase | low | > 87 |
| Escherichia coli ECRC100 | 0.77 | OKFHMN_12240 | hflC | protease modulator HflC | 0.83 | OKFHMN_27650 | fumC | class II fumarate hydratase | low | > 80 |
| Escherichia coli ECRC98 | 0.77 | JDDGAC_15880 | hflC | protease modulator HflC | 0.83 | JDDGAC_02240 | fumC | class II fumarate hydratase | low | > 86 |
| Klebsiella michiganensis M5al | 0.75 | BWI76_RS02550 | | protease modulator HflC | 0.85 | BWI76_RS16270 | | fumarate hydratase, class II | low | > 92 |
| Enterobacter sp. TBS_079 | 0.74 | MPMX20_00456 | | Modulator of FtsH protease HflC | 0.86 | MPMX20_02022 | | Fumarate hydratase class II | low | > 85 |
| Enterobacter asburiae PDN3 | 0.73 | EX28DRAFT_3372 | | HflC protein | 0.86 | EX28DRAFT_1608 | | fumarase, class II (EC 4.2.1.2) | low | > 76 |
| Vibrio cholerae E7946 ATCC 55056 | 0.49 | CSW01_01850 | | protease modulator HflC | 0.41 | CSW01_07895 | | class II fumarate hydratase | low | > 62 |
| Alteromonas macleodii MIT1002 | 0.48 | MIT1002_03785 | | Modulator of FtsH protease HflC | 0.40 | MIT1002_03167 | | Fumarate hydratase class II | low | > 70 |
| Shewanella loihica PV-4 | 0.46 | Shew_0569 | | HflC protein (RefSeq) | 0.37 | Shew_0068 | | fumarate lyase (RefSeq) | low | > 60 |
| Shewanella amazonensis SB2B | 0.45 | Sama_3022 | | hflC protein (RefSeq) | 0.39 | Sama_0822 | | fumarate hydratase (RefSeq) | low | > 62 |
| Kangiella aquimarina DSM 16071 | 0.34 | B158DRAFT_1955 | | HflC protein | 0.38 | B158DRAFT_1200 | | fumarase, class II (EC 4.2.1.2) | low | > 40 |
| Dechlorosoma suillum PS | 0.33 | Dsui_3134 | | membrane protease subunit, stomatin/prohibitin | 0.64 | Dsui_0926 | | fumarate hydratase, class II | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.31 | Pf1N1B4_1409 | | HflC protein | 0.55 | Pf1N1B4_367 | | Fumarate hydratase class II (EC 4.2.1.2) | — | — |
| Marinobacter adhaerens HP15 | 0.31 | HP15_2496 | | HflC | 0.39 | HP15_3132 | | fumarate hydratase class II | low | > 73 |
| Pseudomonas fluorescens FW300-N2E2 | 0.31 | Pf6N2E2_3611 | | HflC protein | 0.55 | Pf6N2E2_2536 | | Fumarate hydratase class II (EC 4.2.1.2) | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.31 | AO356_08640 | | membrane protease HflC | 0.55 | AO356_03545 | | fumarate hydratase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.31 | Psyr_0575 | | protease FtsH subunit HflC | 0.57 | Psyr_3661 | | Fumarate hydratase, class II | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.31 | Psyr_0575 | | protease FtsH subunit HflC | 0.57 | Psyr_3661 | | Fumarate hydratase, class II | low | > 86 |
| Pseudomonas fluorescens GW456-L13 | 0.31 | PfGW456L13_151 | | HflC protein | 0.56 | PfGW456L13_2160 | | Fumarate hydratase class II (EC 4.2.1.2) | low | > 87 |
| Pseudomonas fluorescens SBW25 | 0.31 | PFLU_RS02585 | | protease modulator HflC | 0.56 | PFLU_RS21170 | | class II fumarate hydratase | low | > 109 |
| Pseudomonas fluorescens FW300-N2E3 | 0.31 | AO353_13160 | | membrane protease HflC | 0.57 | AO353_02150 | | fumarate hydratase | low | > 101 |
| Pseudomonas fluorescens SBW25-INTG | 0.31 | PFLU_RS02585 | | protease modulator HflC | 0.56 | PFLU_RS21170 | | class II fumarate hydratase | low | > 109 |
| Rhodanobacter sp. FW510-T8 | 0.30 | OKGIIK_06645 | hflC | protease modulator HflC | 0.41 | OKGIIK_06345 | aspA | aspartate ammonia-lyase | low | > 52 |
| Pseudomonas stutzeri RCH2 | 0.29 | Psest_0686 | | Membrane protease subunits, stomatin/prohibitin homologs | 0.54 | Psest_2682 | | fumarate hydratase, class II | — | — |
| Pseudomonas putida KT2440 | 0.29 | PP_4891 | | integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex | 0.55 | PP_1755 | | fumarate hydratase (class 2) | low | > 96 |
| Dyella japonica UNC79MFTsu3.2 | 0.29 | ABZR86_RS08350 | | protease modulator HflC | 0.42 | ABZR86_RS05855 | | class II fumarate hydratase | low | > 74 |
| Pseudomonas sp. S08-1 | 0.29 | OH686_09455 | | HflC protein | 0.54 | OH686_21015 | | fumarate hydratase, class II | low | > 80 |
| Azospirillum sp. SherDot2 | 0.29 | MPMX19_01250 | | Modulator of FtsH protease HflC | 0.59 | MPMX19_01424 | | Fumarate hydratase class II | — | — |
| Pseudomonas simiae WCS417 | 0.29 | PS417_02505 | | membane protease HflC | 0.57 | PS417_19200 | | fumarate hydratase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.29 | RALBFv3_RS15315 | | protease modulator HflC | 0.75 | RALBFv3_RS17680 | | class II fumarate hydratase | — | — |
| Ralstonia solanacearum PSI07 | 0.29 | RPSI07_RS18060 | | protease modulator HflC | 0.76 | RPSI07_RS05900 | | class II fumarate hydratase | low | > 81 |
| Ralstonia solanacearum UW163 | 0.29 | UW163_RS12780 | | protease modulator HflC | 0.75 | UW163_RS21470 | | class II fumarate hydratase | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.28 | Xcc-8004.3954.1 | | HflC protein | 0.42 | Xcc-8004.3403.1 | | Fumarate hydratase class II (EC 4.2.1.2) | low | > 74 |
| Cupriavidus basilensis FW507-4G11 | 0.28 | RR42_RS13100 | | membrane protein | 0.56 | RR42_RS33090 | | fumarate hydratase | — | — |
| Rhodopseudomonas palustris CGA009 | 0.28 | TX73_018075 | | protease modulator HflC | 0.57 | TX73_018130 | | class II fumarate hydratase | low | > 86 |
| Ralstonia solanacearum GMI1000 | 0.28 | RS_RS06125 | | protease modulator HflC | 0.76 | RS_RS23320 | | class II fumarate hydratase | — | — |
| Rhodanobacter denitrificans MT42 | 0.28 | LRK55_RS00385 | | protease modulator HflC | 0.41 | LRK55_RS00660 | | class II fumarate hydratase | low | > 63 |
| Pseudomonas sp. RS175 | 0.28 | PFR28_05124 | | Modulator of FtsH protease HflC | 0.55 | PFR28_00889 | | Fumarate hydratase class II | low | > 88 |
| Phaeobacter inhibens DSM 17395 | 0.28 | PGA1_c23700 | | protein HflC | 0.56 | PGA1_c13520 | | fumarate hydratase class II | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.28 | LRK54_RS00615 | | protease modulator HflC | 0.42 | LRK54_RS00885 | | class II fumarate hydratase | low | > 59 |
| Lysobacter sp. OAE881 | 0.28 | ABIE51_RS06555 | | protease modulator HflC | 0.41 | ABIE51_RS09015 | | class II fumarate hydratase | low | > 62 |
| Ralstonia sp. UNC404CL21Col | 0.27 | ABZR87_RS10955 | | protease modulator HflC | 0.75 | ABZR87_RS18630 | | class II fumarate hydratase | low | > 80 |
| Herbaspirillum seropedicae SmR1 | 0.27 | HSERO_RS14760 | | membrane protein | 0.68 | HSERO_RS07610 | | fumarate hydratase | low | > 78 |
| Rhodospirillum rubrum S1H | 0.27 | Rru_A2202 | | HflC (NCBI) | 0.54 | Rru_A2129 | | Fumarate hydratase, class II (NCBI) | — | — |
| Castellaniella sp019104865 MT123 | 0.27 | ABCV34_RS02665 | | protease modulator HflC | 0.58 | ABCV34_RS03655 | | class II fumarate hydratase | — | — |
| Magnetospirillum magneticum AMB-1 | 0.27 | AMB_RS17655 | | protease modulator HflC | 0.66 | AMB_RS18480 | | class II fumarate hydratase | — | — |
| Azospirillum brasilense Sp245 | 0.27 | AZOBR_RS06525 | | membrane protein | 0.58 | AZOBR_RS06120 | | fumarate hydratase | low | > 97 |
| Bosea sp. OAE506 | 0.27 | ABIE41_RS12855 | | protease modulator HflC | 0.53 | ABIE41_RS12805 | | class II fumarate hydratase | — | — |
| Dinoroseobacter shibae DFL-12 | 0.27 | Dshi_2735 | | HflC protein (RefSeq) | 0.54 | Dshi_2334 | | fumarate hydratase, class II (RefSeq) | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.26 | DvMF_2675 | | HflC protein (RefSeq) | 0.49 | DvMF_2075 | | fumarate hydratase, class II (RefSeq) | low | > 51 |
| Agrobacterium fabrum C58 | 0.26 | Atu2044 | | HFLC protein | 0.56 | Atu1616 | | fumarate hydratase | — | — |
| Acidovorax sp. GW101-3H11 | 0.25 | Ac3H11_1802 | | HflC protein | 0.73 | Ac3H11_943 | | Fumarate hydratase class II (EC 4.2.1.2) | low | > 79 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.25 | DVU0683 | | hflC protein, putative (TIGR) | 0.56 | DVU0080 | fumC | fumarate hydratase, class II (TIGR) | low | > 55 |
| Variovorax sp. OAS795 | 0.24 | ABID97_RS14265 | | protease modulator HflC | 0.72 | ABID97_RS17545 | | class II fumarate hydratase | low | > 91 |
| Variovorax sp. SCN45 | 0.23 | GFF1003 | | HflC protein | 0.72 | GFF479 | | Fumarate hydratase class II (EC 4.2.1.2) | low | > 127 |
| Paraburkholderia graminis OAS925 | 0.23 | ABIE53_002734 | | membrane protease subunit HflC | 0.72 | ABIE53_003084 | | fumarate hydratase class II | low | > 113 |
| Sinorhizobium meliloti 1021 | 0.23 | SMc01440 | | hydrolase serine protease transmembrane protein | 0.57 | SMc00149 | | fumarate hydratase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.21 | GFF4855 | | HflC protein | 0.72 | GFF4101 | | Fumarate hydratase class II (EC 4.2.1.2) | 0.58 | 79 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.21 | H281DRAFT_00524 | | protease FtsH subunit HflC | 0.72 | H281DRAFT_04314 | | fumarase, class II | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.21 | QEN71_RS06015 | | protease modulator HflC | 0.71 | QEN71_RS04360 | | class II fumarate hydratase | low | > 153 |
| Rhizobium sp. OAE497 | 0.19 | ABIE40_RS11530 | | protease modulator HflC | 0.57 | ABIE40_RS10540 | | class II fumarate hydratase | low | > 107 |
| Burkholderia phytofirmans PsJN | 0.19 | BPHYT_RS12540 | | membrane protein | 0.70 | BPHYT_RS14615 | | fumarate hydratase | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.19 | Echvi_2032 | | HflC protein | 0.59 | Echvi_1329 | | fumarate hydratase, class II | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.16 | Ga0059261_1381 | | Membrane protease subunits, stomatin/prohibitin homologs | 0.52 | Ga0059261_1040 | | fumarase, class II (EC 4.2.1.2) | low | > 68 |
Not shown: 2 genomes with orthologs for HER17_RS02600 only; 9 genomes with orthologs for HER17_RS10755 only