Conservation of cofitness between EX31_RS22280 and EX31_RS22120 in Rahnella sp. WP5

81 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Rahnella sp. WP5 1.0 EX31_RS22280 7-cyano-7-deazaguanine synthase QueC 1.0 EX31_RS22120 transcriptional regulator NrdR 0.54 15
Serratia liquefaciens MT49 0.88 IAI46_05045 7-cyano-7-deazaguanine synthase QueC 0.93 IAI46_04890 transcriptional regulator NrdR low > 86
Pantoea sp. MT58 0.83 IAI47_14620 7-cyano-7-deazaguanine synthase QueC 0.90 IAI47_14775 transcriptional regulator NrdR low > 76
Escherichia coli ECOR27 0.83 NOLOHH_01230 queC 7-cyano-7-deazaguanine synthase QueC 0.90 NOLOHH_01405 nrdR transcriptional regulator NrdR low > 75
Escherichia coli ECOR38 0.83 HEPCGN_06910 queC 7-cyano-7-deazaguanine synthase QueC 0.90 HEPCGN_07085 nrdR transcriptional regulator NrdR low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_03229 7-cyano-7-deazaguanine synthase 0.90 OHPLBJKB_03263 Transcriptional repressor NrdR low > 73
Escherichia coli Nissle 1917 0.83 ECOLIN_RS02660 7-cyano-7-deazaguanine synthase QueC 0.90 ECOLIN_RS02500 transcriptional regulator NrdR low > 55
Pectobacterium carotovorum WPP14 0.83 HER17_RS15815 7-cyano-7-deazaguanine synthase QueC 0.92 HER17_RS15965 transcriptional regulator NrdR low > 75
Escherichia fergusonii Becca 0.83 EFB2_03613 7-cyano-7-deazaguanine synthase 0.90 EFB2_03644 Transcriptional repressor NrdR low > 86
Escherichia coli BW25113 0.82 b0444 ybaX predicted aluminum resistance protein (NCBI) 0.90 b0413 ybaD hypothetical protein (NCBI) — —
Escherichia coli BL21 0.82 ECD_00396 7-cyano-7-deazaguanine (preQ0) synthase; queuosine biosynthesis 0.90 ECD_00361 Nrd regulon repressor low > 61
Dickeya dianthicola 67-19 0.82 HGI48_RS05715 7-cyano-7-deazaguanine synthase QueC 0.94 HGI48_RS05560 transcriptional regulator NrdR 0.49 56
Dickeya dianthicola ME23 0.82 DZA65_RS06040 7-cyano-7-deazaguanine synthase QueC 0.94 DZA65_RS05885 transcriptional regulator NrdR low > 75
Dickeya dadantii 3937 0.82 DDA3937_RS05670 7-cyano-7-deazaguanine synthase QueC 0.94 DDA3937_RS05500 transcriptional regulator NrdR low > 74
Escherichia coli ECRC62 0.82 BNILDI_22645 queC 7-cyano-7-deazaguanine synthase QueC 0.90 BNILDI_22820 nrdR transcriptional regulator NrdR — —
Escherichia coli ECRC98 0.82 JDDGAC_11950 queC 7-cyano-7-deazaguanine synthase QueC 0.90 JDDGAC_12115 nrdR transcriptional regulator NrdR low > 86
Escherichia coli ECRC99 0.82 KEDOAH_19670 queC 7-cyano-7-deazaguanine synthase QueC 0.90 KEDOAH_19505 nrdR transcriptional regulator NrdR — —
Escherichia coli ECRC100 0.82 OKFHMN_08295 queC 7-cyano-7-deazaguanine synthase QueC 0.90 OKFHMN_08460 nrdR transcriptional regulator NrdR low > 80
Escherichia coli ECRC101 0.82 MCAODC_27520 queC 7-cyano-7-deazaguanine synthase QueC 0.90 MCAODC_27685 nrdR transcriptional regulator NrdR low > 87
Escherichia coli ECRC102 0.82 NIAGMN_06350 queC 7-cyano-7-deazaguanine synthase QueC 0.90 NIAGMN_06515 nrdR transcriptional regulator NrdR — —
Klebsiella michiganensis M5al 0.82 BWI76_RS06560 7-cyano-7-deazaguanine synthase QueC 0.90 BWI76_RS06345 transcriptional regulator NrdR — —
Enterobacter sp. TBS_079 0.82 MPMX20_01035 7-cyano-7-deazaguanine synthase 0.89 MPMX20_01005 Transcriptional repressor NrdR low > 85
Enterobacter asburiae PDN3 0.81 EX28DRAFT_2526 queuosine biosynthesis protein QueC 0.89 EX28DRAFT_2557 transcriptional regulator NrdR — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.81 GFF4360 Queuosine Biosynthesis QueC ATPase 0.75 GFF4317 Ribonucleotide reductase transcriptional regulator NrdR low > 78
Erwinia tracheiphila SCR3 0.80 LU632_RS18310 queC 7-cyano-7-deazaguanine synthase QueC 0.89 LU632_RS18590 nrdR transcriptional regulator NrdR low > 74
Pseudomonas fluorescens FW300-N2E3 0.74 AO353_22170 7-cyano-7-deazaguanine synthase 0.68 AO353_06720 NrdR family transcriptional regulator low > 101
Pseudomonas fluorescens FW300-N1B4 0.74 Pf1N1B4_1527 Queuosine Biosynthesis QueC ATPase 0.68 Pf1N1B4_2648 Ribonucleotide reductase transcriptional regulator NrdR — —
Vibrio cholerae E7946 ATCC 55056 0.69 CSW01_06875 7-cyano-7-deazaguanine synthase QueC 0.80 CSW01_11565 transcriptional regulator NrdR low > 62
Shewanella loihica PV-4 0.68 Shew_2062 exsB protein (RefSeq) 0.78 Shew_1186 transcriptional regulator NrdR (RefSeq) — —
Shewanella amazonensis SB2B 0.68 Sama_1826 ExsB protein (RefSeq) 0.77 Sama_1015 nrdR transcriptional regulator NrdR (RefSeq) low > 62
Shewanella oneidensis MR-1 0.67 SO2503 exsB exsB protein (NCBI ptt file) 0.76 SO3470 conserved hypothetical protein TIGR00244 (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.67 Shewana3_2164 queuosine biosynthesis protein QueC (RefSeq) 0.76 Shewana3_1095 nrdR transcriptional regulator NrdR (RefSeq) low > 73
Herbaspirillum seropedicae SmR1 0.42 HSERO_RS20880 7-cyano-7-deazaguanine synthase 0.51 HSERO_RS06145 NrdR family transcriptional regulator low > 78
Variovorax sp. SCN45 0.41 GFF5214 7-cyano-7-deazaguanine synthase (EC 6.3.4.20) 0.47 GFF561 Ribonucleotide reductase transcriptional regulator NrdR low > 127
Paraburkholderia graminis OAS925 0.40 ABIE53_000396 7-cyano-7-deazaguanine synthase 0.46 ABIE53_000889 transcriptional repressor NrdR 0.48 46
Acidovorax sp. GW101-3H11 0.39 Ac3H11_4838 Queuosine Biosynthesis QueC ATPase 0.40 Ac3H11_2922 Ribonucleotide reductase transcriptional regulator NrdR — —
Burkholderia phytofirmans PsJN 0.39 BPHYT_RS01500 7-cyano-7-deazaguanine synthase 0.45 BPHYT_RS03730 transcriptional repressor NrdR low > 109
Paraburkholderia bryophila 376MFSha3.1 0.39 H281DRAFT_02232 preQ(0) biosynthesis protein QueC 0.46 H281DRAFT_04727 transcriptional repressor NrdR low > 103
Rhodopseudomonas palustris CGA009 0.39 TX73_014550 7-cyano-7-deazaguanine synthase QueC 0.43 TX73_014120 transcriptional regulator NrdR — —
Paraburkholderia sabiae LMG 24235 0.39 QEN71_RS00200 7-cyano-7-deazaguanine synthase QueC 0.46 QEN71_RS26230 transcriptional regulator NrdR low > 153
Castellaniella sp019104865 MT123 0.39 ABCV34_RS10950 7-cyano-7-deazaguanine synthase QueC 0.45 ABCV34_RS10550 transcriptional regulator NrdR low > 48
Caulobacter crescentus NA1000 Δfur 0.38 CCNA_03262 queuosine biosynthesis protein QueC 0.42 CCNA_01420 NrdR family transcriptional regulator low > 67
Caulobacter crescentus NA1000 0.38 CCNA_03262 queuosine biosynthesis protein QueC 0.42 CCNA_01420 NrdR family transcriptional regulator low > 66
Bosea sp. OAE506 0.38 ABIE41_RS11340 7-cyano-7-deazaguanine synthase QueC 0.42 ABIE41_RS19765 transcriptional regulator NrdR — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.37 GFF1402 Queuosine Biosynthesis QueC ATPase 0.49 GFF5153 Ribonucleotide reductase transcriptional regulator NrdR low > 90
Brevundimonas sp. GW460-12-10-14-LB2 0.36 A4249_RS08700 7-cyano-7-deazaguanine synthase QueC 0.46 A4249_RS06035 transcriptional regulator NrdR — —
Pseudomonas stutzeri RCH2 0.30 Psest_1506 queuosine biosynthesis protein QueC 0.71 Psest_3553 transcriptional regulator NrdR — —
Pseudomonas sp. S08-1 0.29 OH686_19180 queuosine biosynthesis protein QueC 0.70 OH686_15690 transcriptional regulator NrdR low > 80
Pseudomonas fluorescens FW300-N2C3 0.29 AO356_18070 7-cyano-7-deazaguanine synthase 0.68 AO356_14925 NrdR family transcriptional regulator — —
Acinetobacter radioresistens SK82 0.29 MPMX26_02175 7-cyano-7-deazaguanine synthase 0.60 MPMX26_00151 Transcriptional repressor NrdR low > 36
Pseudomonas simiae WCS417 0.29 PS417_22400 7-cyano-7-deazaguanine synthase 0.68 PS417_25270 NrdR family transcriptional regulator low > 88
Kangiella aquimarina DSM 16071 0.29 B158DRAFT_1146 preQ(0) biosynthesis protein QueC 0.71 B158DRAFT_1909 transcriptional regulator NrdR low > 40
Pseudomonas fluorescens SBW25 0.29 PFLU_RS24040 7-cyano-7-deazaguanine synthase QueC 0.66 PFLU_RS26905 transcriptional regulator NrdR low > 109
Pseudomonas fluorescens SBW25-INTG 0.29 PFLU_RS24040 7-cyano-7-deazaguanine synthase QueC 0.66 PFLU_RS26905 transcriptional regulator NrdR low > 109
Pseudomonas putida KT2440 0.29 PP_1226 pre-queuosine 0 synthase 0.68 PP_0513 DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP low > 96
Pseudomonas syringae pv. syringae B728a 0.28 Psyr_1419 preQ(0) biosynthesis protein QueC 0.68 Psyr_4463 Protein of unknown function DUF193 low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.28 Psyr_1419 preQ(0) biosynthesis protein QueC 0.68 Psyr_4463 Protein of unknown function DUF193 low > 86
Ralstonia solanacearum UW163 0.28 UW163_RS00625 7-cyano-7-deazaguanine synthase QueC 0.48 UW163_RS00675 transcriptional regulator NrdR — —
Ralstonia solanacearum IBSBF1503 0.28 RALBFv3_RS12940 7-cyano-7-deazaguanine synthase QueC 0.48 RALBFv3_RS12890 transcriptional regulator NrdR low > 76
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS10785 7-cyano-7-deazaguanine synthase QueC 0.61 ABZR86_RS10710 transcriptional regulator NrdR low > 74
Ralstonia solanacearum PSI07 0.28 RPSI07_RS20285 7-cyano-7-deazaguanine synthase QueC 0.47 RPSI07_RS20335 transcriptional regulator NrdR low > 81
Lysobacter sp. OAE881 0.28 ABIE51_RS05105 7-cyano-7-deazaguanine synthase QueC 0.54 ABIE51_RS04625 transcriptional regulator NrdR — —
Ralstonia solanacearum GMI1000 0.27 RS_RS03715 7-cyano-7-deazaguanine synthase 0.47 RS_RS03665 transcriptional regulator NrdR low > 80
Pseudomonas fluorescens GW456-L13 0.27 PfGW456L13_1862 Queuosine Biosynthesis QueC ATPase 0.68 PfGW456L13_1312 Ribonucleotide reductase transcriptional regulator NrdR low > 87
Ralstonia sp. UNC404CL21Col 0.27 ABZR87_RS09000 7-cyano-7-deazaguanine synthase QueC 0.47 ABZR87_RS08950 transcriptional regulator NrdR low > 80
Xanthomonas campestris pv. campestris strain 8004 0.27 Xcc-8004.1450.1 Queuosine Biosynthesis QueC ATPase 0.54 Xcc-8004.4397.1 Ribonucleotide reductase transcriptional regulator NrdR — —
Cupriavidus basilensis FW507-4G11 0.27 RR42_RS15445 7-cyano-7-deazaguanine synthase 0.50 RR42_RS15490 NrdR family transcriptional regulator low > 128
Rhodanobacter sp. FW510-T8 0.26 OKGIIK_01895 queC 7-cyano-7-deazaguanine synthase QueC 0.60 OKGIIK_11435 nrdR transcriptional regulator NrdR low > 52
Dechlorosoma suillum PS 0.26 Dsui_0549 queuosine biosynthesis protein QueC 0.49 Dsui_1266 transcriptional regulator NrdR low > 51
Rhodanobacter denitrificans MT42 0.26 LRK55_RS04635 7-cyano-7-deazaguanine synthase QueC 0.59 LRK55_RS04390 transcriptional regulator NrdR low > 63
Rhodanobacter denitrificans FW104-10B01 0.26 LRK54_RS04855 7-cyano-7-deazaguanine synthase QueC 0.59 LRK54_RS04615 transcriptional regulator NrdR low > 59
Rhodospirillum rubrum S1H 0.26 Rru_A1957 ExsB (NCBI) 0.43 Rru_A1826 Protein of unknown function DUF193 (NCBI) — —
Alteromonas macleodii MIT1002 0.26 MIT1002_01263 7-cyano-7-deazaguanine synthase 0.77 MIT1002_02701 Transcriptional repressor NrdR low > 70
Magnetospirillum magneticum AMB-1 0.26 AMB_RS20345 7-cyano-7-deazaguanine synthase 0.44 AMB_RS04725 transcriptional regulator NrdR 0.56 17
Azospirillum sp. SherDot2 0.25 MPMX19_00425 7-cyano-7-deazaguanine synthase 0.45 MPMX19_00728 Transcriptional repressor NrdR low > 112
Azospirillum brasilense Sp245 0.25 AZOBR_RS04150 7-cyano-7-deazaguanine synthase 0.46 AZOBR_RS10020 NrdR family transcriptional regulator — —
Synechococcus elongatus PCC 7942 0.24 Synpcc7942_1333 ExsB 0.35 Synpcc7942_0695 hypothetical protein low > 38
Marinobacter adhaerens HP15 0.23 HP15_3814 ExsB protein 0.69 HP15_491 transcriptional repressor NrdR low > 73
Sphingomonas koreensis DSMZ 15582 0.22 Ga0059261_3209 queuosine biosynthesis protein QueC 0.44 Ga0059261_1985 transcriptional regulator NrdR low > 68
Agrobacterium fabrum C58 0.17 Atu3346 succinoglycan biosynthesis regulator 0.42 Atu1166 hypothetical protein — —
Sinorhizobium meliloti 1021 0.17 SM_b20940 hypothetical protein 0.43 SMc01771 transcriptional regulator NrdR — —
Phaeobacter inhibens DSM 17395 0.17 PGA1_c05600 queuosine biosynthesis protein QueC 0.40 PGA1_c08860 transcriptional repressor — —

Not shown: 12 genomes with orthologs for EX31_RS22280 only; 6 genomes with orthologs for EX31_RS22120 only