Conservation of cofitness between EX28DRAFT_3670 and EX28DRAFT_3669 in Enterobacter asburiae PDN3

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Enterobacter asburiae PDN3 1.0 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) 1.0 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.97 2
Enterobacter sp. TBS_079 0.99 MPMX20_00769 2-isopropylmalate synthase 0.99 MPMX20_00768 3-isopropylmalate dehydrogenase 0.97 1
Klebsiella pneumoniae MKP103 0.96 KDGMDA_12910 2-isopropylmalate synthase 0.95 KDGMDA_12905 3-isopropylmalate dehydrogenase low > 95
Klebsiella michiganensis M5al 0.96 BWI76_RS04680 2-isopropylmalate synthase 0.95 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.95 5
Escherichia coli BW25113 0.94 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.93 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.98 2
Escherichia coli BL21 0.94 ECD_00076 2-isopropylmalate synthase 0.93 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.97 2
Escherichia coli ECRC62 0.94 BNILDI_08550 2-isopropylmalate synthase 0.93 BNILDI_08545 leuA 2-isopropylmalate synthase 0.98 10
Escherichia coli Nissle 1917 0.94 ECOLIN_RS00400 2-isopropylmalate synthase 0.94 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.96 8
Escherichia fergusonii Becca 0.94 EFB2_03971 2-isopropylmalate synthase 0.94 EFB2_03972 3-isopropylmalate dehydrogenase low > 86
Escherichia coli ECOR27 0.94 NOLOHH_03060 2-isopropylmalate synthase 0.93 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.98 8
Escherichia coli ECOR38 0.94 HEPCGN_08695 2-isopropylmalate synthase 0.94 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.97 19
Escherichia coli HS(pFamp)R (ATCC 700891) 0.94 OHPLBJKB_03583 2-isopropylmalate synthase 0.93 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 74
Escherichia coli ECRC98 0.94 JDDGAC_14310 2-isopropylmalate synthase 0.94 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase 0.96 9
Escherichia coli ECRC101 0.94 MCAODC_01230 2-isopropylmalate synthase 0.94 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.98 2
Escherichia coli ECRC99 0.94 KEDOAH_17440 2-isopropylmalate synthase 0.94 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC100 0.94 OKFHMN_10715 2-isopropylmalate synthase 0.94 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.99 19
Escherichia coli ECRC102 0.94 NIAGMN_08565 2-isopropylmalate synthase 0.94 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase 0.99 4
Erwinia tracheiphila HP pepo 2.2 0.86 IJEDHG_05995 leuA 2-isopropylmalate synthase 0.82 IJEDHG_06000 leuB 3-isopropylmalate dehydrogenase 0.92 3
Erwinia tracheiphila SCR3 0.86 LU632_RS02880 leuA 2-isopropylmalate synthase 0.82 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.95 2
Dickeya dadantii 3937 0.86 DDA3937_RS18115 2-isopropylmalate synthase 0.88 DDA3937_RS18120 3-isopropylmalate dehydrogenase 0.96 2
Pectobacterium carotovorum WPP14 0.86 HER17_RS03085 2-isopropylmalate synthase 0.87 HER17_RS03080 3-isopropylmalate dehydrogenase 0.98 9
Dickeya dianthicola ME23 0.85 DZA65_RS19200 2-isopropylmalate synthase 0.87 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.97 1
Dickeya dianthicola 67-19 0.85 HGI48_RS18055 2-isopropylmalate synthase 0.88 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.95 1
Serratia liquefaciens MT49 0.85 IAI46_03355 2-isopropylmalate synthase 0.87 IAI46_03350 3-isopropylmalate dehydrogenase 0.58 31
Pantoea agglomerans CFBP13505 P0401 0.84 PagCFBP13505_RS13000 2-isopropylmalate synthase 0.82 PagCFBP13505_RS12995 3-isopropylmalate dehydrogenase low > 74
Pantoea sp. MT58 0.84 IAI47_16000 2-isopropylmalate synthase 0.82 IAI47_16005 3-isopropylmalate dehydrogenase 0.99 3
Erwinia amylovora T8 0.84 OLJFJH_01285 2-isopropylmalate synthase 0.85 OLJFJH_01290 3-isopropylmalate dehydrogenase 0.97 1
Rahnella sp. WP5 0.81 EX31_RS03680 2-isopropylmalate synthase 0.87 EX31_RS03685 3-isopropylmalate dehydrogenase 0.96 8
Vibrio cholerae E7946 ATCC 55056 0.68 CSW01_12595 2-isopropylmalate synthase 0.77 CSW01_12600 3-isopropylmalate dehydrogenase low > 62
Shewanella amazonensis SB2B 0.67 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.69 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.97 2
Shewanella oneidensis MR-1 0.66 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.70 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.99 1
Shewanella sp. ANA-3 0.66 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.70 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.98 3
Shewanella loihica PV-4 0.66 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.69 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.99 2
Alteromonas macleodii MIT1002 0.61 MIT1002_00949 2-isopropylmalate synthase 0.63 MIT1002_00948 3-isopropylmalate dehydrogenase 0.99 2
Pseudomonas stutzeri RCH2 0.47 Psest_1056 2-isopropylmalate synthase, bacterial type 0.51 Psest_2589 3-isopropylmalate dehydrogenase low > 67
Dechlorosoma suillum PS 0.46 Dsui_3519 2-isopropylmalate synthase, bacterial type 0.51 Dsui_3198 3-isopropylmalate dehydrogenase — —
Marinobacter adhaerens HP15 0.44 HP15_538 2-isopropylmalate synthase 0.50 HP15_1832 3-isopropylmalate dehydrogenase low > 73
Methylophilus sp. DMC18 0.44 GFF1746 2-isopropylmalate synthase 0.51 GFF648 3-isopropylmalate dehydrogenase — —
Parabacteroides merdae CL09T00C40 0.43 HMPREF1078_RS16665 2-isopropylmalate synthase 0.42 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.96 3
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS14545 2-isopropylmalate synthase 0.44 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.86 26
Synechocystis sp000284455 PCC 6803 0.43 SGL_RS12850 2-isopropylmalate synthase 0.49 SGL_RS09375 3-isopropylmalate dehydrogenase — —
Phocaeicola dorei CL03T12C01 0.43 ABI39_RS10195 2-isopropylmalate synthase 0.44 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.86 4
Desulfovibrio vulgaris Miyazaki F 0.42 DvMF_1791 2-isopropylmalate synthase (RefSeq) 0.52 DvMF_1794 3-isopropylmalate dehydrogenase (RefSeq) 0.94 2
Desulfovibrio vulgaris Hildenborough JW710 0.42 DVU2981 leuA 2-isopropylmalate synthase (TIGR) 0.53 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) 0.98 1
Magnetospirillum magneticum AMB-1 0.42 AMB_RS17765 2-isopropylmalate synthase 0.44 AMB_RS20570 3-isopropylmalate dehydrogenase — —
Bosea sp. OAE506 0.42 ABIE41_RS13000 2-isopropylmalate synthase 0.42 ABIE41_RS11860 3-isopropylmalate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.42 TX73_010545 2-isopropylmalate synthase 0.44 TX73_001175 3-isopropylmalate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.42 H281DRAFT_04556 2-isopropylmalate synthase 0.48 H281DRAFT_06072 3-isopropylmalate dehydrogenase low > 103
Paraburkholderia graminis OAS925 0.42 ABIE53_001580 2-isopropylmalate synthase 0.48 ABIE53_004804 3-isopropylmalate dehydrogenase low > 113
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS14150 2-isopropylmalate synthase 0.42 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.96 2
Bacteroides ovatus ATCC 8483 0.41 BACOVA_04604 2-isopropylmalate synthase 0.43 BACOVA_04600 3-isopropylmalate dehydrogenase 0.93 20
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS06570 2-isopropylmalate synthase 0.48 BPHYT_RS33900 3-isopropylmalate dehydrogenase low > 109
Paraburkholderia sabiae LMG 24235 0.41 QEN71_RS24195 2-isopropylmalate synthase 0.48 QEN71_RS17620 3-isopropylmalate dehydrogenase low > 153
Bacteroides thetaiotaomicron VPI-5482 0.41 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) 0.43 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.90 27
Synechococcus elongatus PCC 7942 0.41 Synpcc7942_1410 leuA 2-isopropylmalate synthase 0.47 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF4281 2-isopropylmalate synthase (EC 2.3.3.13) 0.49 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.56 26
Ralstonia solanacearum UW163 0.41 UW163_RS10700 2-isopropylmalate synthase 0.47 UW163_RS11115 3-isopropylmalate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.41 RALBFv3_RS03025 2-isopropylmalate synthase 0.47 RALBFv3_RS02610 3-isopropylmalate dehydrogenase low > 76
Ralstonia solanacearum PSI07 0.41 RPSI07_RS14285 2-isopropylmalate synthase 0.47 RPSI07_RS14705 3-isopropylmalate dehydrogenase 0.48 4
Xanthobacter sp. DMC5 0.41 GFF2400 2-isopropylmalate synthase 0.43 GFF1695 3-isopropylmalate dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.41 ABZR86_RS15970 2-isopropylmalate synthase 0.37 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.97 12
Ralstonia solanacearum GMI1000 0.41 RS_RS10395 2-isopropylmalate synthase 0.48 RS_RS09990 3-isopropylmalate dehydrogenase low > 80
Ralstonia sp. UNC404CL21Col 0.41 ABZR87_RS14930 2-isopropylmalate synthase 0.47 ABZR87_RS14530 3-isopropylmalate dehydrogenase low > 80
Variovorax sp. SCN45 0.41 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) 0.50 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 127
Cupriavidus basilensis FW507-4G11 0.40 RR42_RS05465 2-isopropylmalate synthase 0.47 RR42_RS14385 3-isopropylmalate dehydrogenase 0.36 30
Variovorax sp. OAS795 0.40 ABID97_RS14910 2-isopropylmalate synthase 0.50 ABID97_RS08455 3-isopropylmalate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.40 Ac3H11_530 2-isopropylmalate synthase (EC 2.3.3.13) 0.50 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.45 28
Caulobacter crescentus NA1000 0.40 CCNA_01610 2-isopropylmalate synthase 0.42 CCNA_00193 3-isopropylmalate dehydrogenase 0.84 16
Caulobacter crescentus NA1000 Δfur 0.40 CCNA_01610 2-isopropylmalate synthase 0.42 CCNA_00193 3-isopropylmalate dehydrogenase low > 67
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS10345 2-isopropylmalate synthase 0.39 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.90 3
Rhodanobacter denitrificans MT42 0.39 LRK55_RS09985 2-isopropylmalate synthase 0.40 LRK55_RS09965 3-isopropylmalate dehydrogenase low > 63
Lysobacter sp. OAE881 0.39 ABIE51_RS17570 2-isopropylmalate synthase 0.41 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.86 17
Rhodanobacter sp000427505 FW510-R12 0.39 LRK53_RS03120 2-isopropylmalate synthase 0.41 LRK53_RS03100 3-isopropylmalate dehydrogenase 0.90 1
Phaeobacter inhibens DSM 17395 0.39 PGA1_c26470 2-isopropylmalate synthase LeuA 0.48 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.95 1
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_13575 leuA 2-isopropylmalate synthase 0.39 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase 0.94 4
Dinoroseobacter shibae DFL-12 0.38 Dshi_0596 2-isopropylmalate synthase (RefSeq) 0.46 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) — —
Xanthomonas campestris pv. campestris strain 8004 0.38 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) 0.49 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.88 3
Methanococcus maripaludis JJ 0.29 MMJJ_RS08870 2-isopropylmalate synthase 0.27 MMJJ_RS02220 3-isopropylmalate dehydrogenase — —
Methanococcus maripaludis S2 0.29 MMP_RS05500 2-isopropylmalate synthase 0.26 MMP_RS02855 3-isopropylmalate dehydrogenase — —
Sinorhizobium meliloti 1021 0.15 SMc02546 alpha-isopropylmalate/homocitrate synthase family transferase 0.44 SMc04405 3-isopropylmalate dehydrogenase low > 103
Rhizobium sp. OAE497 0.15 ABIE40_RS06220 citramalate synthase 0.43 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.68 17

Not shown: 0 genomes with orthologs for EX28DRAFT_3670 only; 42 genomes with orthologs for EX28DRAFT_3669 only