Conservation of cofitness between ECD_03809 and ECD_03883 in Escherichia coli BL21

83 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03809 ferredoxin-NADP reductase; flavodoxin reductase 1.0 ECD_03883 IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase low > 61
Escherichia coli ECRC98 1.00 JDDGAC_17410 fpr ferredoxin--NADP(+) reductase 1.00 JDDGAC_16935 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 86
Escherichia coli ECRC100 1.00 OKFHMN_13785 fpr ferredoxin--NADP(+) reductase 1.00 OKFHMN_13310 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 80
Escherichia coli ECRC99 1.00 KEDOAH_14375 fpr ferredoxin--NADP(+) reductase 1.00 KEDOAH_14850 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECRC101 1.00 MCAODC_04285 fpr ferredoxin--NADP(+) reductase 1.00 MCAODC_03810 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 87
Escherichia coli ECRC102 1.00 NIAGMN_11540 fpr ferredoxin--NADP(+) reductase 1.00 NIAGMN_11060 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECOR38 0.99 HEPCGN_12430 fpr ferredoxin--NADP(+) reductase 0.99 HEPCGN_11950 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 87
Escherichia coli ECOR27 0.99 NOLOHH_05920 fpr ferredoxin--NADP(+) reductase 1.00 NOLOHH_05455 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Escherichia coli ECRC62 0.99 BNILDI_05610 fpr ferredoxin--NADP(+) reductase 0.99 BNILDI_06065 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_04127 Flavodoxin/ferredoxin--NADP reductase 0.99 OHPLBJKB_04043 Bifunctional purine biosynthesis protein PurH low > 73
Escherichia coli Nissle 1917 0.98 ECOLIN_RS22600 ferredoxin--NADP(+) reductase 0.99 ECOLIN_RS23100 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 55
Escherichia coli BW25113 0.98 b3924 fpr ferredoxin-NADP reductase (NCBI) 1.00 b4006 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) 0.31 24
Escherichia fergusonii Becca 0.98 EFB2_04694 Flavodoxin/ferredoxin--NADP reductase 0.99 EFB2_04604 Bifunctional purine biosynthesis protein PurH low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2305 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.96 GFF4186 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 78
Enterobacter sp. TBS_079 0.92 MPMX20_04545 Flavodoxin/ferredoxin--NADP reductase 0.94 MPMX20_00226 Bifunctional purine biosynthesis protein PurH low > 85
Enterobacter asburiae PDN3 0.91 EX28DRAFT_4397 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.94 EX28DRAFT_4545 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) — —
Klebsiella michiganensis M5al 0.90 BWI76_RS27450 ferredoxin--NADP(+) reductase 0.94 BWI76_RS01615 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase low > 92
Rahnella sp. WP5 0.80 EX31_RS14285 ferredoxin--NADP(+) reductase 0.88 EX31_RS16860 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.32 63
Pectobacterium carotovorum WPP14 0.80 HER17_RS00815 ferredoxin--NADP(+) reductase 0.90 HER17_RS20335 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Serratia liquefaciens MT49 0.80 IAI46_24620 ferredoxin--NADP(+) reductase 0.89 IAI46_01365 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 86
Dickeya dianthicola ME23 0.80 DZA65_RS21540 ferredoxin--NADP(+) reductase 0.90 DZA65_RS01260 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Dickeya dianthicola 67-19 0.79 HGI48_RS20495 ferredoxin--NADP(+) reductase 0.90 HGI48_RS01215 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 71
Dickeya dadantii 3937 0.78 DDA3937_RS00880 ferredoxin--NADP(+) reductase 0.91 DDA3937_RS01220 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pantoea sp. MT58 0.78 IAI47_00810 ferredoxin--NADP(+) reductase 0.90 IAI47_18040 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 76
Erwinia tracheiphila SCR3 0.75 LU632_RS19715 fpr ferredoxin--NADP(+) reductase 0.88 LU632_RS01020 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 74
Shewanella amazonensis SB2B 0.44 Sama_0663 ferredoxin--NADP reductase (RefSeq) 0.76 Sama_0395 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 62
Shewanella loihica PV-4 0.44 Shew_0858 oxidoreductase FAD/NAD(P)-binding subunit (RefSeq) 0.77 Shew_3412 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 60
Shewanella sp. ANA-3 0.40 Shewana3_3520 oxidoreductase FAD/NAD(P)-binding subunit (RefSeq) 0.74 Shewana3_0441 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.40 SO0747 fpr ferredoxin--NADP reductase (NCBI ptt file) 0.73 SO0442 purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI ptt file) low > 76
Pseudomonas simiae WCS417 0.40 PS417_24325 ferredoxin-NADP reductase 0.69 PS417_02940 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.39 PFLU_RS26250 ferredoxin--NADP reductase 0.69 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Pseudomonas fluorescens SBW25 0.39 PFLU_RS26250 ferredoxin--NADP reductase 0.69 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH low > 109
Pseudomonas fluorescens FW300-N2E2 0.39 Pf6N2E2_5072 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.69 Pf6N2E2_3519 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas sp. S08-1 0.39 OH686_16145 Ferredoxin--NADP(+) reductase or Flavodoxin--NADP(+) reductase 0.69 OH686_07620 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas stutzeri RCH2 0.39 Psest_3439 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.68 Psest_1014 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas fluorescens FW300-N2C3 0.39 AO356_15660 ferredoxin-NADP reductase 0.69 AO356_08225 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas sp. RS175 0.38 PFR28_03796 Flavodoxin/ferredoxin--NADP reductase 0.69 PFR28_05214 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas fluorescens FW300-N2E3 0.38 AO353_13960 ferredoxin-NADP reductase 0.69 AO353_13650 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.38 Psyr_4277 Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.38 Psyr_4277 Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_1440 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.69 PfGW456L13_57 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Acinetobacter radioresistens SK82 0.37 MPMX26_02540 Flavodoxin/ferredoxin--NADP reductase 0.69 MPMX26_01141 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas fluorescens FW300-N1B4 0.37 Pf1N1B4_2764 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.70 Pf1N1B4_1315 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 87
Pseudomonas putida KT2440 0.36 PP_4646 ferredoxin--NADP(+) reductase 0.68 PP_4822 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS07730 ferredoxin-NADP reductase 0.58 HSERO_RS02060 purine biosynthesis protein purH — —
Dechlorosoma suillum PS 0.31 Dsui_2127 flavodoxin reductase family protein 0.54 Dsui_1595 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Paraburkholderia graminis OAS925 0.30 ABIE53_000451 ferredoxin--NADP+ reductase 0.61 ABIE53_003491 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS26685 ferredoxin-NADP reductase 0.59 RR42_RS02720 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Paraburkholderia bryophila 376MFSha3.1 0.29 H281DRAFT_02177 ferredoxin--NADP+ reductase 0.61 H281DRAFT_04251 IMP cyclohydrolase /phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Burkholderia phytofirmans PsJN 0.29 BPHYT_RS01800 ferredoxin--NADP reductase 0.60 BPHYT_RS16595 bifunctional purine biosynthesis protein PurH — —
Paraburkholderia sabiae LMG 24235 0.29 QEN71_RS00515 ferredoxin--NADP reductase 0.60 QEN71_RS26780 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Azospirillum brasilense Sp245 0.29 AZOBR_RS02415 ferredoxin--NADP reductase 0.51 AZOBR_RS00225 purine biosynthesis protein purH — —
Alteromonas macleodii MIT1002 0.28 MIT1002_02652 Ferredoxin--NADP reductase 0.76 MIT1002_03959 Bifunctional purine biosynthesis protein PurH — —
Castellaniella sp019104865 MT123 0.28 ABCV34_RS03560 ferredoxin--NADP reductase 0.54 ABCV34_RS07970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS18185 ferredoxin--NADP reductase 0.61 ABZR86_RS17045 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Marinobacter adhaerens HP15 0.28 HP15_2200 oxidoreductase FAD/NAD(P)-binding domain protein 0.72 HP15_3227 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Azospirillum sp. SherDot2 0.28 MPMX19_05828 Ferredoxin--NADP reductase 0.54 MPMX19_02325 Bifunctional purine biosynthesis protein PurH — —
Rhodospirillum rubrum S1H 0.28 Rru_A0530 Ferredoxin--NADP+ reductase (NCBI) 0.49 Rru_A3655 Phosphoribosylaminoimidazolecarboxamideformyltransferase (NCBI) — —
Rhodanobacter denitrificans MT42 0.27 LRK55_RS05870 ferredoxin--NADP reductase 0.59 LRK55_RS06570 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 63
Rhodanobacter denitrificans FW104-10B01 0.27 LRK54_RS06125 ferredoxin--NADP reductase 0.58 LRK54_RS06825 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rhodanobacter sp. FW510-T8 0.27 OKGIIK_00495 fpr ferredoxin--NADP(+) reductase 0.58 OKGIIK_16805 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Bosea sp. OAE506 0.26 ABIE41_RS10365 ferredoxin--NADP reductase 0.51 ABIE41_RS05095 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Xanthomonas campestris pv. campestris strain 8004 0.26 Xcc-8004.3508.1 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.56 Xcc-8004.659.1 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Acidovorax sp. GW101-3H11 0.26 Ac3H11_3439 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.54 Ac3H11_3994 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Ralstonia sp. UNC404CL21Col 0.26 ABZR87_RS11335 ferredoxin--NADP reductase 0.59 ABZR87_RS07640 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rhizobium sp. OAE497 0.26 ABIE40_RS09225 ferredoxin--NADP reductase 0.47 ABIE40_RS19130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Ralstonia solanacearum UW163 0.25 UW163_RS13210 ferredoxin--NADP reductase 0.59 UW163_RS01900 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Agrobacterium fabrum C58 0.25 Atu1458 ferredoxin NADP+ reductase 0.46 Atu2823 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Lysobacter sp. OAE881 0.25 ABIE51_RS09180 ferredoxin--NADP reductase 0.57 ABIE51_RS17760 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Ralstonia solanacearum IBSBF1503 0.25 RALBFv3_RS15765 ferredoxin--NADP reductase 0.59 RALBFv3_RS11685 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.25 GFF4298 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.56 GFF636 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Sinorhizobium meliloti 1021 0.25 SMc02122 ferredoxin--NADP reductase 0.47 SMc04088 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Variovorax sp. SCN45 0.25 GFF6387 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) @ Flavodoxin--NADP(+) reductase (EC 1.19.1.1) 0.55 GFF2146 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Rhodopseudomonas palustris CGA009 0.25 TX73_008105 ferredoxin--NADP reductase 0.52 TX73_000145 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Ralstonia solanacearum GMI1000 0.25 RS_RS06545 ferredoxin--NADP reductase 0.59 RS_RS02505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase — —
Ralstonia solanacearum PSI07 0.25 RPSI07_RS17600 ferredoxin--NADP reductase 0.59 RPSI07_RS21530 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Variovorax sp. OAS795 0.23 ABID97_RS03500 ferredoxin--NADP reductase 0.55 ABID97_RS24725 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Phaeobacter inhibens DSM 17395 0.23 PGA1_c20790 ferredoxin--NADP reductase Fpr 0.52 PGA1_c32860 bifunctional purine biosynthesis protein PurH — —
Sphingomonas koreensis DSMZ 15582 0.23 Ga0059261_3758 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.49 Ga0059261_2242 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.22 A4249_RS06545 ferredoxin--NADP reductase 0.44 A4249_RS13150 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Caulobacter crescentus NA1000 0.22 CCNA_03314 ferredoxin-NADP reductase 0.47 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 66
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_03314 ferredoxin-NADP reductase 0.47 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 67
Dinoroseobacter shibae DFL-12 0.20 Dshi_1150 Ferredoxin--NADP(+) reductase (RefSeq) 0.50 Dshi_0358 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) — —
Kangiella aquimarina DSM 16071 0.14 B158DRAFT_1395 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.71 B158DRAFT_0166 IMP cyclohydrolase (EC 3.5.4.10)/phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —

Not shown: 0 genomes with orthologs for ECD_03809 only; 16 genomes with orthologs for ECD_03883 only