Conservation of cofitness between ECD_02735 and ECD_02737 in Escherichia coli BL21

83 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_02735 glycine decarboxylase, PLP-dependent, subunit P of glycine cleavage complex 1.0 ECD_02737 aminomethyltransferase, tetrahydrofolate-dependent, subunit (T protein) of glycine cleavage complex 0.40 33
Escherichia coli ECRC62 1.00 BNILDI_09980 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 BNILDI_09970 gcvT glycine cleavage system aminomethyltransferase GcvT low > 75
Escherichia coli BW25113 1.00 b2903 gcvP glycine dehydrogenase (NCBI) 1.00 b2905 gcvT glycine cleavage system aminomethyltransferase T (NCBI) 0.94 1
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00812 Glycine dehydrogenase (decarboxylating) 1.00 OHPLBJKB_00810 Aminomethyltransferase 0.78 2
Escherichia coli ECRC98 1.00 JDDGAC_23170 gcvP aminomethyl-transferring glycine dehydrogenase 0.99 JDDGAC_23160 gcvT glycine cleavage system aminomethyltransferase GcvT low > 86
Escherichia coli ECRC102 1.00 NIAGMN_17295 gcvP aminomethyl-transferring glycine dehydrogenase 0.99 NIAGMN_17285 gcvT glycine cleavage system aminomethyltransferase GcvT — —
Escherichia coli ECRC99 1.00 KEDOAH_08610 gcvP aminomethyl-transferring glycine dehydrogenase 0.99 KEDOAH_08620 gcvT glycine cleavage system aminomethyltransferase GcvT — —
Escherichia coli ECRC101 1.00 MCAODC_10050 gcvP aminomethyl-transferring glycine dehydrogenase 0.99 MCAODC_10040 gcvT glycine cleavage system aminomethyltransferase GcvT low > 87
Escherichia coli ECRC100 1.00 OKFHMN_19530 gcvP aminomethyl-transferring glycine dehydrogenase 0.99 OKFHMN_19520 gcvT glycine cleavage system aminomethyltransferase GcvT 0.69 8
Escherichia coli Nissle 1917 0.99 ECOLIN_RS16165 aminomethyl-transferring glycine dehydrogenase 0.99 ECOLIN_RS16175 glycine cleavage system aminomethyltransferase GcvT 0.82 1
Escherichia coli ECOR38 0.99 HEPCGN_18820 gcvP aminomethyl-transferring glycine dehydrogenase 0.99 HEPCGN_18810 gcvT glycine cleavage system aminomethyltransferase GcvT 0.87 1
Escherichia fergusonii Becca 0.99 EFB2_00999 Glycine dehydrogenase (decarboxylating) 0.99 EFB2_00997 Aminomethyltransferase low > 86
Escherichia coli ECOR27 0.99 NOLOHH_11445 gcvP aminomethyl-transferring glycine dehydrogenase 1.00 NOLOHH_11435 gcvT glycine cleavage system aminomethyltransferase GcvT 0.88 1
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF3003 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.95 GFF3005 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) low > 78
Enterobacter sp. TBS_079 0.89 MPMX20_03762 Glycine dehydrogenase (decarboxylating) 0.91 MPMX20_03764 Aminomethyltransferase 0.90 1
Klebsiella michiganensis M5al 0.89 BWI76_RS23870 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) 0.90 BWI76_RS23880 Aminomethyltransferase (EC 2.1.2.10) (from data) 0.75 1
Enterobacter asburiae PDN3 0.88 EX28DRAFT_2955 glycine dehydrogenase (decarboxylating) 0.92 EX28DRAFT_2957 glycine cleavage system T protein 0.67 10
Pantoea sp. MT58 0.82 IAI47_03775 aminomethyl-transferring glycine dehydrogenase 0.82 IAI47_03765 glycine cleavage system aminomethyltransferase GcvT 0.46 34
Serratia liquefaciens MT49 0.81 IAI46_20850 aminomethyl-transferring glycine dehydrogenase 0.86 IAI46_20860 glycine cleavage system aminomethyltransferase GcvT low > 86
Erwinia tracheiphila SCR3 0.81 LU632_RS05915 gcvP aminomethyl-transferring glycine dehydrogenase 0.82 LU632_RS05905 gcvT glycine cleavage system aminomethyltransferase GcvT low > 74
Rahnella sp. WP5 0.81 EX31_RS21520 aminomethyl-transferring glycine dehydrogenase 0.84 EX31_RS21510 glycine cleavage system aminomethyltransferase GcvT 0.56 1
Pectobacterium carotovorum WPP14 0.80 HER17_RS17995 aminomethyl-transferring glycine dehydrogenase 0.78 HER17_RS18005 glycine cleavage system aminomethyltransferase GcvT low > 75
Dickeya dadantii 3937 0.80 DDA3937_RS03255 aminomethyl-transferring glycine dehydrogenase 0.79 DDA3937_RS03245 glycine cleavage system aminomethyltransferase GcvT low > 74
Dickeya dianthicola 67-19 0.80 HGI48_RS03400 aminomethyl-transferring glycine dehydrogenase 0.79 HGI48_RS03390 glycine cleavage system aminomethyltransferase GcvT low > 71
Dickeya dianthicola ME23 0.80 DZA65_RS03445 aminomethyl-transferring glycine dehydrogenase 0.79 DZA65_RS03435 glycine cleavage system aminomethyltransferase GcvT low > 75
Shewanella amazonensis SB2B 0.68 Sama_2719 glycine dehydrogenase (RefSeq) 0.71 Sama_2721 gcvT glycine cleavage system aminomethyltransferase T (RefSeq) 0.97 1
Alteromonas macleodii MIT1002 0.68 MIT1002_02971 Glycine dehydrogenase [decarboxylating] 0.69 MIT1002_02973 Aminomethyltransferase 0.97 1
Shewanella sp. ANA-3 0.67 Shewana3_3499 glycine dehydrogenase (RefSeq) 0.69 Shewana3_3501 gcvT glycine cleavage system aminomethyltransferase T (RefSeq) 0.96 1
Shewanella oneidensis MR-1 0.67 SO0781 gcvP glycine cleavage system P protein (NCBI ptt file) 0.70 SO0779 gcvT glycine cleavage system T protein (NCBI ptt file) 0.98 1
Shewanella loihica PV-4 0.66 Shew_3062 glycine dehydrogenase (RefSeq) 0.69 Shew_3064 gcvT glycine cleavage system aminomethyltransferase T (RefSeq) 0.82 1
Pseudomonas sp. S08-1 0.63 OH686_11165 glycine dehydrogenase 0.57 OH686_11175 glycine cleavage system T protein 0.84 1
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_08720 glycine dehydrogenase 0.53 AO353_08735 glycine cleavage system protein T low > 101
Pseudomonas stutzeri RCH2 0.62 Psest_0183 glycine dehydrogenase (decarboxylating) 0.58 Psest_0181 glycine cleavage system T protein low > 67
Pseudomonas fluorescens GW456-L13 0.61 PfGW456L13_904 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.55 PfGW456L13_902 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) low > 87
Pseudomonas putida KT2440 0.61 PP_5192 glycine dehydrogenase 0.53 PP_5194 aminomethyltransferase low > 96
Dechlorosoma suillum PS 0.61 Dsui_2737 glycine dehydrogenase, decarboxylating 0.51 Dsui_2735 glycine cleavage system T protein low > 51
Kangiella aquimarina DSM 16071 0.58 B158DRAFT_0545 glycine dehydrogenase (decarboxylating) 0.61 B158DRAFT_0543 glycine cleavage system T protein — —
Vibrio cholerae E7946 ATCC 55056 0.58 CSW01_15330 glycine dehydrogenase (decarboxylating) 0.25 CSW01_15350 glycine cleavage system aminomethyltransferase T low > 62
Pseudomonas syringae pv. syringae B728a ΔmexB 0.56 Psyr_1096 glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit 0.55 Psyr_0246 aminomethyltransferase low > 86
Pseudomonas syringae pv. syringae B728a 0.56 Psyr_1096 glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit 0.55 Psyr_0246 aminomethyltransferase low > 86
Dyella japonica UNC79MFTsu3.2 0.56 ABZR86_RS08305 aminomethyl-transferring glycine dehydrogenase 0.55 ABZR86_RS18875 glycine cleavage system aminomethyltransferase GcvT 0.98 1
Rhodanobacter denitrificans MT42 0.56 LRK55_RS00260 aminomethyl-transferring glycine dehydrogenase 0.53 LRK55_RS05280 glycine cleavage system aminomethyltransferase GcvT low > 63
Pseudomonas sp. RS175 0.56 PFR28_03383 Glycine dehydrogenase (decarboxylating) 0.53 PFR28_04316 Aminomethyltransferase 0.48 1
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_5558 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) 0.53 Pf6N2E2_4485 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) low > 103
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_18170 glycine dehydrogenase 0.53 AO356_13035 glycine cleavage system protein T low > 104
Pseudomonas fluorescens SBW25 0.56 PFLU_RS24000 aminomethyl-transferring glycine dehydrogenase 0.54 PFLU_RS28915 glycine cleavage system aminomethyltransferase GcvT low > 109
Pseudomonas fluorescens SBW25-INTG 0.56 PFLU_RS24000 aminomethyl-transferring glycine dehydrogenase 0.54 PFLU_RS28915 glycine cleavage system aminomethyltransferase GcvT 0.35 107
Paraburkholderia bryophila 376MFSha3.1 0.56 H281DRAFT_02409 glycine dehydrogenase 0.48 H281DRAFT_02411 aminomethyltransferase 0.74 1
Pseudomonas simiae WCS417 0.56 PS417_22360 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) 0.55 PS417_27255 glycine cleavage system protein T low > 88
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS19330 glycine cleavage system P protein (EC 1.4.4.2) (from data) 0.48 BPHYT_RS19320 glycine cleavage system protein T 0.67 1
Paraburkholderia graminis OAS925 0.55 ABIE53_000238 glycine dehydrogenase 0.48 ABIE53_000236 aminomethyltransferase 0.81 1
Rhodanobacter denitrificans FW104-10B01 0.55 LRK54_RS00520 aminomethyl-transferring glycine dehydrogenase 0.53 LRK54_RS05510 glycine cleavage system aminomethyltransferase GcvT 0.79 1
Rhodopseudomonas palustris CGA009 0.55 TX73_019935 aminomethyl-transferring glycine dehydrogenase 0.25 TX73_019925 glycine cleavage system aminomethyltransferase GcvT 0.93 1
Paraburkholderia sabiae LMG 24235 0.55 QEN71_RS29215 aminomethyl-transferring glycine dehydrogenase 0.47 QEN71_RS29205 glycine cleavage system aminomethyltransferase GcvT 0.85 1
Cupriavidus basilensis FW507-4G11 0.55 RR42_RS20070 glycine dehydrogenase 0.45 RR42_RS20060 glycine cleavage system protein T low > 128
Rhodanobacter sp. FW510-T8 0.55 OKGIIK_06740 gcvP2 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain 0.53 OKGIIK_01305 gcvT glycine cleavage system aminomethyltransferase GcvT low > 52
Lysobacter sp. OAE881 0.55 ABIE51_RS14345 aminomethyl-transferring glycine dehydrogenase 0.54 ABIE51_RS16365 glycine cleavage system aminomethyltransferase GcvT 0.86 1
Ralstonia solanacearum UW163 0.55 UW163_RS04950 glycine dehydrogenase (aminomethyl-transferring) 0.47 UW163_RS04960 glycine cleavage system protein T — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS08660 glycine dehydrogenase (aminomethyl-transferring) 0.47 RALBFv3_RS08650 glycine cleavage system protein T 0.77 44
Ralstonia solanacearum PSI07 0.55 RPSI07_RS08575 glycine dehydrogenase (aminomethyl-transferring) 0.47 RPSI07_RS08585 glycine cleavage system protein T low > 81
Ralstonia solanacearum GMI1000 0.54 RS_RS16510 glycine dehydrogenase 0.47 RS_RS16500 aminomethyltransferase 0.52 58
Rhizobium sp. OAE497 0.54 ABIE40_RS09950 aminomethyl-transferring glycine dehydrogenase 0.23 ABIE40_RS09940 glycine cleavage system aminomethyltransferase GcvT 0.95 1
Ralstonia sp. UNC404CL21Col 0.54 ABZR87_RS03935 aminomethyl-transferring glycine dehydrogenase 0.47 ABZR87_RS03925 glycine cleavage system aminomethyltransferase GcvT 0.77 2
Sinorhizobium meliloti 1021 0.54 SMc02049 glycine dehydrogenase 0.23 SMc02047 glycine cleavage system aminomethyltransferase T 0.95 1
Xanthomonas campestris pv. campestris strain 8004 0.54 Xcc-8004.3878.1 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.53 Xcc-8004.1567.1 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) 0.52 3
Castellaniella sp019104865 MT123 0.54 ABCV34_RS08835 aminomethyl-transferring glycine dehydrogenase 0.50 ABCV34_RS08845 glycine cleavage system aminomethyltransferase GcvT 0.90 40
Variovorax sp. SCN45 0.54 GFF6478 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.21 GFF6476 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) low > 127
Mucilaginibacter yixingensis YX-36 DSM 26809 0.53 ABZR88_RS01785 aminomethyl-transferring glycine dehydrogenase 0.29 ABZR88_RS21210 glycine cleavage system aminomethyltransferase GcvT — —
Phaeobacter inhibens DSM 17395 0.53 PGA1_78p00310 glycine dehydrogenase 0.25 PGA1_78p00290 aminomethyltransferase GcvT — —
Synechococcus elongatus PCC 7942 0.53 Synpcc7942_2047 gcvP glycine dehydrogenase 0.34 Synpcc7942_2308 gcvT glycine cleavage system aminomethyltransferase T 0.92 3
Dinoroseobacter shibae DFL-12 0.53 Dshi_2680 glycine dehydrogenase (RefSeq) 0.20 Dshi_2682 glycine cleavage system T protein (RefSeq) 0.72 1
Agrobacterium fabrum C58 0.53 Atu1462 glycine cleavage system protein P2 0.22 Atu1464 glycine cleavage system T protein, aminomethyltransferase 0.97 1
Acidovorax sp. GW101-3H11 0.52 Ac3H11_167 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.21 Ac3H11_165 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) 0.41 23
Hydrogenophaga sp. GW460-11-11-14-LB1 0.52 GFF5215 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) 0.23 GFF5213 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) low > 90
Pontibacter actiniarum KMM 6156, DSM 19842 0.52 CA264_18410 glycine dehydrogenase (aminomethyl-transferring) 0.31 CA264_00210 glycine cleavage system protein T — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.52 Echvi_0744 glycine dehydrogenase (decarboxylating) 0.31 Echvi_0091 glycine cleavage system T protein 0.47 6
Pedobacter sp. GW460-11-11-14-LB5 0.51 CA265_RS25185 glycine dehydrogenase (aminomethyl-transferring) 0.30 CA265_RS23960 glycine cleavage system protein T 0.34 16
Mycobacterium tuberculosis H37Rv 0.50 Rv1832 Probable glycine dehydrogenase GcvB (glycine decarboxylase) (glycine cleavage system P-protein) 0.28 Rv2211c Probable aminomethyltransferase GcvT (glycine cleavage system T protein) — —
Bacteroides ovatus ATCC 8483 0.48 BACOVA_04038 glycine dehydrogenase 0.30 BACOVA_05378 aminomethyltransferase low > 94
Parabacteroides merdae CL09T00C40 0.47 HMPREF1078_RS15115 aminomethyl-transferring glycine dehydrogenase 0.27 HMPREF1078_RS10420 glycine cleavage system aminomethyltransferase GcvT 0.62 46
Bacteroides stercoris CC31F 0.47 HMPREF1181_RS16815 aminomethyl-transferring glycine dehydrogenase 0.29 HMPREF1181_RS13255 glycine cleavage system aminomethyltransferase GcvT 0.80 3
Bacteroides thetaiotaomicron VPI-5482 0.47 BT1147 glycine dehydrogenase [decarboxylating] (NCBI ptt file) 0.30 BT4584 putative aminomethyltransferase (NCBI ptt file) 0.28 35
Phocaeicola dorei CL03T12C01 0.46 ABI39_RS15100 aminomethyl-transferring glycine dehydrogenase 0.28 ABI39_RS18950 glycine cleavage system aminomethyltransferase GcvT low > 72
Phocaeicola vulgatus CL09T03C04 0.46 HMPREF1058_RS18780 aminomethyl-transferring glycine dehydrogenase 0.28 HMPREF1058_RS04685 glycine cleavage system aminomethyltransferase GcvT 0.81 6

Not shown: 2 genomes with orthologs for ECD_02735 only; 11 genomes with orthologs for ECD_02737 only