Conservation of cofitness between ECD_00435 and ECD_02482 in Escherichia coli BL21

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_00435 copper transporter 1.0 ECD_02482 protein disaggregation chaperone 0.71 14
Escherichia coli BW25113 1.00 b0484 copA copper transporter (NCBI) 1.00 b2592 clpB protein disaggregation chaperone (NCBI) low > 76
Escherichia coli ECOR27 1.00 NOLOHH_01015 copA copper-exporting P-type ATPase CopA 1.00 NOLOHH_12940 clpB ATP-dependent chaperone ClpB low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_03190 Copper-exporting P-type ATPase 1.00 OHPLBJKB_01114 Chaperone protein ClpB low > 73
Escherichia coli ECOR38 0.99 HEPCGN_06710 copA copper-exporting P-type ATPase CopA 1.00 HEPCGN_20390 clpB ATP-dependent chaperone ClpB low > 87
Escherichia coli ECRC62 0.99 BNILDI_22435 copA copper-exporting P-type ATPase CopA 1.00 BNILDI_11745 clpB ATP-dependent chaperone ClpB low > 75
Escherichia coli ECRC100 0.99 OKFHMN_08075 copA copper-exporting P-type ATPase CopA 1.00 OKFHMN_21265 clpB ATP-dependent chaperone ClpB low > 80
Escherichia coli ECRC99 0.99 KEDOAH_19895 copA copper-exporting P-type ATPase CopA 1.00 KEDOAH_06955 clpB ATP-dependent chaperone ClpB
Escherichia coli ECRC98 0.99 JDDGAC_11720 copA copper-exporting P-type ATPase CopA 1.00 JDDGAC_24930 clpB ATP-dependent chaperone ClpB low > 86
Escherichia coli ECRC101 0.99 MCAODC_27295 copA copper-exporting P-type ATPase CopA 1.00 MCAODC_11795 clpB ATP-dependent chaperone ClpB low > 87
Escherichia coli ECRC102 0.99 NIAGMN_06125 copA copper-exporting P-type ATPase CopA 1.00 NIAGMN_19035 clpB ATP-dependent chaperone ClpB
Escherichia fergusonii Becca 0.99 EFB2_03575 Copper-exporting P-type ATPase 1.00 EFB2_01298 Chaperone protein ClpB low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS02865 copper-exporting P-type ATPase CopA 1.00 ECOLIN_RS14665 ATP-dependent chaperone ClpB
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF4404 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.97 GFF4184 ClpB protein 0.58 18
Enterobacter asburiae PDN3 0.89 EX28DRAFT_2474 copper-(or silver)-translocating P-type ATPase 0.97 EX28DRAFT_2693 ATP-dependent chaperone ClpB low > 76
Klebsiella michiganensis M5al 0.88 BWI76_RS06905 Cu+ exporting ATPase 0.95 BWI76_RS21440 ATP-dependent chaperone ClpB low > 92
Enterobacter sp. TBS_079 0.87 MPMX20_01084 Copper-exporting P-type ATPase 0.97 MPMX20_03461 Chaperone protein ClpB low > 85
Serratia liquefaciens MT49 0.74 IAI46_05310 copper-exporting P-type ATPase CopA 0.87 IAI46_03995 ATP-dependent chaperone ClpB low > 86
Pectobacterium carotovorum WPP14 0.72 HER17_RS15625 copper-exporting P-type ATPase CopA 0.88 HER17_RS05410 ATP-dependent chaperone ClpB low > 75
Dickeya dianthicola ME23 0.71 DZA65_RS06225 copper-exporting P-type ATPase CopA 0.88 DZA65_RS17320 ATP-dependent chaperone ClpB low > 75
Dickeya dianthicola 67-19 0.70 HGI48_RS05890 copper-exporting P-type ATPase CopA 0.89 HGI48_RS16225 ATP-dependent chaperone ClpB low > 71
Dickeya dadantii 3937 0.70 DDA3937_RS05845 copper-exporting P-type ATPase CopA 0.88 DDA3937_RS16100 ATP-dependent chaperone ClpB low > 74
Rahnella sp. WP5 0.67 EX31_RS22575 copper-exporting P-type ATPase CopA 0.87 EX31_RS07560 ATP-dependent chaperone ClpB low > 89
Pantoea sp. MT58 0.67 IAI47_14400 copper-exporting P-type ATPase CopA 0.89 IAI47_04435 ATP-dependent chaperone ClpB low > 76
Erwinia tracheiphila SCR3 0.66 LU632_RS15300 copA copper-exporting P-type ATPase CopA 0.89 LU632_RS16935 clpB ATP-dependent chaperone ClpB low > 74
Kangiella aquimarina DSM 16071 0.48 B158DRAFT_1616 copper-(or silver)-translocating P-type ATPase 0.73 B158DRAFT_2535 ATP-dependent chaperone ClpB low > 40
Vibrio cholerae E7946 ATCC 55056 0.47 CSW01_11300 copper-exporting P-type ATPase A 0.78 CSW01_03705 chaperone protein ClpB low > 62
Marinobacter adhaerens HP15 0.46 HP15_3546 copper-translocating P-type ATPase 0.74 HP15_529 protein disaggregation chaperone low > 73
Alteromonas macleodii MIT1002 0.46 MIT1002_00284 Copper-exporting P-type ATPase A 0.77 MIT1002_02677 Heat shock protein F84.1 low > 70
Shewanella sp. ANA-3 0.45 Shewana3_4145 copper-translocating P-type ATPase (RefSeq) 0.79 Shewana3_3169 ATPase (RefSeq) low > 73
Shewanella loihica PV-4 0.43 Shew_3818 copper-translocating P-type ATPase (RefSeq) 0.79 Shew_2948 ATPase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.42 SO1689 cation transport ATPase, E1-E2 family (NCBI ptt file) 0.79 SO3577 clpB clpB protein (NCBI ptt file) low > 76
Acinetobacter radioresistens SK82 0.37 MPMX26_01948 Copper-transporting P-type ATPase 0.65 MPMX26_01096 Chaperone protein ClpB low > 36
Agrobacterium fabrum C58 0.37 Atu1195 heavy-metal transporting P-type ATPase 0.58 Atu4177 ATP-dependent Clp protease, ATP-binding subunit low > 89
Dinoroseobacter shibae DFL-12 0.36 Dshi_4065 heavy metal translocating P-type ATPase (RefSeq) 0.57 Dshi_0617 ATPase AAA-2 domain protein (RefSeq)
Sinorhizobium meliloti 1021 0.34 SM_b21578 copper-transporting P-type ATPase 0.57 SMc02433 ATP-dependent protease low > 103
Castellaniella sp019104865 MT123 0.34 ABCV34_RS04200 heavy metal translocating P-type ATPase 0.62 ABCV34_RS06205 ATP-dependent chaperone ClpB low > 48
Bosea sp. OAE506 0.34 ABIE41_RS14220 heavy metal translocating P-type ATPase 0.58 ABIE41_RS23785 ATP-dependent chaperone ClpB low > 77
Sphingomonas koreensis DSMZ 15582 0.34 Ga0059261_0422 copper-(or silver)-translocating P-type ATPase/heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase 0.59 Ga0059261_1434 ATP-dependent chaperone ClpB low > 68
Pontibacter actiniarum KMM 6156, DSM 19842 0.34 CA264_02930 copper-translocating P-type ATPase 0.52 CA264_14135 ATP-dependent chaperone ClpB low > 74
Bacteroides stercoris CC31F 0.34 HMPREF1181_RS09430 heavy metal translocating P-type ATPase 0.54 HMPREF1181_RS11960 ATP-dependent chaperone ClpB low > 56
Fusobacterium nucleatum SB010 0.34 HUW76_08385 copper-translocating P-type ATPase 0.51 HUW76_09935 ATP-dependent chaperone ClpB low > 35
Synechococcus elongatus PCC 7942 0.33 Synpcc7942_1570 pacS Heavy metal translocating P-type ATPase 0.56 Synpcc7942_1089 clpB ATPase low > 38
Phaeobacter inhibens DSM 17395 0.33 PGA1_c02520 copper-transporting P-type ATPase ActP 0.56 PGA1_c32440 chaperone protein ClpB low > 62
Echinicola vietnamensis KMM 6221, DSM 17526 0.33 Echvi_4125 copper-(or silver)-translocating P-type ATPase 0.50 Echvi_0754 ATP-dependent chaperone ClpB low > 79
Pseudomonas sp. S08-1 0.33 OH686_07395 copper-translocating P-type ATPase 0.70 OH686_16420 ATP-dependent chaperone protein ClpB low > 80
Azospirillum sp. SherDot2 0.32 MPMX19_06430 Copper-exporting P-type ATPase 0.59 MPMX19_02442 Chaperone protein ClpB low > 112
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU2324 copper-translocating P-type ATPase (TIGR) 0.54 DVU1874 clpB ATP-dependent Clp protease, ATP-binding subunit ClpB (TIGR) low > 55
Acidovorax sp. GW101-3H11 0.32 Ac3H11_4218 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.65 Ac3H11_1474 ClpB protein low > 79
Pseudomonas fluorescens FW300-N2E3 0.31 AO353_06155 copper-transporting ATPase 0.70 AO353_14230 ATP-dependent chaperone ClpB low > 101
Pseudomonas fluorescens FW300-N2E2 0.31 Pf6N2E2_3487 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.70 Pf6N2E2_5129 ClpB protein low > 103
Pseudomonas stutzeri RCH2 0.31 Psest_0738 copper-(or silver)-translocating P-type ATPase 0.71 Psest_0711 ATP-dependent chaperone ClpB low > 67
Pseudomonas putida KT2440 0.31 PP_0586 cadmium translocating P-type ATPase 0.69 PP_0625 Chaperone protein ClpB low > 96
Bacteroides ovatus ATCC 8483 0.31 BACOVA_04047 copper-exporting ATPase 0.54 BACOVA_05393 ATP-dependent chaperone protein ClpB low > 94
Pseudomonas fluorescens GW456-L13 0.31 PfGW456L13_24 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.70 PfGW456L13_1495 ClpB protein low > 87
Dechlorosoma suillum PS 0.31 Dsui_1650 copper/silver-translocating P-type ATPase 0.67 Dsui_2161 ATP-dependent chaperone ClpB low > 51
Shewanella amazonensis SB2B 0.31 Sama_1786 copper-translocating P-type ATPase (RefSeq) 0.80 Sama_2603 clpB protein (RefSeq) low > 62
Pseudomonas sp. RS175 0.31 PFR28_05244 Copper-exporting P-type ATPase 0.70 PFR28_03746 Chaperone protein ClpB low > 88
Bacteroides thetaiotaomicron VPI-5482 0.31 BT1091 cation-transporting ATPase pacS (NCBI ptt file) 0.54 BT4597 endopeptidase Clp ATP-binding chain B (NCBI ptt file) low > 81
Desulfovibrio vulgaris Miyazaki F 0.31 DvMF_3170 heavy metal translocating P-type ATPase (RefSeq) 0.54 DvMF_0567 ATP-dependent chaperone ClpB (RefSeq) low > 51
Pseudomonas fluorescens FW300-N2C3 0.31 AO356_08065 copper-transporting ATPase 0.70 AO356_15935 ATP-dependent chaperone ClpB low > 104
Paraburkholderia sabiae LMG 24235 0.31 QEN71_RS17330 heavy metal translocating P-type ATPase 0.68 QEN71_RS22370 ATP-dependent chaperone ClpB low > 153
Pseudomonas fluorescens FW300-N1B4 0.31 Pf1N1B4_1262 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) 0.70 Pf1N1B4_2824 ClpB protein low > 87
Parabacteroides merdae CL09T00C40 0.30 HMPREF1078_RS01895 heavy metal translocating P-type ATPase 0.52 HMPREF1078_RS00500 ATP-dependent chaperone ClpB low > 61
Ralstonia sp. UNC404CL21Col 0.30 ABZR87_RS04235 heavy metal translocating P-type ATPase 0.66 ABZR87_RS11485 ATP-dependent chaperone ClpB low > 80
Lysobacter sp. OAE881 0.30 ABIE51_RS09555 heavy metal translocating P-type ATPase 0.74 ABIE51_RS04925 ATP-dependent chaperone ClpB low > 62
Phocaeicola dorei CL03T12C01 0.30 ABI39_RS15120 copper-translocating P-type ATPase 0.52 ABI39_RS18885 ATP-dependent chaperone ClpB low > 72
Phocaeicola vulgatus CL09T03C04 0.30 HMPREF1058_RS18800 copper-translocating P-type ATPase 0.52 HMPREF1058_RS04980 ATP-dependent chaperone ClpB low > 67
Pseudomonas syringae pv. syringae B728a ΔmexB 0.30 Psyr_0654 Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase 0.69 Psyr_0728 AAA ATPase, central region:Clp, N terminal:Clp, N terminal low > 86
Pseudomonas syringae pv. syringae B728a 0.30 Psyr_0654 Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase 0.69 Psyr_0728 AAA ATPase, central region:Clp, N terminal:Clp, N terminal low > 86
Pseudomonas simiae WCS417 0.30 PS417_03160 metal ABC transporter ATPase 0.70 PS417_03830 protein disaggregation chaperone low > 88
Burkholderia phytofirmans PsJN 0.30 BPHYT_RS34125 heavy metal translocating P-type ATPase 0.68 BPHYT_RS08990 protein disaggregation chaperone low > 109
Ralstonia solanacearum GMI1000 0.29 RS_RS16775 copper-translocating P-type ATPase 0.66 RS_RS06695 chaperone protein ClpB low > 80
Pseudomonas fluorescens SBW25 0.29 PFLU_RS03240 copper-translocating P-type ATPase 0.70 PFLU_RS03880 ATP-dependent chaperone ClpB low > 109
Pseudomonas fluorescens SBW25-INTG 0.29 PFLU_RS03240 copper-translocating P-type ATPase 0.70 PFLU_RS03880 ATP-dependent chaperone ClpB low > 109
Ralstonia solanacearum PSI07 0.29 RPSI07_RS08310 copper-translocating P-type ATPase 0.66 RPSI07_RS17450 ATP-dependent chaperone ClpB low > 81
Paraburkholderia bryophila 376MFSha3.1 0.29 H281DRAFT_03512 Cu+-exporting ATPase 0.68 H281DRAFT_00817 ATP-dependent Clp protease ATP-binding subunit ClpB low > 103
Magnetospirillum magneticum AMB-1 0.29 AMB_RS09145 copper-translocating P-type ATPase 0.57 AMB_RS07865 ATP-dependent chaperone ClpB
Herbaspirillum seropedicae SmR1 0.28 HSERO_RS08020 heavy metal translocating P-type ATPase 0.66 HSERO_RS10545 protein disaggregation chaperone 0.45 11
Paraburkholderia graminis OAS925 0.28 ABIE53_004745 Cu+-exporting ATPase 0.68 ABIE53_002033 ATP-dependent Clp protease ATP-binding subunit ClpB low > 113
Rhodospirillum rubrum S1H 0.27 Rru_A1894 heavy metal translocating P-type ATPase (NCBI) 0.58 Rru_A0753 Chaperone clpB (NCBI) low > 58
Variovorax sp. OAS795 0.25 ABID97_RS02825 heavy metal translocating P-type ATPase 0.63 ABID97_RS10930 ATP-dependent chaperone ClpB low > 91
Mucilaginibacter yixingensis YX-36 DSM 26809 0.22 ABZR88_RS09650 cation-translocating P-type ATPase 0.52 ABZR88_RS10630 ATP-dependent chaperone ClpB low > 71
Caulobacter crescentus NA1000 Δfur 0.18 CCNA_01473 E1-E2 cation pump ATPase fixI 0.57 CCNA_00922 ClpB protein low > 67
Caulobacter crescentus NA1000 0.18 CCNA_01473 E1-E2 cation pump ATPase fixI 0.57 CCNA_00922 ClpB protein 0.39 29
Azospirillum brasilense Sp245 0.17 AZOBR_RS01150 ATPase P 0.59 AZOBR_RS18950 ATPase AAA

Not shown: 2 genomes with orthologs for ECD_00435 only; 16 genomes with orthologs for ECD_02482 only