| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_13865 | | nitrogen regulation protein NR(I) | 1.0 | CSW01_13695 | | two-component system response regulator OmpR | 0.50 | 3 |
| Enterobacter asburiae PDN3 | 0.73 | EX28DRAFT_4350 | | nitrogen regulation protein NR(I) | 0.85 | EX28DRAFT_4138 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | low | > 76 |
| Enterobacter sp. TBS_079 | 0.73 | MPMX20_04597 | | DNA-binding transcriptional regulator NtrC | 0.85 | MPMX20_04292 | | Transcriptional regulatory protein OmpR | low | > 85 |
| Serratia liquefaciens MT49 | 0.72 | IAI46_24960 | | nitrogen regulation protein NR(I) | 0.86 | IAI46_23790 | | two-component system response regulator OmpR | low | > 87 |
| Escherichia fergusonii Becca | 0.72 | EFB2_04748 | | DNA-binding transcriptional regulator NtrC | 0.85 | EFB2_00423 | | Transcriptional regulatory protein OmpR | low | > 86 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.72 | GFF2220 | | Nitrogen regulation protein NR(I) | 0.85 | GFF613 | | Two-component system response regulator OmpR | low | > 78 |
| Escherichia coli ECRC101 | 0.72 | MCAODC_04610 | glnG | nitrogen regulation protein NR(I) | 0.85 | MCAODC_07565 | ompR_G63V | two-component system response regulator OmpR | low | > 87 |
| Escherichia coli ECRC102 | 0.72 | NIAGMN_11865 | glnG | nitrogen regulation protein NR(I) | 0.85 | NIAGMN_14805 | ompR_G63V | two-component system response regulator OmpR | low | > 80 |
| Escherichia coli ECRC99 | 0.72 | KEDOAH_14040 | glnG | nitrogen regulation protein NR(I) | 0.85 | KEDOAH_11105 | ompR_G63V | two-component system response regulator OmpR | — | — |
| Escherichia coli ECRC98 | 0.72 | JDDGAC_17735 | glnG | nitrogen regulation protein NR(I) | 0.85 | JDDGAC_20665 | ompR_G63V | two-component system response regulator OmpR | — | — |
| Escherichia coli ECOR27 | 0.72 | NOLOHH_06240 | glnG | nitrogen regulation protein NR(I) | 0.85 | NOLOHH_08825 | ompR_G63V | two-component system response regulator OmpR | low | > 75 |
| Escherichia coli BW25113 | 0.72 | b3868 | glnG | fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) | 0.85 | b3405 | ompR | osmolarity response regulator (NCBI) | low | > 76 |
| Escherichia coli ECRC100 | 0.72 | OKFHMN_14110 | glnG | nitrogen regulation protein NR(I) | 0.85 | OKFHMN_17035 | ompR_G63V | two-component system response regulator OmpR | low | > 79 |
| Escherichia coli Nissle 1917 | 0.72 | ECOLIN_RS22295 | | nitrogen regulation protein NR(I) | 0.85 | ECOLIN_RS19455 | | two-component system response regulator OmpR | low | > 55 |
| Klebsiella pneumoniae MKP103 | 0.72 | KDGMDA_09000 | | nitrogen regulation protein NR(I) | 0.85 | KDGMDA_06980 | | two-component system response regulator OmpR | 0.26 | 78 |
| Escherichia coli ECRC62 | 0.72 | BNILDI_05290 | glnG | nitrogen regulation protein NR(I) | 0.85 | BNILDI_02695 | ompR_G63V | two-component system response regulator OmpR | low | > 75 |
| Escherichia coli ECOR38 | 0.72 | HEPCGN_12740 | glnG | nitrogen regulation protein NR(I) | 0.85 | HEPCGN_15845 | ompR_G63V | two-component system response regulator OmpR | low | > 88 |
| Escherichia coli BL21 | 0.72 | ECD_03753 | | fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein | 0.85 | ECD_03257 | | response regulator in two-component regulatory system with EnvZ | low | > 61 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.72 | OHPLBJKB_04184 | | DNA-binding transcriptional regulator NtrC | 0.85 | OHPLBJKB_00298 | | Transcriptional regulatory protein OmpR | low | > 74 |
| Klebsiella michiganensis M5al | 0.72 | BWI76_RS00385 | | nitrogen assimilation regulatory protein | 0.85 | BWI76_RS26665 | | DNA-binding response regulator | low | > 92 |
| Klebsiella pneumoniae MRSN742743 | 0.72 | GJGHJB_04967 | glnG | nitrogen regulation protein NR(I) | 0.85 | GJGHJB_00340 | ompR | two-component system response regulator OmpR | 0.37 | 6 |
| Pantoea sp. MT58 | 0.72 | IAI47_00450 | | nitrogen regulation protein NR(I) | 0.85 | IAI47_01820 | | two-component system response regulator OmpR | low | > 76 |
| Rahnella sp. WP5 | 0.72 | EX31_RS15880 | | nitrogen regulation protein NR(I) | 0.86 | EX31_RS04800 | | two-component system response regulator OmpR | low | > 89 |
| Erwinia amylovora T8 | 0.72 | OLJFJH_05495 | | nitrogen regulation protein NR(I) | 0.85 | OLJFJH_04160 | | two-component system response regulator OmpR | low | > 58 |
| Pantoea agglomerans CFBP13505 P0401 | 0.71 | PagCFBP13516_RS00435 | glnG | nitrogen regulation protein NR(I) | 0.85 | PagCFBP13516_RS01815 | ompR | osmolarity response regulator transcription factor OmpR | low | > 80 |
| Pectobacterium carotovorum WPP14 | 0.71 | HER17_RS21440 | | nitrogen regulation protein NR(I) | 0.85 | HER17_RS01700 | | two-component system response regulator OmpR | 0.89 | 19 |
| Dickeya dianthicola ME23 | 0.71 | DZA65_RS22210 | | nitrogen regulation protein NR(I) | 0.85 | DZA65_RS20840 | | two-component system response regulator OmpR | low | > 75 |
| Dickeya dianthicola 67-19 | 0.71 | HGI48_RS21235 | | nitrogen regulation protein NR(I) | 0.85 | HGI48_RS19750 | | two-component system response regulator OmpR | low | > 71 |
| Dickeya dadantii 3937 | 0.71 | DDA3937_RS00125 | | nitrogen regulation protein NR(I) | 0.85 | DDA3937_RS19620 | | two-component system response regulator OmpR | low | > 74 |
| Erwinia tracheiphila SCR3 | 0.71 | LU632_RS22135 | glnG | nitrogen regulation protein NR(I) | 0.85 | LU632_RS22940 | ompR | two-component system response regulator OmpR | low | > 73 |
| Erwinia tracheiphila HP pepo 2.2 | 0.70 | IJEDHG_08285 | glnG | nitrogen regulation protein NR(I) | 0.85 | IJEDHG_11955 | ompR_G63V | two-component system response regulator OmpR | low | > 61 |
| Shewanella oneidensis MR-1 | 0.69 | SO4472 | ntrC | nitrogen regulation protein NR(I) (NCBI ptt file) | 0.80 | SO4633 | ompR | transcriptional regulatory protein OmpR (NCBI ptt file) | low | > 76 |
| Shewanella amazonensis SB2B | 0.69 | Sama_3427 | | response regulator receiver protein (RefSeq) | 0.80 | Sama_3510 | ompR | osmolarity response regulator (RefSeq) | low | > 62 |
| Shewanella sp. ANA-3 | 0.69 | Shewana3_0258 | | nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) | 0.80 | Shewana3_4017 | ompR | osmolarity response regulator (RefSeq) | low | > 73 |
| Shewanella loihica PV-4 | 0.69 | Shew_3561 | | nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) | 0.81 | Shew_3637 | ompR | osmolarity response regulator (RefSeq) | low | > 60 |
| Alteromonas macleodii MIT1002 | 0.69 | MIT1002_03186 | | Nitrogen regulation protein NR(I) | 0.79 | MIT1002_03968 | | Transcriptional regulatory protein OmpR | low | > 70 |
| Pseudomonas fluorescens FW300-N2E3 | 0.67 | AO353_12145 | | nitrogen regulation protein NR(I) | 0.72 | AO353_11745 | | chemotaxis protein CheY | — | — |
| Pseudomonas fluorescens SBW25 | 0.66 | PFLU_RS01685 | | nitrogen regulation protein NR(I) | 0.71 | PFLU_RS01280 | | two-component system response regulator OmpR | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.66 | AO356_09730 | | nitrogen regulation protein NR(I) | 0.72 | AO356_10170 | | chemotaxis protein CheY | low | > 104 |
| Pseudomonas fluorescens FW300-N1B4 | 0.66 | Pf1N1B4_1611 | | Nitrogen regulation protein NR(I) | 0.72 | Pf1N1B4_1772 | | Two-component system response regulator OmpR | — | — |
| Pseudomonas segetis P6 | 0.66 | ACVTMO_RS21260 | ntrC | nitrogen regulation protein NR(I) | 0.74 | ACVTMO_RS03820 | ompR | osmolarity response regulator transcription factor OmpR | low | > 75 |
| Pseudomonas simiae WCS417 | 0.66 | PS417_01635 | | nitrogen regulation protein NR(I) | 0.71 | PS417_01170 | | chemotaxis protein CheY | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.66 | PFLU_RS01685 | | nitrogen regulation protein NR(I) | 0.71 | PFLU_RS01280 | | two-component system response regulator OmpR | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.66 | PfGW456L13_347 | | Nitrogen regulation protein NR(I) | 0.72 | PfGW456L13_427 | | Two-component system response regulator OmpR | low | > 87 |
| Pseudomonas lactucae CFBP13502 | 0.66 | GEMAOFIL_00547 | | DNA-binding transcriptional regulator NtrC | 0.71 | GEMAOFIL_00461 | | Transcriptional regulatory protein OmpR | — | — |
| Pseudomonas putida KT2440 | 0.66 | PP_5048 | | two-component system DNA-binding transcriptional dual regulator GlnL/GlnG | 0.71 | PP_0246 | | two-component system DNA-binding response transcriptional dual regulator | low | > 96 |
| Pseudomonas sp. FW215-L2 | 0.66 | GFF547 | | Nitrogen regulation protein NR(I) | 0.72 | GFF6518 | | Transcriptional regulatory protein OmpR | — | — |
| Pseudomonas protegens RBAN4 | 0.66 | FABNJH_01975 | ntrC | nitrogen regulation protein NR(I) | 0.71 | FABNJH_01440 | ompR | two-component system response regulator OmpR | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.66 | Pf6N2E2_3826 | | Nitrogen regulation protein NR(I) | 0.72 | Pf6N2E2_3905 | | Two-component system response regulator OmpR | — | — |
| Pseudomonas sp. DMC3 | 0.66 | GFF4081 | | DNA-binding transcriptional regulator NtrC | 0.72 | GFF4183 | | Transcriptional regulatory protein OmpR | low | > 89 |
| Pseudomonas sp. BP01 | 0.66 | JOY50_RS09450 | ntrC | nitrogen regulation protein NR(I) | 0.71 | JOY50_RS18350 | ompR | two-component system response regulator OmpR | low | > 84 |
| Pseudomonas orientalis W4I3 | 0.66 | QF045_RS04705 | | nitrogen regulation protein NR(I) | 0.72 | QF045_RS04300 | | two-component system response regulator OmpR | low | > 93 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.66 | Psyr_4822 | | Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) | 0.72 | Psyr_0258 | | Two-component response regulator OmpR | — | — |
| Pseudomonas sp. SVBP6 | 0.66 | COO64_RS13325 | ntrC | nitrogen regulation protein NR(I) | 0.72 | COO64_RS00700 | ompR | two-component system response regulator OmpR | low | > 91 |
| Pseudomonas syringae pv. syringae B728a | 0.66 | Psyr_4822 | | Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) | 0.72 | Psyr_0258 | | Two-component response regulator OmpR | — | — |
| Pseudomonas sp. S08-1 | 0.66 | OH686_10640 | | nitrogen regulation protein NR(I) | 0.73 | OH686_11095 | | Two-component system response regulator OmpR | low | > 80 |
| Pseudomonas sp. RS175 | 0.66 | PFR28_04944 | | DNA-binding transcriptional regulator NtrC | 0.72 | PFR28_04868 | | Transcriptional regulatory protein OmpR | low | > 88 |
| Pseudomonas aeruginosa PUPa3 | 0.66 | NPBIFN_05441 | ntrC | two-component system response regulator NtrC | 0.70 | NPBIFN_05524 | amgR | two-component system response regulator AmgR | — | — |
| Pseudomonas aeruginosa MRSN321 | 0.66 | PFGADD_05364 | ntrC | two-component system response regulator NtrC | 0.70 | PFGADD_05448 | amgR | two-component system response regulator AmgR | — | — |
| Pseudomonas aeruginosa PA14 | 0.66 | IKLFDK_27895 | | two-component system response regulator NtrC | 0.70 | IKLFDK_27475 | | two-component system response regulator AmgR | low | > 98 |
| Pseudomonas stutzeri RCH2 | 0.65 | Psest_3932 | | nitrogen regulation protein NR(I) | 0.70 | Psest_3995 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | low | > 67 |
| Marinobacter adhaerens HP15 | 0.65 | HP15_425 | | two-component response regulator NtrC | 0.41 | HP15_3961 | | two-component transcriptional regulator, winged helix family | low | > 73 |
| Acinetobacter radioresistens SK82 | 0.65 | MPMX26_01292 | | DNA-binding transcriptional regulator NtrC | 0.67 | MPMX26_02838 | | Transcriptional regulatory protein OmpR | low | > 36 |
| Acinetobacter baumannii LAC-4 | 0.64 | RR41_RS08030 | | nitrogen regulation protein NR(I) | 0.67 | RR41_RS01390 | | two-component system response regulator OmpR | — | — |
| Methylophilus sp. DMC18 | 0.60 | GFF2024 | | DNA-binding transcriptional regulator NtrC | 0.64 | GFF2713 | | Transcriptional regulatory protein OmpR | — | — |
| Herbaspirillum seropedicae SmR1 | 0.57 | HSERO_RS15680 | | chemotaxis protein CheY | 0.59 | HSERO_RS10760 | | chemotaxis protein CheY | — | — |
| Collimonas humicola GW821-FHT01A05 | 0.56 | MPMX01_04104 | | DNA-binding transcriptional regulator NtrC | 0.61 | MPMX01_02837 | | Transcriptional regulatory protein OmpR | low | > 87 |
| Dechlorosoma suillum PS | 0.56 | Dsui_1051 | | nitrogen regulation protein NR(I) | 0.61 | Dsui_2401 | | response regulator with CheY-like receiver domain and winged-helix DNA-binding domain | low | > 51 |
| Ralstonia solanacearum GMI1000 | 0.56 | RS_RS06320 | | nitrogen regulation protein NR(I) | 0.60 | RS_RS08305 | | two-component system response regulator OmpR | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.55 | RALBFv3_RS15540 | | nitrogen regulation protein NR(I) | 0.60 | RALBFv3_RS01415 | | two-component system response regulator OmpR | — | — |
| Ralstonia solanacearum UW163 | 0.55 | UW163_RS13000 | | nitrogen regulation protein NR(I) | 0.60 | UW163_RS14725 | | two-component system response regulator OmpR | — | — |
| Ralstonia sp. UNC404CL21Col | 0.55 | ABZR87_RS11070 | | nitrogen regulation protein NR(I) | 0.59 | ABZR87_RS13210 | | two-component system response regulator OmpR | low | > 80 |
| Ralstonia solanacearum PSI07 | 0.55 | RPSI07_RS17815 | | nitrogen regulation protein NR(I) | 0.60 | RPSI07_RS16070 | | two-component system response regulator OmpR | low | > 81 |
| Cupriavidus basilensis FW507-4G11 | 0.54 | RR42_RS12980 | | chemotaxis protein CheY | 0.60 | RR42_RS07885 | | chemotaxis protein CheY | low | > 128 |
| Paraburkholderia sabiae LMG 24235 | 0.54 | QEN71_RS05675 | | nitrogen regulation protein NR(I) | 0.61 | QEN71_RS22030 | | two-component system response regulator OmpR | low | > 153 |
| Variovorax sp. SCN45 | 0.54 | GFF3066 | | Nitrogen regulation protein NR(I), GlnG (=NtrC) | 0.63 | GFF408 | | Two-component system response regulator OmpR | — | — |
| Variovorax sp. OAS795 | 0.54 | ABID97_RS09945 | | nitrogen regulation protein NR(I) | 0.63 | ABID97_RS17265 | | two-component system response regulator OmpR | low | > 91 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.53 | GFF5269 | | Nitrogen regulation protein NR(I) | 0.61 | GFF4930 | | Two-component system response regulator OmpR | low | > 92 |
| Burkholderia phytofirmans PsJN | 0.53 | BPHYT_RS12935 | | chemotaxis protein CheY | 0.62 | BPHYT_RS09315 | | chemotaxis protein CheY | low | > 109 |
| Paraburkholderia graminis OAS925 | 0.53 | ABIE53_002804 | | two-component system nitrogen regulation response regulator GlnG | 0.62 | ABIE53_002101 | | two-component system phosphate regulon response regulator OmpR | low | > 113 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.53 | H281DRAFT_00454 | | nitrogen metabolism transcriptional regulator, NtrC, Fis family | 0.62 | H281DRAFT_00886 | | two component transcriptional regulator, winged helix family | low | > 103 |
| Lysobacter sp. OAE881 | 0.50 | ABIE51_RS01360 | | nitrogen regulation protein NR(I) | 0.40 | ABIE51_RS14390 | | response regulator | low | > 62 |
| Castellaniella sp019104865 MT123 | 0.49 | ABCV34_RS03540 | | nitrogen regulation protein NR(I) | 0.60 | ABCV34_RS08585 | | two-component system response regulator OmpR | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.48 | Xcc-8004.252.1 | | Nitrogen regulation protein NtrC | 0.36 | Xcc-8004.974.1 | | two-component system regulatory protein | low | > 74 |
| Dyella japonica UNC79MFTsu3.2 | 0.45 | ABZR86_RS15515 | | nitrogen regulation protein NR(I) | 0.37 | ABZR86_RS21025 | | response regulator transcription factor | low | > 74 |
| Xanthobacter sp. DMC5 | 0.41 | GFF848 | | DNA-binding transcriptional regulator NtrC | 0.41 | GFF2161 | | Transcriptional regulatory protein OmpR | — | — |
| Sinorhizobium meliloti 1021 | 0.41 | SMc01043 | | nitrogen assimilation regulatory protein | 0.41 | SM_b21561 | | two component response regulator protein | low | > 103 |
| Rhodopseudomonas palustris CGA009 | 0.40 | TX73_013420 | | nitrogen regulation protein NR(I) | 0.45 | TX73_018505 | | response regulator | low | > 86 |
| Bosea sp. OAE506 | 0.40 | ABIE41_RS16785 | | nitrogen regulation protein NR(I) | 0.46 | ABIE41_RS08395 | | response regulator | low | > 77 |
| Magnetospirillum magneticum AMB-1 | 0.40 | AMB_RS11950 | | nitrogen regulation protein NR(I) | 0.45 | AMB_RS16915 | | DNA-binding response regulator | — | — |
| Azospirillum sp. SherDot2 | 0.40 | MPMX19_01112 | | DNA-binding transcriptional regulator NtrC | 0.44 | MPMX19_00010 | | Transcriptional regulatory protein OmpR | — | — |
| Rhizobium sp. OAE497 | 0.40 | ABIE40_RS09090 | | nitrogen regulation protein NR(I) | 0.41 | ABIE40_RS24305 | | response regulator | low | > 107 |
| Azospirillum brasilense Sp245 | 0.40 | AZOBR_RS14430 | | chemotaxis protein CheY | 0.44 | AZOBR_RS00555 | | chemotaxis protein CheY | low | > 97 |
| Agrobacterium fabrum C58 | 0.39 | Atu1446 | | two component response regulator | 0.37 | Atu2206 | | two component response regulator | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.39 | Ga0059261_0137 | | nitrogen regulation protein NR(I) | 0.42 | Ga0059261_0871 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | low | > 68 |
| Sphingobium sp. HT1-2 | 0.38 | GFF1148 | | Nitrogen regulation protein NR(I), GlnG (=NtrC) | 0.41 | GFF511 | | DNA-binding response regulator | low | > 95 |
| Caulobacter crescentus NA1000 | 0.33 | CCNA_03424 | | AAA-family response regulator tacA | 0.37 | CCNA_01240 | | two-component response regulator | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.33 | CCNA_03424 | | AAA-family response regulator tacA | 0.37 | CCNA_01240 | | two-component response regulator | low | > 67 |
| Cellulophaga baltica 18 | 0.33 | M666_RS19210 | | sigma-54 dependent transcriptional regulator | 0.34 | M666_RS17080 | | response regulator transcription factor | low | > 67 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.32 | A4249_RS09115 | | sigma-54 dependent transcriptional regulator | 0.35 | A4249_RS10315 | | response regulator transcription factor | low | > 48 |
| Parabacteroides merdae CL09T00C40 | 0.32 | HMPREF1078_RS14380 | | sigma-54 dependent transcriptional regulator | 0.27 | HMPREF1078_RS04550 | | response regulator transcription factor | — | — |
| Phaeobacter inhibens DSM 17395 | 0.30 | PGA1_c14810 | | nitrogen assimilation regulatory protein NtrX | 0.40 | PGA1_c34130 | | protein PetR | — | — |
Not shown: 15 genomes with orthologs for CSW01_13865 only; 5 genomes with orthologs for CSW01_13695 only