| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_05660 | | dethiobiotin synthase | 1.0 | CSW01_12845 | | metalloprotease PmbA | 0.77 | 2 |
| Escherichia coli ECRC102 | 0.47 | NIAGMN_00330 | bioD | dethiobiotin synthase | 0.64 | NIAGMN_09775 | pmbA | metalloprotease PmbA | low | > 80 |
| Escherichia coli ECRC101 | 0.47 | MCAODC_17665 | bioD | dethiobiotin synthase | 0.64 | MCAODC_02430 | pmbA | metalloprotease PmbA | — | — |
| Escherichia coli ECRC62 | 0.47 | BNILDI_17040 | bioD | dethiobiotin synthase | 0.64 | BNILDI_07325 | pmbA | metalloprotease PmbA | low | > 75 |
| Escherichia coli BL21 | 0.47 | ECD_01562 | | putative dethiobiotin synthetase | 0.64 | ECD_04103 | | putative antibiotic peptide MccB17 maturation peptidase | low | > 61 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.47 | OHPLBJKB_02133 | | ATP-dependent dethiobiotin synthetase BioD 1 | 0.64 | OHPLBJKB_03800 | | Metalloprotease PmbA | low | > 74 |
| Escherichia coli BW25113 | 0.47 | b1593 | b1593 | orf, hypothetical protein (VIMSS) | 0.64 | b4235 | pmbA | predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) | low | > 76 |
| Escherichia coli ECRC98 | 0.47 | JDDGAC_02335 | bioD | dethiobiotin synthase | 0.64 | JDDGAC_15565 | pmbA | metalloprotease PmbA | low | > 87 |
| Escherichia coli ECRC100 | 0.47 | OKFHMN_27745 | bioD | dethiobiotin synthase | 0.64 | OKFHMN_11925 | pmbA | metalloprotease PmbA | — | — |
| Escherichia coli ECRC99 | 0.47 | KEDOAH_00360 | bioD | dethiobiotin synthase | 0.64 | KEDOAH_16230 | pmbA | metalloprotease PmbA | — | — |
| Escherichia fergusonii Becca | 0.47 | EFB2_02399 | | ATP-dependent dethiobiotin synthetase BioD 1 | 0.64 | EFB2_04298 | | Metalloprotease PmbA | low | > 86 |
| Escherichia coli Nissle 1917 | 0.47 | ECOLIN_RS08900 | | dethiobiotin synthase | 0.64 | ECOLIN_RS24570 | | metalloprotease PmbA | — | — |
| Escherichia coli ECOR27 | 0.47 | NOLOHH_18250 | bioD | dethiobiotin synthase | 0.64 | NOLOHH_04185 | pmbA | metalloprotease PmbA | — | — |
| Escherichia coli ECOR38 | 0.47 | HEPCGN_06120 | bioD | dethiobiotin synthase | 0.64 | HEPCGN_10125 | pmbA | metalloprotease PmbA | low | > 88 |
| Klebsiella pneumoniae MKP103 | 0.47 | KDGMDA_21235 | | dethiobiotin synthase | 0.63 | KDGMDA_11330 | | metalloprotease PmbA | low | > 95 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.47 | GFF1784 | | Dethiobiotin synthetase (EC 6.3.3.3) | 0.64 | GFF904 | | TldE protein, part of TldE/TldD proteolytic complex | low | > 78 |
| Pectobacterium carotovorum WPP14 | 0.47 | HER17_RS10730 | | dethiobiotin synthase | 0.66 | HER17_RS20090 | | metalloprotease PmbA | low | > 75 |
| Pantoea agglomerans CFBP13505 P0401 | 0.46 | PagCFBP13505_RS06400 | | ATP-dependent dethiobiotin synthetase BioD | 0.62 | PagCFBP13505_RS11365 | | metalloprotease PmbA | low | > 74 |
| Dickeya dianthicola 67-19 | 0.46 | HGI48_RS08690 | | ATP-dependent dethiobiotin synthetase BioD | 0.62 | HGI48_RS01415 | | metalloprotease PmbA | low | > 71 |
| Klebsiella michiganensis M5al | 0.46 | BWI76_RS15950 | | dethiobiotin synthase | 0.64 | BWI76_RS02850 | | metalloprotease PmbA | low | > 92 |
| Enterobacter sp. TBS_079 | 0.46 | MPMX20_02064 | | ATP-dependent dethiobiotin synthetase BioD 1 | 0.64 | MPMX20_00517 | | Metalloprotease PmbA | low | > 85 |
| Dickeya dianthicola ME23 | 0.46 | DZA65_RS08980 | | ATP-dependent dethiobiotin synthetase BioD | 0.62 | DZA65_RS01480 | | metalloprotease PmbA | low | > 75 |
| Dickeya dadantii 3937 | 0.45 | DDA3937_RS10680 | | ATP-dependent dethiobiotin synthetase BioD | 0.62 | DDA3937_RS01500 | | metalloprotease PmbA | low | > 74 |
| Serratia liquefaciens MT49 | 0.45 | IAI46_06540 | | ATP-dependent dethiobiotin synthetase BioD | 0.65 | IAI46_22575 | | metalloprotease PmbA | low | > 87 |
| Enterobacter asburiae PDN3 | 0.45 | EX28DRAFT_1492 | | dethiobiotin synthase | 0.64 | EX28DRAFT_3422 | | Predicted Zn-dependent proteases and their inactivated homologs | low | > 76 |
| Pantoea sp. MT58 | 0.45 | IAI47_09755 | | ATP-dependent dethiobiotin synthetase BioD | 0.62 | IAI47_02765 | | metalloprotease PmbA | low | > 76 |
| Erwinia tracheiphila HP pepo 2.2 | 0.43 | IJEDHG_23285 | bioD | dethiobiotin synthase | 0.59 | IJEDHG_06770 | pmbA | metalloprotease PmbA | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.43 | LU632_RS12300 | bioD | dethiobiotin synthase | 0.59 | LU632_RS02145 | pmbA | metalloprotease PmbA | low | > 73 |
| Erwinia amylovora T8 | 0.43 | OLJFJH_14270 | | dethiobiotin synthase | 0.63 | OLJFJH_02355 | | metalloprotease PmbA | low | > 58 |
| Rahnella sp. WP5 | 0.42 | EX31_RS23710 | | ATP-dependent dethiobiotin synthetase BioD | 0.64 | EX31_RS12320 | | metalloprotease PmbA | low | > 89 |
| Pseudomonas putida KT2440 | 0.42 | PP_0366 | | dethiobiotin synthetase | 0.49 | PP_0942 | | regulatory protease | low | > 96 |
| Pseudomonas sp. BP01 | 0.41 | JOY50_RS17950 | bioD | dethiobiotin synthase | 0.48 | JOY50_RS11080 | pmbA | metalloprotease PmbA | low | > 84 |
| Pseudomonas segetis P6 | 0.40 | MPMX49_00763 | | ATP-dependent dethiobiotin synthetase BioD 1 | 0.46 | MPMX49_03863 | | Metalloprotease PmbA | low | > 75 |
| Pseudomonas sp. SVBP6 | 0.40 | COO64_RS22705 | bioD | dethiobiotin synthase | 0.47 | COO64_RS04235 | pmbA | metalloprotease PmbA | low | > 93 |
| Pseudomonas sp. DMC3 | 0.39 | GFF72 | | ATP-dependent dethiobiotin synthetase BioD 1 | 0.47 | GFF1818 | | Metalloprotease PmbA | low | > 89 |
| Pseudomonas fluorescens GW456-L13 | 0.38 | PfGW456L13_1151 | | Dethiobiotin synthetase (EC 6.3.3.3) | 0.47 | PfGW456L13_5024 | | TldE protein, part of TldE/TldD proteolytic complex | low | > 87 |
| Shewanella oneidensis MR-1 | 0.38 | SO2737 | bioD | dethiobiotin synthase (NCBI ptt file) | 0.58 | SO4078 | pmbA | pmba protein (NCBI ptt file) | — | — |
| Shewanella sp. ANA-3 | 0.38 | Shewana3_2516 | bioD | dithiobiotin synthetase (RefSeq) | 0.58 | Shewana3_3631 | | microcin-processing peptidase 1 (RefSeq) | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.38 | PFLU_RS27630 | | dethiobiotin synthase | 0.48 | PFLU_RS04350 | | metalloprotease PmbA | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.38 | PFLU_RS27630 | | dethiobiotin synthase | 0.48 | PFLU_RS04350 | | metalloprotease PmbA | low | > 109 |
| Pseudomonas simiae WCS417 | 0.38 | PS417_25985 | | dethiobiotin synthetase | 0.47 | PS417_04295 | | peptidase PmbA | low | > 88 |
| Dyella japonica UNC79MFTsu3.2 | 0.37 | ABZR86_RS12700 | | dethiobiotin synthase | 0.45 | ABZR86_RS21700 | | metalloprotease PmbA | low | > 74 |
| Pseudomonas fluorescens FW300-N2C3 | 0.37 | AO356_14155 | | dethiobiotin synthetase | 0.48 | AO356_07085 | | peptidase PmbA | low | > 104 |
| Pseudomonas fluorescens FW300-N1B4 | 0.37 | Pf1N1B4_2491 | | Dethiobiotin synthetase (EC 6.3.3.3) | 0.47 | Pf1N1B4_1090 | | TldE protein, part of TldE/TldD proteolytic complex | low | > 87 |
| Pseudomonas orientalis W4I3 | 0.37 | QF045_RS00395 | | dethiobiotin synthase | 0.48 | QF045_RS07285 | | metalloprotease PmbA | low | > 93 |
| Pseudomonas sp. RS175 | 0.37 | PFR28_04099 | | ATP-dependent dethiobiotin synthetase BioD 1 | 0.48 | PFR28_00163 | | Metalloprotease PmbA | — | — |
| Pseudomonas lactucae CFBP13502 | 0.36 | GEMAOFIL_05318 | | ATP-dependent dethiobiotin synthetase BioD 1 | 0.48 | GEMAOFIL_01064 | | Metalloprotease PmbA | low | > 96 |
| Dechlorosoma suillum PS | 0.36 | Dsui_2884 | | dethiobiotin synthase | 0.44 | Dsui_1234 | | putative Zn-dependent protease-like protein | low | > 51 |
| Pseudomonas fluorescens FW300-N2E2 | 0.36 | Pf6N2E2_4764 | | Dethiobiotin synthetase (EC 6.3.3.3) | 0.48 | Pf6N2E2_3278 | | TldE protein, part of TldE/TldD proteolytic complex | low | > 103 |
| Pseudomonas fluorescens FW300-N2E3 | 0.36 | AO353_07505 | | dethiobiotin synthetase | 0.47 | AO353_05205 | | peptidase PmbA | low | > 101 |
| Shewanella loihica PV-4 | 0.36 | Shew_1722 | | dethiobiotin synthase (RefSeq) | 0.56 | Shew_0416 | | peptidase U62, modulator of DNA gyrase (RefSeq) | — | — |
| Rhodanobacter sp. FW510-T8 | 0.36 | OKGIIK_16455 | bioD | dethiobiotin synthase | 0.45 | OKGIIK_10260 | pmbA | metalloprotease PmbA | low | > 53 |
| Variovorax sp. OAS795 | 0.35 | ABID97_RS16255 | | dethiobiotin synthase | 0.45 | ABID97_RS20695 | | metalloprotease PmbA | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.35 | GFF3994 | | Dethiobiotin synthetase (EC 6.3.3.3) | 0.41 | GFF3655 | | TldE protein, part of TldE/TldD proteolytic complex | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.35 | Psyr_4683 | | dethiobiotin synthase | 0.47 | Psyr_4154 | | microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.35 | Psyr_4683 | | dethiobiotin synthase | 0.47 | Psyr_4154 | | microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 | low | > 86 |
| Shewanella amazonensis SB2B | 0.35 | Sama_1441 | bioD | dithiobiotin synthetase (RefSeq) | 0.58 | Sama_0482 | | PmbA protein (RefSeq) | — | — |
| Acidovorax sp. GW101-3H11 | 0.35 | Ac3H11_3829 | | Dethiobiotin synthetase (EC 6.3.3.3) | 0.42 | Ac3H11_3262 | | TldE protein, part of TldE/TldD proteolytic complex | low | > 79 |
| Pseudomonas stutzeri RCH2 | 0.34 | Psest_0415 | | dethiobiotin synthase | 0.46 | Psest_3318 | | Predicted Zn-dependent proteases and their inactivated homologs | low | > 67 |
| Pseudomonas sp. S08-1 | 0.34 | OH686_10335 | | dethiobiotin synthase | 0.47 | OH686_08570 | | TldE protein, part of TldE/TldD proteolytic complex | low | > 80 |
| Variovorax sp. SCN45 | 0.34 | GFF143 | | Dethiobiotin synthase BioD (EC 6.3.3.3) | 0.44 | GFF4697 | | TldE protein, part of TldE/TldD proteolytic complex | low | > 127 |
| Herbaspirillum seropedicae SmR1 | 0.33 | HSERO_RS12255 | | dethiobiotin synthetase | 0.42 | HSERO_RS09265 | | peptidase C69 | low | > 78 |
| Rhodanobacter denitrificans FW104-10B01 | 0.33 | LRK54_RS07180 | | dethiobiotin synthase | 0.44 | LRK54_RS03375 | | metalloprotease PmbA | low | > 59 |
| Burkholderia phytofirmans PsJN | 0.33 | BPHYT_RS02155 | | dithiobiotin synthetase | 0.41 | BPHYT_RS14705 | | peptidase C69 | low | > 109 |
| Lysobacter sp. OAE881 | 0.33 | ABIE51_RS17990 | | dethiobiotin synthase | 0.43 | ABIE51_RS06805 | | metalloprotease PmbA | low | > 62 |
| Alteromonas macleodii MIT1002 | 0.32 | MIT1002_01382 | | ATP-dependent dethiobiotin synthetase BioD 1 | 0.54 | MIT1002_00230 | | peptidase PmbA | low | > 70 |
| Rhodanobacter denitrificans MT42 | 0.32 | LRK55_RS06915 | | dethiobiotin synthase | 0.45 | LRK55_RS03125 | | metalloprotease PmbA | low | > 63 |
| Rhodanobacter sp000427505 FW510-R12 | 0.32 | LRK53_RS01195 | | dethiobiotin synthase | 0.45 | LRK53_RS06580 | | metalloprotease PmbA | — | — |
| Kangiella aquimarina DSM 16071 | 0.30 | B158DRAFT_0869 | | dethiobiotin synthase | 0.43 | B158DRAFT_2075 | | microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 | — | — |
| Pseudomonas aeruginosa PA14 | 0.30 | IKLFDK_22915 | | dethiobiotin synthase | 0.47 | IKLFDK_01720 | | metalloprotease PmbA | low | > 98 |
| Ralstonia sp. UNC404CL21Col | 0.30 | ABZR87_RS12345 | | dethiobiotin synthase | 0.42 | ABZR87_RS09660 | | metalloprotease PmbA | low | > 80 |
| Pseudomonas aeruginosa MRSN321 | 0.30 | DY961_RS22525 | bioD;go_function=dethiobiotin | dethiobiotin synthase | 0.47 | DY961_RS24115 | pmbA;go_function=metallopeptidase | metalloprotease PmbA | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.30 | H281DRAFT_02096 | | dethiobiotin synthetase | 0.42 | H281DRAFT_04304 | | microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 | low | > 103 |
| Pseudomonas aeruginosa PUPa3 | 0.30 | DQ20_RS36805 | bioD;go_function=dethiobiotin | dethiobiotin synthase | 0.47 | DQ20_RS56575 | pmbA;go_function=metallopeptidase | metalloprotease PmbA | — | — |
| Paraburkholderia graminis OAS925 | 0.29 | ABIE53_000578 | | dethiobiotin synthetase | 0.42 | ABIE53_003116 | | PmbA protein | low | > 113 |
| Ralstonia solanacearum UW163 | 0.29 | UW163_RS14160 | | dethiobiotin synthase | 0.42 | UW163_RS15845 | | metalloprotease PmbA | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.29 | RALBFv3_RS00825 | | dethiobiotin synthase | 0.42 | RALBFv3_RS13965 | | metalloprotease PmbA | — | — |
| Ralstonia solanacearum PSI07 | 0.28 | RPSI07_RS16695 | | dethiobiotin synthase | 0.42 | RPSI07_RS19505 | | metalloprotease PmbA | low | > 81 |
| Methylophilus sp. DMC18 | 0.28 | GFF1686 | | ATP-dependent dethiobiotin synthetase BioD 1 | 0.46 | GFF830 | | Metalloprotease PmbA | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.28 | RR42_RS00935 | | dethiobiotin synthetase | 0.40 | RR42_RS14750 | | peptidase PMbA | — | — |
| Ralstonia solanacearum GMI1000 | 0.27 | RS_RS07440 | | ATP-dependent dethiobiotin synthetase BioD | 0.41 | RS_RS04700 | | metalloprotease PmbA | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.27 | QEN71_RS01090 | | dethiobiotin synthase | 0.42 | QEN71_RS04270 | | metalloprotease PmbA | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.24 | Xcc-8004.4530.1 | | Dethiobiotin synthetase (EC 6.3.3.3) | 0.45 | Xcc-8004.1885.1 | | TldE protein, part of TldE/TldD proteolytic complex | low | > 74 |
| Sphingobium sp. HT1-2 | 0.17 | GFF3209 | | Dethiobiotin synthase BioD (EC 6.3.3.3) | 0.30 | GFF1059 | | TldE protein, part of TldE/TldD proteolytic complex | low | > 95 |
| Synechococcus elongatus PCC 7942 | 0.17 | Synpcc7942_0030 | bioD | dethiobiotin synthase | 0.09 | Synpcc7942_1289 | pmbA | putative modulator of DNA gyrase | — | — |
| Magnetospirillum magneticum AMB-1 | 0.16 | AMB_RS13890 | | ATP-dependent dethiobiotin synthetase BioD | 0.27 | AMB_RS22120 | | TldD/PmbA family protein | — | — |
| Agrobacterium fabrum C58 | 0.16 | Atu3999 | | dithiobiotin synthetase | 0.25 | Atu0693 | | PmbA/TldD related protein | low | > 89 |
| Castellaniella sp019104865 MT123 | 0.15 | ABCV34_RS15285 | | dethiobiotin synthase | 0.44 | ABCV34_RS10610 | | metalloprotease PmbA | low | > 48 |
| Sphingomonas koreensis DSMZ 15582 | 0.15 | Ga0059261_3673 | | dethiobiotin synthase | 0.31 | Ga0059261_0810 | | Predicted Zn-dependent proteases and their inactivated homologs | low | > 68 |
| Rhizobium sp. OAE497 | 0.14 | ABIE40_RS21065 | | dethiobiotin synthase | 0.25 | ABIE40_RS03780 | | TldD/PmbA family protein | 0.61 | 12 |
| Phaeobacter inhibens DSM 17395 | 0.14 | PGA1_c09140 | | dethiobiotin synthetase BioD | 0.28 | PGA1_c33480 | | protein PmbA | — | — |
| Rhodopseudomonas palustris CGA009 | 0.14 | TX73_015410 | | dethiobiotin synthase | 0.28 | TX73_005930 | | TldD/PmbA family protein | low | > 86 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.14 | CA265_RS09760 | | dethiobiotin synthase | 0.06 | CA265_RS02445 | | peptidase C69 | low | > 88 |
Not shown: 3 genomes with orthologs for CSW01_05660 only; 12 genomes with orthologs for CSW01_12845 only