| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_10060 | | YchF/TatD family DNA exonuclease | 1.0 | CSW01_11795 | | LysR family transcriptional regulator | 0.44 | 9 |
| Dickeya dadantii 3937 | 0.57 | DDA3937_RS13085 | | metal-dependent hydrolase | 0.33 | DDA3937_RS09260 | | LysR family transcriptional regulator | low | > 74 |
| Pantoea agglomerans CFBP13505 P0401 | 0.57 | PagCFBP13505_RS05300 | | metal-dependent hydrolase | 0.32 | PagCFBP13505_RS00780 | | LysR family transcriptional regulator | low | > 74 |
| Pantoea sp. MT58 | 0.57 | IAI47_12035 | | metal-dependent hydrolase | 0.32 | IAI47_06680 | | LysR family transcriptional regulator | low | > 76 |
| Dickeya dianthicola 67-19 | 0.57 | HGI48_RS13150 | | metal-dependent hydrolase | 0.33 | HGI48_RS09285 | | LysR family transcriptional regulator | low | > 71 |
| Rahnella sp. WP5 | 0.57 | EX31_RS24470 | | metal-dependent hydrolase | 0.32 | EX31_RS19050 | | LysR family transcriptional regulator | low | > 89 |
| Dickeya dianthicola ME23 | 0.57 | DZA65_RS13620 | | metal-dependent hydrolase | 0.32 | DZA65_RS09590 | | LysR family transcriptional regulator | low | > 75 |
| Shewanella amazonensis SB2B | 0.57 | Sama_2040 | | TatD family hydrolase (RefSeq) | 0.29 | Sama_1882 | | LysR family transcriptional regulator (RefSeq) | low | > 62 |
| Erwinia tracheiphila SCR3 | 0.57 | LU632_RS14785 | | metal-dependent hydrolase | 0.30 | LU632_RS17295 | | LysR family transcriptional regulator | low | > 73 |
| Serratia liquefaciens MT49 | 0.56 | IAI46_09825 | | metal-dependent hydrolase | 0.34 | IAI46_17215 | | LysR family transcriptional regulator | low | > 87 |
| Erwinia tracheiphila HP pepo 2.2 | 0.56 | IJEDHG_00645 | | metal-dependent hydrolase | 0.30 | IJEDHG_25865 | yieE | DNA-binding transcriptional regulator YeiE | low | > 61 |
| Erwinia amylovora T8 | 0.56 | OLJFJH_15495 | | metal-dependent hydrolase | 0.32 | OLJFJH_11795 | | DNA-binding transcriptional regulator YeiE | low | > 58 |
| Pectobacterium carotovorum WPP14 | 0.56 | HER17_RS08685 | | metal-dependent hydrolase | 0.33 | HER17_RS12840 | | LysR family transcriptional regulator | low | > 75 |
| Klebsiella michiganensis M5al | 0.55 | BWI76_RS11125 | | metal-dependent hydrolase | 0.31 | BWI76_RS19690 | | LysR family transcriptional regulator | low | > 92 |
| Enterobacter sp. TBS_079 | 0.54 | MPMX20_01780 | | putative metal-dependent hydrolase YcfH | 0.31 | MPMX20_03128 | | HTH-type transcriptional activator CmpR | low | > 85 |
| Klebsiella pneumoniae MKP103 | 0.54 | KDGMDA_18730 | | metal-dependent hydrolase | 0.31 | KDGMDA_26645 | | DNA-binding transcriptional regulator YeiE | 0.26 | 2 |
| Escherichia coli ECOR27 | 0.54 | NOLOHH_21070 | ycfH | metal-dependent hydrolase | 0.29 | NOLOHH_15070 | yieE | DNA-binding transcriptional regulator YeiE | — | — |
| Escherichia coli ECRC98 | 0.54 | JDDGAC_07200 | ycfH | metal-dependent hydrolase | 0.32 | JDDGAC_27455 | yieE | DNA-binding transcriptional regulator YeiE | low | > 87 |
| Escherichia coli BL21 | 0.54 | ECD_01096 | | putative DNase | 0.32 | ECD_02086 | | putative DNA-binding transcriptional regulator | low | > 61 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.54 | OHPLBJKB_02566 | | putative metal-dependent hydrolase YcfH | 0.32 | OHPLBJKB_01554 | | HTH-type transcriptional regulator CysL | low | > 74 |
| Escherichia coli ECRC102 | 0.54 | NIAGMN_24290 | ycfH | metal-dependent hydrolase | 0.32 | NIAGMN_21260 | yieE | DNA-binding transcriptional regulator YeiE | low | > 80 |
| Escherichia coli ECRC99 | 0.54 | KEDOAH_24215 | ycfH | metal-dependent hydrolase | 0.32 | KEDOAH_04690 | yieE | DNA-binding transcriptional regulator YeiE | — | — |
| Escherichia coli BW25113 | 0.54 | b1100 | ycfH | predicted metallodependent hydrolase (NCBI) | 0.32 | b2157 | yeiE | predicted DNA-binding transcriptional regulator (NCBI) | low | > 76 |
| Escherichia coli ECRC101 | 0.54 | MCAODC_22900 | ycfH | metal-dependent hydrolase | 0.32 | MCAODC_14545 | yieE | DNA-binding transcriptional regulator YeiE | low | > 87 |
| Shewanella oneidensis MR-1 | 0.54 | SO2610 | | hydrolase, TatD family (NCBI ptt file) | 0.24 | SO2561 | | transcriptional regulator, LysR family (NCBI ptt file) | low | > 76 |
| Escherichia coli ECRC62 | 0.54 | BNILDI_19230 | ycfH | metal-dependent hydrolase | 0.32 | BNILDI_13990 | yieE | DNA-binding transcriptional regulator YeiE | low | > 75 |
| Escherichia coli ECRC100 | 0.54 | OKFHMN_03540 | ycfH | metal-dependent hydrolase | 0.32 | OKFHMN_23495 | yieE | DNA-binding transcriptional regulator YeiE | low | > 79 |
| Escherichia coli ECOR38 | 0.54 | HEPCGN_23940 | ycfH | metal-dependent hydrolase | 0.32 | HEPCGN_22760 | yieE | DNA-binding transcriptional regulator YeiE | low | > 88 |
| Escherichia coli Nissle 1917 | 0.54 | ECOLIN_RS06350 | | metal-dependent hydrolase | 0.32 | ECOLIN_RS12630 | | DNA-binding transcriptional regulator YeiE | low | > 55 |
| Escherichia fergusonii Becca | 0.53 | EFB2_02875 | | putative metal-dependent hydrolase YcfH | 0.29 | EFB2_01699 | | HTH-type transcriptional regulator CysL | low | > 86 |
| Enterobacter asburiae PDN3 | 0.53 | EX28DRAFT_1829 | | hydrolase, TatD family | 0.31 | EX28DRAFT_0399 | | Transcriptional regulator | low | > 76 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.53 | GFF3382 | | Putative deoxyribonuclease YcfH | 0.32 | GFF3777 | | LysR family transcriptional regulator YeiE | low | > 78 |
| Shewanella sp. ANA-3 | 0.53 | Shewana3_1769 | | TatD family hydrolase (RefSeq) | 0.24 | Shewana3_2367 | | LysR family transcriptional regulator (RefSeq) | low | > 73 |
| Shewanella loihica PV-4 | 0.53 | Shew_1582 | | TatD family hydrolase (RefSeq) | 0.68 | Shew_2531 | | LysR family transcriptional regulator (RefSeq) | low | > 60 |
| Pseudomonas fluorescens FW300-N2E2 | 0.52 | Pf6N2E2_5960 | | Putative deoxyribonuclease YcfH | 0.36 | Pf6N2E2_2984 | | LysR family transcriptional regulator PA3398 | low | > 103 |
| Pseudomonas fluorescens FW300-N2E3 | 0.52 | AO353_01325 | | hydrolase TatD | 0.36 | AO353_16845 | | LysR family transcriptional regulator | low | > 101 |
| Pseudomonas fluorescens FW300-N2C3 | 0.52 | AO356_20205 | | hydrolase TatD | 0.35 | AO356_05630 | | LysR family transcriptional regulator | low | > 104 |
| Pseudomonas sp. RS175 | 0.51 | PFR28_03002 | | putative metal-dependent hydrolase YcfH | 0.36 | PFR28_00480 | | HTH-type transcriptional activator CmpR | low | > 88 |
| Pseudomonas segetis P6 | 0.51 | ACVTMO_RS10350 | | TatD family hydrolase | 0.36 | ACVTMO_RS16460 | | LysR family transcriptional regulator | low | > 75 |
| Pseudomonas fluorescens SBW25-INTG | 0.51 | PFLU_RS23020 | | TatD family hydrolase | 0.35 | PFLU_RS05920 | | LysR family transcriptional regulator | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.51 | PFLU_RS23020 | | TatD family hydrolase | 0.35 | PFLU_RS05920 | | LysR family transcriptional regulator | low | > 109 |
| Pseudomonas putida KT2440 | 0.51 | PP_1967 | | tRNA D-aminoacylase | 0.36 | PP_1637 | | Transcriptional regulator, LysR family | low | > 96 |
| Pseudomonas stutzeri RCH2 | 0.51 | Psest_1696 | | hydrolase, TatD family | 0.36 | Psest_2863 | | Transcriptional regulator | low | > 67 |
| Pseudomonas sp. BP01 | 0.51 | JOY50_RS16755 | | TatD family hydrolase | 0.36 | JOY50_RS23820 | finR | LysR family transcriptional regulator FinR | low | > 84 |
| Pseudomonas simiae WCS417 | 0.51 | PS417_21405 | | hydrolase TatD | 0.35 | PS417_05850 | | LysR family transcriptional regulator | low | > 88 |
| Pseudomonas aeruginosa MRSN321 | 0.50 | DY961_RS02180 | | TatD family hydrolase | 0.35 | DY961_RS15945 | | LysR family transcriptional regulator | low | > 100 |
| Pseudomonas lactucae CFBP13502 | 0.50 | GEMAOFIL_04425 | | putative metal-dependent hydrolase YcfH | 0.35 | GEMAOFIL_01341 | | HTH-type transcriptional activator CmpR | low | > 96 |
| Pseudomonas aeruginosa PA14 | 0.50 | IKLFDK_15055 | | hydrolase TatD | 0.35 | IKLFDK_17440 | | LysR family transcriptional regulator | low | > 98 |
| Pseudomonas aeruginosa PUPa3 | 0.50 | DQ20_RS33405 | | TatD family hydrolase | 0.35 | DQ20_RS41135 | | LysR family transcriptional regulator | low | > 101 |
| Pseudomonas sp. DMC3 | 0.50 | GFF4749 | | putative metal-dependent hydrolase YcfH | 0.36 | GFF2119 | | HTH-type transcriptional activator CmpR | 0.55 | 28 |
| Pseudomonas fluorescens GW456-L13 | 0.50 | PfGW456L13_2112 | | Putative deoxyribonuclease YcfH | 0.34 | PfGW456L13_4660 | | LysR family transcriptional regulator PA3398 | low | > 87 |
| Pseudomonas syringae pv. syringae B728a | 0.50 | Psyr_1655 | | TatD-related deoxyribonuclease | 0.36 | Psyr_1386 | | transcriptional regulator, LysR family | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.50 | Psyr_1655 | | TatD-related deoxyribonuclease | 0.36 | Psyr_1386 | | transcriptional regulator, LysR family | low | > 86 |
| Pseudomonas sp. S08-1 | 0.50 | OH686_22180 | | Uncharacterized metal-dependent hydrolase YcfH | 0.36 | OH686_18820 | | Transcriptional regulator, LysR family | low | > 80 |
| Pseudomonas orientalis W4I3 | 0.49 | QF045_RS23485 | | TatD family hydrolase | 0.35 | QF045_RS08765 | | LysR family transcriptional regulator | low | > 93 |
| Herbaspirillum seropedicae SmR1 | 0.49 | HSERO_RS12995 | | DNAase | 0.31 | HSERO_RS21575 | | transcriptional regulator | low | > 78 |
| Castellaniella sp019104865 MT123 | 0.49 | ABCV34_RS03960 | | TatD family hydrolase | 0.30 | ABCV34_RS05920 | | LysR substrate-binding domain-containing protein | low | > 48 |
| Pseudomonas fluorescens FW300-N1B4 | 0.49 | Pf1N1B4_420 | | Putative deoxyribonuclease YcfH | 0.36 | Pf1N1B4_3152 | | LysR family transcriptional regulator PA3398 | low | > 87 |
| Dechlorosoma suillum PS | 0.49 | Dsui_2652 | | hydrolase, TatD family | 0.33 | Dsui_2257 | | transcriptional regulator | low | > 51 |
| Pseudomonas sp. SVBP6 | 0.48 | COO64_RS05770 | | TatD family hydrolase | 0.37 | COO64_RS19970 | | LysR family transcriptional regulator | low | > 93 |
| Ralstonia sp. UNC404CL21Col | 0.48 | ABZR87_RS12460 | | TatD family hydrolase | 0.30 | ABZR87_RS10365 | | LysR family transcriptional regulator | low | > 80 |
| Ralstonia solanacearum UW163 | 0.47 | UW163_RS14320 | | TatD family deoxyribonuclease | 0.29 | UW163_RS12175 | | LysR family transcriptional regulator | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.47 | RR42_RS10885 | | DNAase | 0.30 | RR42_RS13965 | | LysR family transcriptional regulator | low | > 128 |
| Ralstonia solanacearum PSI07 | 0.47 | RPSI07_RS16465 | | TatD family deoxyribonuclease | 0.28 | RPSI07_RS18655 | | LysR family transcriptional regulator | low | > 81 |
| Ralstonia solanacearum IBSBF1503 | 0.47 | RALBFv3_RS01010 | | TatD family deoxyribonuclease | 0.29 | RALBFv3_RS14705 | | LysR family transcriptional regulator | low | > 76 |
| Ralstonia solanacearum GMI1000 | 0.47 | RS_RS09020 | | TatD family deoxyribonuclease | 0.28 | RS_RS05515 | | LysR family transcriptional regulator | low | > 80 |
| Methylophilus sp. DMC18 | 0.46 | GFF632 | | putative metal-dependent hydrolase YcfH | 0.33 | GFF1962 | | HTH-type transcriptional activator CmpR | low | > 43 |
| Burkholderia phytofirmans PsJN | 0.45 | BPHYT_RS09640 | | DNAase | 0.17 | BPHYT_RS07470 | | LysR family transcriptional regulator | — | — |
| Azospirillum brasilense Sp245 | 0.45 | AZOBR_RS08795 | | LuxR family transcriptional regulator | 0.22 | AZOBR_RS32560 | | LysR family transcriptional regulator | low | > 97 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.45 | H281DRAFT_00931 | | TatD DNase family protein | 0.18 | H281DRAFT_03013 | | transcriptional regulator, LysR family | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.44 | ABIE53_002166 | | TatD DNase family protein | 0.17 | ABIE53_005077 | | DNA-binding transcriptional LysR family regulator | low | > 113 |
| Azospirillum sp. SherDot2 | 0.44 | MPMX19_01469 | | putative metal-dependent hydrolase YcfH | 0.22 | MPMX19_00813 | | HTH-type transcriptional regulator CysL | low | > 112 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.44 | GFF4665 | | Putative deoxyribonuclease YcfH | 0.24 | GFF333 | | LysR family transcriptional regulator YeiE | low | > 90 |
| Paraburkholderia sabiae LMG 24235 | 0.44 | QEN71_RS21805 | | TatD family hydrolase | 0.18 | QEN71_RS34015 | | LysR family transcriptional regulator | low | > 153 |
| Acidovorax sp. GW101-3H11 | 0.42 | Ac3H11_2488 | | Putative deoxyribonuclease YcfH | 0.15 | Ac3H11_3174 | | RuBisCO operon transcriptional regulator | low | > 79 |
| Variovorax sp. OAS795 | 0.42 | ABID97_RS16000 | | TatD family hydrolase | 0.17 | ABID97_RS12840 | | LysR family transcriptional regulator | — | — |
| Variovorax sp. SCN45 | 0.42 | GFF34 | | Uncharacterized metal-dependent hydrolase YcfH | 0.27 | GFF3160 | | Transcriptional regulator YeiE, LysR family | low | > 127 |
| Rhodopseudomonas palustris CGA009 | 0.40 | TX73_014390 | | TatD family hydrolase | 0.20 | TX73_009100 | | LysR family transcriptional regulator | low | > 86 |
| Rhodospirillum rubrum S1H | 0.40 | Rru_A1700 | | TatD-related deoxyribonuclease (NCBI) | 0.22 | Rru_A0606 | | Transcriptional Regulator, LysR family (NCBI) | — | — |
| Acinetobacter radioresistens SK82 | 0.39 | MPMX26_01224 | | putative metal-dependent hydrolase YcfH | 0.33 | MPMX26_02541 | | HTH-type transcriptional regulator CysL | low | > 36 |
| Acinetobacter baumannii LAC-4 | 0.39 | RR41_RS12075 | | TatD family hydrolase | 0.32 | RR41_RS15435 | | LysR family transcriptional regulator GigC | low | > 55 |
| Xanthobacter sp. DMC5 | 0.38 | GFF695 | | D-aminoacyl-tRNA deacylase | 0.19 | GFF3980 | | HTH-type transcriptional regulator HdfR | — | — |
| Bosea sp. OAE506 | 0.38 | ABIE41_RS15945 | | TatD family hydrolase | 0.14 | ABIE41_RS16445 | | LysR substrate-binding domain-containing protein | low | > 77 |
| Sinorhizobium meliloti 1021 | 0.37 | SMc01193 | | hypothetical protein | 0.19 | SM_b20203 | | transcriptional regulator | — | — |
| Agrobacterium fabrum C58 | 0.37 | Atu1495 | | hypothetical protein | 0.19 | Atu0672 | | transcriptional regulator, LysR family | low | > 89 |
| Rhizobium sp. OAE497 | 0.36 | ABIE40_RS09480 | | TatD family hydrolase | 0.22 | ABIE40_RS15535 | | LysR family transcriptional regulator | low | > 107 |
| Marinobacter adhaerens HP15 | 0.34 | HP15_3420 | | hydrolase, TatD family | 0.27 | HP15_2201 | | transcriptional regulator, LysR family | low | > 73 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.34 | A4249_RS04755 | | TatD family hydrolase | 0.21 | A4249_RS01115 | | LysR substrate-binding domain-containing protein | low | > 48 |
| Synechocystis sp000284455 PCC 6803 | 0.34 | SGL_RS05935 | | TatD family hydrolase | 0.17 | SGL_RS08845 | | LysR family transcriptional regulator | — | — |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.31 | DVU3202 | | hydrolase, TatD family (TIGR) | 0.15 | DVU1331 | | transcriptional regulator, LysR family (TIGR) | low | > 55 |
| Dyella japonica UNC79MFTsu3.2 | 0.25 | ABZR86_RS13140 | | TatD family hydrolase | 0.33 | ABZR86_RS19780 | | LysR family transcriptional regulator | low | > 74 |
| Methanococcus maripaludis JJ | 0.23 | MMJJ_RS06285 | | YchF/TatD family DNA exonuclease | 0.16 | MMJJ_RS05540 | | LysR family transcriptional regulator | low | > 28 |
| Methanococcus maripaludis S2 | 0.22 | MMP_RS08080 | | YchF/TatD family DNA exonuclease | 0.17 | MMP_RS08815 | | LysR family transcriptional regulator | — | — |
Not shown: 12 genomes with orthologs for CSW01_10060 only; 9 genomes with orthologs for CSW01_11795 only