| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_02425 | | YggW family oxidoreductase | 1.0 | CSW01_10730 | | ArsC family reductase | 0.56 | 8 |
| Pectobacterium carotovorum WPP14 | 0.69 | HER17_RS03785 | | radical SAM family heme chaperone HemW | 0.40 | HER17_RS15305 | | ArsC family reductase | low | > 75 |
| Dickeya dadantii 3937 | 0.68 | DDA3937_RS17325 | | radical SAM family heme chaperone HemW | 0.41 | DDA3937_RS06110 | | ArsC family reductase | low | > 74 |
| Dickeya dianthicola 67-19 | 0.68 | HGI48_RS17370 | | radical SAM family heme chaperone HemW | 0.41 | HGI48_RS06155 | | ArsC family reductase | low | > 71 |
| Dickeya dianthicola ME23 | 0.68 | DZA65_RS18460 | | radical SAM family heme chaperone HemW | 0.42 | DZA65_RS06505 | | ArsC family reductase | low | > 75 |
| Serratia liquefaciens MT49 | 0.68 | IAI46_21435 | | radical SAM family heme chaperone HemW | 0.45 | IAI46_18735 | | ArsC family reductase | low | > 87 |
| Escherichia coli ECRC98 | 0.67 | JDDGAC_22865 | hemW | radical SAM family heme chaperone HemW | 0.45 | JDDGAC_25905 | yffB | ArsC family reductase | low | > 87 |
| Escherichia coli ECRC101 | 0.67 | MCAODC_09755 | hemW | radical SAM family heme chaperone HemW | 0.45 | MCAODC_12490 | yffB | ArsC family reductase | low | > 87 |
| Escherichia coli ECRC99 | 0.67 | KEDOAH_08905 | hemW | radical SAM family heme chaperone HemW | 0.44 | KEDOAH_06260 | arsC | ArsC family reductase | — | — |
| Escherichia coli ECRC102 | 0.67 | NIAGMN_17000 | hemW | radical SAM family heme chaperone HemW | 0.45 | NIAGMN_19730 | yffB | ArsC family reductase | 0.72 | 7 |
| Escherichia coli ECRC100 | 0.67 | OKFHMN_19235 | hemW | radical SAM family heme chaperone HemW | 0.45 | OKFHMN_21960 | yffB | ArsC family reductase | low | > 79 |
| Escherichia fergusonii Becca | 0.66 | EFB2_00947 | | Heme chaperone HemW | 0.44 | EFB2_01417 | | Protein YffB | low | > 86 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.66 | OHPLBJKB_00761 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YqeR | 0.45 | OHPLBJKB_01260 | | Protein YffB | low | > 74 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.66 | GFF3058 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.45 | GFF2187 | | FIG138056: a glutathione-dependent thiol reductase | — | — |
| Escherichia coli BW25113 | 0.66 | b2955 | yggW | coproporphyrinogen III oxidase (NCBI) | 0.44 | b2471 | yffB | hypothetical protein (NCBI) | low | > 76 |
| Escherichia coli BL21 | 0.66 | ECD_02785 | | HemN family putative oxidoreductase | 0.44 | ECD_02362 | | putative ArsC family reductase | — | — |
| Escherichia coli ECRC62 | 0.66 | BNILDI_09685 | hemW | radical SAM family heme chaperone HemW | 0.45 | BNILDI_12450 | arsC | ArsC family reductase | low | > 75 |
| Erwinia tracheiphila SCR3 | 0.66 | LU632_RS05445 | hemW | radical SAM family heme chaperone HemW | 0.37 | LU632_RS08360 | | ArsC family reductase | low | > 73 |
| Escherichia coli Nissle 1917 | 0.65 | ECOLIN_RS16435 | | radical SAM family heme chaperone HemW | 0.43 | ECOLIN_RS14100 | | ArsC family reductase | — | — |
| Escherichia coli ECOR38 | 0.65 | HEPCGN_18540 | hemW | radical SAM family heme chaperone HemW | 0.44 | HEPCGN_21130 | arsC | ArsC family reductase | low | > 88 |
| Escherichia coli ECOR27 | 0.65 | NOLOHH_11105 | hemW | radical SAM family heme chaperone HemW | 0.45 | NOLOHH_13640 | arsC | ArsC family reductase | low | > 76 |
| Enterobacter sp. TBS_079 | 0.65 | MPMX20_03813 | | Heme chaperone HemW | 0.42 | MPMX20_03332 | | Protein YffB | low | > 85 |
| Pantoea agglomerans CFBP13505 P0401 | 0.65 | PagCFBP13505_RS16115 | | radical SAM family heme chaperone HemW | 0.40 | PagCFBP13505_RS19850 | | ArsC family reductase | low | > 74 |
| Enterobacter asburiae PDN3 | 0.65 | EX28DRAFT_2993 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.43 | EX28DRAFT_0190 | | transcriptional regulator, Spx/MgsR family | low | > 76 |
| Pantoea sp. MT58 | 0.65 | IAI47_03580 | | radical SAM family heme chaperone HemW | 0.40 | IAI47_05305 | | ArsC family reductase | low | > 76 |
| Klebsiella michiganensis M5al | 0.65 | BWI76_RS24120 | | YggW family oxidoreductase | 0.42 | BWI76_RS20865 | | arsenate reductase | low | > 92 |
| Klebsiella pneumoniae MKP103 | 0.64 | KDGMDA_04635 | | radical SAM family heme chaperone HemW | 0.41 | KDGMDA_27705 | | ArsC family reductase | low | > 95 |
| Erwinia amylovora T8 | 0.64 | OLJFJH_08515 | | radical SAM family heme chaperone HemW | 0.44 | OLJFJH_10730 | | ArsC family reductase | low | > 58 |
| Rahnella sp. WP5 | 0.63 | EX31_RS02710 | | radical SAM family heme chaperone HemW | 0.38 | EX31_RS22800 | | ArsC family reductase | low | > 89 |
| Shewanella loihica PV-4 | 0.59 | Shew_1131 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | 0.45 | Shew_1863 | | arsenate reductase and related (RefSeq) | — | — |
| Shewanella sp. ANA-3 | 0.59 | Shewana3_1188 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | 0.44 | Shewana3_1913 | | arsenate reductase and related (RefSeq) | — | — |
| Shewanella oneidensis MR-1 | 0.59 | SO3359 | | oxygen-independent coproporphyrinogen III oxidase, putative (NCBI ptt file) | 0.44 | SO2470 | | conserved hypothetical protein (NCBI ptt file) | low | > 76 |
| Alteromonas macleodii MIT1002 | 0.59 | MIT1002_00939 | | Oxygen-independent coproporphyrinogen-III oxidase 1 | 0.52 | MIT1002_01546 | | Regulatory protein spx | low | > 70 |
| Shewanella amazonensis SB2B | 0.56 | Sama_2483 | | oxygen-independent coproporphyrinogen III oxidase, putative (RefSeq) | 0.44 | Sama_1648 | | hypothetical protein (RefSeq) | — | — |
| Pseudomonas sp. RS175 | 0.54 | PFR28_04249 | | Heme chaperone HemW | 0.43 | PFR28_00391 | | hypothetical protein | low | > 88 |
| Pseudomonas fluorescens FW300-N2E2 | 0.54 | Pf6N2E2_4593 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.42 | Pf6N2E2_3077 | | FIG138056: a glutathione-dependent thiol reductase | low | > 103 |
| Kangiella aquimarina DSM 16071 | 0.54 | B158DRAFT_0201 | | coproporphyrinogen III oxidase, anaerobic (EC 1.3.99.22) | 0.38 | B158DRAFT_1070 | | transcriptional regulator, Spx/MgsR family | low | > 40 |
| Pseudomonas fluorescens FW300-N2E3 | 0.53 | AO353_08200 | | coproporphyrinogen III oxidase | 0.42 | AO353_16440 | | ArsC family transcriptional regulator | low | > 101 |
| Pseudomonas fluorescens GW456-L13 | 0.53 | PfGW456L13_1003 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.44 | PfGW456L13_4715 | | FIG138056: a glutathione-dependent thiol reductase | low | > 87 |
| Pseudomonas fluorescens SBW25 | 0.53 | PFLU_RS28405 | | radical SAM family heme chaperone HemW | 0.44 | PFLU_RS06250 | | ArsC family reductase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.53 | PFLU_RS28405 | | radical SAM family heme chaperone HemW | 0.44 | PFLU_RS06250 | | ArsC family reductase | low | > 109 |
| Pseudomonas simiae WCS417 | 0.53 | PS417_26760 | | oxidase | 0.44 | PS417_06185 | | ArsC family transcriptional regulator | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.53 | Pf1N1B4_2334 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.43 | Pf1N1B4_3078 | | FIG138056: a glutathione-dependent thiol reductase | low | > 87 |
| Pseudomonas fluorescens FW300-N2C3 | 0.53 | AO356_13390 | | coproporphyrinogen III oxidase | 0.42 | AO356_06065 | | ArsC family transcriptional regulator | low | > 104 |
| Pseudomonas sp. DMC3 | 0.53 | GFF216 | | Heme chaperone HemW | 0.44 | GFF2048 | | Protein YffB | — | — |
| Pseudomonas aeruginosa PUPa3 | 0.52 | DQ20_RS37390 | hemW;go_function=coproporphyrinogen | radical SAM family heme chaperone HemW | 0.42 | DQ20_RS42470 | | ArsC family reductase | low | > 101 |
| Pseudomonas sp. SVBP6 | 0.52 | COO64_RS12965 | hemW | radical SAM family heme chaperone HemW | 0.41 | COO64_RS19615 | | ArsC family reductase | low | > 93 |
| Pseudomonas aeruginosa MRSN321 | 0.52 | DY961_RS21905 | hemW;go_function=coproporphyrinogen | radical SAM family heme chaperone HemW | 0.42 | DY961_RS14655 | | ArsC family reductase | low | > 100 |
| Pseudomonas aeruginosa PA14 | 0.51 | IKLFDK_23495 | | radical SAM family heme chaperone HemW | 0.43 | IKLFDK_18710 | | ArsC family reductase | low | > 98 |
| Pseudomonas segetis P6 | 0.51 | MPMX49_00603 | | Heme chaperone HemW | 0.43 | MPMX49_03466 | | Protein YffB | low | > 75 |
| Pseudomonas sp. BP01 | 0.51 | JOY50_RS20875 | hemW | radical SAM family heme chaperone HemW | 0.43 | JOY50_RS26165 | | ArsC family reductase | low | > 84 |
| Pseudomonas sp. S08-1 | 0.51 | OH686_11020 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW | 0.45 | OH686_06505 | | a glutathione-dependent thiol reductase | low | > 80 |
| Pseudomonas putida KT2440 | 0.51 | PP_5101 | | coproporphyrinogen/heterocyclic compound oxidase (aerobic) | 0.44 | PP_1531 | | putative glutathione-dependent thiol reductase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.50 | Psyr_0471 | | coproporphyrinogen III oxidase, anaerobic | 0.44 | Psyr_1337 | | Conserved hypothetical protein ArsC related protein | low | > 86 |
| Pseudomonas stutzeri RCH2 | 0.50 | Psest_0276 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.41 | Psest_1466 | | transcriptional regulator, Spx/MgsR family | low | > 67 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.50 | Psyr_0471 | | coproporphyrinogen III oxidase, anaerobic | 0.44 | Psyr_1337 | | Conserved hypothetical protein ArsC related protein | low | > 86 |
| Pseudomonas orientalis W4I3 | 0.50 | QF045_RS01160 | | radical SAM family heme chaperone HemW | 0.44 | QF045_RS09030 | | ArsC family reductase | low | > 93 |
| Pseudomonas lactucae CFBP13502 | 0.49 | GEMAOFIL_05489 | | Heme chaperone HemW | 0.44 | GEMAOFIL_01407 | | Protein YffB | low | > 96 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.48 | Xcc-8004.1224.1 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.33 | Xcc-8004.3540.1 | | FIG138056: a glutathione-dependent thiol reductase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.47 | ABZR86_RS11910 | | radical SAM family heme chaperone HemW | 0.36 | ABZR86_RS21560 | | Spx/MgsR family RNA polymerase-binding regulatory protein | low | > 74 |
| Lysobacter sp. OAE881 | 0.47 | ABIE51_RS17300 | | radical SAM family heme chaperone HemW | 0.34 | ABIE51_RS06990 | | Spx/MgsR family RNA polymerase-binding regulatory protein | low | > 62 |
| Rhodanobacter sp000427505 FW510-R12 | 0.46 | LRK53_RS16820 | | radical SAM family heme chaperone HemW | 0.33 | LRK53_RS14350 | | Spx/MgsR family RNA polymerase-binding regulatory protein | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.46 | LRK55_RS11460 | | radical SAM family heme chaperone HemW | 0.34 | LRK55_RS13980 | | Spx/MgsR family RNA polymerase-binding regulatory protein | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.46 | LRK54_RS11735 | | radical SAM family heme chaperone HemW | 0.34 | LRK54_RS14260 | | Spx/MgsR family RNA polymerase-binding regulatory protein | low | > 59 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.45 | H281DRAFT_04010 | | oxygen-independent coproporphyrinogen-3 oxidase | 0.41 | H281DRAFT_00598 | | arsenate reductase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.45 | RR42_RS04880 | | coproporphyrinogen III oxidase | 0.43 | RR42_RS11945 | | ArsC family transcriptional regulator | — | — |
| Rhodanobacter sp. FW510-T8 | 0.44 | OKGIIK_12160 | hemW | radical SAM family heme chaperone HemW | 0.34 | OKGIIK_03130 | | Arsenate reductase | low | > 53 |
| Burkholderia phytofirmans PsJN | 0.44 | BPHYT_RS15335 | | coproporphyrinogen III oxidase | 0.41 | BPHYT_RS12195 | | arsenate reductase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.44 | HSERO_RS10665 | | coproporphyrinogen III oxidase | 0.43 | HSERO_RS10795 | | arsenate reductase | — | — |
| Dechlorosoma suillum PS | 0.44 | Dsui_0491 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.40 | Dsui_2545 | | transcriptional regulator, Spx/MgsR family | low | > 51 |
| Paraburkholderia graminis OAS925 | 0.44 | ABIE53_003236 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.41 | ABIE53_002518 | | arsenate reductase | — | — |
| Variovorax sp. OAS795 | 0.44 | ABID97_RS23630 | | radical SAM family heme chaperone HemW | 0.37 | ABID97_RS21655 | | ArsC family reductase | low | > 91 |
| Paraburkholderia sabiae LMG 24235 | 0.44 | QEN71_RS03635 | | radical SAM family heme chaperone HemW | 0.42 | QEN71_RS06360 | | ArsC family reductase | low | > 153 |
| Ralstonia solanacearum PSI07 | 0.44 | RPSI07_RS13830 | | oxygen-independent coproporphyrinogen III oxidase-like protein | 0.43 | RPSI07_RS17170 | | arsenate reductase | low | > 81 |
| Variovorax sp. SCN45 | 0.44 | GFF2383 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW | 0.35 | GFF3093 | | FIG138056: a glutathione-dependent thiol reductase | low | > 127 |
| Marinobacter adhaerens HP15 | 0.43 | HP15_280 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.44 | HP15_1161 | | arsenate reductase | low | > 73 |
| Methylophilus sp. DMC18 | 0.43 | GFF2148 | | Heme chaperone HemW | 0.39 | GFF896 | | Protein YffB | low | > 43 |
| Ralstonia sp. UNC404CL21Col | 0.43 | ABZR87_RS15265 | | radical SAM family heme chaperone HemW | 0.44 | ABZR87_RS11755 | | arsenate reductase | low | > 80 |
| Ralstonia solanacearum GMI1000 | 0.42 | RS_RS10840 | | oxygen-independent coproporphyrinogen III oxidase-like protein | 0.38 | RS_RS06975 | | ArsC family reductase | — | — |
| Ralstonia solanacearum UW163 | 0.42 | UW163_RS10365 | | oxygen-independent coproporphyrinogen III oxidase-like protein | 0.42 | UW163_RS13635 | | ArsC family reductase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.42 | RALBFv3_RS03355 | | oxygen-independent coproporphyrinogen III oxidase-like protein | 0.42 | RALBFv3_RS00305 | | ArsC family reductase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.42 | GFF3256 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.34 | GFF296 | | FIG138056: a glutathione-dependent thiol reductase | — | — |
| Acinetobacter baumannii LAC-4 | 0.41 | RR41_RS17015 | | radical SAM family heme chaperone HemW | 0.36 | RR41_RS00790 | | arsenate reductase | low | > 55 |
| Acidovorax sp. GW101-3H11 | 0.41 | Ac3H11_3672 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.38 | Ac3H11_2613 | | FIG138056: a glutathione-dependent thiol reductase | low | > 79 |
| Rhodopseudomonas palustris CGA009 | 0.31 | TX73_001700 | | radical SAM family heme chaperone HemW | 0.43 | TX73_011755 | | ArsC family reductase | — | — |
| Rhizobium sp. OAE497 | 0.30 | ABIE40_RS01625 | | radical SAM family heme chaperone HemW | 0.44 | ABIE40_RS01235 | | ArsC family reductase | — | — |
| Bosea sp. OAE506 | 0.30 | ABIE41_RS03305 | | radical SAM family heme chaperone HemW | 0.45 | ABIE41_RS18295 | | ArsC family reductase | low | > 77 |
| Agrobacterium fabrum C58 | 0.30 | Atu0325 | | oxygen-independent coproporphyrinogen III oxidase | 0.47 | Atu0276 | | hypothetical protein | — | — |
| Sinorhizobium meliloti 1021 | 0.29 | SMc01147 | | coproporphyrinogen III oxidase | 0.50 | SMc00386 | | hypothetical protein | low | > 103 |
| Sphingobium sp. HT1-2 | 0.28 | GFF2622 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW | 0.41 | GFF670 | | FIG138056: a glutathione-dependent thiol reductase | low | > 95 |
| Phaeobacter inhibens DSM 17395 | 0.28 | PGA1_c35050 | | oxygen-independent coproporphyrinogen III oxidase HemN | 0.26 | PGA1_c21050 | | glutaredoxin-like protein | low | > 62 |
| Dinoroseobacter shibae DFL-12 | 0.28 | Dshi_3460 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | 0.21 | Dshi_0770 | | arsenate reductase and related (RefSeq) | — | — |
| Xanthobacter sp. DMC5 | 0.27 | GFF1891 | | hypothetical protein | 0.47 | GFF1300 | | Protein YffB | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.26 | A4249_RS12445 | | radical SAM family heme chaperone HemW | 0.45 | A4249_RS03665 | | ArsC family reductase | low | > 48 |
| Caulobacter crescentus NA1000 | 0.26 | CCNA_00144 | | oxygen-independent coproporphyrinogen-III oxidase | 0.43 | CCNA_01714 | | Spx/MgsR-related protein | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.26 | CCNA_00144 | | oxygen-independent coproporphyrinogen-III oxidase | 0.43 | CCNA_01714 | | Spx/MgsR-related protein | low | > 67 |
| Sphingomonas koreensis DSMZ 15582 | 0.25 | Ga0059261_2753 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.44 | Ga0059261_0315 | | transcriptional regulator, Spx/MgsR family | low | > 68 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.21 | ABZR88_RS03545 | | radical SAM family heme chaperone HemW | 0.36 | ABZR88_RS16335 | | Spx/MgsR family RNA polymerase-binding regulatory protein | — | — |
Not shown: 15 genomes with orthologs for CSW01_02425 only; 1 genomes with orthologs for CSW01_10730 only