Conservation of cofitness between BWI76_RS27450 and BWI76_RS04995 in Klebsiella michiganensis M5al

81 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS27450 ferredoxin--NADP(+) reductase 1.0 BWI76_RS04995 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.32 14
Enterobacter asburiae PDN3 0.90 EX28DRAFT_4397 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.95 EX28DRAFT_3730 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 76
Escherichia coli ECOR38 0.90 HEPCGN_12430 fpr ferredoxin--NADP(+) reductase 0.91 HEPCGN_08375 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 87
Escherichia coli ECRC101 0.90 MCAODC_04285 fpr ferredoxin--NADP(+) reductase 0.92 MCAODC_00915 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 87
Escherichia coli ECRC100 0.90 OKFHMN_13785 fpr ferredoxin--NADP(+) reductase 0.92 OKFHMN_10400 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 80
Escherichia coli ECRC99 0.90 KEDOAH_14375 fpr ferredoxin--NADP(+) reductase 0.91 KEDOAH_17755 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli ECRC102 0.90 NIAGMN_11540 fpr ferredoxin--NADP(+) reductase 0.92 NIAGMN_08250 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli ECRC62 0.90 BNILDI_05610 fpr ferredoxin--NADP(+) reductase 0.92 BNILDI_08925 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 75
Escherichia coli BL21 0.90 ECD_03809 ferredoxin-NADP reductase; flavodoxin reductase 0.92 ECD_00133 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 61
Escherichia coli ECRC98 0.90 JDDGAC_17410 fpr ferredoxin--NADP(+) reductase 0.92 JDDGAC_13995 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 86
Escherichia coli ECOR27 0.90 NOLOHH_05920 fpr ferredoxin--NADP(+) reductase 0.92 NOLOHH_02745 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 75
Enterobacter sp. TBS_079 0.90 MPMX20_04545 Flavodoxin/ferredoxin--NADP reductase 0.94 MPMX20_00827 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.89 OHPLBJKB_04127 Flavodoxin/ferredoxin--NADP reductase 0.92 OHPLBJKB_03527 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 73
Escherichia coli BW25113 0.89 b3924 fpr ferredoxin-NADP reductase (NCBI) 0.91 b0134 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI) low > 76
Escherichia coli Nissle 1917 0.89 ECOLIN_RS22600 ferredoxin--NADP(+) reductase 0.91 ECOLIN_RS00745 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia fergusonii Becca 0.89 EFB2_04694 Flavodoxin/ferredoxin--NADP reductase 0.91 EFB2_03910 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.87 GFF2305 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.96 GFF91 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 78
Dickeya dianthicola ME23 0.79 DZA65_RS21540 ferredoxin--NADP(+) reductase 0.76 DZA65_RS17155 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 75
Rahnella sp. WP5 0.79 EX31_RS14285 ferredoxin--NADP(+) reductase 0.80 EX31_RS03280 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 89
Dickeya dianthicola 67-19 0.79 HGI48_RS20495 ferredoxin--NADP(+) reductase 0.76 HGI48_RS16070 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.72 11
Pectobacterium carotovorum WPP14 0.79 HER17_RS00815 ferredoxin--NADP(+) reductase 0.79 HER17_RS05560 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 75
Dickeya dadantii 3937 0.78 DDA3937_RS00880 ferredoxin--NADP(+) reductase 0.76 DDA3937_RS15955 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Serratia liquefaciens MT49 0.78 IAI46_24620 ferredoxin--NADP(+) reductase 0.78 IAI46_21240 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 86
Pantoea sp. MT58 0.77 IAI47_00810 ferredoxin--NADP(+) reductase 0.76 IAI47_15655 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 76
Erwinia tracheiphila SCR3 0.73 LU632_RS19715 fpr ferredoxin--NADP(+) reductase 0.79 LU632_RS20100 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.66 43
Shewanella amazonensis SB2B 0.47 Sama_0663 ferredoxin--NADP reductase (RefSeq) 0.66 Sama_0776 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Shewanella loihica PV-4 0.45 Shew_0858 oxidoreductase FAD/NAD(P)-binding subunit (RefSeq) 0.67 Shew_3133 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Shewanella sp. ANA-3 0.41 Shewana3_3520 oxidoreductase FAD/NAD(P)-binding subunit (RefSeq) 0.65 Shewana3_3408 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.40 SO0747 fpr ferredoxin--NADP reductase (NCBI ptt file) 0.66 SO0870 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI ptt file) low > 76
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS26250 ferredoxin--NADP reductase 0.56 PFLU_RS25750 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 109
Pseudomonas fluorescens SBW25 0.40 PFLU_RS26250 ferredoxin--NADP reductase 0.56 PFLU_RS25750 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 109
Pseudomonas fluorescens FW300-N2C3 0.39 AO356_15660 ferredoxin-NADP reductase 0.59 AO356_16060 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 104
Pseudomonas simiae WCS417 0.39 PS417_24325 ferredoxin-NADP reductase 0.57 PS417_23910 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pseudomonas stutzeri RCH2 0.39 Psest_3439 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.56 Psest_0996 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pseudomonas fluorescens FW300-N2E2 0.38 Pf6N2E2_5072 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.58 Pf6N2E2_5153 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 103
Pseudomonas sp. S08-1 0.38 OH686_16145 Ferredoxin--NADP(+) reductase or Flavodoxin--NADP(+) reductase 0.58 OH686_17245 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pseudomonas sp. RS175 0.38 PFR28_03796 Flavodoxin/ferredoxin--NADP reductase 0.58 PFR28_03721 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 88
Pseudomonas fluorescens FW300-N2E3 0.37 AO353_13960 ferredoxin-NADP reductase 0.58 AO353_14385 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 101
Pseudomonas fluorescens FW300-N1B4 0.37 Pf1N1B4_2764 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.58 Pf1N1B4_2854 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 87
Pseudomonas putida KT2440 0.37 PP_4646 ferredoxin--NADP(+) reductase 0.57 PP_4699 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_1440 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.58 PfGW456L13_1521 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 87
Herbaspirillum seropedicae SmR1 0.37 HSERO_RS07730 ferredoxin-NADP reductase 0.54 HSERO_RS03085 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 78
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_4277 Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region 0.55 Psyr_0828 ketopantoate hydroxymethyltransferase low > 86
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_4277 Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region 0.55 Psyr_0828 ketopantoate hydroxymethyltransferase — —
Acinetobacter radioresistens SK82 0.35 MPMX26_02540 Flavodoxin/ferredoxin--NADP reductase 0.49 MPMX26_00545 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Dechlorosoma suillum PS 0.30 Dsui_2127 flavodoxin reductase family protein 0.44 Dsui_1471 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Paraburkholderia graminis OAS925 0.30 ABIE53_000451 ferredoxin--NADP+ reductase 0.51 ABIE53_000867 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Paraburkholderia bryophila 376MFSha3.1 0.30 H281DRAFT_02177 ferredoxin--NADP+ reductase 0.52 H281DRAFT_04703 ketopantoate hydroxymethyltransferase — —
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS26685 ferredoxin-NADP reductase 0.43 RR42_RS17250 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Burkholderia phytofirmans PsJN 0.30 BPHYT_RS01800 ferredoxin--NADP reductase 0.49 BPHYT_RS03605 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Paraburkholderia sabiae LMG 24235 0.29 QEN71_RS00515 ferredoxin--NADP reductase 0.51 QEN71_RS26480 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Castellaniella sp019104865 MT123 0.29 ABCV34_RS03560 ferredoxin--NADP reductase 0.34 ABCV34_RS13815 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS18185 ferredoxin--NADP reductase 0.46 ABZR86_RS00815 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Azospirillum sp. SherDot2 0.29 MPMX19_05828 Ferredoxin--NADP reductase 0.35 MPMX19_01580 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Alteromonas macleodii MIT1002 0.28 MIT1002_02652 Ferredoxin--NADP reductase 0.65 MIT1002_03694 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodanobacter sp. FW510-T8 0.28 OKGIIK_00495 fpr ferredoxin--NADP(+) reductase 0.48 OKGIIK_03885 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.56 16
Azospirillum brasilense Sp245 0.28 AZOBR_RS02415 ferredoxin--NADP reductase 0.36 AZOBR_RS06445 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodanobacter denitrificans MT42 0.28 LRK55_RS05870 ferredoxin--NADP reductase 0.48 LRK55_RS14830 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 63
Rhodanobacter denitrificans FW104-10B01 0.28 LRK54_RS06125 ferredoxin--NADP reductase 0.48 LRK54_RS15115 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Marinobacter adhaerens HP15 0.27 HP15_2200 oxidoreductase FAD/NAD(P)-binding domain protein 0.54 HP15_324 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodospirillum rubrum S1H 0.27 Rru_A0530 Ferredoxin--NADP+ reductase (NCBI) 0.30 Rru_A3321 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI) — —
Acidovorax sp. GW101-3H11 0.26 Ac3H11_3439 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.41 Ac3H11_3839 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) — —
Lysobacter sp. OAE881 0.26 ABIE51_RS09180 ferredoxin--NADP reductase 0.47 ABIE51_RS08025 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Xanthomonas campestris pv. campestris strain 8004 0.26 Xcc-8004.3508.1 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.50 Xcc-8004.3052.1 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) — —
Rhizobium sp. OAE497 0.26 ABIE40_RS09225 ferredoxin--NADP reductase 0.29 ABIE40_RS09465 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Agrobacterium fabrum C58 0.26 Atu1458 ferredoxin NADP+ reductase 0.32 Atu3483 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Ralstonia sp. UNC404CL21Col 0.25 ABZR87_RS11335 ferredoxin--NADP reductase 0.51 ABZR87_RS00950 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.25 GFF4298 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) 0.42 GFF1218 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) — —
Ralstonia solanacearum GMI1000 0.25 RS_RS06545 ferredoxin--NADP reductase 0.53 RS_RS13180 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Variovorax sp. SCN45 0.25 GFF6387 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) @ Flavodoxin--NADP(+) reductase (EC 1.19.1.1) 0.41 GFF2579 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) — —
Ralstonia solanacearum IBSBF1503 0.25 RALBFv3_RS15765 ferredoxin--NADP reductase 0.52 RALBFv3_RS05315 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Sinorhizobium meliloti 1021 0.25 SMc02122 ferredoxin--NADP reductase 0.33 SMc01881 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Ralstonia solanacearum UW163 0.25 UW163_RS13210 ferredoxin--NADP reductase 0.52 UW163_RS08310 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodopseudomonas palustris CGA009 0.25 TX73_008105 ferredoxin--NADP reductase 0.33 TX73_016025 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Ralstonia solanacearum PSI07 0.25 RPSI07_RS17600 ferredoxin--NADP reductase 0.53 RPSI07_RS11985 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Variovorax sp. OAS795 0.24 ABID97_RS03500 ferredoxin--NADP reductase 0.40 ABID97_RS07435 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Sphingomonas koreensis DSMZ 15582 0.23 Ga0059261_3758 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.34 Ga0059261_0311 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Phaeobacter inhibens DSM 17395 0.22 PGA1_c20790 ferredoxin--NADP reductase Fpr 0.36 PGA1_c32050 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB — —
Caulobacter crescentus NA1000 0.21 CCNA_03314 ferredoxin-NADP reductase 0.31 CCNA_01723 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Caulobacter crescentus NA1000 Δfur 0.21 CCNA_03314 ferredoxin-NADP reductase 0.31 CCNA_01723 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Dinoroseobacter shibae DFL-12 0.21 Dshi_1150 Ferredoxin--NADP(+) reductase (RefSeq) 0.31 Dshi_2966 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS06545 ferredoxin--NADP reductase 0.28 A4249_RS03695 3-methyl-2-oxobutanoate hydroxymethyltransferase — —

Not shown: 1 genomes with orthologs for BWI76_RS27450 only; 17 genomes with orthologs for BWI76_RS04995 only