Conservation of cofitness between BPHYT_RS16440 and BPHYT_RS15305 in Burkholderia phytofirmans PsJN

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS16440 hemolysin D 1.0 BPHYT_RS15305 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.22 7
Paraburkholderia bryophila 376MFSha3.1 0.97 H281DRAFT_04221 hemolysin III 0.98 H281DRAFT_04004 (p)ppGpp synthetase I, SpoT/RelA low > 103
Paraburkholderia graminis OAS925 0.97 ABIE53_003461 hemolysin III 0.96 ABIE53_003230 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 113
Paraburkholderia sabiae LMG 24235 0.94 QEN71_RS02270 hemolysin III family protein 0.94 QEN71_RS03665 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 153
Acidovorax sp. GW101-3H11 0.62 Ac3H11_4296 COG1272: Predicted membrane protein hemolysin III homolog 0.53 Ac3H11_3664 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS02015 hemolysin III family protein 0.68 ABZR87_RS15225 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Cupriavidus basilensis FW507-4G11 0.62 RR42_RS36990 hemolysin III 0.68 RR42_RS04920 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Pseudomonas putida KT2440 0.61 PP_4986 Channel protein, hemolysin III family 0.45 PP_5302 bifunctional (p)ppGpp synthase/hydrolase
Pseudomonas sp. RS175 0.59 PFR28_04213 hypothetical protein 0.44 PFR28_04424 Bifunctional (p)ppGpp synthase/hydrolase SpoT
Pseudomonas fluorescens FW300-N2E2 0.59 Pf6N2E2_4629 COG1272: Predicted membrane protein hemolysin III homolog 0.44 Pf6N2E2_4361 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_1038 COG1272: Predicted membrane protein hemolysin III homolog 0.44 PfGW456L13_780 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas fluorescens FW300-N2E3 0.59 AO353_08075 hemolysin III 0.44 AO353_09280 (p)ppGpp synthetase
Pseudomonas stutzeri RCH2 0.59 Psest_3779 channel protein, hemolysin III family 0.43 Psest_3817 (p)ppGpp synthetase, RelA/SpoT family
Pseudomonas fluorescens FW300-N2C3 0.59 AO356_13560 hemolysin III 0.44 AO356_12480 (p)ppGpp synthetase
Pseudomonas simiae WCS417 0.58 PS417_26570 hemolysin III 0.45 PS417_27830 (p)ppGpp synthetase
Pseudomonas fluorescens SBW25 0.58 PFLU_RS28225 hemolysin III family protein 0.45 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Pseudomonas fluorescens SBW25-INTG 0.58 PFLU_RS28225 hemolysin III family protein 0.45 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.58 Psyr_0452 HylII 0.44 Psyr_0209 RelA/SpoT protein
Pseudomonas syringae pv. syringae B728a 0.58 Psyr_0452 HylII 0.44 Psyr_0209 RelA/SpoT protein
Pseudomonas fluorescens FW300-N1B4 0.58 Pf1N1B4_2371 COG1272: Predicted membrane protein hemolysin III homolog 0.44 Pf1N1B4_2113 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas sp. S08-1 0.57 OH686_06045 Predicted membrane protein, hemolysin III-related 0.44 OH686_13550 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase / GTP pyrophosphokinase , (p)ppGpp synthetase II low > 80
Xanthomonas campestris pv. campestris strain 8004 0.47 Xcc-8004.1589.1 COG1272: Predicted membrane protein hemolysin III homolog 0.40 Xcc-8004.1215.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Kangiella aquimarina DSM 16071 0.46 B158DRAFT_1582 channel protein, hemolysin III family 0.45 B158DRAFT_0574 (p)ppGpp synthetase, RelA/SpoT family
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_00950 Hemolysin D 0.41 OKGIIK_12100 spoT guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS06145 hemolysin III family protein 0.41 LRK54_RS11795 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Rhodanobacter denitrificans MT42 0.44 LRK55_RS05890 hemolysin III family protein 0.41 LRK55_RS11520 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Dyella japonica UNC79MFTsu3.2 0.44 ABZR86_RS18160 hemolysin III family protein 0.42 ABZR86_RS11850 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Lysobacter sp. OAE881 0.43 ABIE51_RS16230 hemolysin III family protein 0.40 ABIE51_RS17265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Marinobacter adhaerens HP15 0.43 HP15_2974 channel protein, hemolysin III family 0.42 HP15_305 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 73
Variovorax sp. OAS795 0.43 ABID97_RS07605 hemolysin III family protein 0.52 ABID97_RS23670 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Pantoea sp. MT58 0.41 IAI47_03795 hemolysin III family protein 0.41 IAI47_00510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 76
Serratia liquefaciens MT49 0.41 IAI46_20775 hemolysin III family protein 0.41 IAI46_24895 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 86
Enterobacter asburiae PDN3 0.40 EX28DRAFT_2950 channel protein, hemolysin III family 0.41 EX28DRAFT_3899 (p)ppGpp synthetase, RelA/SpoT family low > 76
Klebsiella michiganensis M5al 0.40 BWI76_RS23840 hemolysin III family protein 0.42 BWI76_RS27430 (p)ppGpp synthetase low > 92
Variovorax sp. SCN45 0.40 GFF5671 FIG01964566: Predicted membrane protein, hemolysin III homolog 0.52 GFF2375 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II
Enterobacter sp. TBS_079 0.40 MPMX20_03758 hypothetical protein 0.41 MPMX20_00086 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 85
Escherichia coli ECRC102 0.40 NIAGMN_17310 yqfA hemolysin III family protein 0.41 NIAGMN_13315 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli BL21 0.40 ECD_02731 hemolysin III family HylIII inner membrane protein 0.41 ECD_03507 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 61
Escherichia coli BW25113 0.40 b2899 yqfA predicted oxidoreductase, inner membrane subunit (NCBI) 0.41 b3650 spoT bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) low > 76
Escherichia coli ECRC99 0.40 KEDOAH_08595 yqfA hemolysin III family protein 0.41 KEDOAH_12590 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Rahnella sp. WP5 0.40 EX31_RS21610 hemolysin III family protein 0.41 EX31_RS15810 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 89
Escherichia coli ECRC98 0.40 JDDGAC_23185 yqfA hemolysin III family protein 0.41 JDDGAC_19180 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 86
Escherichia coli ECRC62 0.40 BNILDI_10000 yqfA hemolysin III family protein 0.41 BNILDI_04080 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Escherichia coli Nissle 1917 0.40 ECOLIN_RS16150 hemolysin III family protein 0.41 ECOLIN_RS20790 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 55
Escherichia coli ECRC101 0.40 MCAODC_10065 yqfA hemolysin III family protein 0.41 MCAODC_06065 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 87
Escherichia coli ECOR38 0.40 HEPCGN_18835 yqfA hemolysin III family protein 0.41 HEPCGN_14375 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 87
Escherichia fergusonii Becca 0.40 EFB2_01002 hypothetical protein 0.41 EFB2_00138 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.40 OHPLBJKB_00816 hypothetical protein 0.41 OHPLBJKB_00051 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 73
Escherichia coli ECOR27 0.40 NOLOHH_11465 yqfA hemolysin III family protein 0.41 NOLOHH_07435 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Escherichia coli ECRC100 0.40 OKFHMN_19545 yqfA hemolysin III family protein 0.41 OKFHMN_15555 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 80
Desulfovibrio vulgaris Miyazaki F 0.39 DvMF_2247 channel protein, hemolysin III family (RefSeq) 0.32 DvMF_0787 (p)ppGpp synthetase I, SpoT/RelA (RefSeq)
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.39 GFF2997 COG1272: Predicted membrane protein hemolysin III homolog 0.41 GFF357 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 low > 78
Dickeya dadantii 3937 0.38 DDA3937_RS03270 hemolysin III family protein 0.41 DDA3937_RS00180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Vibrio cholerae E7946 ATCC 55056 0.37 CSW01_00205 hemolysin III family protein 0.41 CSW01_13675 bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase low > 62
Dickeya dianthicola ME23 0.36 DZA65_RS03455 hemolysin III family protein 0.41 DZA65_RS22150 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Parabacteroides merdae CL09T00C40 0.36 HMPREF1078_RS01905 hemolysin III family protein 0.27 HMPREF1078_RS04420 RelA/SpoT family protein low > 61
Alteromonas macleodii MIT1002 0.36 MIT1002_00886 hemolysin 0.42 MIT1002_00108 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 70
Pectobacterium carotovorum WPP14 0.35 HER17_RS17935 hemolysin III family protein 0.41 HER17_RS21385 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Dickeya dianthicola 67-19 0.35 HGI48_RS03410 hemolysin III family protein 0.41 HGI48_RS21180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU3295 hemolysin III (TIGR) 0.33 DVU2083 relA GTP pyrophosphokinase (TIGR) 0.27 29
Shewanella loihica PV-4 0.31 Shew_2098 hemolysin III family channel protein (RefSeq) 0.43 Shew_3499 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.29 Sama_1862 hemolysin III family channel protein (RefSeq) 0.44 Sama_0264 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) low > 62
Shewanella sp. ANA-3 0.28 Shewana3_1934 hemolysin III family channel protein (RefSeq) 0.43 Shewana3_3812 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) low > 73
Bacteroides ovatus ATCC 8483 0.28 BACOVA_00687 hypothetical protein 0.26 BACOVA_04817 RelA/SpoT family protein
Shewanella oneidensis MR-1 0.27 SO2447 channel protein, hemolysin III family subfamily (NCBI ptt file) 0.44 SO0359 spoT guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) low > 76
Bacteroides thetaiotaomicron VPI-5482 0.27 BT1983 hemolysin III (NCBI ptt file) 0.26 BT3998 GTP pyrophosphokinase (NCBI ptt file)
Pedobacter sp. GW460-11-11-14-LB5 0.27 CA265_RS22915 hypothetical protein 0.28 CA265_RS14485 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 88
Sinorhizobium meliloti 1021 0.26 SMc00455 hypothetical protein 0.29 SMc02659 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein low > 103
Azospirillum brasilense Sp245 0.25 AZOBR_RS18955 DNA-binding protein 0.33 AZOBR_RS22045 GTP pyrophosphokinase low > 97
Rhodopseudomonas palustris CGA009 0.25 TX73_008140 hemolysin III family protein 0.29 TX73_013955 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 86
Azospirillum sp. SherDot2 0.24 MPMX19_02364 hypothetical protein 0.33 MPMX19_00838 GTP pyrophosphokinase rsh low > 112
Phocaeicola vulgatus CL09T03C04 0.24 HMPREF1058_RS00565 hemolysin III family protein 0.27 HMPREF1058_RS14060 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Agrobacterium fabrum C58 0.24 Atu0906 Hemolysin III 0.30 Atu1030 GTP pyrophosphohydrolase/synthetase, RelA/SpoT family low > 89
Phocaeicola dorei CL03T12C01 0.24 ABI39_RS08185 hemolysin III family protein 0.27 ABI39_RS09710 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Caulobacter crescentus NA1000 Δfur 0.23 CCNA_03601 hemolysin III-related membrane protein 0.29 CCNA_01622 Rsh ppGpp hydrolase-synthetase low > 67
Caulobacter crescentus NA1000 0.23 CCNA_03601 hemolysin III-related membrane protein 0.29 CCNA_01622 Rsh ppGpp hydrolase-synthetase low > 66
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS16820 hemolysin III family protein 0.26 HMPREF1181_RS09205 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Rhizobium sp. OAE497 0.23 ABIE40_RS04960 hemolysin III family protein 0.28 ABIE40_RS06050 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 107
Rhodospirillum rubrum S1H 0.22 Rru_A0661 Hly-III related proteins (NCBI) 0.31 Rru_A1856 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA (NCBI)
Dinoroseobacter shibae DFL-12 0.20 Dshi_2910 Hly-III family protein (RefSeq) 0.31 Dshi_0194 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) low > 64

Not shown: 2 genomes with orthologs for BPHYT_RS16440 only; 20 genomes with orthologs for BPHYT_RS15305 only