Conservation of cofitness between Atu3290 and Atu3784 in Agrobacterium fabrum C58

100 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu3290 phosphomethylpyrimidine kinase 1.0 Atu3784 glutamate synthase large subunit 0.77 16
Sinorhizobium meliloti 1021 0.59 SM_b20962 phoshomethylpyrimidine kinase 0.87 SMc04028 glutamate synthase low > 103
Xanthobacter sp. DMC5 0.55 GFF1029 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.72 GFF2524 Ferredoxin-dependent glutamate synthase 1 — —
Rhodopseudomonas palustris CGA009 0.53 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.69 TX73_004590 glutamate synthase large subunit — —
Enterobacter asburiae PDN3 0.51 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 EX28DRAFT_3275 Glutamate synthase domain 2 low > 76
Pectobacterium carotovorum WPP14 0.50 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 HER17_RS19910 glutamate synthase large subunit low > 75
Escherichia coli ECRC102 0.50 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 NIAGMN_15645 gltB glutamate synthase large subunit low > 80
Escherichia coli BW25113 0.50 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.38 b3212 gltB glutamate synthase, large subunit (NCBI) low > 76
Escherichia coli ECOR27 0.50 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 NOLOHH_09685 gltB glutamate synthase large subunit low > 76
Escherichia coli ECRC99 0.50 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 KEDOAH_10265 gltB glutamate synthase large subunit — —
Escherichia coli ECRC62 0.50 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 BNILDI_01850 gltB glutamate synthase large subunit low > 75
Escherichia coli ECRC101 0.50 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 MCAODC_08405 gltB glutamate synthase large subunit low > 87
Escherichia coli ECRC98 0.50 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 JDDGAC_21510 gltB glutamate synthase large subunit low > 87
Escherichia coli ECRC100 0.50 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 OKFHMN_17885 gltB glutamate synthase large subunit low > 79
Klebsiella michiganensis M5al 0.50 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 BWI76_RS25315 glutamate synthase large subunit low > 92
Escherichia coli HS(pFamp)R (ATCC 700891) 0.50 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.38 OHPLBJKB_00488 Glutamate synthase [NADPH] large chain low > 74
Escherichia fergusonii Becca 0.50 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.38 EFB2_00611 Glutamate synthase [NADPH] large chain low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.38 GFF2956 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 78
Enterobacter sp. TBS_079 0.50 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.38 MPMX20_04126 Glutamate synthase [NADPH] large chain low > 85
Escherichia coli ECOR38 0.50 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 HEPCGN_16760 gltB3 Glutamate synthase domain 3 0.67 34
Escherichia coli BL21 0.50 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase 0.38 ECD_03077 glutamate synthase, large subunit low > 61
Rahnella sp. WP5 0.50 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.39 EX31_RS12515 glutamate synthase large subunit low > 89
Serratia liquefaciens MT49 0.50 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.39 IAI46_22345 glutamate synthase large subunit low > 87
Erwinia tracheiphila HP pepo 2.2 0.50 IJEDHG_18705 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 IJEDHG_13705 gltB glutamate synthase large subunit low > 61
Erwinia tracheiphila SCR3 0.49 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 LU632_RS21315 gltB glutamate synthase large subunit low > 73
Klebsiella pneumoniae MKP103 0.49 KDGMDA_26425 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.39 KDGMDA_06145 glutamate synthase large subunit low > 95
Escherichia coli Nissle 1917 0.49 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 ECOLIN_RS18475 glutamate synthase large subunit — —
Dickeya dadantii 3937 0.49 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 DDA3937_RS01665 glutamate synthase large subunit 0.76 14
Bosea sp. OAE506 0.48 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.74 ABIE41_RS08565 glutamate synthase large subunit — —
Dickeya dianthicola 67-19 0.48 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 HGI48_RS01560 glutamate synthase large subunit 0.82 9
Dickeya dianthicola ME23 0.48 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 DZA65_RS01635 glutamate synthase large subunit 0.74 30
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.59 QEN71_RS28010 glutamate synthase-related protein — —
Paraburkholderia bryophila 376MFSha3.1 0.46 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase 0.60 H281DRAFT_05620 glutamate synthase (NADH) large subunit — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.45 Echvi_0215 phosphomethylpyrimidine kinase 0.47 Echvi_1244 Glutamate synthase domain 2 low > 79
Burkholderia phytofirmans PsJN 0.45 BPHYT_RS12250 phosphomethylpyrimidine kinase 0.59 BPHYT_RS17855 glutamate synthase — —
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.46 HMPREF1078_RS01270 glutamate synthase large subunit 0.37 3
Vibrio cholerae E7946 ATCC 55056 0.44 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.46 CSW01_12020 glutamate synthase large subunit low > 62
Bacteroides thetaiotaomicron VPI-5482 0.44 BT0790 phosphomethylpyrimidine kinase (NCBI ptt file) 0.45 BT0553 glutamate synthase, large subunit (NCBI ptt file) low > 81
Rhizobium sp. OAE497 0.43 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.89 ABIE40_RS16275 glutamate synthase large subunit — —
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS06820 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.46 HMPREF1058_RS06920 glutamate synthase large subunit low > 67
Phocaeicola dorei CL03T12C01 0.42 ABI39_RS20615 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.46 ABI39_RS20685 glutamate synthase large subunit low > 72
Dinoroseobacter shibae DFL-12 0.42 Dshi_0915 phosphomethylpyrimidine kinase (RefSeq) 0.37 Dshi_0002 Glutamate synthase (ferredoxin) (RefSeq) low > 64
Cellulophaga baltica 18 0.42 M666_RS03830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.48 M666_RS01740 glutamate synthase large subunit low > 67
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS14705 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.45 HMPREF1181_RS16055 glutamate synthase large subunit low > 56
Bacteroides ovatus ATCC 8483 0.42 BACOVA_02530 phosphomethylpyrimidine kinase 0.45 BACOVA_03756 class II glutamine amidotransferase low > 96
Castellaniella sp019104865 MT123 0.41 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.58 ABCV34_RS11150 glutamate synthase-related protein — —
Methylophilus sp. DMC18 0.41 GFF892 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.58 GFF2799 Ferredoxin-dependent glutamate synthase 1 — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.58 GFF1327 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 90
Pedobacter sp. GW460-11-11-14-LB5 0.40 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.50 CA265_RS08700 glutamate synthase large subunit low > 88
Acidovorax sp. GW101-3H11 0.39 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.58 Ac3H11_4710 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) — —
Rhodospirillum rubrum S1H 0.38 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) 0.39 Rru_A0019 Glutamate synthase (ferredoxin) (NCBI) — —
Rhodanobacter sp000427505 FW510-R12 0.38 LRK53_RS03825 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.58 LRK53_RS00070 glutamate synthase-related protein low > 59
Mucilaginibacter yixingensis YX-36 DSM 26809 0.36 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.49 ABZR88_RS06905 glutamate synthase large subunit low > 71
Bifidobacterium breve UCC2003 0.36 BBR_RS17215 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.44 BBR_RS15255 glutamate synthase large subunit low > 34
Dyella japonica UNC79MFTsu3.2 0.36 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.36 ABZR86_RS16795 glutamate synthase large subunit — —
Variovorax sp. OAS795 0.35 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.58 ABID97_RS23225 glutamate synthase-related protein — —
Ralstonia solanacearum UW163 0.35 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.60 UW163_RS06700 glutamate synthase subunit alpha — —
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.60 RALBFv3_RS06915 glutamate synthase subunit alpha — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.59 ABZR87_RS02570 glutamate synthase-related protein — —
Ralstonia solanacearum GMI1000 0.34 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.60 RS_RS14860 glutamate synthase subunit alpha — —
Caulobacter crescentus NA1000 Δfur 0.34 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.36 CCNA_03722 glutamate synthase (NADPH) large chain GltB — —
Caulobacter crescentus NA1000 0.34 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.36 CCNA_03722 glutamate synthase (NADPH) large chain GltB — —
Xanthomonas campestris pv. campestris strain 8004 0.34 Xcc-8004.3091.1 hypothetical protein 0.37 Xcc-8004.44.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.71 21
Ralstonia solanacearum PSI07 0.34 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.59 RPSI07_RS10320 glutamate synthase subunit alpha — —
Azospirillum sp. SherDot2 0.33 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.39 MPMX19_02657 Glutamate synthase [NADPH] large chain — —
Brevundimonas sp. GW460-12-10-14-LB2 0.33 A4249_RS15985 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.35 A4249_RS16105 glutamate synthase large subunit — —
Sphingobium sp. HT1-2 0.33 GFF2573 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.38 GFF765 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 95
Cupriavidus basilensis FW507-4G11 0.31 RR42_RS01370 phosphomethylpyrimidine kinase 0.58 RR42_RS18990 glutamate synthase — —
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_2379 thiD phosphomethylpyrimidine kinase 0.39 Synpcc7942_0890 glsF glutamate synthase (ferredoxin) — —
Magnetospirillum magneticum AMB-1 0.29 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 AMB_RS02685 glutamate synthase large subunit — —
Rhodanobacter sp. FW510-T8 0.29 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.58 OKGIIK_15200 Glutamate synthase subunit alpha low > 53
Acinetobacter radioresistens SK82 0.28 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 MPMX26_02808 Glutamate synthase [NADPH] large chain — —
Acinetobacter baumannii LAC-4 0.28 RR41_RS15160 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.38 RR41_RS01595 glutamate synthase large subunit — —
Pseudomonas aeruginosa MRSN321 0.27 DY961_RS12975 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.38 DY961_RS11000 gltB;go_function=catalytic glutamate synthase large subunit low > 100
Pseudomonas aeruginosa PA14 0.27 IKLFDK_20515 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.37 IKLFDK_28355 glutamate synthase large subunit 0.63 59
Pseudomonas aeruginosa PUPa3 0.27 DQ20_RS48300 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 DQ20_RS51075 gltB;go_function=catalytic glutamate synthase large subunit low > 101
Dechlorosoma suillum PS 0.27 Dsui_0662 phosphomethylpyrimidine kinase 0.61 Dsui_1096 glutamate synthase family protein — —
Sphingomonas koreensis DSMZ 15582 0.27 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 Ga0059261_1800 Glutamate synthase domain 2 — —
Pseudomonas simiae WCS417 0.27 PS417_24600 hydrogenase 0.37 PS417_02000 glutamate synthase low > 88
Pseudomonas sp. BP01 0.27 JOY50_RS21745 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 JOY50_RS09320 gltB glutamate synthase large subunit low > 84
Pseudomonas fluorescens FW300-N2C3 0.27 AO356_15435 hydrogenase 0.37 AO356_09375 glutamate synthase low > 104
Pseudomonas putida KT2440 0.27 PP_4782 Phosphomethylpyrimidine kinase 0.37 PP_5076 L-glutamate synthase(NADPH) alpha subunit low > 96
Pseudomonas sp. SVBP6 0.26 COO64_RS15485 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 COO64_RS13085 gltB glutamate synthase large subunit 0.81 1
Pseudomonas orientalis W4I3 0.26 QF045_RS26885 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 QF045_RS05060 glutamate synthase large subunit low > 93
Pseudomonas fluorescens FW300-N2E3 0.26 AO353_06350 hydrogenase 0.37 AO353_12515 glutamate synthase low > 101
Pseudomonas sp. S08-1 0.26 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD 0.38 OH686_10005 Glutamate synthase [NADPH] large chain low > 80
Pseudomonas fluorescens SBW25 0.26 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 PFLU_RS02045 glutamate synthase large subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 PFLU_RS02045 glutamate synthase large subunit low > 109
Mycobacterium tuberculosis H37Rv 0.26 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) 0.46 Rv3859c Probable ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate synthase) (glutamate synthase (NADH))(NADPH-GOGAT) — —
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.37 PfGW456L13_272 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 87
Pseudomonas sp. DMC3 0.26 GFF3905 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 GFF3102 Glutamate synthase [NADPH] large chain low > 89
Pseudomonas syringae pv. syringae B728a ΔmexB 0.26 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.37 Psyr_0411 glutamate synthase (NADPH) large subunit low > 86
Pseudomonas stutzeri RCH2 0.26 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 Psest_3711 Glutamate synthase domain 2 low > 67
Pseudomonas syringae pv. syringae B728a 0.26 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.37 Psyr_0411 glutamate synthase (NADPH) large subunit low > 86
Pseudomonas segetis P6 0.25 MPMX49_01077 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 MPMX49_04231 Glutamate synthase [NADPH] large chain low > 75
Pseudomonas sp. RS175 0.24 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 PFR28_05015 Glutamate synthase [NADPH] large chain low > 88
Herbaspirillum seropedicae SmR1 0.24 HSERO_RS02135 phosphomethylpyrimidine kinase 0.60 HSERO_RS19595 glutamate synthase 0.44 15
Pseudomonas fluorescens FW300-N2E2 0.23 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.37 Pf6N2E2_3752 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 103
Pseudomonas fluorescens FW300-N1B4 0.23 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.36 Pf1N1B4_1534 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 87
Pseudomonas lactucae CFBP13502 0.23 GEMAOFIL_05068 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.37 GEMAOFIL_00632 Glutamate synthase [NADPH] large chain low > 96
Phaeobacter inhibens DSM 17395 0.19 PGA1_c09030 phosphomethylpyrimidine kinase ThiD 0.37 PGA1_c36100 glutamate synthase [NADPH] large chain low > 62

Not shown: 10 genomes with orthologs for Atu3290 only; 10 genomes with orthologs for Atu3784 only