| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Ralstonia sp. UNC404CL21Col | 1.0 | ABZR87_RS15265 | | radical SAM family heme chaperone HemW | 1.0 | ABZR87_RS04880 | | 5-formyltetrahydrofolate cyclo-ligase | 0.59 | 17 |
| Ralstonia solanacearum PSI07 | 0.94 | RPSI07_RS13830 | | oxygen-independent coproporphyrinogen III oxidase-like protein | 0.85 | RPSI07_RS23505 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 81 |
| Ralstonia solanacearum IBSBF1503 | 0.90 | RALBFv3_RS03355 | | oxygen-independent coproporphyrinogen III oxidase-like protein | 0.86 | RALBFv3_RS09865 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 76 |
| Ralstonia solanacearum UW163 | 0.90 | UW163_RS10365 | | oxygen-independent coproporphyrinogen III oxidase-like protein | 0.86 | UW163_RS03715 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Ralstonia solanacearum GMI1000 | 0.89 | RS_RS10840 | | oxygen-independent coproporphyrinogen III oxidase-like protein | 0.84 | RS_RS00450 | | 5-formyltetrahydrofolate cyclo-ligase | 0.26 | 63 |
| Cupriavidus basilensis FW507-4G11 | 0.69 | RR42_RS04880 | | coproporphyrinogen III oxidase | 0.38 | RR42_RS01400 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 128 |
| Paraburkholderia graminis OAS925 | 0.66 | ABIE53_003236 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.33 | ABIE53_000045 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 113 |
| Burkholderia phytofirmans PsJN | 0.66 | BPHYT_RS15335 | | coproporphyrinogen III oxidase | 0.33 | BPHYT_RS18615 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 109 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.66 | H281DRAFT_04010 | | oxygen-independent coproporphyrinogen-3 oxidase | 0.32 | H281DRAFT_05815 | | 5,10-methenyltetrahydrofolate synthetase | low | > 103 |
| Paraburkholderia sabiae LMG 24235 | 0.66 | QEN71_RS03635 | | radical SAM family heme chaperone HemW | 0.34 | QEN71_RS28640 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 153 |
| Herbaspirillum seropedicae SmR1 | 0.63 | HSERO_RS10665 | | coproporphyrinogen III oxidase | 0.26 | HSERO_RS21420 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 78 |
| Variovorax sp. SCN45 | 0.56 | GFF2383 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW | 0.28 | GFF5164 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | low | > 127 |
| Variovorax sp. OAS795 | 0.55 | ABID97_RS23630 | | radical SAM family heme chaperone HemW | 0.27 | ABID97_RS06600 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 91 |
| Castellaniella sp019104865 MT123 | 0.52 | ABCV34_RS03525 | | radical SAM family heme chaperone HemW | 0.29 | ABCV34_RS13555 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Dechlorosoma suillum PS | 0.52 | Dsui_0491 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.25 | Dsui_0682 | | 5,10-methenyltetrahydrofolate synthetase | — | — |
| Lysobacter sp. OAE881 | 0.46 | ABIE51_RS17300 | | radical SAM family heme chaperone HemW | 0.19 | ABIE51_RS17355 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 62 |
| Kangiella aquimarina DSM 16071 | 0.46 | B158DRAFT_0201 | | coproporphyrinogen III oxidase, anaerobic (EC 1.3.99.22) | 0.16 | B158DRAFT_0528 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 40 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.45 | Xcc-8004.1224.1 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.17 | Xcc-8004.1138.1 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | low | > 74 |
| Pseudomonas simiae WCS417 | 0.45 | PS417_26760 | | oxidase | 0.16 | PS417_27305 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 88 |
| Rhodanobacter denitrificans MT42 | 0.45 | LRK55_RS11460 | | radical SAM family heme chaperone HemW | 0.22 | LRK55_RS11395 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.45 | LRK54_RS11735 | | radical SAM family heme chaperone HemW | 0.21 | LRK54_RS11670 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 59 |
| Pseudomonas fluorescens SBW25 | 0.45 | PFLU_RS28405 | | radical SAM family heme chaperone HemW | 0.16 | PFLU_RS28965 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.45 | PFLU_RS28405 | | radical SAM family heme chaperone HemW | 0.16 | PFLU_RS28965 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 109 |
| Dyella japonica UNC79MFTsu3.2 | 0.44 | ABZR86_RS11910 | | radical SAM family heme chaperone HemW | 0.19 | ABZR86_RS11995 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 74 |
| Pseudomonas fluorescens FW300-N2E2 | 0.44 | Pf6N2E2_4593 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.17 | Pf6N2E2_4476 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | low | > 103 |
| Pseudomonas fluorescens FW300-N2E3 | 0.44 | AO353_08200 | | coproporphyrinogen III oxidase | 0.17 | AO353_08780 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 101 |
| Pseudomonas fluorescens FW300-N1B4 | 0.44 | Pf1N1B4_2334 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.16 | Pf1N1B4_2225 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | low | > 87 |
| Pseudomonas sp. S08-1 | 0.44 | OH686_11020 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW | 0.15 | OH686_11225 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 80 |
| Pseudomonas fluorescens GW456-L13 | 0.44 | PfGW456L13_1003 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.15 | PfGW456L13_892 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | low | > 87 |
| Pseudomonas fluorescens FW300-N2C3 | 0.43 | AO356_13390 | | coproporphyrinogen III oxidase | 0.16 | AO356_12990 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 104 |
| Rhodanobacter sp. FW510-T8 | 0.43 | OKGIIK_12160 | hemW | radical SAM family heme chaperone HemW | 0.22 | OKGIIK_12225 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 52 |
| Pseudomonas sp. RS175 | 0.43 | PFR28_04249 | | Heme chaperone HemW | 0.14 | PFR28_04325 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 88 |
| Enterobacter sp. TBS_079 | 0.43 | MPMX20_03813 | | Heme chaperone HemW | 0.14 | MPMX20_03770 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 85 |
| Pseudomonas putida KT2440 | 0.43 | PP_5101 | | coproporphyrinogen/heterocyclic compound oxidase (aerobic) | 0.15 | PP_5203 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 96 |
| Serratia liquefaciens MT49 | 0.43 | IAI46_21435 | | radical SAM family heme chaperone HemW | 0.15 | IAI46_20895 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.43 | Psyr_0471 | | coproporphyrinogen III oxidase, anaerobic | 0.15 | Psyr_0317 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.43 | Psyr_0471 | | coproporphyrinogen III oxidase, anaerobic | 0.15 | Psyr_0317 | | 5-formyltetrahydrofolate cyclo-ligase | 0.30 | 63 |
| Shewanella oneidensis MR-1 | 0.42 | SO3359 | | oxygen-independent coproporphyrinogen III oxidase, putative (NCBI ptt file) | 0.15 | SO0774 | | 5-formyltetrahydrofolate cyclo-ligase family protein (NCBI ptt file) | low | > 76 |
| Pectobacterium carotovorum WPP14 | 0.42 | HER17_RS03785 | | radical SAM family heme chaperone HemW | 0.16 | HER17_RS19095 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 75 |
| Enterobacter asburiae PDN3 | 0.42 | EX28DRAFT_2993 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.14 | EX28DRAFT_2964 | | 5,10-methenyltetrahydrofolate synthetase | low | > 76 |
| Escherichia coli ECOR38 | 0.42 | HEPCGN_18540 | hemW | radical SAM family heme chaperone HemW | 0.13 | HEPCGN_18775 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | low | > 87 |
| Klebsiella michiganensis M5al | 0.42 | BWI76_RS24120 | | YggW family oxidoreductase | 0.13 | BWI76_RS23915 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 92 |
| Escherichia fergusonii Becca | 0.42 | EFB2_00947 | | Heme chaperone HemW | 0.14 | EFB2_00991 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 86 |
| Dickeya dadantii 3937 | 0.42 | DDA3937_RS17325 | | radical SAM family heme chaperone HemW | 0.16 | DDA3937_RS02410 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 74 |
| Pseudomonas stutzeri RCH2 | 0.42 | Psest_0276 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.16 | Psest_0170 | | 5,10-methenyltetrahydrofolate synthetase | low | > 67 |
| Escherichia coli ECRC99 | 0.42 | KEDOAH_08905 | hemW | radical SAM family heme chaperone HemW | 0.14 | KEDOAH_08655 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Shewanella sp. ANA-3 | 0.42 | Shewana3_1188 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | 0.18 | Shewana3_3506 | | 5-formyltetrahydrofolate cyclo-ligase (RefSeq) | low | > 73 |
| Escherichia coli ECRC101 | 0.42 | MCAODC_09755 | hemW | radical SAM family heme chaperone HemW | 0.14 | MCAODC_10005 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | low | > 87 |
| Escherichia coli ECRC102 | 0.42 | NIAGMN_17000 | hemW | radical SAM family heme chaperone HemW | 0.14 | NIAGMN_17250 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Escherichia coli Nissle 1917 | 0.42 | ECOLIN_RS16435 | | radical SAM family heme chaperone HemW | 0.13 | ECOLIN_RS16205 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 55 |
| Escherichia coli ECRC98 | 0.42 | JDDGAC_22865 | hemW | radical SAM family heme chaperone HemW | 0.14 | JDDGAC_23125 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | low | > 86 |
| Escherichia coli ECRC100 | 0.42 | OKFHMN_19235 | hemW | radical SAM family heme chaperone HemW | 0.14 | OKFHMN_19485 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | low | > 80 |
| Erwinia tracheiphila SCR3 | 0.42 | LU632_RS05445 | hemW | radical SAM family heme chaperone HemW | 0.16 | LU632_RS05860 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Escherichia coli ECRC62 | 0.41 | BNILDI_09685 | hemW | radical SAM family heme chaperone HemW | 0.14 | BNILDI_09930 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | low | > 75 |
| Rahnella sp. WP5 | 0.41 | EX31_RS02710 | | radical SAM family heme chaperone HemW | 0.15 | EX31_RS21480 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 89 |
| Escherichia coli ECOR27 | 0.41 | NOLOHH_11105 | hemW | radical SAM family heme chaperone HemW | 0.14 | NOLOHH_11395 | ygfA | 5-formyltetrahydrofolate cyclo-ligase | low | > 75 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.41 | GFF3058 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.14 | GFF3012 | | 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | low | > 78 |
| Pantoea sp. MT58 | 0.41 | IAI47_03580 | | radical SAM family heme chaperone HemW | 0.15 | IAI47_03730 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 76 |
| Vibrio cholerae E7946 ATCC 55056 | 0.41 | CSW01_02425 | | YggW family oxidoreductase | 0.16 | CSW01_12545 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 62 |
| Shewanella loihica PV-4 | 0.40 | Shew_1131 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | 0.18 | Shew_3069 | | 5-formyltetrahydrofolate cyclo-ligase (RefSeq) | low | > 60 |
| Marinobacter adhaerens HP15 | 0.37 | HP15_280 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.13 | HP15_3211 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 73 |
| Dinoroseobacter shibae DFL-12 | 0.31 | Dshi_3460 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | 0.21 | Dshi_2769 | | 5-formyltetrahydrofolate cyclo-ligase (RefSeq) | low | > 64 |
| Rhodopseudomonas palustris CGA009 | 0.30 | TX73_001700 | | radical SAM family heme chaperone HemW | 0.23 | TX73_023120 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Azospirillum sp. SherDot2 | 0.30 | MPMX19_02574 | | Heme chaperone HemW | 0.17 | MPMX19_00693 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 112 |
| Agrobacterium fabrum C58 | 0.30 | Atu0325 | | oxygen-independent coproporphyrinogen III oxidase | 0.21 | Atu3731 | | 5-formyltetrahydrofolate cyclo-ligase | — | — |
| Azospirillum brasilense Sp245 | 0.29 | AZOBR_RS02195 | | coproporphyrinogen III oxidase | 0.22 | AZOBR_RS09025 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 97 |
| Bosea sp. OAE506 | 0.29 | ABIE41_RS03305 | | radical SAM family heme chaperone HemW | 0.20 | ABIE41_RS09445 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 77 |
| Magnetospirillum magneticum AMB-1 | 0.26 | AMB_RS22770 | | radical SAM protein | 0.23 | AMB_RS16280 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 64 |
| Caulobacter crescentus NA1000 | 0.24 | CCNA_00144 | | oxygen-independent coproporphyrinogen-III oxidase | 0.18 | CCNA_03354 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.24 | CCNA_00144 | | oxygen-independent coproporphyrinogen-III oxidase | 0.18 | CCNA_03354 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 67 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.23 | CA264_16765 | | coproporphyrinogen III oxidase | 0.12 | CA264_15880 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 74 |
| Phocaeicola vulgatus CL09T03C04 | 0.22 | HMPREF1058_RS07680 | | radical SAM family heme chaperone HemW | 0.14 | HMPREF1058_RS17145 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 67 |
| Desulfovibrio vulgaris Miyazaki F | 0.22 | DvMF_2374 | | oxygen-independent coproporphyrinogen III oxidase (RefSeq) | 0.13 | DvMF_2318 | | 5-formyltetrahydrofolate cyclo-ligase (RefSeq) | low | > 51 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.21 | CA265_RS18155 | | coproporphyrinogen III oxidase | 0.14 | CA265_RS21460 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 88 |
| Phocaeicola dorei CL03T12C01 | 0.21 | ABI39_RS00100 | | radical SAM family heme chaperone HemW | 0.14 | ABI39_RS13145 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 72 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.21 | BT2168 | | coproporphyrinogen III oxidase (NCBI ptt file) | 0.14 | BT4258 | | putative 5-formyltetrahydrofolate cyclo-ligase (NCBI ptt file) | low | > 81 |
| Parabacteroides merdae CL09T00C40 | 0.20 | HMPREF1078_RS11035 | | radical SAM family heme chaperone HemW | 0.15 | HMPREF1078_RS14635 | | 5-formyltetrahydrofolate cyclo-ligase | low | > 61 |
Not shown: 14 genomes with orthologs for ABZR87_RS15265 only; 3 genomes with orthologs for ABZR87_RS04880 only