Conservation of cofitness between b0109 and b2574 in Escherichia coli BW25113

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0109 nadC nicotinate-nucleotide pyrophosphorylase (NCBI) 1.0 b2574 nadB L-aspartate oxidase (NCBI) 0.87 2
Escherichia coli BL21 1.00 ECD_00108 quinolinate phosphoribosyltransferase 0.99 ECD_02468 quinolinate synthase, L-aspartate oxidase (B protein) subunit low > 60
Escherichia coli ECOR27 1.00 NOLOHH_02875 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.99 NOLOHH_13045 nadB L-aspartate oxidase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03552 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 1.00 OHPLBJKB_01133 L-aspartate oxidase low > 73
Escherichia coli ECRC99 1.00 KEDOAH_17625 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.99 KEDOAH_06850 nadB L-aspartate oxidase — —
Escherichia coli ECRC102 1.00 NIAGMN_08380 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.99 NIAGMN_19140 nadB L-aspartate oxidase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS00585 carboxylating nicotinate-nucleotide diphosphorylase 0.98 ECOLIN_RS14570 L-aspartate oxidase low > 52
Escherichia coli ECRC101 1.00 MCAODC_01045 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.99 MCAODC_11900 nadB L-aspartate oxidase — —
Escherichia coli ECRC98 1.00 JDDGAC_14125 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.99 JDDGAC_25035 nadB L-aspartate oxidase — —
Escherichia fergusonii Becca 1.00 EFB2_03940 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.98 EFB2_01322 L-aspartate oxidase low > 86
Escherichia coli ECRC101 1.00 OKFHMN_10530 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.99 OKFHMN_21370 nadB L-aspartate oxidase — —
Escherichia coli ECRC62 1.00 BNILDI_08735 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.99 BNILDI_11845 nadB L-aspartate oxidase — —
Escherichia coli ECOR38 0.99 HEPCGN_08510 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.99 HEPCGN_20515 nadB L-aspartate oxidase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.87 GFF130 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.91 GFF2106 L-aspartate oxidase (EC 1.4.3.16) low > 78
Klebsiella michiganensis M5al 0.81 BWI76_RS04845 nicotinate-nucleotide pyrophosphorylase 0.89 BWI76_RS21360 L-aspartate oxidase 0.89 1
Enterobacter sp. TBS_079 0.81 MPMX20_00800 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.91 MPMX20_03445 L-aspartate oxidase 0.71 1
Enterobacter asburiae PDN3 0.81 EX28DRAFT_3702 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.91 EX28DRAFT_0071 L-aspartate oxidase (EC 1.4.3.16) 0.73 5
Rahnella sp. WP5 0.74 EX31_RS03515 carboxylating nicotinate-nucleotide diphosphorylase 0.81 EX31_RS21795 L-aspartate oxidase 0.77 1
Serratia liquefaciens MT49 0.71 IAI46_03530 carboxylating nicotinate-nucleotide diphosphorylase 0.82 IAI46_19590 L-aspartate oxidase low > 86
Pectobacterium carotovorum WPP14 0.69 HER17_RS03250 carboxylating nicotinate-nucleotide diphosphorylase 0.83 HER17_RS05775 L-aspartate oxidase 0.99 1
Pantoea sp. MT58 0.69 IAI47_15845 carboxylating nicotinate-nucleotide diphosphorylase 0.81 IAI47_04845 L-aspartate oxidase 0.78 2
Dickeya dadantii 3937 0.67 DDA3937_RS17955 carboxylating nicotinate-nucleotide diphosphorylase 0.80 DDA3937_RS15770 L-aspartate oxidase 0.97 1
Dickeya dianthicola ME23 0.66 DZA65_RS19035 carboxylating nicotinate-nucleotide diphosphorylase 0.80 DZA65_RS16935 L-aspartate oxidase 0.97 1
Dickeya dianthicola 67-19 0.66 HGI48_RS17890 carboxylating nicotinate-nucleotide diphosphorylase 0.80 HGI48_RS15855 L-aspartate oxidase 0.62 20
Shewanella amazonensis SB2B 0.58 Sama_0371 nicotinate-nucleotide diphosphorylase (carboxylating) (RefSeq) 0.73 Sama_0873 L-aspartate oxidase (RefSeq) — —
Vibrio cholerae E7946 ATCC 55056 0.58 CSW01_12265 carboxylating nicotinate-nucleotide diphosphorylase 0.75 CSW01_12495 L-aspartate oxidase low > 62
Shewanella sp. ANA-3 0.55 Shewana3_0422 nicotinate-nucleotide pyrophosphorylase [carboxylating] (RefSeq) 0.72 Shewana3_3033 L-aspartate oxidase (RefSeq) — —
Shewanella loihica PV-4 0.54 Shew_3435 nicotinate-nucleotide pyrophosphorylase (RefSeq) 0.72 Shew_1047 L-aspartate oxidase (RefSeq) — —
Alteromonas macleodii MIT1002 0.52 MIT1002_03008 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.70 MIT1002_02720 L-aspartate oxidase — —
Pseudomonas stutzeri RCH2 0.52 Psest_0718 nicotinate-nucleotide pyrophosphorylase 0.63 Psest_3101 L-aspartate oxidase 0.37 54
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.62 Psyr_3959 L-aspartate oxidase 0.74 5
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.62 Psyr_3959 L-aspartate oxidase low > 86
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_05520 nicotinate-nucleotide pyrophosphorylase 0.63 AO353_17620 L-aspartate oxidase 0.79 2
Pseudomonas sp. RS175 0.50 PFR28_00098 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.62 PFR28_00689 L-aspartate oxidase 0.73 2
Pseudomonas putida KT2440 0.49 PP_0787 quinolinate phosphoribosyltransferase (decarboxylating) monomer 0.63 PP_1426 L-aspartate oxidase 0.62 29
Pseudomonas fluorescens SBW25-INTG 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.63 PFLU_RS07225 L-aspartate oxidase 0.64 2
Pseudomonas fluorescens SBW25 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.63 PFLU_RS07225 L-aspartate oxidase low > 109
Kangiella aquimarina DSM 16071 0.49 B158DRAFT_2135 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.65 B158DRAFT_2179 L-aspartate oxidase (EC 1.4.3.16) — —
Acinetobacter radioresistens SK82 0.49 MPMX26_00042 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.59 MPMX26_02162 L-aspartate oxidase 0.71 2
Pseudomonas fluorescens FW300-N1B4 0.48 Pf1N1B4_1153 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.62 Pf1N1B4_3322 L-aspartate oxidase (EC 1.4.3.16) 0.56 3
Marinobacter adhaerens HP15 0.48 HP15_1305 nicotinate-nucleotide pyrophosphorylase 0.59 HP15_774 L-aspartate oxidase — —
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_3346 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.60 Pf6N2E2_2758 L-aspartate oxidase (EC 1.4.3.16) 0.69 2
Pseudomonas simiae WCS417 0.48 PS417_03925 nicotinate-nucleotide pyrophosphorylase 0.62 PS417_07115 L-aspartate oxidase 0.77 2
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_07370 nicotinate-nucleotide pyrophosphorylase 0.62 AO356_04580 L-aspartate oxidase low > 104
Pseudomonas sp. S08-1 0.48 OH686_16520 nicotinate-nucleotide diphosphorylase (carboxylating) 0.62 OH686_20040 L-aspartate oxidase 0.68 28
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_5082 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.62 PfGW456L13_4517 L-aspartate oxidase (EC 1.4.3.16) 0.72 4
Dechlorosoma suillum PS 0.44 Dsui_2901 nicotinate-nucleotide pyrophosphorylase 0.57 Dsui_2452 L-aspartate oxidase — —
Ralstonia solanacearum PSI07 0.42 RPSI07_RS12655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.58 RPSI07_RS12660 L-aspartate oxidase low > 81
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF1217 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.55 GFF1214 L-aspartate oxidase (EC 1.4.3.16) 0.49 34
Ralstonia sp. UNC404CL21Col 0.41 ABZR87_RS00350 carboxylating nicotinate-nucleotide diphosphorylase 0.58 ABZR87_RS00345 L-aspartate oxidase 0.91 2
Ralstonia solanacearum UW163 0.41 UW163_RS08940 nicotinate-nucleotide diphosphorylase (carboxylating) 0.58 UW163_RS08945 L-aspartate oxidase — —
Ralstonia solanacearum IBSBF1503 0.41 RALBFv3_RS04730 nicotinate-nucleotide diphosphorylase (carboxylating) 0.58 RALBFv3_RS04725 L-aspartate oxidase low > 76
Acidovorax sp. GW101-3H11 0.40 Ac3H11_3838 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.53 Ac3H11_3824 L-aspartate oxidase (EC 1.4.3.16) 0.85 5
Herbaspirillum seropedicae SmR1 0.40 HSERO_RS11070 nicotinate-nucleotide pyrophosphorylase 0.56 HSERO_RS11085 L-aspartate oxidase 0.87 2
Cupriavidus basilensis FW507-4G11 0.40 RR42_RS17015 nicotinate-nucleotide pyrophosphorylase 0.58 RR42_RS17010 L-aspartate oxidase low > 128
Castellaniella sp019104865 MT123 0.39 ABCV34_RS03695 carboxylating nicotinate-nucleotide diphosphorylase 0.51 ABCV34_RS03690 L-aspartate oxidase low > 48
Paraburkholderia graminis OAS925 0.39 ABIE53_003293 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.58 ABIE53_003292 L-aspartate oxidase 0.86 2
Ralstonia solanacearum GMI1000 0.39 RS_RS12290 nicotinate-nucleotide diphosphorylase (carboxylating) 0.58 RS_RS12285 L-aspartate oxidase low > 80
Variovorax sp. OAS795 0.39 ABID97_RS07410 carboxylating nicotinate-nucleotide diphosphorylase 0.53 ABID97_RS07440 L-aspartate oxidase 0.91 2
Burkholderia phytofirmans PsJN 0.38 BPHYT_RS15645 nicotinate-nucleotide pyrophosphorylase 0.57 BPHYT_RS15640 L-aspartate oxidase 0.93 2
Paraburkholderia sabiae LMG 24235 0.38 QEN71_RS03065 carboxylating nicotinate-nucleotide diphosphorylase 0.57 QEN71_RS03070 L-aspartate oxidase 0.94 2
Paraburkholderia bryophila 376MFSha3.1 0.38 H281DRAFT_04070 nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.58 H281DRAFT_04069 L-aspartate oxidase 0.91 1
Variovorax sp. SCN45 0.36 GFF2574 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.55 GFF2580 L-aspartate oxidase (EC 1.4.3.16) 0.54 41
Rhodopseudomonas palustris CGA009 0.35 TX73_005415 carboxylating nicotinate-nucleotide diphosphorylase 0.25 TX73_005420 L-aspartate oxidase — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS19655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.56 AMB_RS19650 L-aspartate oxidase — —
Rhizobium sp. OAE497 0.33 ABIE40_RS23265 carboxylating nicotinate-nucleotide diphosphorylase 0.22 ABIE40_RS23260 L-aspartate oxidase 0.59 13
Rhodospirillum rubrum S1H 0.33 Rru_A1432 Nicotinate-nucleotide pyrophosphorylase (NCBI) 0.25 Rru_A1433 L-aspartate oxidase (NCBI) 0.86 9
Brevundimonas sp. GW460-12-10-14-LB2 0.33 A4249_RS00635 carboxylating nicotinate-nucleotide diphosphorylase 0.20 A4249_RS00630 L-aspartate oxidase low > 48
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.20 CCNA_03007 L-aspartate oxidase — —
Caulobacter crescentus NA1000 0.33 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.20 CCNA_03007 L-aspartate oxidase — —
Parabacteroides merdae CL09T00C40 0.32 HMPREF1078_RS16725 carboxylating nicotinate-nucleotide diphosphorylase 0.42 HMPREF1078_RS06605 L-aspartate oxidase — —
Mycobacterium tuberculosis H37Rv 0.32 Rv1596 Probable nicotinate-nucleotide pyrophosphatase NadC 0.24 Rv1595 Probable L-aspartate oxidase NadB — —
Agrobacterium fabrum C58 0.32 Atu4096 nicotinate-nucleotide pyrophosphorylase 0.23 Atu4097 L-aspartate oxidase 0.94 2
Azospirillum sp. SherDot2 0.31 MPMX19_05672 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.27 MPMX19_05671 L-aspartate oxidase — —
Pedobacter sp. GW460-11-11-14-LB5 0.31 CA265_RS14530 nicotinate-nucleotide diphosphorylase (carboxylating) 0.43 CA265_RS21185 L-aspartate oxidase 0.64 1
Mucilaginibacter yixingensis YX-36 DSM 26809 0.31 ABZR88_RS15695 carboxylating nicotinate-nucleotide diphosphorylase 0.43 ABZR88_RS20645 L-aspartate oxidase — —
Bacteroides ovatus ATCC 8483 0.31 BACOVA_04303 nicotinate-nucleotide diphosphorylase (carboxylating) 0.41 BACOVA_02888 L-aspartate oxidase 0.83 41
Bacteroides stercoris CC31F 0.30 HMPREF1181_RS10745 carboxylating nicotinate-nucleotide diphosphorylase 0.41 HMPREF1181_RS01800 L-aspartate oxidase — —
Bacteroides thetaiotaomicron VPI-5482 0.30 BT1560 nicotinate-nucleotide pyrophosphorylase (NCBI ptt file) 0.42 BT3184 L-aspartate oxidase (NCBI ptt file) — —
Bifidobacterium breve UCC2003 0.30 BBR_RS16720 nicotinate-nucleotide diphosphorylase (carboxylating) 0.27 BBR_RS16725 L-aspartate oxidase 0.20 2
Phocaeicola dorei CL03T12C01 0.30 ABI39_RS11900 carboxylating nicotinate-nucleotide diphosphorylase 0.42 ABI39_RS05945 L-aspartate oxidase — —
Phocaeicola vulgatus CL09T03C04 0.30 HMPREF1058_RS15940 carboxylating nicotinate-nucleotide diphosphorylase 0.42 HMPREF1058_RS11085 L-aspartate oxidase — —
Sphingomonas koreensis DSMZ 15582 0.29 Ga0059261_0061 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.52 Ga0059261_2248 L-aspartate oxidase (EC 1.4.3.16) — —
Phaeobacter inhibens DSM 17395 0.28 PGA1_c27810 nicotinate-nucleotide pyrophosphorylase 0.22 PGA1_c27800 L-aspartate oxidase NadB 0.73 2
Synechococcus elongatus PCC 7942 0.27 Synpcc7942_0951 nadC nicotinate-nucleotide pyrophosphorylase 0.32 Synpcc7942_1881 nadB L-aspartate oxidase 0.63 5
Sinorhizobium meliloti 1021 0.25 SMc02598 nicotinate-nucleotide pyrophosphorylase carboxylating protein 0.29 SMc02599 L-aspartate oxidase 0.21 26

Not shown: 12 genomes with orthologs for b0109 only; 4 genomes with orthologs for b2574 only