| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
|---|
| | Methanococcus maripaludis JJ | MMJJ_RS04790 | | biotin--[acetyl-CoA-carboxylase] ligase | strong | 100 | 100 |
| o | Methanococcus maripaludis S2 | MMP_RS00695 | | biotin--[acetyl-CoA-carboxylase] ligase | sig. | 95 | 96 |
| | Pseudomonas sp. SVBP6 | COO64_RS16330 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | insig. | 32 | 78 |
| | Pseudomonas putida KT2440 | PP_0437 | | bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 29 | 78 |
| | Cellulophaga baltica 18 | M666_RS08960 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 36 | 69 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_07105 | | biotin--protein ligase | insig. | 28 | 93 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_22055 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 57 |
| | Pseudomonas sp. BP01 | JOY50_RS20490 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 34 | 59 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1238 | | Biotin operon repressor / Biotin-protein ligase (EC 6.3.4.15) | sig. | 35 | 59 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_4564 | | Biotin--acetyl-CoA-carboxylase ligase | insig. | 34 | 59 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_4564 | | Biotin--acetyl-CoA-carboxylase ligase | sig. | 34 | 59 |
| | Pseudomonas simiae WCS417 | PS417_25635 | | biotin--protein ligase | sig. | 37 | 56 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2565 | | Biotin operon repressor / Biotin-protein ligase (EC 6.3.4.15) | no data | 32 | 62 |
| | Pseudomonas sp. DMC3 | GFF3747 | | Bifunctional ligase/repressor BirA | cofit | 36 | 63 |
| | Rhodospirillum rubrum S1H | Rru_A1321 | | Biotin--acetyl-CoA-carboxylase ligase (NCBI) | cofit | 28 | 84 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS27265 | | bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor | insig. | 36 | 60 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS27265 | | bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor | strong | 36 | 60 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_05242 | | Bifunctional ligase/repressor BirA | cofit | 33 | 67 |
| | Fusobacterium nucleatum SB010 | HUW76_01165 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 36 | 56 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS20160 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 32 | 62 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS04765 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 35 | 66 |
| o | Azospirillum sp. SherDot2 | MPMX19_01732 | | Bifunctional ligase/repressor BirA | no data | 25 | 87 |
| | Methylophilus sp. DMC18 | GFF326 | | Bifunctional ligase/repressor BirA | no data | 26 | 93 |
| | Pseudomonas sp. RS175 | PFR28_04023 | | Bifunctional ligase/repressor BirA | insig. | 25 | 93 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4841 | | Biotin operon repressor / Biotin-protein ligase (EC 6.3.4.15) | sig. | 29 | 83 |
| o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS06335 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 27 | 83 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_14540 | | biotin--protein ligase | insig. | 35 | 56 |
| o | Bacteroides stercoris CC31F | HMPREF1181_RS09405 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 30 | 88 |
| | Pseudomonas stutzeri RCH2 | Psest_3628 | | birA, biotin-[acetyl-CoA-carboxylase] ligase region | no data | 33 | 65 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_12550 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 28 | 92 |
| | Erwinia tracheiphila SCR3 | LU632_RS19510 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 28 | 92 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1000 | | biotin/acetyl-CoA-carboxylase ligase (RefSeq) | strong | 27 | 93 |
| | Variovorax sp. OAS795 | ABID97_RS02300 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 26 | 70 |
| | Agrobacterium fabrum C58 | Atu1284 | | birA bifunctional protein | no data | 35 | 62 |
| | Alteromonas macleodii MIT1002 | MIT1002_03539 | | Bifunctional protein BirA | cofit | 33 | 59 |
| | Pantoea sp. MT58 | IAI47_18175 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 32 | 49 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2557 | birA | birA bifunctional protein (TIGR) | insig. | 24 | 84 |
| | Escherichia fergusonii Becca | EFB2_04637 | | Bifunctional ligase/repressor BirA | no data | 36 | 49 |
| | Escherichia coli ECOR38 | HEPCGN_12140 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 49 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS22935 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 49 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_01635 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 26 | 93 |
| | Escherichia coli BL21 | ECD_03854 | | bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase/ DNA-binding transcriptional repressor, bio-5'-AMP-binding | no data | 36 | 49 |
| | Escherichia coli ECOR27 | NOLOHH_05635 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 49 |
| | Escherichia coli ECRC100 | OKFHMN_13490 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 49 |
| | Escherichia coli ECRC101 | MCAODC_03990 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 49 |
| | Escherichia coli ECRC102 | NIAGMN_11240 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 49 |
| | Escherichia coli ECRC62 | BNILDI_05890 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 49 |
| | Escherichia coli ECRC98 | JDDGAC_17115 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 49 |
| | Escherichia coli ECRC99 | KEDOAH_14670 | birA | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 36 | 49 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_04077 | | Bifunctional ligase/repressor BirA | no data | 36 | 49 |
| | Erwinia amylovora T8 | OLJFJH_06610 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 26 | 83 |
| | Escherichia coli BW25113 | b3973 | birA | biotin--protein ligase (NCBI) | insig. | 35 | 49 |
| | Variovorax sp. SCN45 | GFF5385 | | Biotin--protein ligase (EC 6.3.4.9)(EC 6.3.4.10)(EC 6.3.4.11)(EC 6.3.4.15) | no data | 34 | 53 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2238 | | putative biotin--(acetyl-CoA carboxylase) synthetase (NCBI ptt file) | no data | 32 | 61 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3217 | | Biotin operon repressor / Biotin-protein ligase (EC 6.3.4.15) | no data | 29 | 78 |
| | Shewanella sp. ANA-3 | Shewana3_0183 | | biotin--protein ligase (RefSeq) | no data | 27 | 92 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS22855 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 32 | 49 |
| | Mycobacterium tuberculosis H37Rv | Rv3279c | | Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (biotin--protein ligase) | no data | 27 | 84 |
| | Dickeya dadantii 3937 | DDA3937_RS01030 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 33 | 49 |
| | Shewanella oneidensis MR-1 | SO0214 | birA | birA bifunctional protein (NCBI ptt file) | no data | 33 | 49 |
| | Rahnella sp. WP5 | EX31_RS17135 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 31 | 60 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_09915 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 28 | 92 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS05720 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 33 | 55 |
| | Pseudomonas segetis P6 | MPMX49_00915 | | Bifunctional ligase/repressor BirA | no data | 31 | 49 |
| | Dickeya dianthicola 67-19 | HGI48_RS01025 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 33 | 49 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1330 | | biotin--acetyl-CoA-carboxylase ligase (RefSeq) | no data | 26 | 65 |
| | Dickeya dianthicola ME23 | DZA65_RS01090 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 33 | 49 |
| | Shewanella amazonensis SB2B | Sama_0197 | | biotin--protein ligase (RefSeq) | no data | 27 | 83 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03107 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 34 | 61 |
| | Klebsiella michiganensis M5al | BWI76_RS01425 | | bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor | no data | 34 | 49 |
| | Enterobacter sp. TBS_079 | MPMX20_04425 | | Bifunctional ligase/repressor BirA | no data | 33 | 49 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_4037 | | birA, biotin-[acetyl-CoA-carboxylase] ligase region/BirA biotin operon repressor domain | no data | 34 | 51 |
| | Rhizobium sp. OAE497 | ABIE40_RS07255 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 32 | 67 |
| | Acinetobacter radioresistens SK82 | MPMX26_02465 | | Bifunctional ligase/repressor BirA | no data | 25 | 82 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_00655 | | Bifunctional ligase/repressor BirA | no data | 31 | 55 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS18380 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 31 | 52 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0695 | | birA, biotin-[acetyl-CoA-carboxylase] ligase region | no data | 25 | 88 |
| o | Xanthobacter sp. DMC5 | GFF1236 | | Bifunctional ligase/repressor BirA | no data | 24 | 93 |
| | Marinobacter adhaerens HP15 | HP15_363 | | biotin-protein ligase | insig. | 28 | 57 |
| | Serratia liquefaciens MT49 | IAI46_01185 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 31 | 49 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03185 | | biotin--[acetyl-CoA-carboxylase] ligase | cofit | 27 | 54 |
| | Caulobacter crescentus NA1000 | CCNA_02014 | | Biotin-(acetyl-CoA carboxylase) ligase | no data | 30 | 69 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02014 | | Biotin-(acetyl-CoA carboxylase) ligase | no data | 30 | 69 |
| o | Phocaeicola dorei CL03T12C01 | ABI39_RS09495 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 26 | 85 |
| | Pectobacterium carotovorum WPP14 | HER17_RS20500 | | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | no data | 24 | 79 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS07235 | | biotin | no data | 26 | 93 |
| o | Sinorhizobium meliloti 1021 | SMc01928 | | biotin--[acetyl-CoA-carboxylase] synthetase | no data | 26 | 90 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1855 | | birA, biotin-[acetyl-CoA-carboxylase] ligase region | no data | 29 | 60 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2429 | | birA, biotin-[acetyl-CoA-carboxylase] ligase region | no data | 32 | 58 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS20995 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 30 | 59 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS13940 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 33 | 49 |
| | Sphingobium sp. HT1-2 | GFF2105 | | Biotin--protein ligase (EC 6.3.4.9)(EC 6.3.4.10)(EC 6.3.4.11)(EC 6.3.4.15) | no data | 27 | 62 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2493 | | Biotin--protein ligase (EC 6.3.4.9, EC 6.3.4.10, EC 6.3.4.11, EC 6.3.4.15) | no data | 30 | 51 |
| | Bosea sp. OAE506 | ABIE41_RS17870 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 30 | 41 |
| | Shewanella loihica PV-4 | Shew_0142 | | biotin--protein ligase (RefSeq) | no data | 26 | 92 |
| | Rhodopseudomonas palustris CGA009 | TX73_015215 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 30 | 48 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_0345 | birA | Biotin--acetyl-CoA-carboxylase ligase | no data | 26 | 71 |
| | Acinetobacter baumannii LAC-4 | RR41_RS15290 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 28 | 56 |
| | Pseudomonas sp. S08-1 | OH686_15250 | | Biotin operon repressor / Biotin--protein ligase | no data | 35 | 50 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS17370 | | biotin--[acetyl-CoA-carboxylase] ligase | no data | 34 | 55 |