Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_06815 | | GGDEF domain-containing protein | insig. | 100 | 100 |
o | Alteromonas macleodii MIT1002 | MIT1002_01203 | | putative diguanylate cyclase YcdT | insig. | 38 | 96 |
o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.3367.1 | | GGDEF family protein | insig. | 33 | 98 |
o | Lysobacter sp. OAE881 | ABIE51_RS07485 | | ligand-binding sensor domain-containing diguanylate cyclase | insig. | 34 | 95 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1047.1 | | GGDEF family protein | insig. | 32 | 96 |
| Alteromonas macleodii MIT1002 | MIT1002_01743 | | putative diguanylate cyclase YdaM | insig. | 25 | 98 |
o | Rhodanobacter sp. FW510-T8 | OKGIIK_16885 | | GGDEF domain-containing protein | insig. | 25 | 92 |
o | Rhodanobacter denitrificans MT42 | LRK55_RS17540 | | ligand-binding sensor domain-containing diguanylate cyclase | insig. | 26 | 94 |
o | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS17315 | | ligand-binding sensor domain-containing diguanylate cyclase | insig. | 26 | 94 |
| Bacteroides ovatus ATCC 8483 | BACOVA_05479 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 23 | 78 |
| Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS14910 | | helix-turn-helix domain-containing protein | insig. | 23 | 80 |
| Bacteroides stercoris CC31F | HMPREF1181_RS06690 | | response regulator | sig. | 24 | 78 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3754 | | Signal transduction histidine kinase | insig. | 23 | 82 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS08780 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 24 | 78 |
| Bacteroides thetaiotaomicron VPI-5482 | BT4663 | | two-component system sensor histidine kinase/response (NCBI ptt file) | strong | 24 | 75 |
| Phocaeicola dorei CL03T12C01 | ABI39_RS10630 | | helix-turn-helix domain-containing protein | insig. | 22 | 80 |
o | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_19195 | | hypothetical protein | insig. | 24 | 85 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2760 | | Signal transduction histidine kinase | insig. | 23 | 79 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS06780 | | hybrid sensor histidine kinase/response regulator | insig. | 24 | 78 |
| Bacteroides ovatus ATCC 8483 | BACOVA_02667 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 22 | 80 |
| Phocaeicola dorei CL03T12C01 | ABI39_RS02675 | | response regulator | insig. | 22 | 79 |
| Bacteroides stercoris CC31F | HMPREF1181_RS08545 | | response regulator | insig. | 21 | 78 |
| Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS08450 | | response regulator | cofit | 22 | 79 |
| Bacteroides ovatus ATCC 8483 | BACOVA_01673 | | response regulator receiver domain protein | insig. | 24 | 75 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2824.1 | | GGDEF family protein | insig. | 24 | 98 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS13495 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 23 | 78 |
| Cellulophaga baltica 18 | M666_RS09795 | | two-component regulator propeller domain-containing protein | insig. | 22 | 81 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS02485 | | hypothetical protein | insig. | 22 | 78 |
| Shewanella amazonensis SB2B | Sama_0993 | | ligand-binding sensor domain-containing protein (RefSeq) | insig. | 22 | 78 |
| Bacteroides ovatus ATCC 8483 | BACOVA_04394 | | response regulator receiver domain protein | strong | 23 | 78 |
| Shewanella loihica PV-4 | Shew_2791 | | PAS/PAC sensor signal transduction histidine kinase (RefSeq) | insig. | 23 | 78 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS11205 | | hybrid sensor histidine kinase/response regulator | insig. | 23 | 80 |
| Lysobacter sp. OAE881 | ABIE51_RS02660 | | sensor histidine kinase | insig. | 23 | 94 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS06050 | | hypothetical protein | insig. | 22 | 78 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS14215 | | hypothetical protein | insig. | 22 | 79 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1645 | | Signal transduction histidine kinase | insig. | 22 | 83 |
| Bacteroides ovatus ATCC 8483 | BACOVA_02648 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | cofit | 23 | 78 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4259 | | His Kinase A (phosphoacceptor) domain./Response regulator receiver domain./Y_Y_Y domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase./Two component regulator propeller./Bacterial regulatory helix-turn-helix proteins, AraC family. | insig. | 23 | 78 |
| Cellulophaga baltica 18 | M666_RS00005 | | two-component regulator propeller domain-containing protein | insig. | 23 | 79 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2825.1 | | hypothetical protein | insig. | 24 | 71 |
| Bacteroides ovatus ATCC 8483 | BACOVA_02800 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 23 | 75 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS15155 | | hybrid sensor histidine kinase/response regulator transcription factor | cofit | 22 | 80 |
| Bacteroides thetaiotaomicron VPI-5482 | BT3678 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 22 | 78 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS11130 | | two-component regulator propeller domain-containing protein | cofit | 23 | 81 |
| Lysobacter sp. OAE881 | ABIE51_RS10615 | | sensor histidine kinase | insig. | 22 | 75 |
| Bacteroides ovatus ATCC 8483 | BACOVA_02857 | | conserved hypothetical protein TIGR03982 | insig. | 23 | 77 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS05785 | | hypothetical protein | insig. | 22 | 66 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS10265 | | hypothetical protein | insig. | 22 | 78 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS00710 | | hypothetical protein | insig. | 22 | 78 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS03150 | | two-component regulator propeller domain-containing protein | insig. | 22 | 75 |
| Bacteroides thetaiotaomicron VPI-5482 | BT3465 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 21 | 95 |
| Shewanella sp. ANA-3 | Shewana3_0269 | | diguanylate cyclase (RefSeq) | cofit | 42 | 17 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_3916 | | Histidine kinase/Y_Y_Y domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | insig. | 23 | 78 |
| Shewanella sp. ANA-3 | Shewana3_3829 | | diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | cofit | 21 | 79 |
| Shewanella oneidensis MR-1 | SO4457 | | GGDEF domain protein (NCBI ptt file) | insig. | 40 | 17 |
| Rhizobium sp. OAE497 | ABIE40_RS14600 | | GGDEF domain-containing protein | insig. | 39 | 20 |
| Bacteroides ovatus ATCC 8483 | BACOVA_01894 | | transcriptional regulator, AraC family | strong | 23 | 80 |
| Bacteroides thetaiotaomicron VPI-5482 | BT3049 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | cofit | 22 | 76 |
| Bacteroides stercoris CC31F | HMPREF1181_RS08885 | | response regulator | strong | 22 | 78 |
| Bacteroides ovatus ATCC 8483 | BACOVA_01324 | | hypothetical protein | insig. | 22 | 76 |
| Shewanella oneidensis MR-1 | SO0341 | | sensory box protein (NCBI ptt file) | insig. | 22 | 74 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2398.1 | | hypothetical protein | insig. | 24 | 77 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_24210 | | diguanylate cyclase | sig. | 39 | 19 |
| Pseudomonas sp. RS175 | PFR28_02096 | | hypothetical protein | insig. | 37 | 19 |
| Pseudomonas sp. DMC3 | GFF2253 | | hypothetical protein | insig. | 38 | 17 |
| Pseudomonas sp. SVBP6 | COO64_RS16430 | | sensor domain-containing diguanylate cyclase | insig. | 34 | 18 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1608.1 | | Histidine kinase/response regulator hybrid protein | insig. | 22 | 81 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1642 | | diguanylate cyclase (GGDEF domain) with PAS/PAC sensor | insig. | 37 | 19 |
| Methylophilus sp. DMC18 | GFF1918 | | hypothetical protein | cofit | 37 | 17 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_4533 | | hypothetical protein | insig. | 36 | 18 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4346 | | Signal transduction histidine kinase | insig. | 24 | 79 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS08375 | | two-component regulator propeller domain-containing protein | insig. | 23 | 82 |
| Shewanella amazonensis SB2B | Sama_2623 | | cyclic nucleotide phosphodiesterase, putative (RefSeq) | strong | 37 | 22 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_0509 | | diguanylate cyclase (GGDEF) domain | strong | 23 | 77 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS12625 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 22 | 81 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2200.1 | | Transcriptional regulator | insig. | 44 | 16 |
| Bacteroides thetaiotaomicron VPI-5482 | BT0366 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | sig. | 23 | 81 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS12345 | | hypothetical protein | insig. | 23 | 76 |
| Agrobacterium fabrum C58 | Atu1691 | | GGDEF family protein | insig. | 37 | 19 |
| Bacteroides stercoris CC31F | HMPREF1181_RS08430 | | response regulator | insig. | 21 | 75 |
| Azospirillum sp. SherDot2 | MPMX19_03993 | | hypothetical protein | insig. | 39 | 19 |
| Pseudomonas sp. BP01 | JOY50_RS14585 | | sensor domain-containing diguanylate cyclase | insig. | 37 | 18 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS12365 | | ATP-binding protein | insig. | 24 | 77 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS19095 | | hybrid sensor histidine kinase/response regulator | insig. | 24 | 76 |
| Marinobacter adhaerens HP15 | HP15_p187g173 | | protein containing diguanylate cyclase, predicted domains | insig. | 36 | 23 |
| Rhodanobacter denitrificans MT42 | LRK55_RS12100 | | hybrid sensor histidine kinase/response regulator | strong | 24 | 77 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS21280 | | hypothetical protein | insig. | 22 | 82 |
| Alteromonas macleodii MIT1002 | MIT1002_04038 | | putative diguanylate cyclase AdrA | insig. | 39 | 18 |
| Paraburkholderia graminis OAS925 | ABIE53_004649 | | diguanylate cyclase (GGDEF)-like protein | strong | 35 | 18 |
| Bacteroides thetaiotaomicron VPI-5482 | BT3097 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 22 | 82 |
| Rhodospirillum rubrum S1H | Rru_A3391 | | Putative diguanylate cyclase (GGDEF domain) (NCBI) | insig. | 42 | 17 |
| Shewanella loihica PV-4 | Shew_0452 | | diguanylate cyclase (RefSeq) | insig. | 38 | 19 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01379 | | diguanylate cyclase/phosphodiesterase | insig. | 42 | 17 |
| Bacteroides ovatus ATCC 8483 | BACOVA_00239 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 22 | 77 |
| Shewanella amazonensis SB2B | Sama_3581 | | GGDEF domain-containing protein (RefSeq) | insig. | 41 | 16 |
| Rhodopseudomonas palustris CGA009 | TX73_008830 | | diguanylate cyclase | insig. | 38 | 17 |
| Acidovorax sp. GW101-3H11 | Ac3H11_3285 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | sig. | 38 | 20 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02129 | | diguanylate cyclase (GGDEF) domain-containing protein | insig. | 35 | 22 |
| Pseudomonas putida KT2440 | PP_1411 | | GGDEF domain protein | insig. | 36 | 18 |
| Burkholderia phytofirmans PsJN | BPHYT_RS28910 | | diguanylate phosphodiesterase | insig. | 42 | 17 |