| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06815 | | GGDEF domain-containing protein | insig. | 100 | 100 |
| o | Alteromonas macleodii MIT1002 | MIT1002_01203 | | putative diguanylate cyclase YcdT | insig. | 38 | 96 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.3367.1 | | GGDEF family protein | insig. | 33 | 98 |
| | Lysobacter sp. OAE881 | ABIE51_RS07485 | | ligand-binding sensor domain-containing diguanylate cyclase | insig. | 34 | 95 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1047.1 | | GGDEF family protein | insig. | 32 | 96 |
| | Alteromonas macleodii MIT1002 | MIT1002_01743 | | putative diguanylate cyclase YdaM | insig. | 25 | 98 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_16885 | | GGDEF domain-containing protein | insig. | 25 | 92 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS17540 | | ligand-binding sensor domain-containing diguanylate cyclase | cofit | 26 | 94 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS17315 | | ligand-binding sensor domain-containing diguanylate cyclase | insig. | 26 | 94 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_05479 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 23 | 78 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS14910 | | helix-turn-helix domain-containing protein | insig. | 23 | 80 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS06690 | | response regulator | sig. | 24 | 78 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3754 | | Signal transduction histidine kinase | insig. | 23 | 82 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS08780 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 24 | 78 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4663 | | two-component system sensor histidine kinase/response (NCBI ptt file) | strong | 24 | 75 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS10630 | | helix-turn-helix domain-containing protein | insig. | 22 | 80 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_19195 | | hypothetical protein | insig. | 24 | 85 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2760 | | Signal transduction histidine kinase | insig. | 23 | 79 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS06780 | | hybrid sensor histidine kinase/response regulator | insig. | 24 | 78 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02667 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 22 | 80 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS02675 | | response regulator | insig. | 22 | 79 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS08545 | | response regulator | insig. | 21 | 78 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS08450 | | response regulator | strong | 22 | 79 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2824.1 | | GGDEF family protein | insig. | 24 | 98 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01673 | | response regulator receiver domain protein | insig. | 24 | 75 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS13495 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 23 | 78 |
| | Cellulophaga baltica 18 | M666_RS09795 | | two-component regulator propeller domain-containing protein | insig. | 22 | 81 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS02485 | | hypothetical protein | insig. | 22 | 78 |
| | Shewanella amazonensis SB2B | Sama_0993 | | ligand-binding sensor domain-containing protein (RefSeq) | insig. | 22 | 78 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04394 | | response regulator receiver domain protein | strong | 23 | 78 |
| | Shewanella loihica PV-4 | Shew_2791 | | PAS/PAC sensor signal transduction histidine kinase (RefSeq) | insig. | 23 | 78 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS11205 | | hybrid sensor histidine kinase/response regulator | insig. | 23 | 80 |
| | Lysobacter sp. OAE881 | ABIE51_RS02660 | | sensor histidine kinase | insig. | 23 | 94 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS06050 | | hypothetical protein | insig. | 22 | 78 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS14215 | | hypothetical protein | insig. | 22 | 79 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1645 | | Signal transduction histidine kinase | insig. | 22 | 83 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02648 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | cofit | 23 | 78 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4259 | | His Kinase A (phosphoacceptor) domain./Response regulator receiver domain./Y_Y_Y domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase./Two component regulator propeller./Bacterial regulatory helix-turn-helix proteins, AraC family. | insig. | 23 | 78 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2825.1 | | hypothetical protein | insig. | 24 | 71 |
| | Cellulophaga baltica 18 | M666_RS00005 | | two-component regulator propeller domain-containing protein | insig. | 23 | 79 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02800 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 23 | 75 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS15155 | | hybrid sensor histidine kinase/response regulator transcription factor | cofit | 22 | 80 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3678 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 22 | 78 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS11130 | | two-component regulator propeller domain-containing protein | cofit | 23 | 81 |
| | Lysobacter sp. OAE881 | ABIE51_RS10615 | | sensor histidine kinase | insig. | 22 | 75 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02857 | | conserved hypothetical protein TIGR03982 | insig. | 23 | 77 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS05785 | | hypothetical protein | insig. | 22 | 66 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS10265 | | hypothetical protein | insig. | 22 | 78 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS00710 | | hypothetical protein | insig. | 22 | 78 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS03150 | | two-component regulator propeller domain-containing protein | insig. | 22 | 75 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3465 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 21 | 95 |
| | Shewanella sp. ANA-3 | Shewana3_0269 | | diguanylate cyclase (RefSeq) | cofit | 42 | 17 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3916 | | Histidine kinase/Y_Y_Y domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | insig. | 23 | 78 |
| | Shewanella sp. ANA-3 | Shewana3_3829 | | diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | cofit | 21 | 79 |
| | Shewanella oneidensis MR-1 | SO4457 | | GGDEF domain protein (NCBI ptt file) | insig. | 40 | 17 |
| | Rhizobium sp. OAE497 | ABIE40_RS14600 | | GGDEF domain-containing protein | insig. | 39 | 20 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01894 | | transcriptional regulator, AraC family | strong | 23 | 80 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3049 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | cofit | 22 | 76 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS08885 | | response regulator | strong | 22 | 78 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01324 | | hypothetical protein | insig. | 22 | 76 |
| | Shewanella oneidensis MR-1 | SO0341 | | sensory box protein (NCBI ptt file) | insig. | 22 | 74 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2398.1 | | hypothetical protein | insig. | 24 | 77 |
| | Pseudomonas sp. RS175 | PFR28_02096 | | hypothetical protein | insig. | 37 | 19 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_24210 | | diguanylate cyclase | sig. | 39 | 19 |
| | Pseudomonas sp. DMC3 | GFF2253 | | hypothetical protein | insig. | 38 | 17 |
| | Pseudomonas sp. SVBP6 | COO64_RS16430 | | sensor domain-containing diguanylate cyclase | insig. | 34 | 18 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1642 | | diguanylate cyclase (GGDEF domain) with PAS/PAC sensor | insig. | 37 | 19 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4533 | | hypothetical protein | insig. | 36 | 18 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4346 | | Signal transduction histidine kinase | insig. | 24 | 79 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS08375 | | two-component regulator propeller domain-containing protein | insig. | 23 | 82 |
| | Methylophilus sp. DMC18 | GFF1918 | | hypothetical protein | cofit | 37 | 17 |
| | Shewanella amazonensis SB2B | Sama_2623 | | cyclic nucleotide phosphodiesterase, putative (RefSeq) | strong | 37 | 22 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0509 | | diguanylate cyclase (GGDEF) domain | strong | 23 | 77 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2200.1 | | Transcriptional regulator | insig. | 44 | 16 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS12625 | | hybrid sensor histidine kinase/response regulator transcription factor | strong | 22 | 81 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0366 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | sig. | 23 | 81 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS12345 | | hypothetical protein | insig. | 23 | 76 |
| | Agrobacterium fabrum C58 | Atu1691 | | GGDEF family protein | insig. | 37 | 19 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS08430 | | response regulator | insig. | 21 | 75 |
| | Azospirillum sp. SherDot2 | MPMX19_03993 | | hypothetical protein | insig. | 39 | 19 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS12365 | | ATP-binding protein | insig. | 24 | 77 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS19095 | | hybrid sensor histidine kinase/response regulator | insig. | 24 | 76 |
| | Pseudomonas sp. BP01 | JOY50_RS14585 | | sensor domain-containing diguanylate cyclase | insig. | 37 | 18 |
| | Marinobacter adhaerens HP15 | HP15_p187g173 | | protein containing diguanylate cyclase, predicted domains | insig. | 36 | 23 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS12100 | | hybrid sensor histidine kinase/response regulator | strong | 24 | 77 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS21280 | | hypothetical protein | insig. | 22 | 82 |
| | Alteromonas macleodii MIT1002 | MIT1002_04038 | | putative diguanylate cyclase AdrA | insig. | 39 | 18 |
| | Paraburkholderia graminis OAS925 | ABIE53_004649 | | diguanylate cyclase (GGDEF)-like protein | strong | 35 | 18 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3097 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 22 | 82 |
| | Rhodospirillum rubrum S1H | Rru_A3391 | | Putative diguanylate cyclase (GGDEF domain) (NCBI) | insig. | 42 | 17 |
| | Shewanella loihica PV-4 | Shew_0452 | | diguanylate cyclase (RefSeq) | insig. | 38 | 19 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01379 | | diguanylate cyclase/phosphodiesterase | insig. | 42 | 17 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3285 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | sig. | 38 | 20 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_00239 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 22 | 77 |
| | Shewanella amazonensis SB2B | Sama_3581 | | GGDEF domain-containing protein (RefSeq) | insig. | 41 | 16 |
| | Rhodopseudomonas palustris CGA009 | TX73_008830 | | diguanylate cyclase | insig. | 38 | 17 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02129 | | diguanylate cyclase (GGDEF) domain-containing protein | insig. | 35 | 22 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS01055 | | GGDEF domain-containing protein | sig. | 38 | 16 |
| | Pseudomonas putida KT2440 | PP_1411 | | GGDEF domain protein | insig. | 36 | 18 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS28910 | | diguanylate phosphodiesterase | insig. | 42 | 17 |
| | Pectobacterium carotovorum WPP14 | HER17_RS13535 | | sensor domain-containing diguanylate cyclase | insig. | 39 | 17 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_16145 | | GGDEF domain-containing protein | sig. | 38 | 16 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS34485 | | GGDEF domain-containing protein | insig. | 38 | 16 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS34775 | | diguanylate cyclase | insig. | 35 | 18 |
| | Agrobacterium fabrum C58 | Atu3061 | | diguanylate cyclase | insig. | 32 | 24 |
| | Shewanella oneidensis MR-1 | SO3489 | | GGDEF domain protein (NCBI ptt file) | insig. | 38 | 18 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_5815 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 38 | 22 |
| | Sphingobium sp. HT1-2 | GFF958 | | Diguanylate cyclase | insig. | 37 | 21 |
| | Agrobacterium fabrum C58 | Atu1060 | | two component response regulator | insig. | 35 | 17 |
| | Pseudomonas stutzeri RCH2 | Psest_2106 | | diguanylate cyclase (GGDEF) domain | sig. | 35 | 19 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0138 | | transcriptional regulator (NCBI ptt file) | insig. | 22 | 77 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2528 | | GGDEF domain protein | insig. | 39 | 16 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS01260 | | GGDEF domain-containing protein | insig. | 38 | 19 |
| | Azospirillum sp. SherDot2 | MPMX19_06692 | | hypothetical protein | insig. | 38 | 18 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1477 | | diguanylate cyclase with PAS/PAC sensor (RefSeq) | sig. | 35 | 18 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_03505 | | hypothetical protein | insig. | 39 | 16 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1290 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain | insig. | 37 | 17 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1778 | | diguanylate cyclase (GGDEF) domain | sig. | 37 | 20 |
| | Xanthobacter sp. DMC5 | GFF2622 | | hypothetical protein | insig. | 37 | 18 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS03955 | | response regulator | insig. | 20 | 77 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS09500 | | response regulator | insig. | 20 | 77 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02648 | | diguanylate cyclase (GGDEF) domain-containing protein | insig. | 38 | 18 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0300 | | diguanylate cyclase (GGDEF) domain | insig. | 38 | 18 |
| | Pseudomonas sp. RS175 | PFR28_04630 | | hypothetical protein | insig. | 37 | 18 |
| | Dechlorosoma suillum PS | Dsui_2893 | | diguanylate cyclase (GGDEF) domain-containing protein | cofit | 35 | 23 |
| | Caulobacter crescentus NA1000 | CCNA_01926 | | GGDEF diguanylate cyclase DgcB | strong | 36 | 19 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01926 | | GGDEF diguanylate cyclase DgcB | cofit | 36 | 19 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS03465 | | response regulator | sig. | 22 | 84 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2860 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | insig. | 21 | 78 |
| | Marinobacter adhaerens HP15 | HP15_3345 | | GGDEF domain protein | insig. | 39 | 17 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS16450 | | diguanylate cyclase | insig. | 35 | 18 |
| | Rhizobium sp. OAE497 | ABIE40_RS11215 | | diguanylate cyclase | insig. | 35 | 21 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS23570 | | diguanylate cyclase | insig. | 39 | 19 |
| | Dechlorosoma suillum PS | Dsui_1430 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein | cofit | 37 | 18 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS03890 | | GGDEF domain-containing protein | insig. | 36 | 21 |
| | Agrobacterium fabrum C58 | Atu2091 | | GGDEF family protein | insig. | 37 | 18 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1014 | | diguanylate cyclase (RefSeq) | insig. | 35 | 18 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_11340 | | GGDEF domain-containing protein | insig. | 38 | 18 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4322 | | Bll3041 protein | insig. | 36 | 21 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03607 | | PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein | insig. | 34 | 18 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1157 | | diguanylate cyclase with PAS/PAC sensor | insig. | 38 | 17 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1157 | | diguanylate cyclase with PAS/PAC sensor | insig. | 38 | 17 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1029 | | Putative membrane protein | insig. | 38 | 18 |
| | Rhodopseudomonas palustris CGA009 | TX73_009350 | | GGDEF domain-containing protein | insig. | 36 | 17 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01301 | | hypothetical protein | insig. | 23 | 72 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS13580 | | response regulator | strong | 22 | 54 |
| | Shewanella amazonensis SB2B | Sama_1759 | | GGDEF domain-containing protein (RefSeq) | insig. | 42 | 17 |
| | Enterobacter sp. TBS_079 | MPMX20_02446 | | Diguanylate cyclase DgcM | insig. | 38 | 18 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_18905 | | GGDEF domain-containing protein | cofit | 38 | 18 |
| | Shewanella sp. ANA-3 | Shewana3_0449 | | diguanylate cyclase with GAF sensor (RefSeq) | insig. | 37 | 17 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_28530 | | diguanylate cyclase | insig. | 35 | 22 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS07185 | | two-component regulator propeller domain-containing protein | insig. | 23 | 79 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2923 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 21 | 79 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS13615 | | bifunctional diguanylate cyclase/phosphodiesterase | insig. | 40 | 17 |
| | Pseudomonas simiae WCS417 | PS417_21835 | | histidine kinase | insig. | 38 | 18 |
| | Shewanella amazonensis SB2B | Sama_3137 | | response regulator receiver protein (RefSeq) | strong | 33 | 19 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_05614 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 22 | 65 |
| | Azospirillum brasilense Sp245 | AZOBR_RS15555 | | transcriptional regulator | insig. | 41 | 17 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_359 | | GGDEF domain protein | insig. | 39 | 16 |
| | Pseudomonas segetis P6 | ACVTMO_RS02560 | siaD | biofilm regulation diguanylate cyclase SiaD | strong | 38 | 16 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_2281 | | GGDEF domain protein | insig. | 38 | 17 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_2281 | | GGDEF domain protein | insig. | 38 | 17 |
| | Dechlorosoma suillum PS | Dsui_1361 | | diguanylate cyclase (GGDEF) domain-containing protein | insig. | 37 | 19 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS12495 | | GGDEF domain-containing protein | cofit | 37 | 17 |
| | Enterobacter sp. TBS_079 | MPMX20_00664 | | hypothetical protein | insig. | 37 | 20 |
| | Xanthobacter sp. DMC5 | GFF1488 | | hypothetical protein | insig. | 36 | 18 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0723 | | diguanylate cyclase (GGDEF) domain | insig. | 35 | 18 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_1001 | | PAS domain S-box/diguanylate cyclase (GGDEF) domain | insig. | 38 | 18 |
| | Pseudomonas sp. S08-1 | OH686_03265 | | diguanylate cyclase (GGDEF domain) with PAS/PAC sensor | insig. | 34 | 19 |
| | Pseudomonas stutzeri RCH2 | Psest_1455 | | diguanylate cyclase (GGDEF) domain | insig. | 31 | 23 |
| | Shewanella sp. ANA-3 | Shewana3_0308 | | diguanylate cyclase (RefSeq) | insig. | 32 | 22 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3582 | | diguanylate cyclase (GGDEF domain) | insig. | 38 | 18 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.3651.1 | | Sensor histidine kinase | insig. | 37 | 21 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3356 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 37 | 16 |
| | Azospirillum sp. SherDot2 | MPMX19_05017 | | hypothetical protein | insig. | 36 | 19 |
| | Pseudomonas sp. S08-1 | OH686_05940 | | GGDEF domain protein | cofit | 33 | 25 |
| | Xanthobacter sp. DMC5 | GFF713 | | hypothetical protein | insig. | 31 | 19 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_3203 | | diguanylate cyclase (RefSeq) | cofit | 29 | 22 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_00976 | | response regulator receiver domain protein | insig. | 21 | 75 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.3472.1 | | sensor histidine kinase | insig. | 38 | 18 |
| | Marinobacter adhaerens HP15 | HP15_2378 | | sensory box/GGDEF family protein | insig. | 37 | 19 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS04610 | | GGDEF domain-containing protein | insig. | 34 | 21 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS01485 | | hypothetical protein | insig. | 22 | 76 |
| | Cellulophaga baltica 18 | M666_RS02185 | | two-component regulator propeller domain-containing protein | insig. | 21 | 72 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_936 | | GGDEF domain protein | cofit | 36 | 22 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS07410 | | diguanylate cyclase | cofit | 35 | 19 |
| | Bosea sp. OAE506 | ABIE41_RS13785 | | EAL domain-containing protein | insig. | 33 | 18 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3328 | | GGDEF domain protein | insig. | 33 | 23 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3328 | | GGDEF domain protein | insig. | 33 | 23 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS03345 | | hypothetical protein | insig. | 23 | 77 |
| | Pseudomonas sp. DMC3 | GFF625 | | hypothetical protein | cofit | 38 | 16 |
| | Klebsiella michiganensis M5al | BWI76_RS03520 | | diguanylate cyclase | cofit | 38 | 16 |
| | Pseudomonas segetis P6 | ACVTMO_RS01545 | | diguanylate cyclase | insig. | 35 | 19 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_18375 | | GGDEF domain-containing protein | insig. | 35 | 17 |
| | Paraburkholderia graminis OAS925 | ABIE53_004409 | | diguanylate cyclase (GGDEF)-like protein | sig. | 35 | 22 |
| | Escherichia coli ECOR27 | NOLOHH_01540 | adrA | diguanylate cyclase AdrA | insig. | 34 | 18 |
| | Escherichia coli ECRC100 | OKFHMN_08615 | adrA | diguanylate cyclase AdrA | insig. | 34 | 18 |
| | Escherichia coli ECRC101 | MCAODC_27840 | adrA | diguanylate cyclase AdrA | insig. | 34 | 18 |
| | Escherichia coli ECRC102 | NIAGMN_06670 | adrA | diguanylate cyclase AdrA | insig. | 34 | 18 |
| | Escherichia coli ECRC98 | JDDGAC_12270 | adrA | diguanylate cyclase AdrA | insig. | 34 | 18 |
| | Escherichia coli ECRC99 | KEDOAH_19350 | adrA | diguanylate cyclase AdrA | no data | 34 | 18 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03289 | | putative diguanylate cyclase DgcC | insig. | 34 | 18 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3573 | | diguanylate cyclase (GGDEF) domain | insig. | 37 | 18 |
| | Acinetobacter radioresistens SK82 | MPMX26_02261 | | hypothetical protein | no data | 29 | 22 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4150 | | diguanylate cyclase | strong | 39 | 17 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS29770 | | diguanylate cyclase | insig. | 37 | 18 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_20465 | | diguanylate cyclase | cofit | 37 | 17 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0300 | | diguanylate cyclase (GGDEF) domain | insig. | 36 | 17 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_588 | | GGDEF domain protein | insig. | 36 | 19 |
| | Pseudomonas sp. S08-1 | OH686_13445 | | hypothetical protein | insig. | 35 | 19 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_3834 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 35 | 22 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2586 | | diguanylate cyclase (GGDEF) domain | insig. | 34 | 17 |
| | Variovorax sp. OAS795 | ABID97_RS28160 | | sensor domain-containing diguanylate cyclase | insig. | 33 | 22 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS09380 | | GGDEF domain-containing protein | insig. | 33 | 20 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS09010 | | response regulator | insig. | 23 | 58 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0187 | | diguanylate cyclase (GGDEF) domain | insig. | 38 | 17 |
| | Shewanella sp. ANA-3 | Shewana3_4330 | | diguanylate cyclase with GAF sensor (RefSeq) | insig. | 37 | 17 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_11435 | | hypothetical protein | insig. | 37 | 18 |
| | Azospirillum brasilense Sp245 | AZOBR_RS09565 | | diguanylate cyclase | insig. | 34 | 18 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4282 | | Protein YaiC | insig. | 34 | 18 |
| | Paraburkholderia graminis OAS925 | ABIE53_000542 | | diguanylate cyclase (GGDEF)-like protein | insig. | 33 | 22 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS07895 | | GGDEF domain-containing protein | sig. | 32 | 21 |
| | Ralstonia solanacearum UW163 | UW163_RS05730 | | GGDEF domain-containing protein | insig. | 32 | 21 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS06705 | | sensor domain-containing diguanylate cyclase | cofit | 40 | 17 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1660 | | GGDEF domain protein | insig. | 38 | 17 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS17460 | | PAS domain S-box protein | cofit | 37 | 17 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS14465 | wspR;inference=COORDINATES | Wsp signal transduction system regulator diguanylate cyclase WspR | sig. | 36 | 16 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS42660 | wspR;inference=COORDINATES | Wsp signal transduction system regulator diguanylate cyclase WspR | sig. | 36 | 16 |
| | Pseudomonas sp. S08-1 | OH686_12185 | | GGDEF domain protein | cofit | 36 | 20 |
| | Agrobacterium fabrum C58 | Atu1257 | | GGDEF family protein | insig. | 35 | 17 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3763 | | GGDEF domain protein | insig. | 35 | 19 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3763 | | GGDEF domain protein | insig. | 35 | 19 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_3653 | | GGDEF domain protein | insig. | 34 | 16 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3653 | | GGDEF domain protein | insig. | 34 | 16 |
| | Paraburkholderia graminis OAS925 | ABIE53_006414 | | diguanylate cyclase (GGDEF)-like protein | insig. | 38 | 18 |
| | Sinorhizobium meliloti 1021 | SMc01370 | | response regulator PleD | insig. | 36 | 18 |
| | Shewanella loihica PV-4 | Shew_3023 | | diguanylate cyclase (RefSeq) | insig. | 34 | 17 |
| | Marinobacter adhaerens HP15 | HP15_3763 | | response regulator receiver domain protein (CheY) | insig. | 34 | 20 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_00290 | | hypothetical protein | insig. | 39 | 16 |
| | Pseudomonas orientalis W4I3 | QF045_RS07670 | | sensor domain-containing diguanylate cyclase | insig. | 35 | 19 |
| | Methylophilus sp. DMC18 | GFF996 | | hypothetical protein | cofit | 33 | 21 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1537 | | diguanylate cyclase (RefSeq) | insig. | 36 | 19 |
| | Rhodopseudomonas palustris CGA009 | TX73_021305 | | diguanylate cyclase | insig. | 35 | 18 |
| | Shewanella amazonensis SB2B | Sama_2970 | | diguanylate cyclase (RefSeq) | insig. | 34 | 18 |
| | Cellulophaga baltica 18 | M666_RS18150 | | sensor histidine kinase | insig. | 23 | 37 |
| | Pseudomonas stutzeri RCH2 | Psest_0767 | | diguanylate cyclase (GGDEF) domain | sig. | 36 | 17 |
| | Escherichia coli ECRC62 | BNILDI_22955 | adrA | diguanylate cyclase AdrA | insig. | 33 | 18 |
| | Methylophilus sp. DMC18 | GFF267 | | Diguanylate cyclase VdcA | insig. | 38 | 16 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS20950 | | GGDEF domain-containing protein | insig. | 35 | 19 |
| | Dickeya dianthicola ME23 | DZA65_RS22520 | | diguanylate cyclase | insig. | 33 | 18 |