| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Agrobacterium fabrum C58 | Atu4202 | | methyltransferase | insig. | 100 | 100 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS18325 | | class I SAM-dependent methyltransferase | cofit | 45 | 94 |
| | Acinetobacter radioresistens SK82 | MPMX26_01104 | | Carboxy-S-adenosyl-L-methionine synthase | no data | 21 | 86 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS20255 | | trans-aconitate 2-methyltransferase | insig. | 35 | 48 |
| | Acinetobacter baumannii LAC-4 | RR41_RS11145 | | class I SAM-dependent methyltransferase | insig. | 28 | 85 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_05655 | | malonyl-[acyl-carrier protein] O-methyltransferase BioC | insig. | 40 | 42 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS08625 | | class I SAM-dependent methyltransferase | insig. | 25 | 92 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4751 | | Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39) | insig. | 31 | 67 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1 | | Trans-aconitate 2-methyltransferase (EC 2.1.1.144) | insig. | 29 | 68 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS20665 | | class I SAM-dependent methyltransferase | cofit | 26 | 92 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS22015 | | methyltransferase domain-containing protein | insig. | 39 | 48 |
| | Variovorax sp. SCN45 | GFF2415 | | Trans-aconitate 2-methyltransferase (EC 2.1.1.144) | insig. | 31 | 46 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS13495 | | SAM-dependent methyltransferase | insig. | 27 | 75 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_12620 | | Trans-aconitate 2-methyltransferase | insig. | 33 | 47 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS04800 | | trans-aconitate 2-methyltransferase | sig. | 35 | 41 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS04665 | | trans-aconitate 2-methyltransferase | insig. | 35 | 40 |
| | Sinorhizobium meliloti 1021 | SMc01426 | | hypothetical protein | insig. | 35 | 62 |
| | Pseudomonas sp. BP01 | JOY50_RS10255 | tam | trans-aconitate 2-methyltransferase | insig. | 34 | 40 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS27005 | | trans-aconitate 2-methyltransferase | insig. | 31 | 46 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS27005 | | trans-aconitate 2-methyltransferase | insig. | 31 | 46 |
| | Dickeya dianthicola 67-19 | HGI48_RS02395 | | trans-aconitate 2-methyltransferase | insig. | 30 | 48 |
| | Xanthobacter sp. DMC5 | GFF2934 | | Trans-aconitate 2-methyltransferase | insig. | 34 | 42 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0606 | | transcriptional regulator, ArsR family/methyltransferase, UbiE/COQ5 family (TIGR) | strong | 31 | 68 |
| | Pseudomonas simiae WCS417 | PS417_25365 | | trans-aconitate methyltransferase | insig. | 31 | 46 |
| | Pseudomonas sp. DMC3 | GFF2247 | | Trans-aconitate 2-methyltransferase | insig. | 31 | 47 |
| | Pseudomonas putida KT2440 | PP_2545 | | trans-aconitate methyltransferase | strong | 34 | 40 |
| | Pseudomonas segetis P6 | ACVTMO_RS10480 | tam | trans-aconitate 2-methyltransferase | insig. | 33 | 48 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS09935 | | trans-aconitate 2-methyltransferase | no data | 32 | 40 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3283 | | Trans-aconitate 2-methyltransferase (EC 2.1.1.144) | insig. | 32 | 40 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_17470 | | trans-aconitate methyltransferase | insig. | 30 | 47 |
| | Klebsiella michiganensis M5al | BWI76_RS19545 | | type 11 methyltransferase | no data | 36 | 43 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_21090 | | trans-aconitate methyltransferase | insig. | 30 | 52 |
| | Azospirillum brasilense Sp245 | AZOBR_RS03915 | | trans-aconitate 2-methyltransferase | insig. | 35 | 42 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS35700 | | trans-aconitate 2-methyltransferase | insig. | 32 | 47 |
| | Dickeya dadantii 3937 | DDA3937_RS02435 | | trans-aconitate 2-methyltransferase | insig. | 31 | 48 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0853 | | putative methyltransferase (NCBI ptt file) | sig. | 34 | 42 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.498.1 | | Biotin synthesis protein BioC | no data | 34 | 48 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS02045 | | class I SAM-dependent methyltransferase | insig. | 33 | 43 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS15405 | | methyltransferase domain-containing protein | sig. | 31 | 43 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS12045 | | trans-aconitate 2-methyltransferase | insig. | 32 | 52 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS06785 | | methyltransferase domain-containing protein | no data | 35 | 52 |
| | Variovorax sp. SCN45 | GFF3902 | | Trans-aconitate 2-methyltransferase (EC 2.1.1.144) | insig. | 35 | 43 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_00395 | | SAM-dependent methyltransferase | insig. | 32 | 40 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4540 | | Trans-aconitate 2-methyltransferase (EC 2.1.1.144) | insig. | 30 | 40 |
| | Acinetobacter radioresistens SK82 | MPMX26_00413 | | Trans-aconitate 2-methyltransferase | insig. | 32 | 55 |
| | Shewanella loihica PV-4 | Shew_2081 | | putative methyltransferase (RefSeq) | no data | 22 | 82 |
| | Pseudomonas sp. S08-1 | OH686_16710 | | Glycosyltransferase | insig. | 36 | 33 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_08380 | | DNA-binding protein | cofit | 29 | 61 |
| | Erwinia tracheiphila SCR3 | LU632_RS22230 | | helix-turn-helix domain-containing protein | cofit | 29 | 61 |
| | Pseudomonas sp. RS175 | PFR28_02884 | | Trans-aconitate 2-methyltransferase | insig. | 31 | 46 |
| | Mycobacterium tuberculosis H37Rv | Rv0089 | | Possible methyltransferase/methylase | insig. | 33 | 44 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_05181 | | Trans-aconitate 2-methyltransferase | cofit | 31 | 46 |
| | Rahnella sp. WP5 | EX31_RS04120 | | 16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC | cofit | 28 | 46 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS19700 | | methyltransferase | cofit | 28 | 64 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS12370 | | trans-aconitate methyltransferase | insig. | 32 | 36 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS17095 | | SAM-dependent methyltransferase | insig. | 33 | 42 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_13670 | bioC | malonyl-ACP O-methyltransferase BioC | no data | 32 | 43 |
| | Serratia liquefaciens MT49 | IAI46_19810 | | class I SAM-dependent methyltransferase | insig. | 32 | 45 |
| | Pseudomonas sp. RS175 | PFR28_00385 | | 23S rRNA (guanine(745)-N(1))-methyltransferase | insig. | 31 | 49 |
| | Enterobacter sp. TBS_079 | MPMX20_03533 | | Trans-aconitate 2-methyltransferase | insig. | 38 | 42 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS10935 | | SAM-dependent methyltransferase | no data | 35 | 42 |
| | Ralstonia solanacearum UW163 | UW163_RS02645 | | SAM-dependent methyltransferase | no data | 35 | 42 |
| | Azospirillum sp. SherDot2 | MPMX19_02121 | | putative trans-aconitate 2-methyltransferase | insig. | 33 | 42 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3070 | | Ribosomal RNA large subunit methyltransferase A (EC 2.1.1.51) | insig. | 31 | 49 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1480 | | SAM-dependent methyltransferases | insig. | 29 | 72 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS06060 | | class I SAM-dependent methyltransferase | insig. | 28 | 57 |
| | Pseudomonas stutzeri RCH2 | Psest_0414 | | biotin biosynthesis protein BioC | strong | 35 | 43 |
| | Pseudomonas sp. SVBP6 | COO64_RS10775 | | trans-aconitate 2-methyltransferase | insig. | 31 | 45 |
| | Ralstonia solanacearum GMI1000 | RS_RS01775 | | SAM-dependent methyltransferase | no data | 35 | 42 |
| | Pseudomonas sp. DMC3 | GFF2041 | | 23S rRNA (guanine(745)-N(1))-methyltransferase | cofit | 31 | 49 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS06535 | | methyltransferase domain-containing protein | cofit | 30 | 57 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3579 | | 16S RNA G1207 methylase RsmC | insig. | 26 | 63 |
| | Escherichia fergusonii Becca | EFB2_01940 | | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | insig. | 35 | 32 |
| | Escherichia coli ECOR38 | HEPCGN_03565 | irp1 | yersiniabactin biosynthetic protein Irp1 | insig. | 35 | 32 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4722 | | Ribosomal RNA large subunit methyltransferase A (EC 2.1.1.51) | insig. | 31 | 48 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS09880 | | malonyl-ACP O-methyltransferase BioC | no data | 29 | 67 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS10240 | | malonyl-ACP O-methyltransferase BioC | no data | 29 | 67 |
| | Variovorax sp. OAS795 | ABID97_RS28555 | | methyltransferase domain-containing protein | insig. | 26 | 68 |
| | Sphingobium sp. HT1-2 | GFF2407 | | Malonyl-[acyl-carrier protein] O-methyltransferase (EC 2.1.1.197) | cofit | 38 | 34 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02572 | | methyltransferase domain protein | sig. | 28 | 50 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4251 | | Methylase involved in ubiquinone/menaquinone biosynthesis | insig. | 28 | 53 |
| | Azospirillum brasilense Sp245 | AZOBR_RS03890 | | methyltransferase UbiE | insig. | 26 | 62 |
| | Pseudomonas orientalis W4I3 | QF045_RS27340 | | trans-aconitate 2-methyltransferase | insig. | 29 | 46 |
| | Shewanella amazonensis SB2B | Sama_3312 | | hypothetical protein (RefSeq) | insig. | 28 | 51 |
| | Sinorhizobium meliloti 1021 | SM_b21410 | | methyltransferase, S-adenosyl-L-methionine (SAM)-MTase | insig. | 31 | 63 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0867 | | biotin biosynthesis protein BioC | no data | 31 | 42 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS06215 | | methyltransferase domain-containing protein | insig. | 29 | 49 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS06215 | | methyltransferase domain-containing protein | insig. | 29 | 49 |
| | Rhizobium sp. OAE497 | ABIE40_RS29210 | | class I SAM-dependent methyltransferase | insig. | 28 | 51 |
| | Azospirillum sp. SherDot2 | MPMX19_04629 | | D-inositol-3-phosphate glycosyltransferase | insig. | 34 | 35 |
| | Pseudomonas sp. SVBP6 | COO64_RS07620 | tam | trans-aconitate 2-methyltransferase | insig. | 28 | 46 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS22375 | | SAM-dependent methyltransferase | no data | 34 | 42 |
| | Marinobacter adhaerens HP15 | HP15_2483 | | protein containing methyltransferase type 11 domain | insig. | 33 | 49 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1031 | | Ribosomal RNA small subunit methyltransferase C (EC 2.1.1.52) | cofit | 32 | 33 |
| | Methylophilus sp. DMC18 | GFF724 | | Cyclopropane-fatty-acyl-phospholipid synthase | insig. | 30 | 42 |
| | Pseudomonas simiae WCS417 | PS417_06150 | | SAM-dependent methlyltransferase | sig. | 29 | 49 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_16405 | | SAM-dependent methyltransferase | insig. | 29 | 49 |
| | Serratia liquefaciens MT49 | IAI46_06465 | | class I SAM-dependent methyltransferase | insig. | 26 | 71 |
| | Pseudomonas sp. SVBP6 | COO64_RS19580 | | putative RNA methyltransferase | insig. | 39 | 26 |
| | Escherichia coli BL21 | ECD_01476 | | trans-aconitate methyltransferase | no data | 33 | 42 |
| | Escherichia coli BW25113 | b1519 | tam | trans-aconitate 2-methyltransferase (NCBI) | insig. | 33 | 42 |
| | Klebsiella michiganensis M5al | BWI76_RS15170 | | trans-aconitate 2-methyltransferase | no data | 31 | 46 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS05210 | | tRNA methyltransferase | insig. | 31 | 31 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS03020 | | malonyl-ACP O-methyltransferase BioC | no data | 30 | 50 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_3084 | | Ribosomal RNA large subunit methyltransferase A (EC 2.1.1.51) | insig. | 29 | 49 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS13885 | | methyltransferase domain-containing protein | no data | 34 | 42 |
| | Escherichia coli ECRC100 | OKFHMN_01140 | tam | trans-aconitate 2-methyltransferase | no data | 33 | 42 |
| | Escherichia coli ECRC101 | MCAODC_16785 | tam | trans-aconitate 2-methyltransferase | insig. | 33 | 42 |
| | Escherichia coli ECRC102 | NIAGMN_25285 | tam | trans-aconitate 2-methyltransferase | insig. | 33 | 42 |
| | Escherichia coli ECRC99 | KEDOAH_27290 | tam | trans-aconitate 2-methyltransferase | no data | 33 | 42 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS08520 | | 16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC | cofit | 27 | 63 |
| | Pseudomonas orientalis W4I3 | QF045_RS08995 | | methyltransferase domain-containing protein | insig. | 29 | 49 |
| | Lysobacter sp. OAE881 | ABIE51_RS14960 | | class I SAM-dependent methyltransferase | insig. | 29 | 56 |
| | Pantoea sp. MT58 | IAI47_16375 | | 16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC | sig. | 27 | 76 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0664 | | Methylase involved in ubiquinone/menaquinone biosynthesis | insig. | 26 | 69 |
| | Escherichia coli ECOR27 | NOLOHH_18790 | tam | trans-aconitate 2-methyltransferase | no data | 33 | 42 |
| | Escherichia coli ECOR38 | HEPCGN_26620 | tam | trans-aconitate 2-methyltransferase | insig. | 33 | 42 |
| | Escherichia coli ECRC62 | BNILDI_17270 | tam | trans-aconitate 2-methyltransferase | insig. | 33 | 42 |
| | Pseudomonas sp. SVBP6 | COO64_RS22710 | bioC | malonyl-ACP O-methyltransferase BioC | strong | 32 | 47 |
| | Klebsiella michiganensis M5al | BWI76_RS04080 | | 16S rRNA (guanine(1207)-N(2))-methyltransferase | strong | 30 | 42 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS08675 | | trans-aconitate 2-methyltransferase | no data | 33 | 42 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_06095 | | SAM-dependent methyltransferase | insig. | 29 | 49 |
| | Rhizobium sp. OAE497 | ABIE40_RS03460 | | SAM-dependent methyltransferase | insig. | 28 | 45 |
| | Pectobacterium carotovorum WPP14 | HER17_RS11885 | | carboxy-S-adenosyl-L-methionine synthase CmoA | cofit | 24 | 75 |
| | Escherichia fergusonii Becca | EFB2_02441 | | Trans-aconitate 2-methyltransferase | insig. | 33 | 42 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS04375 | | class I SAM-dependent methyltransferase | insig. | 30 | 51 |
| | Enterobacter sp. TBS_079 | MPMX20_00669 | | Ribosomal RNA small subunit methyltransferase C | insig. | 29 | 42 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2743 | | Methyltransferase domain | insig. | 34 | 42 |
| | Shewanella loihica PV-4 | Shew_3230 | | rRNA (guanine-N(2)-)-methyltransferase (RefSeq) | cofit | 30 | 43 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF5086 | | Trans-aconitate 2-methyltransferase (EC 2.1.1.144) | insig. | 30 | 40 |
| | Rhodopseudomonas palustris CGA009 | TX73_018685 | | trans-aconitate 2-methyltransferase | sig. | 37 | 30 |
| | Enterobacter sp. TBS_079 | MPMX20_02284 | | Trans-aconitate 2-methyltransferase | sig. | 32 | 33 |
| | Rhodospirillum rubrum S1H | Rru_A1457 | | O-methyltransferase, family 2 (NCBI) | insig. | 29 | 45 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS03520 | | class I SAM-dependent methyltransferase | insig. | 28 | 43 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3208 | | Methylase involved in ubiquinone/menaquinone biosynthesis | insig. | 27 | 59 |
| | Pseudomonas sp. RS175 | PFR28_00315 | | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | insig. | 31 | 41 |
| | Pseudomonas sp. RS175 | PFR28_05234 | | tRNA 5-carboxymethoxyuridine methyltransferase | insig. | 38 | 30 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01400 | | 23S rRNA (guanine(745)-N(1))-methyltransferase | insig. | 28 | 46 |
| | Sinorhizobium meliloti 1021 | SM_b20059 | | SAM-dependent methyltransferase | insig. | 27 | 48 |
| | Dechlorosoma suillum PS | Dsui_0380 | | hypothetical protein | insig. | 31 | 46 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS19000 | | polyketide synthase | insig. | 30 | 45 |
| | Ralstonia solanacearum UW163 | UW163_RS20130 | | polyketide synthase | insig. | 30 | 45 |
| | Cellulophaga baltica 18 | M666_RS17740 | | peptide chain release factor N(5)-glutamine methyltransferase | strong | 29 | 34 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS11760 | | methyltransferase domain-containing protein | insig. | 30 | 42 |
| | Pseudomonas sp. BP01 | JOY50_RS15705 | | methyltransferase | insig. | 29 | 48 |