Conservation of cofitness between PP_4922 and PP_1426 in Pseudomonas putida KT2440

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_4922 Phosphomethylpyrimidine synthase 1.0 PP_1426 L-aspartate oxidase 0.57 10
Pseudomonas sp. RS175 0.92 PFR28_05091 Phosphomethylpyrimidine synthase 0.89 PFR28_00689 L-aspartate oxidase 0.45 23
Pseudomonas fluorescens FW300-N2E2 0.92 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.85 Pf6N2E2_2758 L-aspartate oxidase (EC 1.4.3.16) low > 103
Pseudomonas fluorescens FW300-N2C3 0.92 AO356_08810 thiamine biosynthesis protein ThiC 0.88 AO356_04580 L-aspartate oxidase low > 104
Pseudomonas syringae pv. syringae B728a 0.92 Psyr_0544 hydroxymethylpyrimidine synthase 0.89 Psyr_3959 L-aspartate oxidase 0.55 42
Pseudomonas fluorescens SBW25-INTG 0.92 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.90 PFLU_RS07225 L-aspartate oxidase low > 109
Pseudomonas syringae pv. syringae B728a ΔmexB 0.92 Psyr_0544 hydroxymethylpyrimidine synthase 0.89 Psyr_3959 L-aspartate oxidase low > 86
Pseudomonas fluorescens SBW25 0.92 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.90 PFLU_RS07225 L-aspartate oxidase low > 109
Pseudomonas fluorescens GW456-L13 0.92 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.89 PfGW456L13_4517 L-aspartate oxidase (EC 1.4.3.16) low > 87
Pseudomonas fluorescens FW300-N2E3 0.92 AO353_13010 thiamine biosynthesis protein ThiC 0.90 AO353_17620 L-aspartate oxidase low > 101
Pseudomonas simiae WCS417 0.91 PS417_02355 thiamine biosynthesis protein ThiC 0.90 PS417_07115 L-aspartate oxidase low > 88
Pseudomonas fluorescens FW300-N1B4 0.91 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.89 Pf1N1B4_3322 L-aspartate oxidase (EC 1.4.3.16) low > 87
Pseudomonas sp. S08-1 0.91 OH686_15885 phosphomethylpyrimidine synthase 0.87 OH686_20040 L-aspartate oxidase low > 80
Pseudomonas stutzeri RCH2 0.90 Psest_0477 thiamine biosynthesis protein ThiC 0.86 Psest_3101 L-aspartate oxidase 0.32 34
Marinobacter adhaerens HP15 0.83 HP15_453 thiamine biosynthesis protein thiC 0.72 HP15_774 L-aspartate oxidase 0.63 57
Paraburkholderia sabiae LMG 24235 0.78 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.65 QEN71_RS03070 L-aspartate oxidase 0.83 15
Herbaspirillum seropedicae SmR1 0.78 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.63 HSERO_RS11085 L-aspartate oxidase 0.38 31
Dechlorosoma suillum PS 0.77 Dsui_0422 thiamine biosynthesis protein ThiC 0.64 Dsui_2452 L-aspartate oxidase
Acinetobacter radioresistens SK82 0.77 MPMX26_00180 Phosphomethylpyrimidine synthase 0.64 MPMX26_02162 L-aspartate oxidase low > 36
Paraburkholderia graminis OAS925 0.77 ABIE53_002857 phosphomethylpyrimidine synthase 0.65 ABIE53_003292 L-aspartate oxidase 0.35 101
Paraburkholderia bryophila 376MFSha3.1 0.77 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.65 H281DRAFT_04069 L-aspartate oxidase low > 103
Burkholderia phytofirmans PsJN 0.77 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.64 BPHYT_RS15640 L-aspartate oxidase 0.49 83
Pontibacter actiniarum KMM 6156, DSM 19842 0.76 CA264_20435 phosphomethylpyrimidine synthase ThiC 0.13 CA264_10795 succinate dehydrogenase flavoprotein subunit
Mucilaginibacter yixingensis YX-36 DSM 26809 0.75 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.44 ABZR88_RS20645 L-aspartate oxidase
Castellaniella sp019104865 MT123 0.75 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.57 ABCV34_RS03690 L-aspartate oxidase low > 48
Pedobacter sp. GW460-11-11-14-LB5 0.75 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.45 CA265_RS21185 L-aspartate oxidase low > 88
Pectobacterium carotovorum WPP14 0.74 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.65 HER17_RS05775 L-aspartate oxidase 0.75 74
Ralstonia sp. UNC404CL21Col 0.74 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.64 ABZR87_RS00345 L-aspartate oxidase 0.61 20
Echinicola vietnamensis KMM 6221, DSM 17526 0.74 Echvi_3567 thiamine biosynthesis protein ThiC 0.12 Echvi_2795 succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup
Ralstonia solanacearum PSI07 0.74 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.64 RPSI07_RS12660 L-aspartate oxidase low > 81
Ralstonia solanacearum IBSBF1503 0.74 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.64 RALBFv3_RS04725 L-aspartate oxidase low > 76
Ralstonia solanacearum UW163 0.74 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.64 UW163_RS08945 L-aspartate oxidase
Shewanella loihica PV-4 0.74 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.66 Shew_1047 L-aspartate oxidase (RefSeq)
Ralstonia solanacearum GMI1000 0.74 RS_RS00555 phosphomethylpyrimidine synthase 0.64 RS_RS12285 L-aspartate oxidase low > 80
Pantoea sp. MT58 0.73 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.64 IAI47_04845 L-aspartate oxidase low > 76
Dickeya dadantii 3937 0.73 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.66 DDA3937_RS15770 L-aspartate oxidase 0.81 23
Cupriavidus basilensis FW507-4G11 0.73 RR42_RS01290 thiamine biosynthesis protein ThiC 0.64 RR42_RS17010 L-aspartate oxidase low > 128
Rahnella sp. WP5 0.73 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.64 EX31_RS21795 L-aspartate oxidase low > 89
Serratia liquefaciens MT49 0.73 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.66 IAI46_19590 L-aspartate oxidase low > 86
Escherichia coli ECRC62 0.72 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.64 BNILDI_11845 nadB L-aspartate oxidase
Escherichia coli HS(pFamp)R (ATCC 700891) 0.72 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.64 OHPLBJKB_01133 L-aspartate oxidase low > 73
Escherichia coli BW25113 0.72 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.64 b2574 nadB L-aspartate oxidase (NCBI) 0.58 14
Escherichia coli ECOR27 0.72 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.64 NOLOHH_13045 nadB L-aspartate oxidase low > 57
Escherichia coli Nissle 1917 0.72 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.64 ECOLIN_RS14570 L-aspartate oxidase low > 52
Escherichia fergusonii Becca 0.72 EFB2_04617 Phosphomethylpyrimidine synthase 0.63 EFB2_01322 L-aspartate oxidase low > 86
Shewanella amazonensis SB2B 0.72 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.67 Sama_0873 L-aspartate oxidase (RefSeq)
Escherichia coli ECRC101 0.72 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.64 OKFHMN_21370 nadB L-aspartate oxidase
Escherichia coli ECRC102 0.72 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.64 NIAGMN_19140 nadB L-aspartate oxidase
Escherichia coli ECRC101 0.72 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.64 MCAODC_11900 nadB L-aspartate oxidase
Dickeya dianthicola 67-19 0.72 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.66 HGI48_RS15855 L-aspartate oxidase 0.74 67
Escherichia coli ECRC98 0.72 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.64 JDDGAC_25035 nadB L-aspartate oxidase
Escherichia coli ECRC99 0.72 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.64 KEDOAH_06850 nadB L-aspartate oxidase
Kangiella aquimarina DSM 16071 0.72 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.67 B158DRAFT_2179 L-aspartate oxidase (EC 1.4.3.16) low > 40
Dickeya dianthicola ME23 0.72 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.65 DZA65_RS16935 L-aspartate oxidase 0.88 5
Enterobacter sp. TBS_079 0.72 MPMX20_00217 Phosphomethylpyrimidine synthase 0.64 MPMX20_03445 L-aspartate oxidase low > 85
Escherichia coli BL21 0.72 ECD_03871 phosphomethylpyrimidine synthase 0.64 ECD_02468 quinolinate synthase, L-aspartate oxidase (B protein) subunit low > 60
Escherichia coli ECOR38 0.72 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.64 HEPCGN_20515 nadB L-aspartate oxidase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.72 GFF4198 Thiamin biosynthesis protein ThiC 0.64 GFF2106 L-aspartate oxidase (EC 1.4.3.16) low > 78
Enterobacter asburiae PDN3 0.72 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.64 EX28DRAFT_0071 L-aspartate oxidase (EC 1.4.3.16) 0.73 2
Klebsiella michiganensis M5al 0.71 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.64 BWI76_RS21360 L-aspartate oxidase 0.64 6
Alteromonas macleodii MIT1002 0.71 MIT1002_00097 Phosphomethylpyrimidine synthase 0.61 MIT1002_02720 L-aspartate oxidase
Vibrio cholerae E7946 ATCC 55056 0.71 CSW01_00335 phosphomethylpyrimidine synthase 0.67 CSW01_12495 L-aspartate oxidase low > 62
Shewanella oneidensis MR-1 0.71 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.66 SO1341 nadB L-aspartate oxidase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.70 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.66 Shewana3_3033 L-aspartate oxidase (RefSeq)
Variovorax sp. SCN45 0.69 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.62 GFF2580 L-aspartate oxidase (EC 1.4.3.16) low > 127
Magnetospirillum magneticum AMB-1 0.69 AMB_RS01125 phosphomethylpyrimidine synthase 0.60 AMB_RS19650 L-aspartate oxidase
Variovorax sp. OAS795 0.68 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.59 ABID97_RS07440 L-aspartate oxidase low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.68 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.61 GFF1214 L-aspartate oxidase (EC 1.4.3.16) low > 90
Acidovorax sp. GW101-3H11 0.67 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.57 Ac3H11_3824 L-aspartate oxidase (EC 1.4.3.16) 0.67 52
Azospirillum brasilense Sp245 0.67 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.20 AZOBR_RS18685 L-aspartate oxidase low > 97
Caulobacter crescentus NA1000 0.66 CCNA_02109 thiamine biosynthesis protein thiC 0.21 CCNA_03007 L-aspartate oxidase
Caulobacter crescentus NA1000 Δfur 0.66 CCNA_02109 thiamine biosynthesis protein thiC 0.21 CCNA_03007 L-aspartate oxidase
Agrobacterium fabrum C58 0.65 Atu2569 thiamine biosynthesis protein 0.25 Atu4097 L-aspartate oxidase 0.82 7
Sinorhizobium meliloti 1021 0.65 SM_b20615 thiamine biosynthesis protein ThiC 0.29 SMc02599 L-aspartate oxidase low > 103
Rhodopseudomonas palustris CGA009 0.65 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.25 TX73_005420 L-aspartate oxidase
Azospirillum sp. SherDot2 0.64 MPMX19_00336 Phosphomethylpyrimidine synthase 0.26 MPMX19_05671 L-aspartate oxidase low > 112
Sphingomonas koreensis DSMZ 15582 0.64 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.56 Ga0059261_2248 L-aspartate oxidase (EC 1.4.3.16)
Brevundimonas sp. GW460-12-10-14-LB2 0.63 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.21 A4249_RS00630 L-aspartate oxidase low > 48
Rhodospirillum rubrum S1H 0.61 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.25 Rru_A1433 L-aspartate oxidase (NCBI) low > 58
Parabacteroides merdae CL09T00C40 0.58 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC 0.44 HMPREF1078_RS06605 L-aspartate oxidase
Bacteroides ovatus ATCC 8483 0.58 BACOVA_02358 thiamine biosynthesis protein ThiC 0.43 BACOVA_02888 L-aspartate oxidase 0.78 25
Bacteroides thetaiotaomicron VPI-5482 0.58 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.44 BT3184 L-aspartate oxidase (NCBI ptt file) 0.46 14
Phocaeicola dorei CL03T12C01 0.58 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.45 ABI39_RS05945 L-aspartate oxidase
Phocaeicola vulgatus CL09T03C04 0.58 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.44 HMPREF1058_RS11085 L-aspartate oxidase
Bacteroides stercoris CC31F 0.58 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.44 HMPREF1181_RS01800 L-aspartate oxidase
Mycobacterium tuberculosis H37Rv 0.53 Rv0423c Probable thiamine biosynthesis protein ThiC 0.25 Rv1595 Probable L-aspartate oxidase NadB

Not shown: 8 genomes with orthologs for PP_4922 only; 6 genomes with orthologs for PP_1426 only