Conservation of cofitness between HER17_RS12840 and HER17_RS20400 in Pectobacterium carotovorum WPP14

83 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS12840 LysR family transcriptional regulator 1.0 HER17_RS20400 thiazole synthase 0.88 1
Dickeya dianthicola 67-19 0.84 HGI48_RS09285 LysR family transcriptional regulator 0.85 HGI48_RS01150 thiazole synthase low > 71
Dickeya dadantii 3937 0.83 DDA3937_RS09260 LysR family transcriptional regulator 0.85 DDA3937_RS01155 thiazole synthase low > 74
Dickeya dianthicola ME23 0.83 DZA65_RS09590 LysR family transcriptional regulator 0.85 DZA65_RS01195 thiazole synthase low > 75
Serratia liquefaciens MT49 0.82 IAI46_17215 LysR family transcriptional regulator 0.82 IAI46_01300 thiazole synthase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.80 GFF3777 LysR family transcriptional regulator YeiE 0.75 GFF4202 Thiazole biosynthesis protein ThiG low > 78
Escherichia coli ECRC98 0.79 JDDGAC_27455 yieE DNA-binding transcriptional regulator YeiE 0.75 JDDGAC_17020 thiG thiazole synthase low > 86
Escherichia coli ECRC102 0.79 NIAGMN_21260 yieE DNA-binding transcriptional regulator YeiE 0.75 NIAGMN_11145 thiG thiazole synthase
Escherichia coli HS(pFamp)R (ATCC 700891) 0.79 OHPLBJKB_01554 HTH-type transcriptional regulator CysL 0.75 OHPLBJKB_04060 Thiazole synthase low > 73
Escherichia coli ECRC100 0.79 OKFHMN_23495 yieE DNA-binding transcriptional regulator YeiE 0.75 OKFHMN_13395 thiG thiazole synthase low > 80
Enterobacter asburiae PDN3 0.79 EX28DRAFT_0399 Transcriptional regulator 0.76 EX28DRAFT_4532 Uncharacterized enzyme of thiazole biosynthesis low > 76
Escherichia coli ECOR38 0.79 HEPCGN_22760 yieE DNA-binding transcriptional regulator YeiE 0.75 HEPCGN_12030 thiG thiazole synthase low > 87
Escherichia coli ECRC62 0.79 BNILDI_13990 yieE DNA-binding transcriptional regulator YeiE 0.75 BNILDI_05985 thiG thiazole synthase low > 75
Escherichia coli ECRC99 0.79 KEDOAH_04690 yieE DNA-binding transcriptional regulator YeiE 0.75 KEDOAH_14765 thiG thiazole synthase
Escherichia coli ECRC101 0.79 MCAODC_14545 yieE DNA-binding transcriptional regulator YeiE 0.75 MCAODC_03895 thiG thiazole synthase low > 87
Escherichia coli Nissle 1917 0.79 ECOLIN_RS12630 DNA-binding transcriptional regulator YeiE 0.75 ECOLIN_RS23020 thiazole synthase low > 55
Escherichia coli BL21 0.79 ECD_02086 putative DNA-binding transcriptional regulator 0.75 ECD_03867 thiamine biosynthesis ThiGH complex subunit low > 61
Escherichia coli BW25113 0.79 b2157 yeiE predicted DNA-binding transcriptional regulator (NCBI) 0.76 b3991 thiG thiamin biosynthesis, thiazole moiety (VIMSS) low > 76
Rahnella sp. WP5 0.78 EX31_RS19050 LysR family transcriptional regulator 0.80 EX31_RS16795 thiazole synthase low > 89
Enterobacter sp. TBS_079 0.78 MPMX20_03128 HTH-type transcriptional activator CmpR 0.76 MPMX20_00213 Thiazole synthase low > 85
Klebsiella michiganensis M5al 0.78 BWI76_RS19690 LysR family transcriptional regulator 0.76 BWI76_RS01535 thiazole synthase low > 92
Pantoea sp. MT58 0.75 IAI47_06680 LysR family transcriptional regulator 0.37 IAI47_20700 thiazole synthase low > 76
Erwinia tracheiphila SCR3 0.74 LU632_RS17295 LysR family transcriptional regulator 0.76 LU632_RS00950 thiazole synthase low > 74
Escherichia coli ECOR27 0.71 NOLOHH_15070 yieE DNA-binding transcriptional regulator YeiE 0.75 NOLOHH_05540 thiG thiazole synthase low > 75
Escherichia fergusonii Becca 0.71 EFB2_01699 HTH-type transcriptional regulator CysL 0.75 EFB2_04621 Thiazole synthase low > 86
Pseudomonas sp. S08-1 0.47 OH686_18820 Transcriptional regulator, LysR family 0.40 OH686_14285 Thiazole synthase low > 80
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_3312 transcriptional regulator, LysR family 0.39 Psyr_4740 thiazole-phosphate synthase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_3312 transcriptional regulator, LysR family 0.39 Psyr_4740 thiazole-phosphate synthase low > 86
Pseudomonas fluorescens SBW25 0.45 PFLU_RS09365 LysR family transcriptional regulator 0.40 PFLU_RS28420 thiazole synthase low > 109
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS09365 LysR family transcriptional regulator 0.40 PFLU_RS28420 thiazole synthase low > 109
Cupriavidus basilensis FW507-4G11 0.45 RR42_RS13965 LysR family transcriptional regulator 0.39 RR42_RS01305 thiazole synthase
Pseudomonas putida KT2440 0.45 PP_1637 Transcriptional regulator, LysR family 0.39 PP_5104 thiazole synthase low > 96
Pseudomonas fluorescens FW300-N2E3 0.44 AO353_16845 LysR family transcriptional regulator 0.40 AO353_08215 thiazole synthase low > 101
Pseudomonas fluorescens FW300-N1B4 0.44 Pf1N1B4_3152 LysR family transcriptional regulator PA3398 0.39 Pf1N1B4_2331 Thiazole biosynthesis protein ThiG low > 87
Ralstonia sp. UNC404CL21Col 0.44 ABZR87_RS10365 LysR family transcriptional regulator 0.41 ABZR87_RS04800 thiazole synthase
Pseudomonas fluorescens FW300-N2E2 0.44 Pf6N2E2_2984 LysR family transcriptional regulator PA3398 0.39 Pf6N2E2_4590 Thiazole biosynthesis protein ThiG low > 103
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS14705 LysR family transcriptional regulator 0.41 RALBFv3_RS09925 thiazole synthase
Pseudomonas fluorescens FW300-N2C3 0.44 AO356_05630 LysR family transcriptional regulator 0.39 AO356_13375 thiazole synthase low > 104
Ralstonia solanacearum UW163 0.44 UW163_RS12175 LysR family transcriptional regulator 0.41 UW163_RS03655 thiazole synthase
Pseudomonas sp. RS175 0.44 PFR28_00480 HTH-type transcriptional activator CmpR 0.40 PFR28_04252 Thiazole synthase low > 88
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS21575 transcriptional regulator 0.40 HSERO_RS02130 thiazole synthase low > 78
Pseudomonas stutzeri RCH2 0.44 Psest_2863 Transcriptional regulator 0.41 Psest_0267 Uncharacterized enzyme of thiazole biosynthesis low > 67
Ralstonia solanacearum PSI07 0.44 RPSI07_RS18655 LysR family transcriptional regulator 0.40 RPSI07_RS23435 thiazole synthase
Ralstonia solanacearum GMI1000 0.43 RS_RS05515 LysR family transcriptional regulator 0.40 RS_RS00535 thiazole synthase
Xanthomonas campestris pv. campestris strain 8004 0.43 Xcc-8004.979.1 LysR family transcriptional regulator YeiE 0.43 Xcc-8004.1284.1 Thiazole biosynthesis protein ThiG low > 74
Pseudomonas simiae WCS417 0.43 PS417_05850 LysR family transcriptional regulator 0.40 PS417_26775 thiazole synthase low > 88
Variovorax sp. SCN45 0.42 GFF3160 Transcriptional regulator YeiE, LysR family 0.38 GFF1188 Thiazole synthase (EC 2.8.1.10) low > 127
Pseudomonas fluorescens GW456-L13 0.41 PfGW456L13_4660 LysR family transcriptional regulator PA3398 0.40 PfGW456L13_1000 Thiazole biosynthesis protein ThiG low > 87
Acinetobacter radioresistens SK82 0.41 MPMX26_02541 HTH-type transcriptional regulator CysL 0.37 MPMX26_01107 Thiazole synthase low > 36
Dechlorosoma suillum PS 0.40 Dsui_2257 transcriptional regulator 0.39 Dsui_1014 putative enzyme of thiazole biosynthesis
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF333 LysR family transcriptional regulator YeiE 0.37 GFF246 Thiazole biosynthesis protein ThiG
Vibrio cholerae E7946 ATCC 55056 0.35 CSW01_11795 LysR family transcriptional regulator 0.67 CSW01_00355 thiazole synthase low > 62
Marinobacter adhaerens HP15 0.35 HP15_2201 transcriptional regulator, LysR family 0.43 HP15_3274 thiazole synthase
Shewanella loihica PV-4 0.34 Shew_2531 LysR family transcriptional regulator (RefSeq) 0.64 Shew_2092 thiazole biosynthesis family protein (RefSeq) low > 60
Castellaniella sp019104865 MT123 0.34 ABCV34_RS05920 LysR substrate-binding domain-containing protein 0.41 ABCV34_RS14510 thiazole synthase
Rhodanobacter sp. FW510-T8 0.33 OKGIIK_02230 lysR LysR family transcriptional regulator 0.43 OKGIIK_11895 thiS thiazole synthase low > 52
Dyella japonica UNC79MFTsu3.2 0.33 ABZR86_RS19780 LysR family transcriptional regulator 0.43 ABZR86_RS11645 thiazole synthase
Shewanella amazonensis SB2B 0.33 Sama_1882 LysR family transcriptional regulator (RefSeq) 0.69 Sama_1856 thiG thiazole synthase (RefSeq) low > 62
Shewanella oneidensis MR-1 0.30 SO2561 transcriptional regulator, LysR family (NCBI ptt file) 0.65 SO2441 thiG thiG protein (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.30 Shewana3_2367 LysR family transcriptional regulator (RefSeq) 0.65 Shewana3_1940 thiG thiazole synthase (RefSeq) low > 73
Rhodopseudomonas palustris CGA009 0.27 TX73_009100 LysR family transcriptional regulator 0.41 TX73_018530 thiazole synthase
Synechococcus elongatus PCC 7942 0.27 Synpcc7942_1310 cmpR ndhF3 operon transcriptional regulator 0.48 Synpcc7942_0576 thiG thiazole synthase
Desulfovibrio vulgaris Miyazaki F 0.26 DvMF_0108 transcriptional regulator, LysR family (RefSeq) 0.44 DvMF_0800 thiG thiazole synthase (RefSeq) low > 51
Brevundimonas sp. GW460-12-10-14-LB2 0.26 A4249_RS01115 LysR substrate-binding domain-containing protein 0.35 A4249_RS07975 thiazole synthase
Azospirillum sp. SherDot2 0.26 MPMX19_00813 HTH-type transcriptional regulator CysL 0.41 MPMX19_00262 Thiazole synthase low > 112
Azospirillum brasilense Sp245 0.25 AZOBR_RS32560 LysR family transcriptional regulator 0.39 AZOBR_RS30960 thiazole synthase
Paraburkholderia graminis OAS925 0.24 ABIE53_005077 DNA-binding transcriptional LysR family regulator 0.37 ABIE53_003714 thiazole synthase
Paraburkholderia bryophila 376MFSha3.1 0.24 H281DRAFT_03013 transcriptional regulator, LysR family 0.37 H281DRAFT_05639 thiazole-phosphate synthase
Agrobacterium fabrum C58 0.24 Atu0672 transcriptional regulator, LysR family 0.33 Atu2566 thiamin biosynthesis ThiG low > 89
Burkholderia phytofirmans PsJN 0.24 BPHYT_RS29890 LysR family transcriptional regulator 0.37 BPHYT_RS17775 thiazole synthase
Paraburkholderia sabiae LMG 24235 0.24 QEN71_RS34015 LysR family transcriptional regulator 0.38 QEN71_RS27930 thiazole synthase
Phocaeicola dorei CL03T12C01 0.23 ABI39_RS18875 LysR family transcriptional regulator 0.63 ABI39_RS17755 thiazole synthase low > 72
Mucilaginibacter yixingensis YX-36 DSM 26809 0.23 ABZR88_RS12590 LysR family transcriptional regulator 0.63 ABZR88_RS08825 thiazole synthase low > 71
Phocaeicola vulgatus CL09T03C04 0.23 HMPREF1058_RS04990 LysR family transcriptional regulator 0.62 HMPREF1058_RS03285 thiazole synthase low > 67
Desulfovibrio vulgaris Hildenborough JW710 0.23 DVU1331 transcriptional regulator, LysR family (TIGR) 0.45 DVU2094 thiG thiG protein (TIGR) low > 55
Bacteroides ovatus ATCC 8483 0.22 BACOVA_05396 LysR substrate binding domain protein 0.63 BACOVA_02359 thiazole biosynthesis protein ThiG low > 94
Bacteroides stercoris CC31F 0.22 HMPREF1181_RS11950 LysR family transcriptional regulator 0.65 HMPREF1181_RS14680 thiazole synthase low > 56
Variovorax sp. OAS795 0.21 ABID97_RS24450 LysR family transcriptional regulator 0.39 ABID97_RS15315 thiazole synthase low > 91
Pontibacter actiniarum KMM 6156, DSM 19842 0.21 CA264_07870 LysR family transcriptional regulator 0.66 CA264_20420 thiazole synthase low > 74
Echinicola vietnamensis KMM 6221, DSM 17526 0.20 Echvi_1204 Transcriptional regulator 0.65 Echvi_3564 Uncharacterized enzyme of thiazole biosynthesis low > 79
Bacteroides thetaiotaomicron VPI-5482 0.20 BT4599 putative transcriptional regulator (NCBI ptt file) 0.63 BT0651 thiamine biosynthesis protein ThiG (NCBI ptt file) low > 81
Sinorhizobium meliloti 1021 0.19 SM_b20203 transcriptional regulator 0.33 SM_b20617 thiazole synthase
Mycobacterium tuberculosis H37Rv 0.15 Rv2282c Probable transcription regulator (LysR family) 0.42 Rv0417 Probable thiamin biosynthesis protein ThiG (thiazole biosynthesis protein)
Bifidobacterium breve UCC2003 0.13 BBR_RS13510 LysR family transcriptional regulator 0.44 BBR_RS13965 thiazole synthase low > 34

Not shown: 7 genomes with orthologs for HER17_RS12840 only; 11 genomes with orthologs for HER17_RS20400 only