Conservation of cofitness between HER17_RS04200 and HER17_RS17630 in Pectobacterium carotovorum WPP14

81 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS04200 7-carboxy-7-deazaguanine synthase QueE 1.0 HER17_RS17630 acetate--CoA ligase 0.70 3
Serratia liquefaciens MT49 0.86 IAI46_03675 7-carboxy-7-deazaguanine synthase QueE 0.88 IAI46_01405 acetate--CoA ligase low > 86
Dickeya dadantii 3937 0.86 DDA3937_RS16970 7-carboxy-7-deazaguanine synthase QueE 0.91 DDA3937_RS03480 acetate--CoA ligase low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF4831 Queuosine Biosynthesis QueE Radical SAM 0.85 GFF1452 Acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 78
Escherichia coli ECRC99 0.85 KEDOAH_07830 queE 7-carboxy-7-deazaguanine synthase QueE 0.86 KEDOAH_15320 acs acetate--CoA ligase — —
Escherichia coli BW25113 0.85 b2777 ygcF hypothetical protein (NCBI) 0.86 b4069 acs acetyl-coenzyme A synthetase (NCBI) low > 76
Escherichia coli ECRC62 0.85 BNILDI_10675 queE 7-carboxy-7-deazaguanine synthase QueE 0.86 BNILDI_06445 acs acetate--CoA ligase low > 75
Escherichia coli ECRC102 0.85 NIAGMN_18070 queE 7-carboxy-7-deazaguanine synthase QueE 0.86 NIAGMN_10675 acs acetate--CoA ligase — —
Escherichia coli ECRC100 0.85 OKFHMN_20300 queE 7-carboxy-7-deazaguanine synthase QueE 0.86 OKFHMN_12830 acs acetate--CoA ligase low > 80
Escherichia coli ECRC101 0.85 MCAODC_10825 queE 7-carboxy-7-deazaguanine synthase QueE 0.86 MCAODC_03340 acs acetate--CoA ligase low > 87
Klebsiella michiganensis M5al 0.85 BWI76_RS22780 7-carboxy-7-deazaguanine synthase QueE 0.86 BWI76_RS02095 acetyl-coenzyme A synthetase low > 92
Escherichia coli BL21 0.85 ECD_02622 7-carboxy-7-deazaguanine synthase; queosine biosynthesis 0.86 ECD_03941 acetyl-CoA synthetase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.85 OHPLBJKB_00957 7-carboxy-7-deazaguanine synthase 0.86 OHPLBJKB_03971 Acetyl-coenzyme A synthetase low > 73
Escherichia coli ECRC98 0.85 JDDGAC_23965 queE 7-carboxy-7-deazaguanine synthase QueE 0.86 JDDGAC_16465 acs acetate--CoA ligase 0.49 68
Escherichia coli ECOR27 0.85 NOLOHH_12170 queE 7-carboxy-7-deazaguanine synthase QueE 0.86 NOLOHH_05080 acs acetate--CoA ligase low > 75
Escherichia coli Nissle 1917 0.85 ECOLIN_RS15475 7-carboxy-7-deazaguanine synthase QueE 0.85 ECOLIN_RS23550 acetate--CoA ligase low > 55
Escherichia coli ECOR38 0.85 HEPCGN_19205 queE 7-carboxy-7-deazaguanine synthase QueE 0.86 HEPCGN_11455 acs acetate--CoA ligase low > 87
Escherichia fergusonii Becca 0.85 EFB2_01141 7-carboxy-7-deazaguanine synthase 0.85 EFB2_04520 Acetyl-coenzyme A synthetase low > 86
Enterobacter sp. TBS_079 0.84 MPMX20_03645 7-carboxy-7-deazaguanine synthase 0.85 MPMX20_00291 Acetyl-coenzyme A synthetase low > 85
Enterobacter asburiae PDN3 0.84 EX28DRAFT_2855 putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 0.85 EX28DRAFT_4232 acetate--CoA ligase low > 76
Erwinia tracheiphila SCR3 0.84 LU632_RS06390 queE 7-carboxy-7-deazaguanine synthase QueE 0.84 LU632_RS23305 acs acetate--CoA ligase low > 74
Rahnella sp. WP5 0.83 EX31_RS07920 7-carboxy-7-deazaguanine synthase QueE 0.85 EX31_RS09040 acetate--CoA ligase low > 89
Pantoea sp. MT58 0.80 IAI47_04140 7-carboxy-7-deazaguanine synthase QueE 0.83 IAI47_17715 acetate--CoA ligase low > 76
Dickeya dianthicola 67-19 0.79 HGI48_RS17035 7-carboxy-7-deazaguanine synthase QueE 0.90 HGI48_RS03580 acetate--CoA ligase low > 71
Dickeya dianthicola ME23 0.79 DZA65_RS18110 7-carboxy-7-deazaguanine synthase QueE 0.90 DZA65_RS03695 acetate--CoA ligase low > 75
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_06870 7-carboxy-7-deazaguanine synthase QueE 0.78 CSW01_01520 acetyl-coenzyme A synthetase low > 62
Shewanella sp. ANA-3 0.61 Shewana3_2163 radical activating enzyme (RefSeq) 0.71 Shewana3_2523 acetyl-CoA synthetase (RefSeq) low > 73
Shewanella loihica PV-4 0.61 Shew_2061 radical SAM domain-containing protein (RefSeq) 0.70 Shew_1533 acetyl-CoA synthetase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.60 SO2501 radical activating enzyme (NCBI ptt file) 0.71 SO2743 acs acetyl-coenzyme A synthetase (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.58 MIT1002_01264 7-carboxy-7-deazaguanine synthase 0.65 MIT1002_03516 Acetyl-coenzyme A synthetase low > 70
Shewanella amazonensis SB2B 0.58 Sama_1825 radical activating enzyme (RefSeq) 0.71 Sama_2079 acetyl-CoA synthetase (RefSeq) low > 62
Paraburkholderia sabiae LMG 24235 0.45 QEN71_RS41925 7-carboxy-7-deazaguanine synthase QueE 0.48 QEN71_RS23765 acetate--CoA ligase low > 153
Echinicola vietnamensis KMM 6221, DSM 17526 0.26 Echvi_4642 Organic radical activating enzymes 0.52 Echvi_1268 acetate--CoA ligase low > 79
Synechococcus elongatus PCC 7942 0.23 Synpcc7942_1332 hypothetical protein 0.51 Synpcc7942_1352 acsA acetyl-CoA synthetase low > 38
Mucilaginibacter yixingensis YX-36 DSM 26809 0.23 ABZR88_RS09380 7-carboxy-7-deazaguanine synthase QueE 0.52 ABZR88_RS15400 acetate--CoA ligase low > 71
Pedobacter sp. GW460-11-11-14-LB5 0.23 CA265_RS08930 7-carboxy-7-deazaguanine synthase QueE 0.53 CA265_RS16340 acetate--CoA ligase low > 88
Bacteroides thetaiotaomicron VPI-5482 0.22 BT4454 conserved hypothetical protein (NCBI ptt file) 0.15 BT3755 acetyl-coenzyme A synthetase (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.22 BACOVA_05261 radical SAM domain protein 0.15 BACOVA_03585 AMP-binding enzyme low > 94
Burkholderia phytofirmans PsJN 0.21 BPHYT_RS01505 7-cyano-7-deazaguanine reductase 0.47 BPHYT_RS07000 acetyl-CoA synthetase low > 109
Bacteroides stercoris CC31F 0.21 HMPREF1181_RS13885 radical SAM protein 0.14 HMPREF1181_RS03430 AMP-binding protein low > 56
Paraburkholderia graminis OAS925 0.21 ABIE53_000397 7-carboxy-7-deazaguanine synthase 0.47 ABIE53_001664 acetyl-CoA synthetase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.20 H281DRAFT_02231 7-carboxy-7-deazaguanine synthase, Cx14CxxC type 0.47 H281DRAFT_04953 acetyl-coenzyme A synthetase low > 103
Magnetospirillum magneticum AMB-1 0.20 AMB_RS01255 7-carboxy-7-deazaguanine synthase 0.68 AMB_RS21140 acetate--CoA ligase low > 64
Rhodospirillum rubrum S1H 0.19 Rru_A1959 Radical SAM (NCBI) 0.66 Rru_A3575 Acetate--CoA ligase (NCBI) low > 58
Phocaeicola vulgatus CL09T03C04 0.19 HMPREF1058_RS14880 radical SAM protein 0.14 HMPREF1058_RS08765 AMP-binding protein low > 67
Ralstonia sp. UNC404CL21Col 0.19 ABZR87_RS12145 7-carboxy-7-deazaguanine synthase 0.47 ABZR87_RS14360 acetate--CoA ligase low > 80
Azospirillum brasilense Sp245 0.19 AZOBR_RS04155 radical SAM protein 0.68 AZOBR_RS00270 acetyl-CoA synthetase low > 97
Cupriavidus basilensis FW507-4G11 0.18 RR42_RS11390 7-cyano-7-deazaguanine reductase 0.48 RR42_RS13880 AMP-dependent synthetase — —
Rhodopseudomonas palustris CGA009 0.18 TX73_006110 7-carboxy-7-deazaguanine synthase 0.67 TX73_001095 acetate--CoA ligase low > 86
Caulobacter crescentus NA1000 Δfur 0.18 CCNA_03261 queuosine biosynthesis protein QueE 0.59 CCNA_03696 acetyl-coenzyme A synthetase low > 67
Caulobacter crescentus NA1000 0.18 CCNA_03261 queuosine biosynthesis protein QueE 0.59 CCNA_03696 acetyl-coenzyme A synthetase low > 66
Pseudomonas simiae WCS417 0.18 PS417_22405 7-carboxy-7-deazaguanine synthase 0.71 PS417_21750 acetyl-CoA synthetase low > 88
Herbaspirillum seropedicae SmR1 0.18 HSERO_RS11035 7-cyano-7-deazaguanine reductase 0.46 HSERO_RS07770 acetyl-CoA synthetase low > 78
Pseudomonas fluorescens SBW25-INTG 0.18 PFLU_RS24045 7-carboxy-7-deazaguanine synthase QueE 0.71 PFLU_RS23355 acetate--CoA ligase low > 109
Pseudomonas fluorescens SBW25 0.18 PFLU_RS24045 7-carboxy-7-deazaguanine synthase QueE 0.71 PFLU_RS23355 acetate--CoA ligase low > 109
Parabacteroides merdae CL09T00C40 0.18 HMPREF1078_RS00750 radical SAM protein 0.14 HMPREF1078_RS10645 AMP-binding protein low > 61
Ralstonia solanacearum GMI1000 0.17 RS_RS07295 7-carboxy-7-deazaguanine synthase 0.47 RS_RS09815 acetyl-coenzyme A synthetase low > 80
Ralstonia solanacearum UW163 0.17 UW163_RS13945 7-carboxy-7-deazaguanine synthase 0.47 UW163_RS11280 acetate--CoA ligase — —
Ralstonia solanacearum IBSBF1503 0.17 RALBFv3_RS00615 7-carboxy-7-deazaguanine synthase 0.47 RALBFv3_RS02445 acetate--CoA ligase — —
Pseudomonas sp. RS175 0.17 PFR28_03404 7-carboxy-7-deazaguanine synthase 0.71 PFR28_03289 Acetyl-coenzyme A synthetase low > 88
Ralstonia solanacearum PSI07 0.17 RPSI07_RS16890 7-carboxy-7-deazaguanine synthase 0.47 RPSI07_RS14880 acetate--CoA ligase — —
Pseudomonas fluorescens FW300-N2C3 0.17 AO356_18065 7-carboxy-7-deazaguanine synthase 0.71 AO356_18695 Acetyl-coenzyme A synthetase (EC 6.2.1.1) (from data) low > 104
Pseudomonas fluorescens FW300-N2E2 0.17 Pf6N2E2_5545 Queuosine Biosynthesis QueE Radical SAM 0.71 Pf6N2E2_5659 Acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 103
Brevundimonas sp. GW460-12-10-14-LB2 0.17 A4249_RS08695 7-carboxy-7-deazaguanine synthase 0.62 A4249_RS15190 acetate--CoA ligase — —
Pseudomonas fluorescens FW300-N1B4 0.17 Pf1N1B4_629 Queuosine Biosynthesis QueE Radical SAM 0.71 Pf1N1B4_3430 Acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 87
Desulfovibrio vulgaris Hildenborough JW710 0.17 DVU2658 conserved hypothetical protein (TIGR) 0.55 DVU2969 acetoacetyl-CoA synthase (TIGR) low > 55
Desulfovibrio vulgaris Miyazaki F 0.17 DvMF_1124 radical SAM domain protein (RefSeq) 0.54 DvMF_1775 acetate/CoA ligase (RefSeq) low > 51
Pseudomonas fluorescens FW300-N2E3 0.17 AO353_03540 7-carboxy-7-deazaguanine synthase 0.71 AO353_03060 Acetyl-coenzyme A synthetase (EC 6.2.1.1) (from data) low > 101
Variovorax sp. SCN45 0.17 GFF2577 7-carboxy-7-deazaguanine synthase (EC 4.3.99.3) 0.46 GFF6925 Acetyl-CoA synthetase (EC 6.2.1.1) — —
Pseudomonas sp. S08-1 0.17 OH686_19175 7-carboxy-7-deazaguanine synthase 0.72 OH686_21250 acetate--CoA ligase low > 80
Dyella japonica UNC79MFTsu3.2 0.16 ABZR86_RS10790 7-carboxy-7-deazaguanine synthase QueE 0.66 ABZR86_RS15200 acetate--CoA ligase low > 74
Rhodanobacter sp. FW510-T8 0.16 OKGIIK_01890 7-carboxy-7-deazaguanine synthase 0.64 OKGIIK_15190 acs acetate--CoA ligase low > 52
Acidovorax sp. GW101-3H11 0.16 Ac3H11_3825 Queuosine Biosynthesis QueE Radical SAM 0.46 Ac3H11_951 Acetyl-coenzyme A synthetase (EC 6.2.1.1) — —
Variovorax sp. OAS795 0.16 ABID97_RS07425 7-carboxy-7-deazaguanine synthase 0.47 ABID97_RS27430 acetate--CoA ligase — —
Sphingomonas koreensis DSMZ 15582 0.16 Ga0059261_3210 Organic radical activating enzymes 0.63 Ga0059261_1313 acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 68
Pseudomonas putida KT2440 0.16 PP_1225 7-carboxy-7-deazaguanine synthase 0.71 PP_4487 acetyl-CoA synthetase low > 96
Pseudomonas fluorescens GW456-L13 0.16 PfGW456L13_1861 Queuosine Biosynthesis QueE Radical SAM 0.71 PfGW456L13_1963 Acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 87
Pseudomonas stutzeri RCH2 0.15 Psest_1505 Organic radical activating enzymes 0.66 Psest_2657 acetate--CoA ligase low > 67
Hydrogenophaga sp. GW460-11-11-14-LB1 0.15 GFF4633 Queuosine Biosynthesis QueE Radical SAM 0.46 GFF4107 Acetyl-coenzyme A synthetase (EC 6.2.1.1) low > 90
Pseudomonas syringae pv. syringae B728a ΔmexB 0.15 Psyr_1418 Radical SAM 0.71 Psyr_3572 acetyl-coenzyme A synthetase — —
Pseudomonas syringae pv. syringae B728a 0.15 Psyr_1418 Radical SAM 0.71 Psyr_3572 acetyl-coenzyme A synthetase low > 86
Marinobacter adhaerens HP15 0.15 HP15_3815 organic radical activating enzyme 0.72 HP15_811 acetyl-CoA synthetase low > 73

Not shown: 2 genomes with orthologs for HER17_RS04200 only; 18 genomes with orthologs for HER17_RS17630 only