Conservation of cofitness between GFF4099 and GFF1326 in Hydrogenophaga sp. GW460-11-11-14-LB1

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF4099 Fumarate hydratase class I, aerobic (EC 4.2.1.2) 1.0 GFF1326 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.63 15
Acidovorax sp. GW101-3H11 0.92 Ac3H11_941 Fumarate hydratase class I, aerobic (EC 4.2.1.2) 0.88 Ac3H11_4711 Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
Variovorax sp. OAS795 0.91 ABID97_RS17550 fumarate hydratase 0.87 ABID97_RS23220 glutamate synthase subunit beta low > 91
Variovorax sp. SCN45 0.91 GFF483 Fumarate hydratase class I, aerobic (EC 4.2.1.2) 0.86 GFF5333 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) low > 127
Herbaspirillum seropedicae SmR1 0.82 HSERO_RS07760 fumarate hydratase 0.73 HSERO_RS19590 dihydropyrimidine dehydrogenase subunit A
Cupriavidus basilensis FW507-4G11 0.78 RR42_RS13905 fumarate hydratase 0.74 RR42_RS18985 glutamate synthase low > 128
Ralstonia solanacearum PSI07 0.78 RPSI07_RS14865 fumarate hydratase 0.72 RPSI07_RS10325 glutamate synthase subunit beta low > 81
Paraburkholderia bryophila 376MFSha3.1 0.77 H281DRAFT_04956 fumarase, class I, homodimeric 0.75 H281DRAFT_05621 glutamate synthase (NADH) small subunit
Burkholderia phytofirmans PsJN 0.77 BPHYT_RS06985 fumarate hydratase 0.75 BPHYT_RS17850 dihydropyrimidine dehydrogenase subunit A
Paraburkholderia graminis OAS925 0.77 ABIE53_001662 fumarate hydratase class I 0.75 ABIE53_003732 glutamate synthase (NADPH/NADH) small chain
Ralstonia solanacearum GMI1000 0.77 RS_RS09830 fumarate hydratase 0.71 RS_RS14855 glutamate synthase subunit beta low > 80
Ralstonia sp. UNC404CL21Col 0.77 ABZR87_RS14375 fumarate hydratase 0.75 ABZR87_RS02565 glutamate synthase subunit beta low > 80
Ralstonia solanacearum IBSBF1503 0.76 RALBFv3_RS02460 fumarate hydratase 0.72 RALBFv3_RS06910 glutamate synthase subunit beta low > 76
Ralstonia solanacearum UW163 0.76 UW163_RS11265 fumarate hydratase 0.72 UW163_RS06705 glutamate synthase subunit beta
Paraburkholderia sabiae LMG 24235 0.76 QEN71_RS23780 fumarate hydratase 0.76 QEN71_RS28005 glutamate synthase subunit beta low > 153
Dyella japonica UNC79MFTsu3.2 0.75 ABZR86_RS19555 fumarate hydratase 0.25 ABZR86_RS16800 FAD-dependent oxidoreductase low > 74
Rhodanobacter denitrificans MT42 0.73 LRK55_RS12360 fumarate hydratase 0.27 LRK55_RS10670 FAD-dependent oxidoreductase low > 63
Rhodanobacter sp. FW510-T8 0.73 OKGIIK_02115 ttdA fumarate hydratase 0.68 OKGIIK_15205 Glutamate synthase low > 52
Lysobacter sp. OAE881 0.73 ABIE51_RS12620 fumarate hydratase 0.26 ABIE51_RS01315 FAD-dependent oxidoreductase low > 62
Castellaniella sp019104865 MT123 0.73 ABCV34_RS09450 fumarate hydratase 0.64 ABCV34_RS11155 glutamate synthase subunit beta low > 48
Rhodanobacter denitrificans FW104-10B01 0.73 LRK54_RS12620 fumarate hydratase 0.27 LRK54_RS10965 FAD-dependent oxidoreductase low > 59
Xanthomonas campestris pv. campestris strain 8004 0.72 Xcc-8004.3506.1 Fumarate hydratase class I, aerobic (EC 4.2.1.2) 0.25 Xcc-8004.43.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
Dechlorosoma suillum PS 0.72 Dsui_2001 hydro-lyase, Fe-S type, tartrate/fumarate subfamily,hydro-lyase family enzyme, Fe-S type, tartrate/fumarate subfamily 0.70 Dsui_1097 NADH/NADPH-dependent glutamate synthase small subunit
Pseudomonas simiae WCS417 0.72 PS417_22635 fumarate hydratase 0.24 PS417_02005 glutamate synthase
Pseudomonas syringae pv. syringae B728a 0.71 Psyr_4031 fumarase 0.25 Psyr_0412 glutamate synthase (NADPH) small subunit
Pseudomonas fluorescens SBW25 0.71 PFLU_RS24270 fumarate hydratase 0.24 PFLU_RS02050 NAD(P)-binding protein
Pseudomonas syringae pv. syringae B728a ΔmexB 0.71 Psyr_4031 fumarase 0.25 Psyr_0412 glutamate synthase (NADPH) small subunit
Pseudomonas fluorescens SBW25-INTG 0.71 PFLU_RS24270 fumarate hydratase 0.24 PFLU_RS02050 NAD(P)-binding protein
Pseudomonas fluorescens GW456-L13 0.71 PfGW456L13_1808 Fumarate hydratase class I, aerobic (EC 4.2.1.2) 0.25 PfGW456L13_271 Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
Pseudomonas fluorescens FW300-N1B4 0.71 Pf1N1B4_683 Fumarate hydratase class I, aerobic (EC 4.2.1.2) 0.25 Pf1N1B4_1533 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) low > 87
Pseudomonas fluorescens FW300-N2E3 0.71 AO353_03795 fumarate hydratase 0.25 AO353_12520 glutamate synthase low > 101
Pseudomonas fluorescens FW300-N2E2 0.71 Pf6N2E2_5489 Fumarate hydratase class I, aerobic (EC 4.2.1.2) 0.25 Pf6N2E2_3751 Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
Pseudomonas sp. RS175 0.71 PFR28_03458 Fumarate hydratase class I, aerobic 0.25 PFR28_05016 Glutamate synthase [NADPH] small chain
Pseudomonas fluorescens FW300-N2C3 0.71 AO356_17810 fumarate hydratase 0.25 AO356_09370 glutamate synthase
Pseudomonas stutzeri RCH2 0.71 Psest_3193 hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region 0.25 Psest_3710 glutamate synthase small subunit family protein, proteobacterial
Pseudomonas putida KT2440 0.71 PP_0897 Fumarate hydratase, class I 0.25 PP_5075 glutamate synthase (NADPH) beta subunit
Pseudomonas sp. S08-1 0.70 OH686_18780 Fumarate hydratase class I, aerobic 0.25 OH686_10000 Glutamate synthase [NADPH] small chain
Acinetobacter radioresistens SK82 0.68 MPMX26_00411 Fumarate hydratase class I, aerobic 0.25 MPMX26_02807 Glutamate synthase [NADPH] small chain low > 36
Shewanella loihica PV-4 0.67 Shew_1904 tartrate/fumarate subfamily Fe-S type hydro-lyase alpha subunit (RefSeq) 0.25 Shew_1031 gltD glutamate synthase subunit beta (RefSeq)
Marinobacter adhaerens HP15 0.67 HP15_1143 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit 0.24 HP15_483 oxidoreductase Fe-S binding subunit
Sphingomonas koreensis DSMZ 15582 0.67 Ga0059261_3334 hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region 0.24 Ga0059261_1797 glutamate synthase small subunit family protein, proteobacterial low > 68
Shewanella amazonensis SB2B 0.66 Sama_1688 fumarate hydratase, class I, anaerobic, putative (RefSeq) 0.27 Sama_0856 gltD glutamate synthase subunit beta (RefSeq)
Shewanella oneidensis MR-1 0.66 SO2222 fumarate hydratase, class I, anaerobic, putative (NCBI ptt file) 0.26 SO1324 gltD glutamate synthase, small subunit (NCBI ptt file)
Alteromonas macleodii MIT1002 0.65 MIT1002_02009 Fumarate hydratase class I, anaerobic 0.25 MIT1002_03140 Glutamate synthase [NADPH] small chain
Shewanella sp. ANA-3 0.65 Shewana3_2302 fumarase (RefSeq) 0.26 Shewana3_3051 gltD glutamate synthase subunit beta (RefSeq)
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_06585 fumarate hydratase 0.50 CSW01_12025 glutamate synthase subunit beta low > 62
Dinoroseobacter shibae DFL-12 0.55 Dshi_1426 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit (RefSeq) 0.23 Dshi_0001 glutamate synthase, small subunit (RefSeq) low > 64
Rhodopseudomonas palustris CGA009 0.21 TX73_020085 fumarate hydratase 0.58 TX73_004595 glutamate synthase subunit beta
Escherichia coli BL21 0.20 ECD_01581 fumarate hydratase (fumarase A), aerobic Class I 0.25 ECD_03078 glutamate synthase, 4Fe-4S protein, small subunit low > 60
Magnetospirillum magneticum AMB-1 0.20 AMB_RS06760 fumarate hydratase 0.59 AMB_RS11780 glutamate synthase subunit beta
Escherichia coli ECOR27 0.20 NOLOHH_18150 fumB class I fumarate hydratase 0.25 NOLOHH_09680 gltD glutamate synthase subunit GltD low > 57
Escherichia coli ECRC101 0.20 OKFHMN_12525 fumB class I fumarate hydratase 0.25 OKFHMN_17880 gltD glutamate synthase subunit GltD
Escherichia coli ECRC102 0.20 NIAGMN_10370 fumB class I fumarate hydratase 0.25 NIAGMN_15640 gltD glutamate synthase subunit GltD
Escherichia coli ECOR38 0.20 HEPCGN_06020 fumB class I fumarate hydratase 0.25 HEPCGN_16755 gltD glutamate synthase subunit GltD low > 85
Enterobacter sp. TBS_079 0.20 MPMX20_02021 Fumarate hydratase class I, aerobic 0.25 MPMX20_04127 Glutamate synthase [NADPH] small chain low > 85
Escherichia fergusonii Becca 0.20 EFB2_02380 Fumarate hydratase class I, aerobic 0.25 EFB2_00610 Glutamate synthase [NADPH] small chain low > 86
Escherichia coli ECRC62 0.20 BNILDI_16940 fumB class I fumarate hydratase 0.25 BNILDI_01855 gltD glutamate synthase subunit GltD
Escherichia coli Nissle 1917 0.20 ECOLIN_RS09000 class I fumarate hydratase 0.26 ECOLIN_RS18480 glutamate synthase subunit GltD low > 52
Escherichia coli BW25113 0.20 b1612 fumA fumarate hydratase (fumarase A), aerobic Class I (NCBI) 0.25 b3213 gltD glutamate synthase, 4Fe-4S protein, small subunit (NCBI) low > 76
Escherichia coli ECRC101 0.20 MCAODC_03035 fumB class I fumarate hydratase 0.25 MCAODC_08400 gltD glutamate synthase subunit GltD
Rhizobium sp. OAE497 0.20 ABIE40_RS10550 fumarate hydratase 0.52 ABIE40_RS16270 glutamate synthase subunit beta
Escherichia coli ECRC99 0.20 KEDOAH_15640 fumB class I fumarate hydratase 0.25 KEDOAH_10270 gltD glutamate synthase subunit GltD
Escherichia coli ECRC98 0.20 JDDGAC_16160 fumB class I fumarate hydratase 0.25 JDDGAC_21505 gltD glutamate synthase subunit GltD
Escherichia coli HS(pFamp)R (ATCC 700891) 0.20 OHPLBJKB_03922 Fumarate hydratase class I, anaerobic 0.25 OHPLBJKB_00487 Glutamate synthase [NADPH] small chain low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.19 GFF1477 Fumarate hydratase class I, anaerobic (EC 4.2.1.2) 0.25 GFF2957 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) low > 78
Rhodospirillum rubrum S1H 0.19 Rru_A2206 tartrate dehydrogenase (NCBI) 0.23 Rru_A0018 Glutamate synthase, NADH/NADPH, small subunit 2 (NCBI)
Klebsiella michiganensis M5al 0.19 BWI76_RS08450 fumarate hydratase 0.25 BWI76_RS25320 glutamate synthase low > 92
Serratia liquefaciens MT49 0.19 IAI46_21370 fumarate hydratase 0.25 IAI46_22350 glutamate synthase small subunit low > 86
Bacteroides thetaiotaomicron VPI-5482 0.19 BT2256 fumarate hydratase class I, anaerobic (NCBI ptt file) 0.39 BT0552 glutamate synthase, small subunit (NCBI ptt file)
Parabacteroides merdae CL09T00C40 0.19 HMPREF1078_RS17710 fumarate hydratase 0.42 HMPREF1078_RS01265 glutamate synthase subunit beta
Rahnella sp. WP5 0.19 EX31_RS01160 fumarate hydratase 0.24 EX31_RS12510 FAD-dependent oxidoreductase low > 89
Bacteroides stercoris CC31F 0.19 HMPREF1181_RS09470 fumarate hydratase 0.37 HMPREF1181_RS16050 glutamate synthase subunit beta
Bacteroides ovatus ATCC 8483 0.19 BACOVA_03087 hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 0.39 BACOVA_03757 pyridine nucleotide-disulfide oxidoreductase
Erwinia tracheiphila SCR3 0.19 LU632_RS01205 class I fumarate hydratase FumA 0.25 LU632_RS21320 glutamate synthase small subunit low > 74
Phocaeicola vulgatus CL09T03C04 0.19 HMPREF1058_RS13805 fumarate hydratase 0.37 HMPREF1058_RS06925 glutamate synthase subunit beta
Azospirillum sp. SherDot2 0.19 MPMX19_03166 Fumarate hydratase class I, aerobic 0.24 MPMX19_02658 Glutamate synthase [NADPH] small chain
Dickeya dadantii 3937 0.19 DDA3937_RS04540 fumarate hydratase 0.25 DDA3937_RS01660 FAD-dependent oxidoreductase low > 74
Dickeya dianthicola ME23 0.19 DZA65_RS04420 fumarate hydratase 0.25 DZA65_RS01630 FAD-dependent oxidoreductase low > 75
Pectobacterium carotovorum WPP14 0.18 HER17_RS17120 fumarate hydratase 0.24 HER17_RS19915 glutamate synthase small subunit low > 75
Dickeya dianthicola 67-19 0.18 HGI48_RS04500 fumarate hydratase 0.24 HGI48_RS01555 glutamate synthase small subunit low > 71
Bosea sp. OAE506 0.18 ABIE41_RS00110 fumarate hydratase 0.48 ABIE41_RS08570 glutamate synthase subunit beta

Not shown: 4 genomes with orthologs for GFF4099 only; 14 genomes with orthologs for GFF1326 only