Conservation of cofitness between PS417_14035 and PS417_06330 in Pseudomonas simiae WCS417

82 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas simiae WCS417 1.0 PS417_14035 lactoylglutathione lyase 1.0 PS417_06330 S-(hydroxymethyl)glutathione dehydrogenase 0.39 4
Pseudomonas fluorescens SBW25-INTG 0.99 PFLU_RS14580 lactoylglutathione lyase 1.00 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.99 PFLU_RS14580 lactoylglutathione lyase 1.00 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 109
Pseudomonas fluorescens FW300-N1B4 0.96 Pf1N1B4_5009 Lactoylglutathione lyase (EC 4.4.1.5) 0.98 Pf1N1B4_3108 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) — —
Pseudomonas fluorescens FW300-N2E3 0.96 AO353_26955 lactoylglutathione lyase 0.98 AO353_16580 S-(hydroxymethyl)glutathione dehydrogenase 0.47 6
Pseudomonas fluorescens GW456-L13 0.96 PfGW456L13_2929 Lactoylglutathione lyase (EC 4.4.1.5) 0.97 PfGW456L13_4682 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 87
Pseudomonas fluorescens FW300-N2C3 0.95 AO356_22815 lactoylglutathione lyase 0.97 AO356_05920 S-(hydroxymethyl)glutathione dehydrogenase 0.30 7
Pseudomonas fluorescens FW300-N2E2 0.94 Pf6N2E2_449 Lactoylglutathione lyase (EC 4.4.1.5) 0.97 Pf6N2E2_3044 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 103
Pseudomonas sp. RS175 0.93 PFR28_02480 Lactoylglutathione lyase 0.95 PFR28_00420 S-(hydroxymethyl)glutathione dehydrogenase low > 88
Pseudomonas syringae pv. syringae B728a ΔmexB 0.86 Psyr_2973 Glyoxalase I 0.96 Psyr_1367 Zinc-containing alcohol dehydrogenase superfamily low > 86
Pseudomonas syringae pv. syringae B728a 0.86 Psyr_2973 Glyoxalase I 0.96 Psyr_1367 Zinc-containing alcohol dehydrogenase superfamily low > 86
Pseudomonas putida KT2440 0.83 PP_3766 Lactoylglutathione lyase 0.97 PP_1616 formaldehyde dehydrogenase, glutathione-dependent low > 96
Variovorax sp. SCN45 0.72 GFF7483 Lactoylglutathione lyase (EC 4.4.1.5) 0.65 GFF2941 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) — —
Lysobacter sp. OAE881 0.71 ABIE51_RS04905 lactoylglutathione lyase 0.75 ABIE51_RS18925 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 62
Serratia liquefaciens MT49 0.66 IAI46_13865 lactoylglutathione lyase 0.84 IAI46_07885 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 86
Xanthomonas campestris pv. campestris strain 8004 0.66 Xcc-8004.4545.1 Lactoylglutathione lyase (EC 4.4.1.5) 0.83 Xcc-8004.982.1 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 74
Marinobacter adhaerens HP15 0.55 HP15_2890 lactoylglutathione lyase 0.85 HP15_4017 formaldehyde dehydrogenase (glutathione-dependent) low > 73
Alteromonas macleodii MIT1002 0.48 MIT1002_02929 Lactoylglutathione lyase 0.80 MIT1002_03089 S-(hydroxymethyl)glutathione dehydrogenase low > 70
Acinetobacter radioresistens SK82 0.26 MPMX26_01061 Lactoylglutathione lyase 0.80 MPMX26_01472 S-(hydroxymethyl)glutathione dehydrogenase low > 36
Pseudomonas stutzeri RCH2 0.26 Psest_3120 lactoylglutathione lyase 0.85 Psest_2816 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 67
Hydrogenophaga sp. GW460-11-11-14-LB1 0.25 GFF3511 Lactoylglutathione lyase (EC 4.4.1.5) 0.65 GFF3318 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 90
Variovorax sp. OAS795 0.25 ABID97_RS21275 lactoylglutathione lyase 0.65 ABID97_RS10235 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 91
Dickeya dadantii 3937 0.25 DDA3937_RS12600 lactoylglutathione lyase 0.81 DDA3937_RS09325 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.50 10
Azospirillum sp. SherDot2 0.25 MPMX19_01003 Lactoylglutathione lyase 0.82 MPMX19_05326 S-(hydroxymethyl)glutathione dehydrogenase low > 112
Synechococcus elongatus PCC 7942 0.25 Synpcc7942_0638 gloA Glyoxalase I 0.79 Synpcc7942_0459 glutathione-dependent formaldehyde dehydrogenase low > 38
Azospirillum brasilense Sp245 0.24 AZOBR_RS07390 glyoxalase I 0.86 AZOBR_RS16515 S-(hydroxymethyl)glutathione dehydrogenase low > 97
Pseudomonas sp. S08-1 0.24 OH686_03925 lactoylglutathione lyase 0.85 OH686_18150 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Acidovorax sp. GW101-3H11 0.24 Ac3H11_2251 Lactoylglutathione lyase (EC 4.4.1.5) 0.75 Ac3H11_3163 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 79
Dickeya dianthicola 67-19 0.24 HGI48_RS12660 lactoylglutathione lyase 0.80 HGI48_RS09350 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 71
Dickeya dianthicola ME23 0.24 DZA65_RS13115 lactoylglutathione lyase 0.80 DZA65_RS09655 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 75
Pantoea sp. MT58 0.24 IAI47_10770 lactoylglutathione lyase 0.83 IAI47_06705 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Herbaspirillum seropedicae SmR1 0.24 HSERO_RS03550 glyoxalase I 0.64 HSERO_RS13615 alcohol dehydrogenase low > 78
Paraburkholderia bryophila 376MFSha3.1 0.24 H281DRAFT_04643 methylmalonyl-CoA epimerase 0.65 H281DRAFT_04166 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase low > 103
Paraburkholderia graminis OAS925 0.24 ABIE53_000803 lactoylglutathione lyase 0.65 ABIE53_003402 S-(hydroxymethyl)glutathione dehydrogenase/alcohol dehydrogenase low > 113
Pectobacterium carotovorum WPP14 0.24 HER17_RS09260 lactoylglutathione lyase 0.84 HER17_RS12790 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 75
Cupriavidus basilensis FW507-4G11 0.24 RR42_RS02800 glyoxalase I 0.65 RR42_RS25775 alcohol dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.24 OKGIIK_17075 gloA lactoylglutathione lyase 0.79 OKGIIK_16185 frmA S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 52
Kangiella aquimarina DSM 16071 0.24 B158DRAFT_1242 lactoylglutathione lyase 0.83 B158DRAFT_0940 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 40
Ralstonia solanacearum GMI1000 0.23 RS_RS02590 lactoylglutathione lyase 0.65 RS_RS03030 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Erwinia tracheiphila SCR3 0.23 LU632_RS11225 gloA lactoylglutathione lyase 0.84 LU632_RS17270 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 74
Paraburkholderia sabiae LMG 24235 0.23 QEN71_RS02140 lactoylglutathione lyase 0.65 QEN71_RS02555 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 153
Shewanella oneidensis MR-1 0.23 SO2044 gloA lactoylglutathione lyase (NCBI ptt file) 0.83 SO2054 adhC alcohol dehydrogenase class III (NCBI ptt file) low > 76
Ralstonia solanacearum PSI07 0.23 RPSI07_RS21450 lactoylglutathione lyase 0.66 RPSI07_RS20965 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 81
Ralstonia solanacearum IBSBF1503 0.23 RALBFv3_RS11765 lactoylglutathione lyase 0.66 RALBFv3_RS12345 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Shewanella sp. ANA-3 0.23 Shewana3_2232 lactoylglutathione lyase (RefSeq) 0.83 Shewana3_1837 alcohol dehydrogenase (RefSeq) — —
Ralstonia solanacearum UW163 0.23 UW163_RS01820 lactoylglutathione lyase 0.66 UW163_RS01260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.23 GFF3623 Lactoylglutathione lyase (EC 4.4.1.5) 0.76 GFF2617 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 78
Castellaniella sp019104865 MT123 0.22 ABCV34_RS09485 lactoylglutathione lyase 0.72 ABCV34_RS09045 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 48
Burkholderia phytofirmans PsJN 0.22 BPHYT_RS03320 lactoylglutathione lyase 0.76 BPHYT_RS00510 S-(hydroxymethyl)glutathione dehydrogenase low > 109
Escherichia coli ECRC62 0.22 BNILDI_16740 Lactoylglutathione lyase 0.73 BNILDI_23065 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.22 OHPLBJKB_02074 Lactoylglutathione lyase 0.73 OHPLBJKB_03314 S-(hydroxymethyl)glutathione dehydrogenase low > 73
Escherichia coli ECRC99 0.22 KEDOAH_00680 Lactoylglutathione lyase 0.73 KEDOAH_19230 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli BW25113 0.22 b1651 gloA glyoxalase I, Ni-dependent (NCBI) 0.73 b0356 frmA alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase (NCBI) low > 76
Escherichia coli ECRC98 0.22 JDDGAC_02020 Lactoylglutathione lyase 0.73 JDDGAC_12395 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Rhodanobacter denitrificans MT42 0.22 LRK55_RS06330 VOC family protein 0.78 LRK55_RS09575 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 63
Escherichia coli ECOR27 0.22 NOLOHH_17950 Lactoylglutathione lyase 0.73 NOLOHH_01650 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli ECOR38 0.22 HEPCGN_05815 Lactoylglutathione lyase 0.73 HEPCGN_07365 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 85
Escherichia coli BL21 0.22 ECD_01621 glyoxalase I, Ni-dependent 0.73 ECD_00310 alcohol dehydrogenase class III; glutathione-dependent formaldehyde dehydrogenase low > 60
Rhodanobacter denitrificans FW104-10B01 0.22 LRK54_RS06585 VOC family protein 0.77 LRK54_RS09935 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 59
Escherichia coli ECRC101 0.22 MCAODC_17980 Lactoylglutathione lyase 0.73 MCAODC_27970 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli ECRC101 0.22 OKFHMN_27430 Lactoylglutathione lyase 0.73 OKFHMN_08740 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli ECRC102 0.22 NIAGMN_00635 Lactoylglutathione lyase 0.73 NIAGMN_06795 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Enterobacter asburiae PDN3 0.22 EX28DRAFT_1649 lactoylglutathione lyase 0.79 EX28DRAFT_1257 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Escherichia coli Nissle 1917 0.22 ECOLIN_RS09205 lactoylglutathione lyase 0.73 ECOLIN_RS02210 S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia fergusonii Becca 0.22 EFB2_02341 Lactoylglutathione lyase 0.73 EFB2_03694 S-(hydroxymethyl)glutathione dehydrogenase low > 86
Enterobacter sp. TBS_079 0.22 MPMX20_01985 Lactoylglutathione lyase 0.80 MPMX20_02209 S-(hydroxymethyl)glutathione dehydrogenase low > 85
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS07720 lactoylglutathione lyase 0.65 ABZR87_RS08285 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Klebsiella michiganensis M5al 0.22 BWI76_RS16480 lactoylglutathione lyase 0.80 BWI76_RS13260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 92
Shewanella amazonensis SB2B 0.21 Sama_1837 lactoylglutathione lyase (RefSeq) 0.82 Sama_0004 alcohol dehydrogenase, zinc-binding (RefSeq) low > 62
Rhodospirillum rubrum S1H 0.21 Rru_A2466 Glyoxalase/bleomycin resistance protein/dioxygenase (NCBI) 0.82 Rru_A3405 Formaldehyde dehydrogenase (glutathione) (NCBI) low > 58
Rhizobium sp. OAE497 0.21 ABIE40_RS08735 lactoylglutathione lyase 0.61 ABIE40_RS09860 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 107
Shewanella loihica PV-4 0.21 Shew_2073 lactoylglutathione lyase (RefSeq) 0.82 Shew_1540 alcohol dehydrogenase (RefSeq) low > 60
Brevundimonas sp. GW460-12-10-14-LB2 0.20 A4249_RS13830 VOC family protein 0.65 A4249_RS00420 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 48
Bosea sp. OAE506 0.19 ABIE41_RS21410 VOC family protein 0.65 ABIE41_RS09635 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 77
Rahnella sp. WP5 0.19 EX31_RS13810 lactoylglutathione lyase 0.83 EX31_RS18715 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 89
Dinoroseobacter shibae DFL-12 0.19 Dshi_0767 Glyoxalase/bleomycin resistance protein/dioxygenase (RefSeq) 0.64 Dshi_0103 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase (RefSeq) low > 64
Agrobacterium fabrum C58 0.19 Atu1802 lactoylglutathione lyase 0.60 Atu1670 alcohol dehydrogenase class III low > 89
Caulobacter crescentus NA1000 0.18 CCNA_01375 lactoylglutathione lyase 0.66 CCNA_02601 glutathione-dependent formaldehyde dehydrogenase low > 66
Caulobacter crescentus NA1000 Δfur 0.18 CCNA_01375 lactoylglutathione lyase 0.66 CCNA_02601 glutathione-dependent formaldehyde dehydrogenase low > 67
Phaeobacter inhibens DSM 17395 0.18 PGA1_c21210 putative lactoylglutathione lyase 0.62 PGA1_c02510 S-(hydroxymethyl)glutathione dehydrogenase FrmA low > 62
Sinorhizobium meliloti 1021 0.18 SMc00290 lactoylglutathione lyase 0.61 SMc01270 alcohol dehydrogenase — —
Sphingomonas koreensis DSMZ 15582 0.17 Ga0059261_2761 Lactoylglutathione lyase and related lyases 0.67 Ga0059261_1819 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 68
Dyella japonica UNC79MFTsu3.2 0.16 ABZR86_RS17390 VOC family protein 0.81 ABZR86_RS17285 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 74

Not shown: 3 genomes with orthologs for PS417_14035 only; 2 genomes with orthologs for PS417_06330 only