Conservation of cofitness between CSW01_04065 and CSW01_11565 in Vibrio cholerae E7946 ATCC 55056

91 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_04065 D-amino acid dehydrogenase small subunit 1.0 CSW01_11565 transcriptional regulator NrdR 0.43 19
Agrobacterium fabrum C58 0.58 Atu3293 D-amino acid dehydrogenase small subunit 0.45 Atu1166 hypothetical protein — —
Acinetobacter baumannii LAC-4 0.58 RR41_RS18375 D-amino acid dehydrogenase 0.61 RR41_RS17860 transcriptional regulator NrdR low > 55
Acinetobacter radioresistens SK82 0.57 MPMX26_01248 D-amino acid dehydrogenase 0.60 MPMX26_00151 Transcriptional repressor NrdR low > 36
Pseudomonas lactucae CFBP13502 0.57 GEMAOFIL_00008 D-amino acid dehydrogenase 1 0.71 GEMAOFIL_05159 Transcriptional repressor NrdR low > 93
Pantoea sp. MT58 0.57 IAI47_08890 D-amino acid dehydrogenase 0.81 IAI47_14775 transcriptional regulator NrdR low > 76
Pantoea agglomerans CFBP13505 P0401 0.57 PagCFBP13505_RS02725 D-amino acid dehydrogenase 0.81 PagCFBP13505_RS10420 transcriptional regulator NrdR — —
Azospirillum sp. SherDot2 0.57 MPMX19_06097 D-amino acid dehydrogenase 1 0.49 MPMX19_00728 Transcriptional repressor NrdR low > 112
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_2144 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) 0.72 Pf1N1B4_2648 Ribonucleotide reductase transcriptional regulator NrdR — —
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_09155 amino acid dehydrogenase 0.73 AO353_06720 NrdR family transcriptional regulator low > 101
Rhodanobacter denitrificans FW104-10B01 0.57 LRK54_RS00590 D-amino acid dehydrogenase 0.61 LRK54_RS04615 transcriptional regulator NrdR low > 59
Azospirillum brasilense Sp245 0.57 AZOBR_RS08020 D-alanine dehydrogenase (EC 1.4.99.-) (from data) 0.49 AZOBR_RS10020 NrdR family transcriptional regulator — —
Erwinia amylovora T8 0.57 OLJFJH_13160 D-amino acid dehydrogenase 0.79 OLJFJH_18095 transcriptional regulator NrdR low > 58
Rhodanobacter denitrificans MT42 0.57 LRK55_RS00360 D-amino acid dehydrogenase 0.61 LRK55_RS04390 transcriptional regulator NrdR low > 63
Pseudomonas stutzeri RCH2 0.57 Psest_3793 D-alanine dehydrogenase (EC 1.4.99.-) (from data) 0.74 Psest_3553 transcriptional regulator NrdR — —
Rhodanobacter sp000427505 FW510-R12 0.57 LRK53_RS09560 D-amino acid dehydrogenase 0.62 LRK53_RS05395 transcriptional regulator NrdR low > 59
Rhodanobacter sp. FW510-T8 0.57 OKGIIK_06665 dadA D-amino acid dehydrogenase small subunit 0.62 OKGIIK_11435 nrdR transcriptional regulator NrdR low > 52
Pseudomonas sp. S08-1 0.57 OH686_13685 D-amino acid dehydrogenase 0.75 OH686_15690 transcriptional regulator NrdR low > 80
Pseudomonas fluorescens SBW25 0.57 PFLU_RS29380 D-amino acid dehydrogenase 0.71 PFLU_RS26905 transcriptional regulator NrdR low > 109
Pseudomonas simiae WCS417 0.57 PS417_27705 amino acid dehydrogenase 0.72 PS417_25270 NrdR family transcriptional regulator low > 88
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS29380 D-amino acid dehydrogenase 0.71 PFLU_RS26905 transcriptional regulator NrdR low > 109
Pseudomonas fluorescens GW456-L13 0.56 PfGW456L13_812 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) 0.72 PfGW456L13_1312 Ribonucleotide reductase transcriptional regulator NrdR low > 87
Pseudomonas sp. SVBP6 0.56 COO64_RS01395 dadA D-amino acid dehydrogenase 0.72 COO64_RS15895 nrdR transcriptional regulator NrdR low > 93
Xanthomonas campestris pv. campestris strain 8004 0.56 Xcc-8004.4621.1 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) 0.58 Xcc-8004.4397.1 Ribonucleotide reductase transcriptional regulator NrdR — —
Xanthobacter sp. DMC5 0.56 GFF1413 D-amino acid dehydrogenase 1 0.42 GFF576 Transcriptional repressor NrdR — —
Erwinia tracheiphila SCR3 0.56 LU632_RS13070 D-amino acid dehydrogenase 0.76 LU632_RS18590 nrdR transcriptional regulator NrdR low > 74
Serratia liquefaciens MT49 0.56 IAI46_14460 D-amino acid dehydrogenase 0.79 IAI46_04890 transcriptional regulator NrdR low > 86
Herbaspirillum seropedicae SmR1 0.56 HSERO_RS08375 D-amino acid dehydrogenase small subunit 0.59 HSERO_RS06145 NrdR family transcriptional regulator low > 78
Pseudomonas sp. DMC3 0.56 GFF390 D-amino acid dehydrogenase 1 0.72 GFF3826 Transcriptional repressor NrdR low > 89
Pseudomonas aeruginosa PA14 0.56 IKLFDK_26930 D-amino acid dehydrogenase 0.72 IKLFDK_20915 transcriptional regulator NrdR low > 100
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_12620 amino acid dehydrogenase 0.72 AO356_14925 NrdR family transcriptional regulator — —
Rahnella sp. WP5 0.56 EX31_RS10485 D-amino acid dehydrogenase 0.80 EX31_RS22120 transcriptional regulator NrdR low > 89
Variovorax sp. OAS795 0.56 ABID97_RS18125 D-amino acid dehydrogenase 0.49 ABID97_RS17895 transcriptional regulator NrdR low > 91
Pseudomonas putida KT2440 0.56 PP_4434 D-amino acid dehydrogenase 1 small subunit 0.72 PP_0513 DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP low > 96
Erwinia tracheiphila HP pepo 2.2 0.56 IJEDHG_22535 D-amino acid dehydrogenase 0.76 IJEDHG_25990 nrdR transcriptional regulator NrdR low > 61
Klebsiella michiganensis M5al 0.56 BWI76_RS17735 D-amino acid dehydrogenase small subunit 0.79 BWI76_RS06345 transcriptional regulator NrdR — —
Pectobacterium carotovorum WPP14 0.56 HER17_RS11170 D-amino acid dehydrogenase 0.79 HER17_RS15965 transcriptional regulator NrdR low > 75
Enterobacter asburiae PDN3 0.55 EX28DRAFT_0766 Glycine/D-amino acid oxidases (deaminating) 0.80 EX28DRAFT_2557 transcriptional regulator NrdR — —
Pseudomonas syringae pv. syringae B728a 0.55 Psyr_0235 D-amino acid dehydrogenase small subunit 0.72 Psyr_4463 Protein of unknown function DUF193 low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.55 Psyr_0235 D-amino acid dehydrogenase small subunit 0.72 Psyr_4463 Protein of unknown function DUF193 low > 86
Escherichia coli Nissle 1917 0.55 ECOLIN_RS07185 D-amino acid dehydrogenase 0.81 ECOLIN_RS02500 transcriptional regulator NrdR low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.55 OHPLBJKB_02500 D-amino acid dehydrogenase 0.81 OHPLBJKB_03263 Transcriptional repressor NrdR low > 74
Escherichia coli ECRC99 0.55 KEDOAH_25305 dadA D-amino acid dehydrogenase 0.81 KEDOAH_19505 nrdR transcriptional regulator NrdR — —
Escherichia coli ECRC62 0.55 BNILDI_18890 dadA D-amino acid dehydrogenase 0.81 BNILDI_22820 nrdR transcriptional regulator NrdR — —
Escherichia coli ECRC98 0.55 JDDGAC_06220 dadA D-amino acid dehydrogenase 0.81 JDDGAC_12115 nrdR transcriptional regulator NrdR — —
Escherichia coli BW25113 0.55 b1189 dadA D-amino acid dehydrogenase (quinone) DadA (EC 1.4.5.1) (from data) 0.81 b0413 ybaD hypothetical protein (NCBI) — —
Escherichia fergusonii Becca 0.55 EFB2_02743 D-amino acid dehydrogenase 0.81 EFB2_03644 Transcriptional repressor NrdR low > 86
Escherichia coli BL21 0.55 ECD_01164 D-amino acid dehydrogenase 0.81 ECD_00361 Nrd regulon repressor low > 61
Escherichia coli ECRC102 0.55 NIAGMN_27930 dadA D-amino acid dehydrogenase 0.81 NIAGMN_06515 nrdR transcriptional regulator NrdR low > 80
Escherichia coli ECOR27 0.55 NOLOHH_20725 dadA D-amino acid dehydrogenase 0.81 NOLOHH_01405 nrdR transcriptional regulator NrdR low > 76
Escherichia coli ECRC101 0.55 MCAODC_21880 dadA D-amino acid dehydrogenase 0.81 MCAODC_27685 nrdR transcriptional regulator NrdR low > 88
Escherichia coli ECRC100 0.55 OKFHMN_28290 dadA D-amino acid dehydrogenase 0.81 OKFHMN_08460 nrdR transcriptional regulator NrdR — —
Escherichia coli ECOR38 0.55 HEPCGN_24750 dadA D-amino acid dehydrogenase 0.81 HEPCGN_07085 nrdR transcriptional regulator NrdR low > 88
Pseudomonas sp. BP01 0.55 JOY50_RS09125 dadA D-amino acid dehydrogenase 0.72 JOY50_RS20130 nrdR transcriptional regulator NrdR low > 84
Pseudomonas segetis P6 0.55 MPMX49_00008 D-amino acid dehydrogenase 1 0.72 MPMX49_00989 Transcriptional repressor NrdR low > 75
Klebsiella pneumoniae MKP103 0.55 KDGMDA_25050 D-amino acid dehydrogenase 0.78 KDGMDA_14435 transcriptional regulator NrdR low > 95
Dickeya dianthicola 67-19 0.55 HGI48_RS11195 D-amino acid dehydrogenase 0.79 HGI48_RS05560 transcriptional regulator NrdR low > 71
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF2804 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) 0.69 GFF4317 Ribonucleotide reductase transcriptional regulator NrdR low > 78
Enterobacter sp. TBS_079 0.55 MPMX20_02699 D-amino acid dehydrogenase 0.80 MPMX20_01005 Transcriptional repressor NrdR low > 85
Dickeya dianthicola ME23 0.54 DZA65_RS11540 D-amino acid dehydrogenase 0.79 DZA65_RS05885 transcriptional regulator NrdR low > 75
Brevundimonas sp. GW460-12-10-14-LB2 0.54 A4249_RS08770 D-amino acid dehydrogenase 0.46 A4249_RS06035 transcriptional regulator NrdR — —
Paraburkholderia graminis OAS925 0.54 ABIE53_003133 D-amino-acid dehydrogenase 0.51 ABIE53_000889 transcriptional repressor NrdR low > 113
Methylophilus sp. DMC18 0.54 GFF2173 D-amino acid dehydrogenase 1 0.55 GFF73 Transcriptional repressor NrdR low > 43
Variovorax sp. SCN45 0.54 GFF1773 D-amino acid dehydrogenase (EC 1.4.99.6) 0.49 GFF561 Ribonucleotide reductase transcriptional regulator NrdR low > 127
Ralstonia solanacearum UW163 0.54 UW163_RS15940 D-amino acid dehydrogenase small subunit 0.52 UW163_RS00675 transcriptional regulator NrdR — —
Ralstonia solanacearum IBSBF1503 0.54 RALBFv3_RS13870 D-amino acid dehydrogenase small subunit 0.52 RALBFv3_RS12890 transcriptional regulator NrdR low > 76
Dickeya dadantii 3937 0.54 DDA3937_RS11170 D-amino acid dehydrogenase 0.79 DDA3937_RS05500 transcriptional regulator NrdR low > 74
Ralstonia solanacearum GMI1000 0.54 RS_RS04605 D-amino acid dehydrogenase small subunit 0.52 RS_RS03665 transcriptional regulator NrdR low > 80
Paraburkholderia bryophila 376MFSha3.1 0.54 H281DRAFT_04287 D-amino-acid dehydrogenase 0.51 H281DRAFT_04727 transcriptional repressor NrdR low > 103
Ralstonia solanacearum PSI07 0.54 RPSI07_RS19600 D-amino acid dehydrogenase small subunit 0.52 RPSI07_RS20335 transcriptional regulator NrdR low > 81
Burkholderia phytofirmans PsJN 0.53 BPHYT_RS14790 D-amino acid dehydrogenase 0.51 BPHYT_RS03730 transcriptional repressor NrdR low > 109
Paraburkholderia sabiae LMG 24235 0.53 QEN71_RS04190 D-amino acid dehydrogenase 0.51 QEN71_RS26230 transcriptional regulator NrdR low > 153
Ralstonia sp. UNC404CL21Col 0.53 ABZR87_RS09560 D-amino acid dehydrogenase 0.52 ABZR87_RS08950 transcriptional regulator NrdR low > 80
Castellaniella sp019104865 MT123 0.52 ABCV34_RS10810 D-amino acid dehydrogenase 0.47 ABCV34_RS10550 transcriptional regulator NrdR low > 48
Cupriavidus basilensis FW507-4G11 0.52 RR42_RS04585 amino acid dehydrogenase 0.54 RR42_RS15490 NrdR family transcriptional regulator low > 128
Dinoroseobacter shibae DFL-12 0.50 Dshi_0558 D-amino-acid dehydrogenase (RefSeq) 0.43 Dshi_2257 ATP-cone domain protein (RefSeq) — —
Dechlorosoma suillum PS 0.42 Dsui_0501 glycine/D-amino acid oxidase, deaminating 0.51 Dsui_1266 transcriptional regulator NrdR — —
Magnetospirillum magneticum AMB-1 0.41 AMB_RS14080 D-amino-acid dehydrogenase 0.49 AMB_RS10475 transcriptional regulator NrdR — —
Rhodospirillum rubrum S1H 0.40 Rru_A1546 FAD dependent oxidoreductase (NCBI) 0.46 Rru_A1826 Protein of unknown function DUF193 (NCBI) — —
Marinobacter adhaerens HP15 0.38 HP15_2610 D-amino acid dehydrogenase small subunit 0.71 HP15_491 transcriptional repressor NrdR low > 73
Hydrogenophaga sp. GW460-11-11-14-LB1 0.37 GFF1973 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) 0.47 GFF5153 Ribonucleotide reductase transcriptional regulator NrdR low > 90
Acidovorax sp. GW101-3H11 0.33 Ac3H11_4848 D-alanine dehydrogenase (EC 1.4.99.-) (from data) 0.44 Ac3H11_2922 Ribonucleotide reductase transcriptional regulator NrdR — —
Sphingomonas koreensis DSMZ 15582 0.25 Ga0059261_3351 Glycine/D-amino acid oxidases (deaminating) 0.45 Ga0059261_1985 transcriptional regulator NrdR low > 68
Dyella japonica UNC79MFTsu3.2 0.18 ABZR86_RS08930 FAD-dependent oxidoreductase 0.63 ABZR86_RS10710 transcriptional regulator NrdR — —
Shewanella amazonensis SB2B 0.17 Sama_1533 D-amino-acid dehydrogenase (RefSeq) 0.75 Sama_1015 nrdR transcriptional regulator NrdR (RefSeq) low > 62
Rhodopseudomonas palustris CGA009 0.16 TX73_019540 FAD-dependent oxidoreductase 0.45 TX73_014120 transcriptional regulator NrdR — —
Sinorhizobium meliloti 1021 0.16 SM_b20267 D-amino acid dehydrogenase 0.45 SMc01771 transcriptional regulator NrdR — —
Shewanella loihica PV-4 0.16 Shew_2360 D-hydroxyproline dehydrogenase (from data) 0.79 Shew_1186 transcriptional regulator NrdR (RefSeq) low > 60
Phaeobacter inhibens DSM 17395 0.15 PGA1_c05140 D-amino acid dehydrogenase small subunit 0.42 PGA1_c08860 transcriptional repressor — —
Rhizobium sp. OAE497 0.14 ABIE40_RS02050 FAD-dependent oxidoreductase 0.43 ABIE40_RS06720 transcriptional regulator NrdR low > 107
Bosea sp. OAE506 0.14 ABIE41_RS13645 FAD-binding oxidoreductase 0.42 ABIE41_RS19765 transcriptional regulator NrdR — —
Sphingobium sp. HT1-2 0.08 GFF1197 hypothetical protein 0.42 GFF3899 Ribonucleotide reductase transcriptional regulator NrdR — —

Not shown: 4 genomes with orthologs for CSW01_04065 only; 12 genomes with orthologs for CSW01_11565 only