Conservation of cofitness between CSW01_00335 and CSW01_10730 in Vibrio cholerae E7946 ATCC 55056

94 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_00335 phosphomethylpyrimidine synthase 1.0 CSW01_10730 ArsC family reductase 0.57 3
Pectobacterium carotovorum WPP14 0.76 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.40 HER17_RS15305 ArsC family reductase low > 75
Rahnella sp. WP5 0.76 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.38 EX31_RS22800 ArsC family reductase low > 89
Klebsiella pneumoniae MKP103 0.75 KDGMDA_10040 phosphomethylpyrimidine synthase ThiC 0.41 KDGMDA_27705 ArsC family reductase low > 95
Dickeya dianthicola ME23 0.75 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.42 DZA65_RS06505 ArsC family reductase low > 75
Dickeya dadantii 3937 0.75 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.41 DDA3937_RS06110 ArsC family reductase 0.67 68
Erwinia amylovora T8 0.75 OLJFJH_06740 phosphomethylpyrimidine synthase ThiC 0.44 OLJFJH_10730 ArsC family reductase low > 58
Erwinia tracheiphila SCR3 0.75 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.37 LU632_RS08360 ArsC family reductase low > 73
Pantoea sp. MT58 0.75 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.40 IAI47_05305 ArsC family reductase low > 76
Escherichia coli ECOR27 0.75 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.45 NOLOHH_13640 arsC ArsC family reductase low > 76
Serratia liquefaciens MT49 0.75 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.45 IAI46_18735 ArsC family reductase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.75 GFF4198 Thiamin biosynthesis protein ThiC 0.45 GFF2187 FIG138056: a glutathione-dependent thiol reductase — —
Enterobacter sp. TBS_079 0.75 MPMX20_00217 Phosphomethylpyrimidine synthase 0.42 MPMX20_03332 Protein YffB low > 85
Escherichia coli BW25113 0.74 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.44 b2471 yffB hypothetical protein (NCBI) low > 76
Pantoea agglomerans CFBP13505 P0401 0.74 PagCFBP13505_RS22620 phosphomethylpyrimidine synthase ThiC 0.40 PagCFBP13505_RS19850 ArsC family reductase low > 74
Escherichia coli ECRC62 0.74 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.45 BNILDI_12450 arsC ArsC family reductase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.74 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.45 OHPLBJKB_01260 Protein YffB low > 74
Klebsiella michiganensis M5al 0.74 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.42 BWI76_RS20865 arsenate reductase low > 92
Escherichia coli ECRC102 0.74 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.45 NIAGMN_19730 yffB ArsC family reductase low > 80
Escherichia coli Nissle 1917 0.74 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.43 ECOLIN_RS14100 ArsC family reductase — —
Escherichia coli ECRC99 0.74 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.44 KEDOAH_06260 arsC ArsC family reductase — —
Escherichia coli ECRC98 0.74 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.45 JDDGAC_25905 yffB ArsC family reductase low > 87
Escherichia coli ECRC101 0.74 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.45 MCAODC_12490 yffB ArsC family reductase low > 87
Escherichia coli ECRC100 0.74 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.45 OKFHMN_21960 yffB ArsC family reductase low > 79
Escherichia coli BL21 0.74 ECD_03871 phosphomethylpyrimidine synthase 0.44 ECD_02362 putative ArsC family reductase — —
Dickeya dianthicola 67-19 0.74 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.41 HGI48_RS06155 ArsC family reductase low > 71
Enterobacter asburiae PDN3 0.74 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.43 EX28DRAFT_0190 transcriptional regulator, Spx/MgsR family low > 76
Escherichia coli ECOR38 0.74 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.44 HEPCGN_21130 arsC ArsC family reductase low > 88
Escherichia fergusonii Becca 0.74 EFB2_04617 Phosphomethylpyrimidine synthase 0.44 EFB2_01417 Protein YffB low > 86
Shewanella loihica PV-4 0.74 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.45 Shew_1863 arsenate reductase and related (RefSeq) — —
Alteromonas macleodii MIT1002 0.74 MIT1002_00097 Phosphomethylpyrimidine synthase 0.52 MIT1002_01546 Regulatory protein spx low > 70
Shewanella amazonensis SB2B 0.72 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.44 Sama_1648 hypothetical protein (RefSeq) — —
Shewanella oneidensis MR-1 0.71 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.44 SO2470 conserved hypothetical protein (NCBI ptt file) low > 76
Pseudomonas aeruginosa MRSN321 0.71 DY961_RS10660 thiC;go_function=iron-sulfur phosphomethylpyrimidine synthase ThiC 0.42 DY961_RS14655 ArsC family reductase low > 100
Pseudomonas aeruginosa PUPa3 0.71 DQ20_RS51400 thiC;go_function=iron-sulfur phosphomethylpyrimidine synthase ThiC 0.42 DQ20_RS42470 ArsC family reductase low > 101
Pseudomonas aeruginosa PA14 0.71 IKLFDK_28675 phosphomethylpyrimidine synthase ThiC 0.43 IKLFDK_18710 ArsC family reductase low > 98
Shewanella sp. ANA-3 0.71 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.44 Shewana3_1913 arsenate reductase and related (RefSeq) — —
Pseudomonas sp. S08-1 0.70 OH686_15885 phosphomethylpyrimidine synthase 0.45 OH686_06505 a glutathione-dependent thiol reductase low > 80
Pseudomonas putida KT2440 0.70 PP_4922 Phosphomethylpyrimidine synthase 0.44 PP_1531 putative glutathione-dependent thiol reductase — —
Pseudomonas sp. DMC3 0.70 GFF3183 Phosphomethylpyrimidine synthase 0.44 GFF2048 Protein YffB — —
Marinobacter adhaerens HP15 0.70 HP15_453 thiamine biosynthesis protein thiC 0.44 HP15_1161 arsenate reductase low > 73
Pseudomonas sp. BP01 0.69 JOY50_RS10065 thiC phosphomethylpyrimidine synthase ThiC 0.43 JOY50_RS26165 ArsC family reductase low > 84
Pseudomonas sp. RS175 0.69 PFR28_05091 Phosphomethylpyrimidine synthase 0.43 PFR28_00391 hypothetical protein low > 88
Pseudomonas fluorescens FW300-N2C3 0.69 AO356_08810 thiamine biosynthesis protein ThiC 0.42 AO356_06065 ArsC family transcriptional regulator low > 104
Pseudomonas sp. SVBP6 0.69 COO64_RS17755 thiC phosphomethylpyrimidine synthase ThiC 0.41 COO64_RS19615 ArsC family reductase low > 93
Pseudomonas stutzeri RCH2 0.69 Psest_0477 thiamine biosynthesis protein ThiC 0.41 Psest_1466 transcriptional regulator, Spx/MgsR family low > 67
Pseudomonas fluorescens GW456-L13 0.69 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.44 PfGW456L13_4715 FIG138056: a glutathione-dependent thiol reductase low > 87
Methylophilus sp. DMC18 0.69 GFF2191 Phosphomethylpyrimidine synthase 0.39 GFF896 Protein YffB low > 43
Dechlorosoma suillum PS 0.69 Dsui_0422 thiamine biosynthesis protein ThiC 0.40 Dsui_2545 transcriptional regulator, Spx/MgsR family — —
Pseudomonas fluorescens FW300-N1B4 0.69 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.43 Pf1N1B4_3078 FIG138056: a glutathione-dependent thiol reductase low > 87
Pseudomonas fluorescens FW300-N2E2 0.69 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.42 Pf6N2E2_3077 FIG138056: a glutathione-dependent thiol reductase low > 103
Pseudomonas simiae WCS417 0.69 PS417_02355 thiamine biosynthesis protein ThiC 0.44 PS417_06185 ArsC family transcriptional regulator — —
Pseudomonas lactucae CFBP13502 0.69 GEMAOFIL_00708 Phosphomethylpyrimidine synthase 0.44 GEMAOFIL_01407 Protein YffB low > 96
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_0544 hydroxymethylpyrimidine synthase 0.44 Psyr_1337 Conserved hypothetical protein ArsC related protein low > 86
Mucilaginibacter yixingensis YX-36 DSM 26809 0.69 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.36 ABZR88_RS16335 Spx/MgsR family RNA polymerase-binding regulatory protein — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_0544 hydroxymethylpyrimidine synthase 0.44 Psyr_1337 Conserved hypothetical protein ArsC related protein low > 86
Pseudomonas fluorescens FW300-N2E3 0.69 AO353_13010 thiamine biosynthesis protein ThiC 0.42 AO353_16440 ArsC family transcriptional regulator low > 101
Pseudomonas fluorescens SBW25 0.69 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.44 PFLU_RS06250 ArsC family reductase low > 109
Pseudomonas fluorescens SBW25-INTG 0.69 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.44 PFLU_RS06250 ArsC family reductase low > 109
Pseudomonas segetis P6 0.68 MPMX49_04184 Phosphomethylpyrimidine synthase 0.43 MPMX49_03466 Protein YffB low > 75
Acinetobacter baumannii LAC-4 0.68 RR41_RS17715 phosphomethylpyrimidine synthase ThiC 0.36 RR41_RS00790 arsenate reductase low > 55
Pedobacter sp. GW460-11-11-14-LB5 0.68 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.40 CA265_RS17115 arsenate reductase low > 88
Lysobacter sp. OAE881 0.68 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.34 ABIE51_RS06990 Spx/MgsR family RNA polymerase-binding regulatory protein low > 62
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.43 HSERO_RS10795 arsenate reductase — —
Paraburkholderia bryophila 376MFSha3.1 0.68 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.41 H281DRAFT_00598 arsenate reductase — —
Paraburkholderia graminis OAS925 0.68 ABIE53_002857 phosphomethylpyrimidine synthase 0.41 ABIE53_002518 arsenate reductase — —
Burkholderia phytofirmans PsJN 0.67 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.41 BPHYT_RS12195 arsenate reductase — —
Dyella japonica UNC79MFTsu3.2 0.67 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.36 ABZR86_RS21560 Spx/MgsR family RNA polymerase-binding regulatory protein low > 74
Paraburkholderia sabiae LMG 24235 0.67 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.42 QEN71_RS06360 ArsC family reductase low > 153
Rhodanobacter sp. FW510-T8 0.67 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.34 OKGIIK_03130 Arsenate reductase low > 53
Xanthomonas campestris pv. campestris strain 8004 0.66 Xcc-8004.1066.1 hypothetical protein 0.33 Xcc-8004.3540.1 FIG138056: a glutathione-dependent thiol reductase — —
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.44 ABZR87_RS11755 arsenate reductase low > 80
Ralstonia solanacearum UW163 0.65 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.42 UW163_RS13635 ArsC family reductase — —
Ralstonia solanacearum GMI1000 0.65 RS_RS00555 phosphomethylpyrimidine synthase 0.38 RS_RS06975 ArsC family reductase — —
Cupriavidus basilensis FW507-4G11 0.65 RR42_RS01290 thiamine biosynthesis protein ThiC 0.43 RR42_RS11945 ArsC family transcriptional regulator — —
Ralstonia solanacearum IBSBF1503 0.65 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.42 RALBFv3_RS00305 ArsC family reductase — —
Ralstonia solanacearum PSI07 0.65 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.43 RPSI07_RS17170 arsenate reductase low > 81
Kangiella aquimarina DSM 16071 0.65 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.38 B158DRAFT_1070 transcriptional regulator, Spx/MgsR family low > 40
Variovorax sp. SCN45 0.64 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.35 GFF3093 FIG138056: a glutathione-dependent thiol reductase low > 127
Variovorax sp. OAS795 0.63 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.37 ABID97_RS21655 ArsC family reductase low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.63 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.34 GFF296 FIG138056: a glutathione-dependent thiol reductase — —
Caulobacter crescentus NA1000 Δfur 0.62 CCNA_02109 thiamine biosynthesis protein thiC 0.43 CCNA_01714 Spx/MgsR-related protein low > 67
Caulobacter crescentus NA1000 0.62 CCNA_02109 thiamine biosynthesis protein thiC 0.43 CCNA_01714 Spx/MgsR-related protein low > 66
Agrobacterium fabrum C58 0.61 Atu2569 thiamine biosynthesis protein 0.47 Atu0276 hypothetical protein low > 89
Dinoroseobacter shibae DFL-12 0.61 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.21 Dshi_0770 arsenate reductase and related (RefSeq) — —
Sinorhizobium meliloti 1021 0.61 SM_b20615 thiamine biosynthesis protein ThiC 0.50 SMc00386 hypothetical protein low > 103
Phaeobacter inhibens DSM 17395 0.61 PGA1_c09110 thiamine biosynthesis protein ThiC 0.26 PGA1_c21050 glutaredoxin-like protein low > 62
Brevundimonas sp. GW460-12-10-14-LB2 0.61 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.45 A4249_RS03665 ArsC family reductase low > 48
Acidovorax sp. GW101-3H11 0.61 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.38 Ac3H11_2613 FIG138056: a glutathione-dependent thiol reductase low > 79
Xanthobacter sp. DMC5 0.61 GFF257 Phosphomethylpyrimidine synthase 0.47 GFF1300 Protein YffB — —
Sphingomonas koreensis DSMZ 15582 0.59 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.44 Ga0059261_0315 transcriptional regulator, Spx/MgsR family low > 68
Sphingobium sp. HT1-2 0.59 GFF941 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.41 GFF670 FIG138056: a glutathione-dependent thiol reductase low > 95
Rhodopseudomonas palustris CGA009 0.59 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.43 TX73_011755 ArsC family reductase low > 86
Rhodanobacter sp000427505 FW510-R12 0.58 LRK53_RS03795 phosphomethylpyrimidine synthase ThiC 0.33 LRK53_RS14350 Spx/MgsR family RNA polymerase-binding regulatory protein low > 59
Bosea sp. OAE506 0.58 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.45 ABIE41_RS18295 ArsC family reductase low > 77

Not shown: 17 genomes with orthologs for CSW01_00335 only; 4 genomes with orthologs for CSW01_10730 only