Conservation of cofitness between BWI76_RS04665 and BWI76_RS00845 in Klebsiella michiganensis M5al

82 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 1.0 BWI76_RS00845 N-acetyl-gamma-glutamyl-phosphate reductase 0.93 19
Enterobacter sp. TBS_079 0.93 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.93 MPMX20_04522 N-acetyl-gamma-glutamyl-phosphate reductase 0.85 35
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.91 GFF2344 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 78
Enterobacter asburiae PDN3 0.92 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.93 EX28DRAFT_4420 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) 0.61 54
Escherichia coli BL21 0.88 ECD_00073 3-isopropylmalate dehydratase small subunit 0.89 ECD_03843 N-acetyl-gamma-glutamylphosphate reductase, NAD(P)-binding 0.84 31
Escherichia coli BW25113 0.88 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 0.89 b3958 argC N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) 0.90 40
Escherichia coli ECOR27 0.88 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 0.89 NOLOHH_05730 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.96 3
Escherichia coli ECRC62 0.88 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 0.89 BNILDI_05795 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.91 45
Escherichia coli HS(pFamp)R (ATCC 700891) 0.88 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit 0.89 OHPLBJKB_04092 N-acetyl-gamma-glutamyl-phosphate reductase low > 73
Escherichia fergusonii Becca 0.88 EFB2_03974 3-isopropylmalate dehydratase small subunit 0.88 EFB2_04656 N-acetyl-gamma-glutamyl-phosphate reductase low > 86
Escherichia coli ECOR38 0.88 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 0.88 HEPCGN_12230 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.91 21
Escherichia coli Nissle 1917 0.88 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit 0.88 ECOLIN_RS22845 N-acetyl-gamma-glutamyl-phosphate reductase 0.75 27
Escherichia coli ECRC99 0.87 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit 0.88 KEDOAH_14575 argC N-acetyl-gamma-glutamyl-phosphate reductase
Escherichia coli ECRC102 0.87 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit 0.88 NIAGMN_11335 argC N-acetyl-gamma-glutamyl-phosphate reductase
Escherichia coli ECRC100 0.87 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 0.88 OKFHMN_13585 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.93 35
Escherichia coli ECRC98 0.87 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 0.88 JDDGAC_17210 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.78 55
Escherichia coli ECRC101 0.87 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 0.88 MCAODC_04085 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.91 29
Serratia liquefaciens MT49 0.84 IAI46_03340 3-isopropylmalate dehydratase small subunit 0.84 IAI46_24515 N-acetyl-gamma-glutamyl-phosphate reductase low > 86
Rahnella sp. WP5 0.84 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.80 EX31_RS14190 N-acetyl-gamma-glutamyl-phosphate reductase 0.97 9
Dickeya dianthicola ME23 0.84 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.80 DZA65_RS00935 N-acetyl-gamma-glutamyl-phosphate reductase 0.77 23
Dickeya dadantii 3937 0.84 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.80 DDA3937_RS20350 N-acetyl-gamma-glutamyl-phosphate reductase 0.61 72
Pectobacterium carotovorum WPP14 0.84 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.80 HER17_RS20630 N-acetyl-gamma-glutamyl-phosphate reductase low > 75
Dickeya dianthicola 67-19 0.83 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.81 HGI48_RS00875 N-acetyl-gamma-glutamyl-phosphate reductase 0.73 33
Pantoea sp. MT58 0.83 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.80 IAI47_00905 N-acetyl-gamma-glutamyl-phosphate reductase 0.78 65
Erwinia tracheiphila SCR3 0.74 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.78 LU632_RS19615 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.76 25
Vibrio cholerae E7946 ATCC 55056 0.73 CSW01_12610 3-isopropylmalate dehydratase small subunit 0.67 CSW01_13380 N-acetyl-gamma-glutamyl-phosphate reductase low > 62
Pseudomonas stutzeri RCH2 0.63 Psest_2590 3-isopropylmalate dehydratase, small subunit 0.31 Psest_3639 N-acetyl-gamma-glutamyl-phosphate reductase, common form
Shewanella loihica PV-4 0.63 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.45 Shew_0202 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.97 14
Pseudomonas sp. S08-1 0.62 OH686_04475 3-isopropylmalate dehydratase small subunit 0.34 OH686_15195 N-acetyl-gamma-glutamyl-phosphate reductase 0.59 54
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_14 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.34 Pf1N1B4_2559 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38)
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3947 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.33 PfGW456L13_1233 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) 0.84 44
Pseudomonas sp. RS175 0.62 PFR28_02823 3-isopropylmalate dehydratase small subunit 1 0.33 PFR28_04033 N-acetyl-gamma-glutamyl-phosphate reductase low > 88
Alteromonas macleodii MIT1002 0.62 MIT1002_00946 3-isopropylmalate dehydratase small subunit 1 0.48 MIT1002_00471 N-acetyl-gamma-glutamyl-phosphate reductase 0.97 10
Pseudomonas putida KT2440 0.62 PP_1986 3-isopropylmalate dehydratase small subunit 0.34 PP_0432 N-acetyl-gamma-glutamyl-phosphate reductase 1 low > 96
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_64 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.33 Pf6N2E2_4836 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 103
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_20625 3-isopropylmalate dehydratase 0.33 AO353_07155 N-acetyl-gamma-glutamyl-phosphate reductase 0.65 57
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.34 PFLU_RS27315 N-acetyl-gamma-glutamyl-phosphate reductase
Pseudomonas fluorescens SBW25 0.61 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.34 PFLU_RS27315 N-acetyl-gamma-glutamyl-phosphate reductase
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_21405 3-isopropylmalate dehydratase 0.34 AO356_14490 N-acetyl-gamma-glutamyl-phosphate reductase low > 104
Xanthomonas campestris pv. campestris strain 8004 0.61 Xcc-8004.1050.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.18 Xcc-8004.2322.1 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) 0.77 30
Pseudomonas syringae pv. syringae B728a ΔmexB 0.61 Psyr_1984 3-isopropylmalate dehydratase, small subunit 0.32 Psyr_4569 N-acetyl-gamma-glutamyl-phosphate reductase
Pseudomonas syringae pv. syringae B728a 0.61 Psyr_1984 3-isopropylmalate dehydratase, small subunit 0.32 Psyr_4569 N-acetyl-gamma-glutamyl-phosphate reductase
Pseudomonas simiae WCS417 0.61 PS417_18595 3-isopropylmalate dehydratase 0.33 PS417_25660 N-acetyl-gamma-glutamyl-phosphate reductase
Shewanella amazonensis SB2B 0.60 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) 0.46 Sama_0256 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.94 22
Shewanella oneidensis MR-1 0.60 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.46 SO0275 argC N-acetyl-gamma-glutamyl-phosphate reductase (NCBI ptt file) 0.95 29
Variovorax sp. SCN45 0.60 GFF3889 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.13 GFF4146 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 127
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS14390 3-isopropylmalate dehydratase 0.14 RR42_RS01210 n-acetyl-gamma-glutamyl-phosphate reductase low > 128
Shewanella sp. ANA-3 0.59 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.46 Shewana3_3905 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.89 44
Ralstonia solanacearum PSI07 0.59 RPSI07_RS14700 3-isopropylmalate dehydratase small subunit 0.15 RPSI07_RS23280 N-acetyl-gamma-glutamyl-phosphate reductase
Kangiella aquimarina DSM 16071 0.59 B158DRAFT_1320 3-isopropylmalate dehydratase, small subunit 0.18 B158DRAFT_1979 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 40
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS02615 3-isopropylmalate dehydratase small subunit 0.15 RALBFv3_RS10090 N-acetyl-gamma-glutamyl-phosphate reductase low > 76
Ralstonia solanacearum UW163 0.58 UW163_RS11110 3-isopropylmalate dehydratase small subunit 0.15 UW163_RS03490 N-acetyl-gamma-glutamyl-phosphate reductase
Herbaspirillum seropedicae SmR1 0.57 HSERO_RS16505 3-isopropylmalate dehydratase small subunit 0.31 HSERO_RS19210 N-acetyl-gamma-glutamyl-phosphate reductase low > 78
Acidovorax sp. GW101-3H11 0.57 Ac3H11_1527 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.13 Ac3H11_2950 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 79
Marinobacter adhaerens HP15 0.55 HP15_1833 isopropylmalate isomerase small subunit 0.32 HP15_352 N-acetyl-gamma-glutamyl-phosphate reductase 0.89 9
Castellaniella sp019104865 MT123 0.55 ABCV34_RS04285 3-isopropylmalate dehydratase small subunit 0.32 ABCV34_RS10590 N-acetyl-gamma-glutamyl-phosphate reductase
Acinetobacter radioresistens SK82 0.55 MPMX26_00346 3-isopropylmalate dehydratase small subunit 1 0.31 MPMX26_01281 N-acetyl-gamma-glutamyl-phosphate reductase 0.88 33
Azospirillum sp. SherDot2 0.51 MPMX19_00606 3-isopropylmalate dehydratase small subunit 1 0.28 MPMX19_03843 N-acetyl-gamma-glutamyl-phosphate reductase
Magnetospirillum magneticum AMB-1 0.51 AMB_RS20565 3-isopropylmalate dehydratase small subunit 0.30 AMB_RS09075 N-acetyl-gamma-glutamyl-phosphate reductase
Dinoroseobacter shibae DFL-12 0.51 Dshi_0083 3-isopropylmalate dehydratase, small subunit (RefSeq) 0.26 Dshi_1759 N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq)
Rhodospirillum rubrum S1H 0.50 Rru_A1190 3-isopropylmalate dehydratase small subunit region (NCBI) 0.33 Rru_A2421 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) 0.75 13
Azospirillum brasilense Sp245 0.50 AZOBR_RS14135 isopropylmalate isomerase 0.27 AZOBR_RS07795 N-acetyl-gamma-glutamyl-phosphate reductase
Phaeobacter inhibens DSM 17395 0.49 PGA1_c29790 3-isopropylmalate dehydratase small subunit 0.23 PGA1_c17050 N-acetyl-gamma-glutamyl-phosphate reductase ArgC 0.67 56
Bosea sp. OAE506 0.47 ABIE41_RS11640 3-isopropylmalate dehydratase small subunit 0.16 ABIE41_RS15755 N-acetyl-gamma-glutamyl-phosphate reductase
Rhodanobacter denitrificans MT42 0.45 LRK55_RS07100 3-isopropylmalate dehydratase small subunit 0.17 LRK55_RS02140 N-acetyl-gamma-glutamyl-phosphate reductase low > 63
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS07370 3-isopropylmalate dehydratase small subunit 0.17 LRK54_RS02385 N-acetyl-gamma-glutamyl-phosphate reductase low > 59
Mucilaginibacter yixingensis YX-36 DSM 26809 0.45 ABZR88_RS11600 3-isopropylmalate dehydratase small subunit 0.22 ABZR88_RS15505 N-acetyl-gamma-glutamyl-phosphate reductase
Pedobacter sp. GW460-11-11-14-LB5 0.44 CA265_RS15840 3-isopropylmalate dehydratase small subunit 0.21 CA265_RS18540 N-succinylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.87 45
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_09440 3-isopropylmalate dehydratase small subunit 0.19 CA264_06250 N-acetyl-gamma-glutamyl-phosphate reductase low > 74
Bifidobacterium breve UCC2003 0.43 BBR_RS19625 3-isopropylmalate dehydratase small subunit 0.18 BBR_RS13885 N-acetyl-gamma-glutamyl-phosphate reductase low > 34
Bacteroides stercoris CC31F 0.43 HMPREF1181_RS14140 3-isopropylmalate dehydratase small subunit 0.20 HMPREF1181_RS03450 N-acetyl-gamma-glutamyl-phosphate reductase 0.86 25
Phocaeicola dorei CL03T12C01 0.42 ABI39_RS10205 3-isopropylmalate dehydratase small subunit 0.19 ABI39_RS02970 N-acetyl-gamma-glutamyl-phosphate reductase 0.79 24
Lysobacter sp. OAE881 0.42 ABIE51_RS17580 3-isopropylmalate dehydratase small subunit 0.20 ABIE51_RS13385 N-acetyl-gamma-glutamyl-phosphate reductase 0.90 16
Phocaeicola vulgatus CL09T03C04 0.42 HMPREF1058_RS14555 3-isopropylmalate dehydratase small subunit 0.19 HMPREF1058_RS08840 N-acetyl-gamma-glutamyl-phosphate reductase low > 67
Parabacteroides merdae CL09T00C40 0.42 HMPREF1078_RS16655 3-isopropylmalate dehydratase small subunit 0.21 HMPREF1078_RS10580 N-acetyl-gamma-glutamyl-phosphate reductase 0.88 12
Rhodanobacter sp. FW510-T8 0.40 OKGIIK_13590 leuD 3-isopropylmalate dehydratase small subunit 0.18 OKGIIK_09435 argC N-acetyl-gamma-glutamyl-phosphate reductase low > 52
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS15955 3-isopropylmalate dehydratase small subunit 0.19 ABZR86_RS08700 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.87 59
Bacteroides ovatus ATCC 8483 0.39 BACOVA_04602 3-isopropylmalate dehydratase, small subunit 0.21 BACOVA_03589 N-acetyl-gamma-glutamyl-phosphate reductase 0.94 14
Bacteroides thetaiotaomicron VPI-5482 0.39 BT1859 3-isopropylmalate dehydratase small subunit (NCBI ptt file) 0.20 BT3759 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) 0.87 9
Mycobacterium tuberculosis H37Rv 0.39 Rv2987c Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) 0.21 Rv1652 Probable N-acetyl-gamma-glutamyl-phoshate reductase ArgC
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_2060 3-isopropylmalate dehydratase, small subunit 0.20 Echvi_3847 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data)
Sphingomonas koreensis DSMZ 15582 0.37 Ga0059261_4225 3-isopropylmalate dehydratase, small subunit 0.10 Ga0059261_0351 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.97 7
Synechococcus elongatus PCC 7942 0.27 Synpcc7942_2548 leuD isopropylmalate isomerase small subunit 0.28 Synpcc7942_1433 argC N-acetyl-gamma-glutamyl-phosphate reductase

Not shown: 16 genomes with orthologs for BWI76_RS04665 only; 4 genomes with orthologs for BWI76_RS00845 only