Conservation of cofitness between BWI76_RS00805 and BWI76_RS00845 in Klebsiella michiganensis M5al

82 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 1.0 BWI76_RS00845 N-acetyl-gamma-glutamyl-phosphate reductase 0.89 20
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.91 GFF2344 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 78
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.93 EX28DRAFT_4420 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 76
Escherichia coli ECOR27 0.95 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.89 NOLOHH_05730 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.93 43
Escherichia coli BW25113 0.95 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.89 b3958 argC N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) 0.90 46
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase 0.89 OHPLBJKB_04092 N-acetyl-gamma-glutamyl-phosphate reductase low > 73
Escherichia coli BL21 0.95 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.89 ECD_03843 N-acetyl-gamma-glutamylphosphate reductase, NAD(P)-binding 0.89 25
Enterobacter sp. TBS_079 0.95 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.93 MPMX20_04522 N-acetyl-gamma-glutamyl-phosphate reductase 0.69 43
Escherichia coli ECRC62 0.95 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.89 BNILDI_05795 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.97 31
Escherichia coli ECRC100 0.95 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.88 OKFHMN_13585 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.99 7
Escherichia coli ECRC102 0.95 NIAGMN_11420 metF methylenetetrahydrofolate reductase 0.88 NIAGMN_11335 argC N-acetyl-gamma-glutamyl-phosphate reductase
Escherichia coli ECOR38 0.95 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.88 HEPCGN_12230 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.92 39
Escherichia coli ECRC98 0.95 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.88 JDDGAC_17210 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.83 50
Escherichia coli ECRC101 0.95 MCAODC_04165 metF methylenetetrahydrofolate reductase 0.88 MCAODC_04085 argC N-acetyl-gamma-glutamyl-phosphate reductase 0.93 23
Escherichia coli ECRC99 0.95 KEDOAH_14495 metF methylenetetrahydrofolate reductase 0.88 KEDOAH_14575 argC N-acetyl-gamma-glutamyl-phosphate reductase
Escherichia fergusonii Becca 0.94 EFB2_04672 5,10-methylenetetrahydrofolate reductase 0.88 EFB2_04656 N-acetyl-gamma-glutamyl-phosphate reductase low > 86
Escherichia coli Nissle 1917 0.94 ECOLIN_RS22760 methylenetetrahydrofolate reductase 0.88 ECOLIN_RS22845 N-acetyl-gamma-glutamyl-phosphate reductase 0.87 25
Pantoea sp. MT58 0.92 IAI47_00890 methylenetetrahydrofolate reductase 0.80 IAI47_00905 N-acetyl-gamma-glutamyl-phosphate reductase 0.50 31
Serratia liquefaciens MT49 0.92 IAI46_24530 methylenetetrahydrofolate reductase 0.84 IAI46_24515 N-acetyl-gamma-glutamyl-phosphate reductase 0.52 78
Dickeya dadantii 3937 0.91 DDA3937_RS00960 methylenetetrahydrofolate reductase 0.80 DDA3937_RS20350 N-acetyl-gamma-glutamyl-phosphate reductase 0.45 9
Rahnella sp. WP5 0.91 EX31_RS14205 methylenetetrahydrofolate reductase 0.80 EX31_RS14190 N-acetyl-gamma-glutamyl-phosphate reductase 0.92 10
Pectobacterium carotovorum WPP14 0.90 HER17_RS00950 methylenetetrahydrofolate reductase 0.80 HER17_RS20630 N-acetyl-gamma-glutamyl-phosphate reductase low > 75
Dickeya dianthicola 67-19 0.90 HGI48_RS20415 methylenetetrahydrofolate reductase 0.81 HGI48_RS00875 N-acetyl-gamma-glutamyl-phosphate reductase low > 71
Dickeya dianthicola ME23 0.90 DZA65_RS21460 methylenetetrahydrofolate reductase 0.80 DZA65_RS00935 N-acetyl-gamma-glutamyl-phosphate reductase 0.69 32
Erwinia tracheiphila SCR3 0.87 LU632_RS19630 metF methylenetetrahydrofolate reductase 0.78 LU632_RS19615 argC N-acetyl-gamma-glutamyl-phosphate reductase low > 74
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_13560 methylenetetrahydrofolate reductase 0.67 CSW01_13380 N-acetyl-gamma-glutamyl-phosphate reductase low > 62
Shewanella oneidensis MR-1 0.76 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.46 SO0275 argC N-acetyl-gamma-glutamyl-phosphate reductase (NCBI ptt file) 0.93 34
Shewanella amazonensis SB2B 0.76 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.46 Sama_0256 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.97 16
Shewanella sp. ANA-3 0.76 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.46 Shewana3_3905 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.92 38
Shewanella loihica PV-4 0.75 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.45 Shew_0202 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) 0.98 17
Alteromonas macleodii MIT1002 0.70 MIT1002_03670 5,10-methylenetetrahydrofolate reductase 0.48 MIT1002_00471 N-acetyl-gamma-glutamyl-phosphate reductase low > 70
Kangiella aquimarina DSM 16071 0.61 B158DRAFT_2461 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20) 0.18 B158DRAFT_1979 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 40
Azospirillum brasilense Sp245 0.55 AZOBR_RS09540 5 10-methylenetetrahydrofolate reductase 0.27 AZOBR_RS07795 N-acetyl-gamma-glutamyl-phosphate reductase
Magnetospirillum magneticum AMB-1 0.55 AMB_RS02230 methylenetetrahydrofolate reductase 0.30 AMB_RS09075 N-acetyl-gamma-glutamyl-phosphate reductase
Azospirillum sp. SherDot2 0.55 MPMX19_00635 5,10-methylenetetrahydrofolate reductase 0.28 MPMX19_03843 N-acetyl-gamma-glutamyl-phosphate reductase
Sphingomonas koreensis DSMZ 15582 0.54 Ga0059261_0992 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.10 Ga0059261_0351 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.64 41
Bosea sp. OAE506 0.52 ABIE41_RS12475 methylenetetrahydrofolate reductase [NAD(P)H] 0.16 ABIE41_RS15755 N-acetyl-gamma-glutamyl-phosphate reductase low > 77
Rhodospirillum rubrum S1H 0.52 Rru_A1530 5,10-methylenetetrahydrofolate reductase (NCBI) 0.33 Rru_A2421 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) 0.68 43
Phaeobacter inhibens DSM 17395 0.40 PGA1_c11700 5,10-methylenetetrahydrofolate reductase MetF 0.23 PGA1_c17050 N-acetyl-gamma-glutamyl-phosphate reductase ArgC 0.67 59
Cupriavidus basilensis FW507-4G11 0.39 RR42_RS01385 5,10-methylenetetrahydrofolate reductase 0.14 RR42_RS01210 n-acetyl-gamma-glutamyl-phosphate reductase low > 128
Ralstonia solanacearum PSI07 0.38 RPSI07_RS23495 methylenetetrahydrofolate reductase [NAD(P)H] 0.15 RPSI07_RS23280 N-acetyl-gamma-glutamyl-phosphate reductase low > 81
Ralstonia solanacearum UW163 0.38 UW163_RS03705 methylenetetrahydrofolate reductase [NAD(P)H] 0.15 UW163_RS03490 N-acetyl-gamma-glutamyl-phosphate reductase
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS09875 methylenetetrahydrofolate reductase [NAD(P)H] 0.15 RALBFv3_RS10090 N-acetyl-gamma-glutamyl-phosphate reductase low > 76
Pseudomonas sp. RS175 0.38 PFR28_04202 5,10-methylenetetrahydrofolate reductase 0.33 PFR28_04033 N-acetyl-gamma-glutamyl-phosphate reductase low > 88
Dinoroseobacter shibae DFL-12 0.37 Dshi_2080 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.26 Dshi_1759 N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq)
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.4336.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.18 Xcc-8004.2322.1 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) 0.50 68
Pseudomonas simiae WCS417 0.37 PS417_26510 5,10-methylenetetrahydrofolate reductase 0.33 PS417_25660 N-acetyl-gamma-glutamyl-phosphate reductase
Pseudomonas sp. S08-1 0.37 OH686_10820 methylenetetrahydrofolate reductase [NAD(P)H] 0.34 OH686_15195 N-acetyl-gamma-glutamyl-phosphate reductase 0.65 42
Marinobacter adhaerens HP15 0.37 HP15_2917 5,10-methylenetetrahydrofolate reductase-like protein 0.32 HP15_352 N-acetyl-gamma-glutamyl-phosphate reductase 0.92 14
Pseudomonas fluorescens FW300-N1B4 0.37 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.34 Pf1N1B4_2559 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38)
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.34 PFLU_RS27315 N-acetyl-gamma-glutamyl-phosphate reductase
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.34 PFLU_RS27315 N-acetyl-gamma-glutamyl-phosphate reductase
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.33 Pf6N2E2_4836 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 103
Rhodanobacter denitrificans MT42 0.37 LRK55_RS11765 methylenetetrahydrofolate reductase [NAD(P)H] 0.17 LRK55_RS02140 N-acetyl-gamma-glutamyl-phosphate reductase low > 63
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS12030 methylenetetrahydrofolate reductase [NAD(P)H] 0.17 LRK54_RS02385 N-acetyl-gamma-glutamyl-phosphate reductase 0.75 8
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_13605 5,10-methylenetetrahydrofolate reductase 0.34 AO356_14490 N-acetyl-gamma-glutamyl-phosphate reductase low > 104
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08015 5,10-methylenetetrahydrofolate reductase 0.33 AO353_07155 N-acetyl-gamma-glutamyl-phosphate reductase 0.72 43
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS21425 5,10-methylenetetrahydrofolate reductase 0.31 HSERO_RS19210 N-acetyl-gamma-glutamyl-phosphate reductase low > 78
Rhodanobacter sp. FW510-T8 0.36 OKGIIK_11830 metF methylenetetrahydrofolate reductase [NAD(P)H] 0.18 OKGIIK_09435 argC N-acetyl-gamma-glutamyl-phosphate reductase low > 52
Pseudomonas fluorescens GW456-L13 0.36 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.33 PfGW456L13_1233 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) 0.81 48
Pseudomonas putida KT2440 0.36 PP_4977 5,10-methylenetetrahydrofolate reductase 0.34 PP_0432 N-acetyl-gamma-glutamyl-phosphate reductase 1 low > 96
Dyella japonica UNC79MFTsu3.2 0.36 ABZR86_RS11570 methylenetetrahydrofolate reductase [NAD(P)H] 0.19 ABZR86_RS08700 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.92 45
Pseudomonas stutzeri RCH2 0.36 Psest_0313 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.31 Psest_3639 N-acetyl-gamma-glutamyl-phosphate reductase, common form
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.32 Psyr_4569 N-acetyl-gamma-glutamyl-phosphate reductase
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.32 Psyr_4569 N-acetyl-gamma-glutamyl-phosphate reductase
Lysobacter sp. OAE881 0.35 ABIE51_RS16490 methylenetetrahydrofolate reductase [NAD(P)H] 0.20 ABIE51_RS13385 N-acetyl-gamma-glutamyl-phosphate reductase 0.98 9
Castellaniella sp019104865 MT123 0.35 ABCV34_RS13550 methylenetetrahydrofolate reductase [NAD(P)H] 0.32 ABCV34_RS10590 N-acetyl-gamma-glutamyl-phosphate reductase
Acidovorax sp. GW101-3H11 0.34 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.13 Ac3H11_2950 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 79
Variovorax sp. SCN45 0.32 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.13 GFF4146 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) low > 127
Acinetobacter radioresistens SK82 0.32 MPMX26_01002 5,10-methylenetetrahydrofolate reductase 0.31 MPMX26_01281 N-acetyl-gamma-glutamyl-phosphate reductase low > 36
Desulfovibrio vulgaris Hildenborough JW710 0.28 DVU0997 metF 5,10-methylenetetrahydrofolate reductase (TIGR) 0.29 DVU0492 argC N-acetyl-gamma-glutamyl-phosphate reductase (TIGR) 0.83 18
Desulfovibrio vulgaris Miyazaki F 0.27 DvMF_3034 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.30 DvMF_1717 argC N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq)
Bifidobacterium breve UCC2003 0.23 BBR_RS15410 methylenetetrahydrofolate reductase [NAD(P)H] 0.18 BBR_RS13885 N-acetyl-gamma-glutamyl-phosphate reductase low > 34
Mucilaginibacter yixingensis YX-36 DSM 26809 0.22 ABZR88_RS20935 methylenetetrahydrofolate reductase [NAD(P)H] 0.22 ABZR88_RS15505 N-acetyl-gamma-glutamyl-phosphate reductase
Parabacteroides merdae CL09T00C40 0.21 HMPREF1078_RS07860 methylenetetrahydrofolate reductase [NAD(P)H] 0.21 HMPREF1078_RS10580 N-acetyl-gamma-glutamyl-phosphate reductase low > 61
Echinicola vietnamensis KMM 6221, DSM 17526 0.21 Echvi_3637 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.20 Echvi_3847 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) 0.91 24
Pedobacter sp. GW460-11-11-14-LB5 0.21 CA265_RS23445 methylenetetrahydrofolate reductase [NAD(P)H] 0.21 CA265_RS18540 N-succinylglutamylphosphate reductase (EC 1.2.1.38) (from data) 0.91 44
Bacteroides thetaiotaomicron VPI-5482 0.20 BT3821 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.20 BT3759 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) low > 81
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_16780 methylenetetrahydrofolate reductase [NAD(P)H] 0.19 CA264_06250 N-acetyl-gamma-glutamyl-phosphate reductase low > 74
Phocaeicola dorei CL03T12C01 0.19 ABI39_RS15570 methylenetetrahydrofolate reductase [NAD(P)H] 0.19 ABI39_RS02970 N-acetyl-gamma-glutamyl-phosphate reductase low > 72
Phocaeicola vulgatus CL09T03C04 0.19 HMPREF1058_RS01490 methylenetetrahydrofolate reductase [NAD(P)H] 0.19 HMPREF1058_RS08840 N-acetyl-gamma-glutamyl-phosphate reductase low > 67
Bacteroides stercoris CC31F 0.18 HMPREF1181_RS00120 methylenetetrahydrofolate reductase [NAD(P)H] 0.20 HMPREF1181_RS03450 N-acetyl-gamma-glutamyl-phosphate reductase low > 56
Bacteroides ovatus ATCC 8483 0.16 BACOVA_03666 methylenetetrahydrofolate reductase (NAD(P)H) 0.21 BACOVA_03589 N-acetyl-gamma-glutamyl-phosphate reductase low > 94

Not shown: 17 genomes with orthologs for BWI76_RS00805 only; 4 genomes with orthologs for BWI76_RS00845 only