Conservation of cofitness between BBR_RS15810 and BBR_RS16085 in Bifidobacterium breve UCC2003

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bifidobacterium breve UCC2003 1.0 BBR_RS15810 tryptophan synthase subunit alpha 1.0 BBR_RS16085 anthranilate synthase component I 0.71 4
Mycobacterium tuberculosis H37Rv 0.40 Rv1613 Probable tryptophan synthase, alpha subunit TrpA 0.41 Rv1609 Anthranilate synthase component I TrpE (glutamine amidotransferase)
Methanococcus maripaludis S2 0.27 MMP_RS05185 tryptophan synthase subunit alpha 0.23 MMP_RS05205 anthranilate synthase component I
Pseudomonas stutzeri RCH2 0.27 Psest_0062 tryptophan synthase, alpha subunit 0.35 Psest_3650 anthranilate synthase component I, non-proteobacterial lineages 0.80 5
Methanococcus maripaludis JJ 0.26 MMJJ_RS09195 tryptophan synthase subunit alpha 0.23 MMJJ_RS09175 anthranilate synthase component I
Marinobacter adhaerens HP15 0.26 HP15_1826 tryptophan synthase, alpha subunit 0.36 HP15_3288 anthranilate synthase component I
Pseudomonas sp. S08-1 0.26 OH686_12430 tryptophan synthase, alpha subunit 0.35 OH686_15125 anthranilate synthase component I 0.86 4
Synechococcus elongatus PCC 7942 0.26 Synpcc7942_0411 trpA tryptophan synthase subunit alpha 0.29 Synpcc7942_1003 trpE anthranilate synthase, component I
Phaeobacter inhibens DSM 17395 0.26 PGA1_c04930 tryptophan synthase alpha chain 0.26 PGA1_c16860 anthranilate synthase component 1
Magnetospirillum magneticum AMB-1 0.26 AMB_RS20300 tryptophan synthase subunit alpha 0.31 AMB_RS09175 anthranilate synthase component I
Pseudomonas simiae WCS417 0.25 PS417_00180 tryptophan synthase subunit alpha 0.36 PS417_25725 anthranilate synthase component I 0.74 5
Pseudomonas fluorescens SBW25 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.36 PFLU_RS27380 anthranilate synthase component I low > 109
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_10705 tryptophan synthase subunit alpha 0.36 AO353_07230 anthranilate synthase 0.85 5
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.36 PFLU_RS27380 anthranilate synthase component I 0.33 40
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_10910 tryptophan synthase subunit alpha 0.35 AO356_14420 anthranilate synthase 0.96 3
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_565 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.35 PfGW456L13_1217 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.96 4
Pseudomonas sp. RS175 0.25 PFR28_04716 Tryptophan synthase alpha chain 0.35 PFR28_04047 Anthranilate synthase component 1
Dinoroseobacter shibae DFL-12 0.25 Dshi_0952 tryptophan synthase, alpha subunit (RefSeq) 0.28 Dshi_1796 anthranilate synthase component I (RefSeq)
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_1830 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.36 Pf1N1B4_2545 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.91 4
Mucilaginibacter yixingensis YX-36 DSM 26809 0.25 ABZR88_RS10660 tryptophan synthase subunit alpha 0.26 ABZR88_RS16595 anthranilate synthase component I family protein
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4047 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.35 Pf6N2E2_4822 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 103
Acinetobacter radioresistens SK82 0.25 MPMX26_02611 Tryptophan synthase alpha chain 0.33 MPMX26_00199 Anthranilate synthase component 1
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.35 Psyr_4609 anthranilate synthase, component I low > 86
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.35 Psyr_4609 anthranilate synthase, component I 0.65 14
Pseudomonas putida KT2440 0.24 PP_0082 tryptophan synthase alpha chain 0.36 PP_0417 Anthranilate synthase component 1 0.84 10
Acidovorax sp. GW101-3H11 0.24 Ac3H11_1535 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.34 Ac3H11_767 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.98 2
Parabacteroides merdae CL09T00C40 0.23 HMPREF1078_RS00120 tryptophan synthase subunit alpha 0.23 HMPREF1078_RS00145 anthranilate synthase component I family protein 0.99 1
Variovorax sp. SCN45 0.23 GFF3882 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.33 GFF5896 Anthranilate synthase, aminase component (EC 4.1.3.27)
Dechlorosoma suillum PS 0.23 Dsui_3191 tryptophan synthase, alpha subunit 0.37 Dsui_0219 anthranilate synthase component I
Phocaeicola dorei CL03T12C01 0.23 ABI39_RS21075 tryptophan synthase subunit alpha 0.24 ABI39_RS21050 anthranilate synthase component I family protein 0.75 32
Phocaeicola vulgatus CL09T03C04 0.23 HMPREF1058_RS07200 tryptophan synthase subunit alpha 0.24 HMPREF1058_RS07175 anthranilate synthase component I family protein 0.95 5
Bosea sp. OAE506 0.23 ABIE41_RS03930 tryptophan synthase subunit alpha 0.29 ABIE41_RS15730 anthranilate synthase component I
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS15350 tryptophan synthase subunit alpha 0.23 HMPREF1181_RS15325 anthranilate synthase component I family protein 0.95 5
Serratia liquefaciens MT49 0.22 IAI46_14045 tryptophan synthase subunit alpha 0.22 IAI46_14020 anthranilate synthase component 1 0.75 8
Bacteroides thetaiotaomicron VPI-5482 0.22 BT0527 tryptophan synthase alpha chain (NCBI ptt file) 0.23 BT0532 anthranilate synthase component I (NCBI ptt file) 0.67 55
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS14350 tryptophan synthase alpha chain 0.34 RR42_RS18295 anthranilate synthase component I
Azospirillum brasilense Sp245 0.22 AZOBR_RS00520 tryptophan synthase subunit alpha 0.29 AZOBR_RS07490 anthranilate synthase subunit I low > 97
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS14490 tryptophan synthase subunit alpha 0.34 ABZR87_RS02140 anthranilate synthase component I 0.91 5
Vibrio cholerae E7946 ATCC 55056 0.22 CSW01_05925 tryptophan synthase subunit alpha 0.22 CSW01_05950 anthranilate synthase component I 0.79 29
Bacteroides ovatus ATCC 8483 0.22 BACOVA_03785 tryptophan synthase, alpha subunit 0.23 BACOVA_03780 chorismate binding enzyme 0.97 3
Variovorax sp. OAS795 0.22 ABID97_RS08425 tryptophan synthase subunit alpha 0.33 ABID97_RS05250 anthranilate synthase component I 0.87 1
Caulobacter crescentus NA1000 0.22 CCNA_03657 tryptophan synthase alpha chain 0.27 CCNA_01972 anthranilate synthase component I 0.95 5
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_03657 tryptophan synthase alpha chain 0.27 CCNA_01972 anthranilate synthase component I low > 67
Ralstonia solanacearum GMI1000 0.21 RS_RS09955 tryptophan synthase subunit alpha 0.34 RS_RS14430 anthranilate synthase component I 0.55 9
Pantoea sp. MT58 0.21 IAI47_09165 tryptophan synthase subunit alpha 0.23 IAI47_09190 anthranilate synthase component 1 0.98 4
Azospirillum sp. SherDot2 0.21 MPMX19_02737 Tryptophan synthase alpha chain 0.29 MPMX19_00893 Anthranilate synthase component 1 low > 112
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS11320 tryptophan synthase subunit alpha 0.28 A4249_RS06155 anthranilate synthase component I
Ralstonia solanacearum PSI07 0.21 RPSI07_RS14740 tryptophan synthase subunit alpha 0.34 RPSI07_RS10755 anthranilate synthase component I
Ralstonia solanacearum UW163 0.21 UW163_RS11150 tryptophan synthase subunit alpha 0.34 UW163_RS07140 anthranilate synthase component I
Ralstonia solanacearum IBSBF1503 0.21 RALBFv3_RS02575 tryptophan synthase subunit alpha 0.34 RALBFv3_RS06485 anthranilate synthase component I
Klebsiella michiganensis M5al 0.21 BWI76_RS11840 tryptophan synthase subunit alpha 0.23 BWI76_RS11860 anthranilate synthase component I 0.92 5
Herbaspirillum seropedicae SmR1 0.21 HSERO_RS16470 tryptophan synthase subunit alpha 0.35 HSERO_RS19435 anthranilate synthase subunit I 0.71 5
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_1740 trpA tryptophan synthase subunit alpha (RefSeq) 0.27 DvMF_1746 Anthranilate synthase (RefSeq) 0.84 18
Paraburkholderia graminis OAS925 0.21 ABIE53_004811 tryptophan synthase alpha chain 0.34 ABIE53_003640 anthranilate synthase component 1 0.73 1
Dickeya dianthicola 67-19 0.20 HGI48_RS10460 tryptophan synthase subunit alpha 0.23 HGI48_RS10485 anthranilate synthase component 1 0.83 2
Dickeya dianthicola ME23 0.20 DZA65_RS10940 tryptophan synthase subunit alpha 0.23 DZA65_RS10965 anthranilate synthase component 1 0.95 2
Dickeya dadantii 3937 0.20 DDA3937_RS10460 tryptophan synthase subunit alpha 0.22 DDA3937_RS10485 anthranilate synthase component 1 0.94 2
Xanthomonas campestris pv. campestris strain 8004 0.20 Xcc-8004.1967.1 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.35 Xcc-8004.608.1 Anthranilate synthase, aminase component (EC 4.1.3.27) 0.94 4
Enterobacter asburiae PDN3 0.20 EX28DRAFT_0932 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.22 EX28DRAFT_0936 anthranilate synthase, component I (EC 4.1.3.27) 0.80 4
Rahnella sp. WP5 0.20 EX31_RS09980 tryptophan synthase subunit alpha 0.22 EX31_RS09955 anthranilate synthase component 1 0.98 1
Enterobacter sp. TBS_079 0.20 MPMX20_02514 Tryptophan synthase alpha chain 0.22 MPMX20_02510 Anthranilate synthase component 1 0.93 6
Escherichia fergusonii Becca 0.20 EFB2_02666 Tryptophan synthase alpha chain 0.23 EFB2_02662 Anthranilate synthase component 1 low > 86
Escherichia coli ECOR38 0.19 HEPCGN_25515 trpA tryptophan synthase subunit alpha 0.22 HEPCGN_25535 trpE anthranilate synthase component I 0.98 2
Escherichia coli Nissle 1917 0.19 ECOLIN_RS07595 tryptophan synthase subunit alpha 0.23 ECOLIN_RS07615 anthranilate synthase component I
Escherichia coli BL21 0.19 ECD_01234 tryptophan synthase, alpha subunit 0.23 ECD_01238 component I of anthranilate synthase 0.59 45
Escherichia coli BW25113 0.19 b1260 trpA tryptophan synthase subunit alpha (NCBI) 0.23 b1264 trpE anthranilate synthase component I (NCBI) 0.85 52
Escherichia coli HS(pFamp)R (ATCC 700891) 0.19 OHPLBJKB_02423 Tryptophan synthase alpha chain 0.23 OHPLBJKB_02419 Anthranilate synthase component 1 low > 73
Erwinia tracheiphila SCR3 0.19 LU632_RS12775 trpA tryptophan synthase subunit alpha 0.23 LU632_RS12755 anthranilate synthase component 1 0.61 3
Pectobacterium carotovorum WPP14 0.19 HER17_RS10940 tryptophan synthase subunit alpha 0.22 HER17_RS10915 anthranilate synthase component 1 0.98 2
Escherichia coli ECOR27 0.19 NOLOHH_20335 trpA tryptophan synthase subunit alpha 0.23 NOLOHH_20315 trpE anthranilate synthase component I 0.91 10
Escherichia coli ECRC100 0.19 OKFHMN_02675 trpA tryptophan synthase subunit alpha 0.23 OKFHMN_02655 trpE anthranilate synthase component I low > 80
Escherichia coli ECRC101 0.19 MCAODC_15590 trpA tryptophan synthase subunit alpha 0.23 MCAODC_15610 trpE anthranilate synthase component I 0.88 6
Escherichia coli ECRC102 0.19 NIAGMN_26845 trpA tryptophan synthase subunit alpha 0.23 NIAGMN_26825 trpE anthranilate synthase component I
Escherichia coli ECRC99 0.19 KEDOAH_26075 trpA tryptophan synthase subunit alpha 0.23 KEDOAH_26095 trpE anthranilate synthase component I
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_06065 tryptophan synthase, alpha chain 0.34 H281DRAFT_05715 anthranilate synthase, component I 0.53 14
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.19 GFF2726 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.23 GFF2722 Anthranilate synthase, aminase component (EC 4.1.3.27) low > 78
Escherichia coli ECRC98 0.19 JDDGAC_05220 trpA tryptophan synthase subunit alpha 0.23 JDDGAC_05200 trpE anthranilate synthase component I 0.92 5
Castellaniella sp019104865 MT123 0.19 ABCV34_RS08430 tryptophan synthase subunit alpha 0.31 ABCV34_RS10280 anthranilate synthase component I
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS33865 tryptophan synthase alpha chain 0.34 BPHYT_RS17390 anthranilate synthase subunit I 0.92 3
Paraburkholderia sabiae LMG 24235 0.18 QEN71_RS17655 tryptophan synthase subunit alpha 0.35 QEN71_RS27550 anthranilate synthase component I 0.97 2
Sphingomonas koreensis DSMZ 15582 0.18 Ga0059261_0239 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.27 Ga0059261_0256 anthranilate synthase component I, non-proteobacterial lineages 0.90 4

Not shown: 11 genomes with orthologs for BBR_RS15810 only; 12 genomes with orthologs for BBR_RS16085 only